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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical actin cytoskeleton
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Accession:GO:0030864 term browser browse the term
Definition:The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.


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cortical actin cytoskeleton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN1 actinin alpha 1 is_active_in
located_in		 IBA
ISO		 GO_Central
RGD		 PMID:15505042 GO_REF:0000033 RGD:1359754 NCBI chr 7:92,550,132...92,644,842
Ensembl chr 7:92,550,007...92,644,842 		JBrowse link
G ACTN2 actinin alpha 2 is_active_in
located_in		 IBA
ISO		 GO_Central
RGD		 PMID:15505042 GO_REF:0000033 RGD:1359754 NCBI chr14:54,670,727...54,742,717
Ensembl chr14:54,666,623...54,742,778 		JBrowse link
G ACTN4 actinin alpha 4 located_in ISO (MGI:3692220|PMID:16837921) UniProt PMID:16837921 MGI:3692220 NCBI chr 6:47,493,834...47,565,999
Ensembl chr 6:47,493,919...47,565,998 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 located_in ISO (PMID:11546812) UniProt PMID:11546812 NCBI chr 7:87,889,384...88,222,854 JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:95,811,485...95,840,576
Ensembl chr 6:95,812,179...95,840,570 		JBrowse link
G CDH1 cadherin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986 		JBrowse link
G CDH2 cadherin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:112,396,713...112,629,073
Ensembl chr 6:112,396,721...112,628,432 		JBrowse link
G CFL1 cofilin 1 located_in ISO (PMID:15004221), (PMID:15548599) MGI PMID:15004221 PMID:15548599 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035 		JBrowse link
G CLDN5 claudin 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:51,161,490...51,162,382
Ensembl chr14:51,161,042...51,163,482 		JBrowse link
G CORO1A coronin 1A located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,898...18,342,396 		JBrowse link
G CTTN cortactin is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813 		JBrowse link
G DBN1 drebrin 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,495,796 		JBrowse link
G DBNL drebrin like is_active_in IBA GO_Central GO_REF:0000033 NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein located_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,169,709...1,637,171
Ensembl chr17:1,170,208...1,637,114 		JBrowse link
G DSTN destrin, actin depolymerizing factor located_in ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:25,998,830...26,050,354
Ensembl chr17:26,043,079...26,050,353 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 located_in ISO (PMID:19158340) UniProt PMID:19158340 NCBI chr 1:92,421,235...92,425,053
Ensembl chr 1:92,421,230...92,425,044 		JBrowse link
G FLOT1 flotillin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,253,157...23,265,165
Ensembl chr 7:23,253,162...23,265,106 		JBrowse link
G FLOT2 flotillin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:45,102,205...45,120,503
Ensembl chr12:45,101,531...45,120,455 		JBrowse link
G GMFB glia maturation factor beta is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 1:183,846,672...183,863,396
Ensembl chr 1:183,846,680...183,863,398 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,307,008...261,372,848 		JBrowse link
G GYS2 glycogen synthase 2 located_in ISO PMID:9003423 UniProt PMID:9003423 RGD:8553883 NCBI chr 5:51,862,952...51,915,153
Ensembl chr 5:51,862,863...51,917,757 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,144...138,889,281 		JBrowse link
G HIP1 huntingtin interacting protein 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 3:10,416,418...10,578,374
Ensembl chr 3:10,416,475...10,578,366 		JBrowse link
G HIP1R huntingtin interacting protein 1 related is_active_in IBA GO_Central GO_REF:0000033 NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:53,020,479...53,129,964
Ensembl chr 7:52,958,106...53,129,958 		JBrowse link
G LANCL2 LanC like glutathione S-transferase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:48,550,752...48,593,055
Ensembl chr18:48,550,944...48,593,455 		JBrowse link
G LASP1 LIM and SH3 protein 1 located_in ISS UniProt GO_REF:0000024 NCBI chr12:23,222,706...23,267,209
Ensembl chr12:23,222,708...23,267,855 		JBrowse link
G LLGL1 LLGL scribble cell polarity complex component 1 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:60,487,337...60,500,423
Ensembl chr12:60,487,343...60,500,447 		JBrowse link
G LLGL2 LLGL scribble cell polarity complex component 2 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr12:5,809,066...5,846,165
Ensembl chr12:5,809,069...5,846,162 		JBrowse link
G MED28 mediator complex subunit 28 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,624,096...12,633,251
Ensembl chr 8:12,624,109...12,635,334 		JBrowse link
G MISP mitotic spindle positioning located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,607,185...77,619,124
Ensembl chr 2:77,602,142...77,619,087 		JBrowse link
G MLPH melanophilin is_active_in
located_in		 IBA
ISO		 (PMID:16247022) GO_Central
MGI		 PMID:16247022 GO_REF:0000033 NCBI chr15:137,173,962...137,219,724
Ensembl chr15:137,174,009...137,219,713 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:13,660,388...13,682,311
Ensembl chr 6:13,660,392...13,682,316 		JBrowse link
G MYADM myeloid associated differentiation marker located_in ISO (PMID:21325632), (PMID:23264465) UniProt PMID:21325632 PMID:23264465 NCBI chr 6:56,236,306...56,278,577
Ensembl chr 6:56,236,311...56,244,185 		JBrowse link
G MYO1A myosin IA located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:22,338,024...22,363,528
Ensembl chr 5:22,338,029...22,363,568 		JBrowse link
G MYO1F myosin IF located_in ISO (PMID:17023661) MGI PMID:17023661 NCBI chr 2:70,753,143...70,792,938
Ensembl chr 2:70,753,138...70,792,936 		JBrowse link
G MYRIP myosin VIIA and Rab interacting protein is_active_in IBA GO_Central GO_REF:0000033 NCBI chr13:24,347,574...24,556,743
Ensembl chr13:24,347,660...24,556,735 		JBrowse link
G MYZAP myocardial zonula adherens protein located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,287,622...114,386,418
Ensembl chr 1:114,287,627...114,386,427 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,653,869...46,726,421
Ensembl chr14:46,653,900...46,731,999 		JBrowse link
G PDLIM2 PDZ and LIM domain 2 located_in ISO RGD PMID:15505042 RGD:1359754 NCBI chr14:6,834,116...6,848,536
Ensembl chr14:6,834,779...6,848,526 		JBrowse link
G PJVK pejvakin located_in IEA Ensembl GO_REF:0000107 NCBI chr15:84,157,864...84,165,763
Ensembl chr15:84,158,639...84,165,906 		JBrowse link
G PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:96,707,397...96,833,431
Ensembl chr 3:96,709,059...96,833,410 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,403...74,940,362 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B located_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,319,123...26,337,089
Ensembl chr12:26,319,124...26,336,562 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,299...78,134,105 		JBrowse link
G RDX radixin located_in ISO (MGI:5645204|PMID:21047789) UniProt PMID:21047789 MGI:5645204 RGD:10054076 NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,447...38,322,097 		JBrowse link
G RSL1D1 ribosomal L1 domain containing 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 3:31,278,394...31,291,205
Ensembl chr 3:31,278,852...31,293,246 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO RGD PMID:16356937 RGD:1624121 NCBI chr 5:64,287,529...64,312,917
Ensembl chr 5:64,285,015...64,313,612 		JBrowse link
G SHROOM1 shroom family member 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:135,147,828...135,152,540
Ensembl chr 2:135,149,046...135,152,494 		JBrowse link
G SHROOM2 shroom family member 2 located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:6,296,212...6,450,401
NCBI chr  Y:4,753,733...4,785,766
Ensembl chr  X:6,296,219...6,448,992 		JBrowse link
G SHROOM4 shroom family member 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:44,301,956...44,543,969
Ensembl chr  X:44,332,620...44,543,337 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 4:91,573,470...91,640,057
Ensembl chr 4:91,485,067...91,640,063 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 1:268,936,120...269,002,261
Ensembl chr 1:268,936,025...269,002,256 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:5,683,414...5,739,418
Ensembl chr 2:5,695,836...5,739,415 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 6:48,729,839...48,812,799
Ensembl chr 6:48,729,419...48,812,796 		JBrowse link
G SPTBN5 spectrin beta, non-erythrocytic 5 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 1:129,461,598...129,514,380
Ensembl chr 1:129,462,568...129,511,568 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 located_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr14:41,125,819...41,169,582
Ensembl chr14:41,125,869...41,169,578 		JBrowse link
G UTRN utrophin ISO RGD PMID:10760950 RGD:1580541 NCBI chr 1:20,514,264...21,047,927
Ensembl chr 1:20,514,260...21,048,484 		JBrowse link
G WDR1 WD repeat domain 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 8:6,413,338...6,452,383
Ensembl chr 8:6,413,347...6,452,346 		JBrowse link
G ZNF774 zinc finger protein 774 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:52,985,669...52,994,797
Ensembl chr 7:52,958,106...53,129,958 		JBrowse link
actin cap term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:76,691,275...76,729,269
Ensembl chr 3:76,691,280...76,729,252 		JBrowse link
G CALD1 caldesmon 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,307,008...261,372,848 		JBrowse link
G WASL WASP like actin nucleation promoting factor located_in IEA Ensembl GO_REF:0000107 NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506 		JBrowse link
actomyosin contractile ring term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANLN anillin, actin binding protein located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr18:37,647,952...37,710,939
Ensembl chr18:37,647,961...37,708,575 		JBrowse link
G MAEA macrophage erythroblast attacher, E3 ubiquitin ligase located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:543,281...568,437
Ensembl chr 8:543,291...568,452 		JBrowse link
G MYH2 myosin, heavy chain 2, skeletal muscle, adult located_in IEA Ensembl GO_REF:0000107 NCBI chr12:55,252,974...55,278,820 JBrowse link
G MYH9 myosin heavy chain 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472 		JBrowse link
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 located_in ISO (PMID:9265651) MGI PMID:9265651 NCBI chr 7:57,100,212...57,145,278
Ensembl chr 7:57,102,757...57,146,751 		JBrowse link
G RTKN rhotekin is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 3:68,598,560...68,613,633
Ensembl chr 3:68,598,249...68,613,631 		JBrowse link
cuticular plate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 4:46,701,276...46,723,548
Ensembl chr 4:46,701,045...46,725,197 		JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 6:14,392,220...14,420,663
Ensembl chr 6:14,391,857...14,420,663 		JBrowse link
G CIB2 calcium and integrin binding family member 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:47,807,806...47,813,400
Ensembl chr 7:47,788,646...47,813,399 		JBrowse link
G FCHSD1 FCH and double SH3 domains 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:143,289,854...143,301,921
Ensembl chr 2:143,289,859...143,301,900 		JBrowse link
G KNCN kinocilin located_in
is_active_in		 IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:164,938,947...164,942,879
Ensembl chr 6:164,939,388...164,943,161 		JBrowse link
G MYO1E myosin IE ISO RGD PMID:12486594 RGD:1298992 NCBI chr 1:112,677,545...112,902,005
Ensembl chr 1:112,677,821...112,901,993 		JBrowse link
G OCM oncomodulin ISO RGD PMID:16120789 RGD:7175527 NCBI chr 3:5,239,438...5,245,329 JBrowse link
G PVALB parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chr 5:10,953,559...10,973,300
Ensembl chr 5:10,955,491...10,973,289 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,130,360...9,239,023
Ensembl chr 1:9,130,338...9,239,029 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:91,573,470...91,640,057
Ensembl chr 4:91,485,067...91,640,063 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 located_in ISO (PMID:18796539) MGI PMID:18796539 NCBI chr 1:268,936,120...269,002,261
Ensembl chr 1:268,936,025...269,002,256 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:86,585,225...86,784,316
Ensembl chr 3:86,585,054...86,784,149 		JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,977,890...33,047,982
Ensembl chr17:32,977,723...33,048,181 		JBrowse link
spectrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCB protein kinase C beta part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 4:91,573,470...91,640,057
Ensembl chr 4:91,485,067...91,640,063 		JBrowse link
G SPTB spectrin beta, erythrocytic part_of IEA InterPro GO_REF:0000002 NCBI chr 7:88,812,717...88,954,471
Ensembl chr 7:88,812,718...88,954,306 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 part_of IEA InterPro GO_REF:0000002 NCBI chr 3:86,585,225...86,784,316
Ensembl chr 3:86,585,054...86,784,149 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 part_of IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:5,683,414...5,739,418
Ensembl chr 2:5,695,836...5,739,415 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 part_of IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:48,729,839...48,812,799
Ensembl chr 6:48,729,419...48,812,796 		JBrowse link
terminal web term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COBL cordon-bleu WH2 repeat protein located_in ISO (MGI:5621262|PMID:22114352) UniProt PMID:22114352 MGI:5621262 NCBI chr 9:136,850,521...137,055,249 JBrowse link
G HFE homeostatic iron regulator ISO RGD PMID:16208485 RGD:1582698 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G KRT19 keratin 19 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:21,115,453...21,119,115
Ensembl chr12:21,115,448...21,119,107 		JBrowse link
G PLS1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:83,307,692...83,434,133
Ensembl chr13:83,308,007...83,434,128 		JBrowse link
G VCL vinculin located_in ISS AgBase GO_REF:0000024 NCBI chr14:76,700,143...76,811,875
Ensembl chr14:76,700,173...76,811,869 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18389
    cellular anatomical entity 18156
      cytoplasm 10350
        cell cortex 314
          cortical cytoskeleton 120
            cortical actin cytoskeleton 88
              actin cap 4
              actin cortical patch + 0
              actomyosin contractile ring + 6
              cuticular plate 13
              macropinocytic cup cytoskeleton 0
              spectrin 6
              terminal web 5
Path 2
Term Annotations click to browse term
  cellular_component 18389
    cellular anatomical entity 18156
      organelle 12170
        non-membrane-bounded organelle 4496
          intracellular non-membrane-bounded organelle 4496
            cytoskeleton 2162
              actin cytoskeleton 506
                cortical actin cytoskeleton 88
                  actin cap 4
                  actin cortical patch + 0
                  actomyosin contractile ring + 6
                  cuticular plate 13
                  macropinocytic cup cytoskeleton 0
                  spectrin 6
                  terminal web 5
paths to the root