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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical actin cytoskeleton
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Accession:GO:0030864 term browser browse the term
Definition:The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.


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cortical actin cytoskeleton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN1 actinin alpha 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:49,460,390...49,565,986
Ensembl chr14:68,335,694...68,440,836 		JBrowse link
G ACTN2 actinin alpha 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:212,245,742...212,323,387
Ensembl chr 1:217,272,597...217,321,103 		JBrowse link
G ACTN3 actinin alpha 3 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429 		JBrowse link
G ACTN4 actinin alpha 4 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:35,742,758...35,825,321
Ensembl chr19:44,313,569...44,395,508 		JBrowse link
G AKAP13 A-kinase anchoring protein 13 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,076,422...64,438,109
Ensembl chr15:83,387,667...83,651,362 		JBrowse link
G CAP1 cyclase associated actin cytoskeleton regulatory protein 1 located_in ISO (PMID:15004221) MGI PMID:15004221 NCBI chr 1:39,325,715...39,358,365
Ensembl chr 1:40,651,262...40,683,777 		JBrowse link
G CDH1 cadherin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488 		JBrowse link
G CDH2 cadherin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr18:21,210,001...21,435,919
Ensembl chr18:24,812,019...25,008,325 		JBrowse link
G CFL1 cofilin 1 located_in ISO (PMID:15004221), (PMID:15548599) MGI PMID:15004221 PMID:15548599 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806 		JBrowse link
G CLDN5 claudin 5 located_in ISO (PMID:25816133) UniProt PMID:25816133 NCBI chr22:2,282,215...2,286,724
Ensembl chr22:17,958,182...17,959,093 		JBrowse link
G CORO1A coronin 1A located_in IEA Ensembl GO_REF:0000107 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G COTL1 coactosin like F-actin binding protein 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:65,231,112...65,284,079
Ensembl chr16:84,572,816...84,625,177 		JBrowse link
G CTTN cortactin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857 		JBrowse link
G DBN1 drebrin 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872 		JBrowse link
G DBNL drebrin like located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:44,753,062...44,775,717
Ensembl chr 7:44,824,608...44,845,891 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G DMD dystrophin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:23,728,650...26,338,849
Ensembl chr  X:31,282,415...33,492,733 		JBrowse link
G DSTN destrin, actin depolymerizing factor located_in ISO (PMID:15548599) MGI PMID:15548599 NCBI chr20:17,528,574...17,566,925
Ensembl chr20:17,506,262...17,545,331 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:71,342,291...71,346,033
Ensembl chr 6:74,629,688...74,633,754 		JBrowse link
G FLOT1 flotillin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559 		JBrowse link
G FLOT2 flotillin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,876,424...27,894,836
Ensembl chr17:28,385,191...28,405,585 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831 		JBrowse link
G GYS2 glycogen synthase 2 located_in ISO PMID:9003423 UniProt PMID:9003423 RGD:8553883 NCBI chr12:64,693,285...64,761,855
Ensembl chr12:67,297,131...67,365,773 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 located_in ISO (PMID:28089576) MGI PMID:28089576 NCBI chr15:69,076,025...69,190,082
Ensembl chr15:88,276,851...88,388,594 		JBrowse link
G LANCL2 LanC like glutathione S-transferase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,958,850...56,025,166
Ensembl chr 7:56,268,426...56,335,549 		JBrowse link
G LASP1 LIM and SH3 protein 1 located_in ISO PMID:10806114 UniProt PMID:10806114 RGD:8553950 NCBI chr17:18,350,002...18,401,693
Ensembl chr17:18,623,071...18,674,731 		JBrowse link
G LLGL1 LLGL scribble cell polarity complex component 1 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:32,770,511...32,789,756
Ensembl chr17:37,966,100...37,985,103 		JBrowse link
G LLGL2 LLGL scribble cell polarity complex component 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:69,474,804...69,524,797
Ensembl chr17:75,025,235...75,075,240 		JBrowse link
G MED28 mediator complex subunit 28 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:12,035,441...12,051,718
Ensembl chr 4:17,328,975...17,348,546 		JBrowse link
G MISP mitotic spindle positioning located_in IEA Ensembl GO_REF:0000107 NCBI chr19:369,238...383,633
Ensembl chr19:717,766...731,942 		JBrowse link
G MLPH melanophilin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:124,716,573...124,781,829
Ensembl chr2B:243,569,782...243,633,177 		JBrowse link
G MOBP myelin associated oligodendrocyte basic protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:39,372,102...39,450,066
Ensembl chr 3:39,688,104...39,699,486 		JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr16:54,331,300...54,338,656
Ensembl chr16:70,497,625...70,514,716 		JBrowse link
G MYADM myeloid associated differentiation marker located_in IEA Ensembl GO_REF:0000107 NCBI chr19:50,807,615...50,817,196
Ensembl chr19:59,663,790...59,664,758 		JBrowse link
G MYO1A myosin IA located_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,875,570...31,899,279
Ensembl chr12:32,130,708...32,152,335 		JBrowse link
G MYO1F myosin IF located_in ISO (PMID:17023661) MGI PMID:17023661 NCBI chr19:7,807,863...7,858,955
Ensembl chr19:8,656,082...8,705,107 		JBrowse link
G MYRIP myosin VIIA and Rab interacting protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:39,715,890...40,163,826
Ensembl chr 3:40,079,777...40,433,613 		JBrowse link
G MYZAP myocardial zonula adherens protein located_in ISO (MGI:4947500|PMID:20093627) UniProt PMID:20093627 MGI:4947500 NCBI chr15:36,560,355...36,653,881
Ensembl chr15:54,873,644...54,997,202 		JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA Ensembl GO_REF:0000107 NCBI chr22:10,648,022...10,738,167
Ensembl chr22:28,454,119...28,544,013 		JBrowse link
G PDLIM2 PDZ and LIM domain 2 located_in ISO RGD PMID:15505042 RGD:1359754 NCBI chr 8:21,828,923...21,844,483
Ensembl chr 8:18,767,142...18,783,658 		JBrowse link
G PJVK pejvakin located_in IEA Ensembl GO_REF:0000107 NCBI chr2B:65,708,635...65,725,766
Ensembl chr2B:183,413,265...183,423,224 		JBrowse link
G PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 located_in IEA Ensembl GO_REF:0000107 NCBI chr2A:43,723,791...43,852,380
Ensembl chr2A:44,570,356...44,700,272 		JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B located_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,224,007...44,240,906
Ensembl chr17:49,098,089...49,126,932 		JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:40,974,756...40,999,471
Ensembl chr12:41,848,785...41,873,252 		JBrowse link
G RDX radixin located_in ISO (MGI:5645204|PMID:21047789) UniProt PMID:21047789 MGI:5645204 RGD:10054076 NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO RGD PMID:16356937 RGD:1624121 NCBI chr12:6,475,723...6,506,443 JBrowse link
G SHROOM1 shroom family member 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:128,239,510...128,248,978
Ensembl chr 5:134,399,573...134,402,786 		JBrowse link
G SHROOM2 shroom family member 2 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:2,418,883...2,580,853
Ensembl chr  X:9,755,524...9,832,733 		JBrowse link
G SHROOM3 shroom family member 3 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:47,420,351...47,767,325
Ensembl chr 4:53,260,739...53,606,976 		JBrowse link
G SHROOM4 shroom family member 4 located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:42,673,968...42,974,947
Ensembl chr  X:50,464,824...50,687,221 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:42,224,273...42,257,184
Ensembl chr 1:43,600,733...43,634,143 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:133,969,717...134,045,301
Ensembl chr 1:137,760,942...137,835,927 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:99,674,819...99,755,973
Ensembl chr 9:128,341,739...128,422,971 		JBrowse link
G SPTB spectrin beta, erythrocytic located_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:45,329,658...45,466,597
Ensembl chr14:64,209,453...64,288,851 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:54,608,711...54,816,083
Ensembl chr2A:55,822,415...55,961,925 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:62,042,617...62,086,634
Ensembl chr11:65,365,588...65,409,207 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:37,515,420...37,621,473
Ensembl chr19:46,042,387...46,127,429 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 located_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
G UTRN utrophin ISO RGD PMID:10760950 RGD:1580541 NCBI chr 6:142,069,139...142,636,507
Ensembl chr 6:146,793,153...147,351,210 		JBrowse link
G WDR1 WD repeat domain 1 located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:4,487,054...4,516,732
Ensembl chr 4:9,805,164...9,848,032 		JBrowse link
actin cap term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 located_in ISO (PMID:21494665), (PMID:21874009) MGI PMID:21494665 PMID:21874009 NCBI chr2A:65,289,675...65,333,219
Ensembl chr2A:66,413,011...66,456,857 		JBrowse link
G CALD1 caldesmon 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:126,743,466...126,935,412
Ensembl chr 7:139,337,692...139,440,643 		JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831 		JBrowse link
G WASL WASP like actin nucleation promoting factor located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:115,675,170...115,741,498
Ensembl chr 7:128,360,495...128,385,393 		JBrowse link
actomyosin contractile ring term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANLN anillin, actin binding protein located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:37,011,518...37,075,349
Ensembl chr 7:37,243,917...37,304,137 		JBrowse link
G MAEA macrophage erythroblast attacher, E3 ubiquitin ligase located_in ISO (PMID:16510120) UniProt PMID:16510120 NCBI chr 4:1,432,848...1,485,764
Ensembl chr 4:1,315,810...1,366,448 		JBrowse link
G MYH2 myosin heavy chain 2 located_in ISO (PMID:15548599) MGI PMID:15548599 NCBI chr17:41,103,730...41,132,264
Ensembl chr17:45,851,160...45,879,666 		JBrowse link
G MYH9 myosin heavy chain 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 located_in ISO (PMID:9265651) MGI PMID:9265651 Ensembl chr15:75,533,114...75,552,365 JBrowse link
G RTKN rhotekin located_in IEA TreeGrafter GO_REF:0000118 NCBI chr2A:74,492,520...74,509,037
Ensembl chr2A:75,998,494...76,015,046 		JBrowse link
cuticular plate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALB1 calbindin 1 ISO RGD PMID:16120789 RGD:7175527 NCBI chr 8:86,747,702...86,771,995
Ensembl chr 8:88,699,532...88,723,814 		JBrowse link
G CALB2 calbindin 2 ISO RGD PMID:16120789 RGD:7175527 NCBI chr16:53,620,317...53,653,372
Ensembl chr16:71,195,770...71,227,937 		JBrowse link
G CIB2 calcium and integrin binding family member 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:57,033,782...57,060,650
Ensembl chr15:75,998,797...76,025,485 		JBrowse link
G FCHSD1 FCH and double SH3 domains 1 located_in ISO (MGI:6233193|PMID:23437151) UniProt PMID:23437151 MGI:6233193 NCBI chr 5:137,000,158...137,012,379 JBrowse link
G KNCN kinocilin located_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:45,849,905...45,854,234
Ensembl chr 1:47,203,947...47,209,516 		JBrowse link
G MYO1E myosin IE ISO RGD PMID:12486594 RGD:1298992 NCBI chr15:38,106,599...38,343,040
Ensembl chr15:56,413,570...56,649,722 		JBrowse link
G OCM oncomodulin ISO RGD PMID:16120789 RGD:7175527 NCBI chr 7:6,066,257...6,126,400 JBrowse link
G PVALB parvalbumin ISO RGD PMID:16120789 RGD:7175527 NCBI chr22:17,715,109...17,731,587
Ensembl chr22:35,551,448...35,568,316 		JBrowse link
G SNX9 sorting nexin 9 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:155,724,026...155,844,553
Ensembl chr 6:157,824,918...157,903,357 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:133,969,717...134,045,301
Ensembl chr 1:137,760,942...137,835,927 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 located_in ISO (PMID:18796539) MGI PMID:18796539 NCBI chr 9:99,674,819...99,755,973
Ensembl chr 9:128,341,739...128,422,971 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr2A:54,608,711...54,816,083
Ensembl chr2A:55,822,415...55,961,925 		JBrowse link
G TMC2 transmembrane channel like 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr20:2,667,175...2,750,058
Ensembl chr20:2,409,961...2,513,365 		JBrowse link
spectrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRKCB protein kinase C beta part_of IEA Ensembl GO_REF:0000107 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203 		JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:133,969,717...134,045,301
Ensembl chr 1:137,760,942...137,835,927 		JBrowse link
G SPTB spectrin beta, erythrocytic part_of IEA InterPro GO_REF:0000002 NCBI chr14:45,329,658...45,466,597
Ensembl chr14:64,209,453...64,288,851 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 part_of IEA InterPro GO_REF:0000002 NCBI chr2A:54,608,711...54,816,083
Ensembl chr2A:55,822,415...55,961,925 		JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 part_of IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr11:62,042,617...62,086,634
Ensembl chr11:65,365,588...65,409,207 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 part_of IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr19:37,515,420...37,621,473
Ensembl chr19:46,042,387...46,127,429 		JBrowse link
terminal web term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COBL cordon-bleu WH2 repeat protein located_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:51,652,318...51,952,256
Ensembl chr 7:51,895,807...52,097,841 		JBrowse link
G HFE homeostatic iron regulator ISO RGD PMID:16208485 RGD:1582698 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G KRT19 keratin 19 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,788,355...15,793,127
Ensembl chr17:16,006,608...16,010,782 		JBrowse link
G PLS1 plastin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:139,629,825...139,747,080
Ensembl chr 3:147,289,205...147,338,600 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17401
    cellular anatomical entity 17178
      cytoplasm 10949
        cell cortex 322
          cortical cytoskeleton 128
            cortical actin cytoskeleton 86
              actin cap 4
              actin cortical patch + 0
              actomyosin contractile ring + 6
              cuticular plate 13
              macropinocytic cup cytoskeleton 0
              spectrin 6
              terminal web 4
Path 2
Term Annotations click to browse term
  cellular_component 17401
    cellular anatomical entity 17178
      organelle 12678
        non-membrane-bounded organelle 4686
          intracellular non-membrane-bounded organelle 4686
            cytoskeleton 2175
              actin cytoskeleton 516
                cortical actin cytoskeleton 86
                  actin cap 4
                  actin cortical patch + 0
                  actomyosin contractile ring + 6
                  cuticular plate 13
                  macropinocytic cup cytoskeleton 0
                  spectrin 6
                  terminal web 4
paths to the root