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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical actin cytoskeleton
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Accession:GO:0030864 term browser browse the term
Definition:The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.


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cortical actin cytoskeleton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN1 actinin alpha 1 located_in ISO RGD PMID:15505042 RGD:1359754 NCBI chr 8:42,714,806...42,808,318
Ensembl chr 8:42,712,142...42,808,323 		JBrowse link
G ACTN2 actinin alpha 2 located_in ISO RGD PMID:15505042 RGD:1359754 NCBI chr 4:3,348,529...3,415,275
Ensembl chr 4:3,348,449...3,415,273 		JBrowse link
G ACTN4 actinin alpha 4 located_in ISO (MGI:3692220|PMID:16837921) UniProt PMID:16837921 MGI:3692220 NCBI chr 1:114,354,993...114,427,997
Ensembl chr 1:114,309,693...114,427,991 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,076,313...49,310,564
Ensembl chr 3:49,076,642...49,308,221 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 located_in ISO (PMID:15004221) MGI PMID:15004221 NCBI chr15:2,886,661...2,913,975 JBrowse link
G CDH1 cadherin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878 		JBrowse link
G CDH2 cadherin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:60,736,760...60,950,477
Ensembl chr 7:60,736,760...60,951,034 		JBrowse link
G CFL1 cofilin 1 located_in ISO (PMID:15004221), (PMID:15548599) MGI PMID:15004221 PMID:15548599 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212 		JBrowse link
G CLDN5 claudin 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr26:29,702,464...29,704,950
Ensembl chr26:29,703,683...29,704,339 		JBrowse link
G CORO1A coronin 1A located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,161,850...18,167,915
Ensembl chr 6:18,160,601...18,167,818 		JBrowse link
G DHRS13 dehydrogenase/reductase 13 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:43,050,929...43,066,886
Ensembl chr 9:43,052,114...43,071,742 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein located_in IEA Ensembl GO_REF:0000107 NCBI chr16:36,531,754...36,943,033
Ensembl chr16:36,531,754...36,943,033 		JBrowse link
G DSTN destrin, actin depolymerizing factor located_in ISO (PMID:15548599) MGI PMID:15548599 NCBI chr24:5,394,972...5,402,443
Ensembl chr24:5,356,464...5,432,574 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 located_in ISO (PMID:19158340) UniProt PMID:19158340 NCBI chr12:35,576,576...35,581,339
Ensembl chr12:35,576,576...35,581,230 		JBrowse link
G FLOT1 flotillin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G GYS2 glycogen synthase 2 located_in ISO PMID:9003423 UniProt PMID:9003423 RGD:8553883 NCBI chr27:25,509,833...25,558,874
Ensembl chr27:25,509,655...25,558,844 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,683,869...53,791,136
Ensembl chr 3:53,683,791...53,792,186 		JBrowse link
G LANCL2 LanC like glutathione S-transferase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:6,131,536...6,237,232
Ensembl chr18:6,197,989...6,234,856 		JBrowse link
G LASP1 LIM and SH3 protein 1 located_in ISO PMID:10806114 UniProt PMID:10806114 RGD:8553950 NCBI chr 9:23,345,226...23,397,058
Ensembl chr 9:23,347,881...23,396,945 		JBrowse link
G LLGL1 LLGL scribble cell polarity complex component 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:41,314,807...41,332,687
Ensembl chr 5:41,315,152...41,332,896 		JBrowse link
G MED28 mediator complex subunit 28 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:62,887,095...62,895,588
Ensembl chr 3:62,890,515...62,895,562 		JBrowse link
G MISP mitotic spindle positioning located_in IEA Ensembl GO_REF:0000107 NCBI chr20:57,839,423...57,847,013
Ensembl chr20:57,838,731...57,843,219 		JBrowse link
G MLPH melanophilin located_in ISO (PMID:16247022) MGI PMID:16247022 NCBI chr25:48,121,499...48,167,535
Ensembl chr25:48,121,499...48,170,710 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,613,388...76,633,873
Ensembl chr 5:76,614,570...76,629,867 		JBrowse link
G MYADM myeloid associated differentiation marker located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:103,315,606...103,322,329 JBrowse link
G MYO1A myosin IA located_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,159,816...1,194,452
Ensembl chr10:1,159,812...1,193,153 		JBrowse link
G MYO1F myosin IF located_in ISO (PMID:17023661) MGI PMID:17023661 NCBI chr20:53,054,583...53,088,593
Ensembl chr20:53,054,585...53,089,115 		JBrowse link
G MYZAP myocardial zonula adherens protein located_in ISO (MGI:4947500|PMID:20093627) UniProt PMID:20093627 MGI:4947500 NCBI chr30:22,760,852...22,850,293 JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA Ensembl GO_REF:0000107 NCBI chr26:22,816,869...22,896,103
Ensembl chr26:22,816,551...22,894,196 		JBrowse link
G PDLIM2 PDZ and LIM domain 2 located_in ISO RGD PMID:15505042 RGD:1359754 NCBI chr25:34,684,954...34,699,144
Ensembl chr25:34,684,964...34,699,166 		JBrowse link
G PJVK pejvakin located_in IEA Ensembl GO_REF:0000107 NCBI chr36:22,080,574...22,087,537
Ensembl chr36:22,040,303...22,092,249 		JBrowse link
G PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:46,113,659...46,226,259
Ensembl chr10:46,114,348...46,224,363 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A located_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,251,791...20,563,315
Ensembl chr14:20,251,738...20,557,208 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,135,982...26,152,303
Ensembl chr 9:26,137,464...26,151,810 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr27:6,993,452...7,030,372
Ensembl chr27:6,993,452...7,017,316 		JBrowse link
G RDX radixin located_in ISO PMID:21047789
(MGI:5645204|PMID:21047789)		 UniProt PMID:21047789 MGI:5645204 RGD:10054076 NCBI chr 5:22,555,913...22,642,822
Ensembl chr 5:22,571,286...22,642,811 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO RGD PMID:16356937 RGD:1624121 NCBI chr27:38,612,206...38,638,212
Ensembl chr27:38,612,194...38,638,980 		JBrowse link
G SHROOM2 shroom family member 2 located_in ISO (PMID:16684770)
(MGI:3690292|PMID:16684770)		 HGNC-UCL
UniProt		 PMID:16684770 MGI:3690292 NCBI chr  X:6,499,570...6,642,738
Ensembl chr  X:6,499,354...6,641,946 		JBrowse link
G SHROOM4 shroom family member 4 located_in ISO (MGI:3690292|PMID:16684770) HGNC-UCL PMID:16684770 MGI:3690292 NCBI chr  X:43,366,921...43,639,525
Ensembl chr  X:43,369,472...43,639,302 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 located_in ISO (PMID:18347014) UniProt PMID:18347014 NCBI chr15:463,307...493,145
Ensembl chr15:463,237...493,140 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 located_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
G UTRN utrophin ISO RGD PMID:10760950 RGD:1580541 NCBI chr 1:35,727,531...36,225,533
Ensembl chr 1:35,677,814...36,224,065 		JBrowse link
actin cap term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,696,068...64,733,027
Ensembl chr10:64,696,111...64,730,553 		JBrowse link
G CALD1 caldesmon 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:13,087,419...13,279,648
Ensembl chr16:13,084,109...13,279,384 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G WASL WASP like actin nucleation promoting factor located_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,828,298...11,901,190
Ensembl chr14:11,828,687...11,899,788 		JBrowse link
actomyosin contractile ring term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANLN anillin, actin binding protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,805,113...47,854,749
Ensembl chr14:47,804,845...47,853,633 		JBrowse link
G MAEA macrophage erythroblast attacher, E3 ubiquitin ligase located_in ISO (PMID:16510120) UniProt PMID:16510120 NCBI chr 3:62,679,084...62,718,154
Ensembl chr 3:62,682,538...62,718,071 		JBrowse link
G MYH2 myosin heavy chain 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:34,810,791...34,838,177
Ensembl chr 5:34,810,921...34,837,904 		JBrowse link
G MYH9 myosin heavy chain 9 located_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:28,063,626...28,122,953
Ensembl chr10:28,063,624...28,122,953 		JBrowse link
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 located_in ISO (PMID:9265651) MGI PMID:9265651 NCBI chr30:39,270,852...39,309,507
Ensembl chr30:39,270,919...39,308,108 		JBrowse link
cuticular plate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chr29:35,551,836...35,572,985
Ensembl chr29:35,552,436...35,572,925 		JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 5:77,178,158...77,205,663
Ensembl chr 5:77,177,951...77,205,671 		JBrowse link
G CIB2 calcium and integrin binding family member 2 located_in ISO (PMID:26426422) UniProt PMID:26426422
G FCHSD1 FCH and double SH3 domains 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:36,601,969...36,612,262
Ensembl chr 2:36,602,460...36,612,199 		JBrowse link
G KNCN kinocilin located_in IEA Ensembl GO_REF:0000107 NCBI chr15:13,900,881...13,907,964
Ensembl chr15:13,903,036...13,907,967 		JBrowse link
G MYO1E myosin IE ISO RGD PMID:12486594 RGD:1298992 NCBI chr30:24,067,622...24,265,567
Ensembl chr30:24,068,283...24,265,311 		JBrowse link
G PVALB parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chr10:27,655,896...27,674,309
Ensembl chr10:27,655,905...27,707,332 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:47,346,214...47,457,417
Ensembl chr 1:47,343,668...47,455,937 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr38:23,052,046...23,118,933
Ensembl chr38:23,051,563...23,118,966 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 located_in ISO (PMID:18796539) MGI PMID:18796539 NCBI chr 9:54,953,751...55,015,475
Ensembl chr 9:54,953,747...55,015,376 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr10:55,429,989...55,571,917
Ensembl chr10:55,429,940...55,571,916 		JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,576,966...18,642,204
Ensembl chr24:18,578,138...18,642,198 		JBrowse link
spectrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCB protein kinase C beta part_of IEA Ensembl GO_REF:0000107 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr38:23,052,046...23,118,933
Ensembl chr38:23,051,563...23,118,966 		JBrowse link
G SPTB spectrin beta, erythrocytic part_of IEA InterPro GO_REF:0000002 NCBI chr 8:39,156,388...39,300,908
Ensembl chr 8:39,158,795...39,221,193 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 part_of IEA InterPro GO_REF:0000002 NCBI chr10:55,429,989...55,571,917
Ensembl chr10:55,429,940...55,571,916 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 part_of IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr18:50,631,053...50,670,428
Ensembl chr18:50,631,909...50,669,916 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 part_of IEA InterPro GO_REF:0000002 NCBI chr 1:113,167,251...113,243,071
Ensembl chr 1:113,168,484...113,240,934 		JBrowse link
terminal web term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COBL cordon-bleu WH2 repeat protein located_in ISO (MGI:5621262|PMID:22114352) UniProt PMID:22114352 MGI:5621262 NCBI chr18:2,206,957...2,386,333
Ensembl chr18:2,208,260...2,459,206 		JBrowse link
G HFE homeostatic iron regulator ISO RGD PMID:16208485 RGD:1582698 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G KRT19 keratin 19 located_in ISO (PMID:19321664) MGI PMID:19321664 NCBI chr 9:21,240,778...21,245,039 JBrowse link
G PLS1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr23:38,243,631...38,347,195
Ensembl chr23:38,243,024...38,347,202 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18010
    cellular anatomical entity 17733
      cytoplasm 10247
        cell cortex 291
          cortical cytoskeleton 102
            cortical actin cytoskeleton 71
              actin cap 4
              actin cortical patch + 0
              actomyosin contractile ring + 5
              cuticular plate 12
              macropinocytic cup cytoskeleton 0
              spectrin 6
              terminal web 4
Path 2
Term Annotations click to browse term
  cellular_component 18010
    cellular anatomical entity 17733
      organelle 12439
        non-membrane-bounded organelle 4720
          intracellular non-membrane-bounded organelle 4720
            cytoskeleton 2188
              actin cytoskeleton 486
                cortical actin cytoskeleton 71
                  actin cap 4
                  actin cortical patch + 0
                  actomyosin contractile ring + 5
                  cuticular plate 12
                  macropinocytic cup cytoskeleton 0
                  spectrin 6
                  terminal web 4
paths to the root