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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical actin cytoskeleton
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Accession:GO:0030864 term browser browse the term
Definition:The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.

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cortical actin cytoskeleton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN1 actinin alpha 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:46,089,989...46,196,897
Ensembl chr24:46,085,751...46,196,886 		JBrowse link
G ACTN2 actinin alpha 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:73,827,900...73,904,516
Ensembl chr25:73,827,874...73,905,146 		JBrowse link
G ACTN3 actinin alpha 3 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:7,708,595...7,724,634
Ensembl chr 1:7,705,725...7,724,589 		JBrowse link
G ACTN4 actinin alpha 4 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:33,290,639...33,373,059
Ensembl chr 6:33,290,622...33,374,693 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 located_in IEA Ensembl GO_REF:0000107 NCBI chr29:4,009,921...4,364,226
Ensembl chr29:4,106,732...4,359,516 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:92,833,112...92,865,258
Ensembl chr20:92,829,735...92,864,697 		JBrowse link
G CDH2 cadherin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,426,381...52,652,986
Ensembl chr18:52,426,077...52,654,828 		JBrowse link
G CFL1 cofilin 1 located_in ISO (PMID:15004221), (PMID:15548599) MGI PMID:15004221 PMID:15548599 NCBI chr 1:8,408,560...8,410,564 JBrowse link
G CLDN5 claudin 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr19:6,227,881...6,230,199
Ensembl chr19:6,228,965...6,229,621 		JBrowse link
G CORO1A coronin 1A located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,482,269...26,488,537
Ensembl chr 5:26,480,753...26,487,929 		JBrowse link
G COTL1 coactosin like F-actin binding protein 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:69,966,655...70,019,338
Ensembl chr 5:69,967,900...70,019,307 		JBrowse link
G CTTN cortactin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:4,139,045...4,176,962
Ensembl chr 1:4,137,814...4,176,446 		JBrowse link
G DBN1 drebrin 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:79,468,010...79,484,603
Ensembl chr23:79,467,647...79,484,592 		JBrowse link
G DBNL drebrin like located_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:14,610,196...14,627,363
Ensembl chr21:14,608,571...14,627,321 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein located_in ISO (PMID:19158340) UniProt PMID:19158340 NCBI chr 8:11,211,230...11,632,278 JBrowse link
G DSTN destrin, actin depolymerizing factor located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:46,636,111...46,672,771
Ensembl chr 2:46,635,954...46,673,165 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 located_in ISO (PMID:19158340) UniProt PMID:19158340 NCBI chr17:1,626,701...1,630,445
Ensembl chr17:1,627,901...1,630,150 		JBrowse link
G FLOT1 flotillin 1 located_in ISO (PMID:24046456) UniProt PMID:24046456 NCBI chr17:41,714,354...41,725,820
Ensembl chr17:41,714,402...41,725,397 		JBrowse link
G FLOT2 flotillin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,639,403...22,658,311
Ensembl chr16:22,639,381...22,658,194 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938 		JBrowse link
G GYS2 glycogen synthase 2 located_in ISO PMID:9003423 UniProt PMID:9003423 RGD:8553883 NCBI chr11:21,400,582...21,464,438
Ensembl chr11:21,398,869...21,463,277 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:59,225,768...59,255,744
Ensembl chr22:59,225,750...59,256,243 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 located_in ISO (PMID:28089576) MGI PMID:28089576 NCBI chr29:9,363,273...9,485,644
Ensembl chr29:9,362,926...9,485,526 		JBrowse link
G LANCL2 LanC like glutathione S-transferase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr21:3,435,435...3,503,802
Ensembl chr21:3,434,909...3,501,335 		JBrowse link
G LASP1 LIM and SH3 protein 1 located_in ISO PMID:10806114 UniProt PMID:10806114 RGD:8553950 NCBI chr16:67,268,442...67,320,473
Ensembl chr16:67,267,940...67,320,373 		JBrowse link
G LLGL1 LLGL scribble cell polarity complex component 1 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:17,266,648...17,285,460
Ensembl chr16:17,266,684...17,284,076 		JBrowse link
G LLGL2 LLGL scribble cell polarity complex component 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:46,103,080...46,151,576
Ensembl chr16:46,102,939...46,135,594 		JBrowse link
G LOC103233229 cadherin-1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G MED28 mediator complex subunit 28 located_in IEA Ensembl GO_REF:0000107 NCBI chr27:32,599,370...32,609,956
Ensembl chr27:32,600,058...32,609,941 		JBrowse link
G MISP mitotic spindle positioning located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:505,841...520,758
Ensembl chr 6:506,482...520,827 		JBrowse link
G MLPH melanophilin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:123,489,777...123,562,037
Ensembl chr10:123,491,702...123,562,906 		JBrowse link
G MOBP myelin associated oligodendrocyte basic protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:1,041,714...1,077,514
Ensembl chr22:1,041,783...1,079,241 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:53,802,594...53,827,763
Ensembl chr 5:53,805,020...53,827,648 		JBrowse link
G MYADM myeloid associated differentiation marker located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:46,559,943...46,568,057
Ensembl chr 6:46,566,968...46,567,936 		JBrowse link
G MYO1A myosin IA located_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,939,744...52,961,957
Ensembl chr11:52,936,090...52,961,486 		JBrowse link
G MYO1F myosin IF located_in ISO (PMID:17023661) MGI PMID:17023661 NCBI chr 6:7,872,060...7,920,845 JBrowse link
G MYRIP myosin VIIA and Rab interacting protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:1,369,820...1,765,121
Ensembl chr22:1,370,001...1,765,311 		JBrowse link
G MYZAP myocardial zonula adherens protein located_in IEA Ensembl GO_REF:0000107 NCBI chr26:25,822,286...25,916,191
Ensembl chr26:25,821,849...25,916,205 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,474,479...12,572,144
Ensembl chr19:12,474,468...12,572,250 		JBrowse link
G PDLIM2 PDZ and LIM domain 2 located_in ISO RGD PMID:15505042 RGD:1359754 NCBI chr 8:20,658,642...20,674,915
Ensembl chr 8:20,659,361...20,674,900 		JBrowse link
G PJVK pejvakin located_in ISO (PMID:28089576) MGI PMID:28089576 NCBI chr10:64,004,113...64,013,025
Ensembl chr10:64,005,259...64,014,571 		JBrowse link
G PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:63,488,305...63,617,146
Ensembl chr14:63,488,773...63,609,021 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A located_in ISO (PMID:15996550) MGI PMID:15996550 NCBI chr21:53,744,202...54,129,709
Ensembl chr21:53,747,857...54,127,005 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B located_in IEA Ensembl GO_REF:0000107 NCBI chr16:43,188,400...43,205,621
Ensembl chr16:43,188,022...43,205,680 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 located_in ISO PMID:21047789
(PMID:21047789)		 UniProt PMID:21047789 RGD:10054076 NCBI chr11:43,954,517...43,979,068
Ensembl chr11:43,957,425...43,978,047 		JBrowse link
G RDX radixin located_in ISO (MGI:5645204|PMID:21047789) UniProt PMID:21047789 MGI:5645204 RGD:10054076 NCBI chr 1:101,554,640...101,647,765
Ensembl chr 1:101,554,334...101,623,093 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO RGD PMID:16356937 RGD:1624121 NCBI chr11:6,384,073...6,418,620
Ensembl chr11:6,383,956...6,416,337 		JBrowse link
G SHROOM1 shroom family member 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:35,640,158...35,649,590
Ensembl chr23:35,639,211...35,643,820 		JBrowse link
G SHROOM2 shroom family member 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:8,242,714...8,405,051
Ensembl chr  X:8,345,056...8,405,552 		JBrowse link
G SHROOM3 shroom family member 3 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:25,185,130...25,279,765
Ensembl chr 7:25,215,232...25,283,214 		JBrowse link
G SHROOM4 shroom family member 4 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:47,392,156...47,618,816
Ensembl chr  X:47,397,570...47,616,973 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 located_in ISO (PMID:18347014) UniProt PMID:18347014 NCBI chr20:89,974,567...90,007,977
Ensembl chr20:90,002,030...90,008,033 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:5,238,246...5,314,204
Ensembl chr20:5,238,447...5,313,887 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:9,503,752...9,585,297
Ensembl chr12:9,503,367...9,585,268 		JBrowse link
G SPTB spectrin beta, erythrocytic located_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:41,957,438...42,038,522
Ensembl chr24:41,978,595...42,038,516 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:52,266,197...52,487,111
Ensembl chr14:52,262,416...52,487,112 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:7,543,035...7,588,125
Ensembl chr 1:7,556,953...7,590,720 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:34,926,413...35,036,611
Ensembl chr 6:34,930,519...35,035,719 		JBrowse link
G SPTBN5 spectrin beta, non-erythrocytic 5 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:41,090,023...41,137,645
Ensembl chr26:41,091,478...41,135,932 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 located_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr11:105,020,972...105,072,660 JBrowse link
G UTRN utrophin ISO RGD PMID:10760950 RGD:1580541 NCBI chr13:28,354,810...28,949,508
Ensembl chr13:28,354,588...28,944,119 		JBrowse link
G WDR1 WD repeat domain 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:39,929,749...39,973,892
Ensembl chr27:39,929,787...39,974,012 		JBrowse link
actin cap term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,740,432...41,780,045
Ensembl chr14:41,739,968...41,779,964 		JBrowse link
G CALD1 caldesmon 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr21:103,435,238...103,671,901
Ensembl chr21:103,469,975...103,672,699 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938 		JBrowse link
G WASL WASP like actin nucleation promoting factor located_in IEA Ensembl GO_REF:0000107 NCBI chr21:92,480,392...92,546,725
Ensembl chr21:92,482,918...92,546,481 		JBrowse link
actomyosin contractile ring term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANLN anillin actin binding protein located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:22,034,213...22,099,207
Ensembl chr21:22,034,259...22,099,158 		JBrowse link
G LOC103242383 myosin-2 located_in ISO (PMID:15548599) MGI PMID:15548599 NCBI chr16:9,863,336...9,891,271 JBrowse link
G MAEA macrophage erythroblast attacher, E3 ubiquitin ligase located_in ISO (PMID:16510120) UniProt PMID:16510120 NCBI chr27:47,425,276...47,473,618
Ensembl chr27:47,425,185...47,473,626 		JBrowse link
G MYH9 myosin heavy chain 9 located_in ISO (PMID:11029059) UniProt PMID:11029059 NCBI chr19:18,985,709...19,093,304
Ensembl chr19:18,986,598...19,052,671 		JBrowse link
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 located_in ISO (PMID:9265651) MGI PMID:9265651 NCBI chr26:6,260,509...6,302,717
Ensembl chr26:6,260,349...6,302,673 		JBrowse link
G RTKN rhotekin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:32,835,660...32,851,799
Ensembl chr14:32,837,546...32,855,912 		JBrowse link
cuticular plate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 8:85,135,956...85,160,806
Ensembl chr 8:85,137,528...85,160,855 		JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 5:54,503,635...54,538,304
Ensembl chr 5:54,504,082...54,538,441 		JBrowse link
G CIB2 calcium and integrin binding family member 2 located_in ISO (PMID:26426422) UniProt PMID:26426422 NCBI chr26:5,222,657...5,248,133
Ensembl chr26:5,222,902...5,248,191 		JBrowse link
G FCHSD1 FCH and double SH3 domains 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr23:44,267,276...44,277,754
Ensembl chr23:44,267,798...44,277,678 		JBrowse link
G KNCN kinocilin located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:86,254,194...86,275,797
Ensembl chr20:86,256,803...86,260,298 		JBrowse link
G MYO1E myosin IE ISO RGD PMID:12486594 RGD:1298992 NCBI chr26:24,138,462...24,378,602
Ensembl chr26:24,138,829...24,379,143 		JBrowse link
G PVALB parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chr19:19,501,100...19,520,031
Ensembl chr19:19,501,293...19,517,340 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:85,468,837...85,549,351
Ensembl chr13:85,468,479...85,549,988 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:5,238,246...5,314,204
Ensembl chr20:5,238,447...5,313,887 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 located_in ISO (PMID:18796539) MGI PMID:18796539 NCBI chr12:9,503,752...9,585,297
Ensembl chr12:9,503,367...9,585,268 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 located_in ISO (PMID:18796539) MGI PMID:18796539 NCBI chr14:52,266,197...52,487,111
Ensembl chr14:52,262,416...52,487,112 		JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,903,305...54,002,599
Ensembl chr 2:53,903,842...53,979,535 		JBrowse link
spectrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCB protein kinase C beta part_of ISO (MGI:1346761|PMID:10534118) CACAO PMID:10534118 MGI:1346761 NCBI chr 5:21,558,608...21,940,536
Ensembl chr 5:21,558,441...21,943,864 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr20:5,238,246...5,314,204
Ensembl chr20:5,238,447...5,313,887 		JBrowse link
G SPTB spectrin beta, erythrocytic part_of IEA InterPro GO_REF:0000002 NCBI chr24:41,957,438...42,038,522
Ensembl chr24:41,978,595...42,038,516 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 part_of IEA InterPro GO_REF:0000002 NCBI chr14:52,266,197...52,487,111
Ensembl chr14:52,262,416...52,487,112 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 part_of IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:7,543,035...7,588,125
Ensembl chr 1:7,556,953...7,590,720 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 part_of IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 6:34,926,413...35,036,611
Ensembl chr 6:34,930,519...35,035,719 		JBrowse link
terminal web term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COBL cordon-bleu WH2 repeat protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:7,501,647...7,803,175
Ensembl chr21:7,598,126...7,803,177 		JBrowse link
G HFE homeostatic iron regulator ISO RGD PMID:16208485 RGD:1582698 NCBI chr17:46,159,770...46,168,831
Ensembl chr17:46,156,685...46,164,649 		JBrowse link
G KRT19 keratin 19 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,714,497...64,719,805
Ensembl chr16:64,714,970...64,719,678 		JBrowse link
G PLS1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,919,807...48,031,158
Ensembl chr15:47,919,823...48,003,805 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17806
    cellular anatomical entity 17706
      cytoplasm 11133
        cell cortex 321
          cortical cytoskeleton 122
            cortical actin cytoskeleton 85
              actin cap 4
              actin cortical patch + 0
              actomyosin contractile ring + 6
              cuticular plate 12
              macropinocytic cup cytoskeleton 0
              spectrin 6
              terminal web 4
Path 2
Term Annotations click to browse term
  cellular_component 17806
    cellular anatomical entity 17706
      organelle 13063
        non-membrane-bounded organelle 4784
          intracellular non-membrane-bounded organelle 4784
            cytoskeleton 2211
              actin cytoskeleton 533
                cortical actin cytoskeleton 85
                  actin cap 4
                  actin cortical patch + 0
                  actomyosin contractile ring + 6
                  cuticular plate 12
                  macropinocytic cup cytoskeleton 0
                  spectrin 6
                  terminal web 4
paths to the root