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ONTOLOGY REPORT - ANNOTATIONS


Term:polarized epithelial cell differentiation
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Accession:GO:0030859 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.


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polarized epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg5 discs large MAGUK scaffold protein 5 acts_upstream_of_or_within ISO MGI:3757646 (MGI:3722974|PMID:17765678) RGD PMID:17765678 MGI:3722974 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Rab10 RAB10, member RAS oncogene family involved_in ISO
ISS
(PMID:17132146)
GO_REF:0000024
RGD
UniProt
PMID:17132146 GO_REF:0000024 NCBI chr 6:27,668,387...27,721,120
Ensembl chr 6:27,668,403...27,721,120
JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:27380321) RGD PMID:27380321 NCBI chr 7:117,105,810...117,128,802
Ensembl chr 7:117,105,810...117,128,798
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934269 (MGI:3525891|PMID:15189821) RGD PMID:15189821 MGI:3525891 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 involved_in ISS
ISO
GO_REF:0000024
(PMID:27380321)
UniProt
RGD
PMID:27380321 GO_REF:0000024 NCBI chr19:52,733,161...52,750,307
Ensembl chr19:52,733,161...52,750,307
JBrowse link
establishment of epithelial cell apical/basal polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 involved_in ISO (PMID:26715742), (PMID:27802168)
(MGI:5754645|PMID:26715742)
RGD PMID:26715742 PMID:27802168 MGI:5754645 NCBI chr12:2,133,935...2,157,403
Ensembl chr12:2,134,022...2,157,403
JBrowse link
G Cdc42 cell division cycle 42 involved_in ISS
ISO
GO_REF:0000024
(PMID:22891260)
UniProt
RGD
PMID:22891260 GO_REF:0000024 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Ezr ezrin NOT|involved_in ISO (PMID:22797597), (PMID:24862762) RGD PMID:22797597 PMID:24862762 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:1347479 (MGI:3617131|PMID:16439479) RGD PMID:16439479 MGI:3617131 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086
JBrowse link
G Ift20 intraflagellar transport 20 acts_upstream_of_or_within ISO MGI:3817268 (MGI:5615303|PMID:25605782) RGD PMID:25605782 MGI:5615303 NCBI chr10:65,805,808...65,811,353
Ensembl chr10:65,805,860...65,811,351
JBrowse link
G Lama1 laminin subunit alpha 1 acts_upstream_of_or_within ISO MGI:3530455 (MGI:3529401|PMID:15668394) RGD PMID:15668394 MGI:3529401 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Msn moesin involved_in ISO
IEA
(PMID:24862762)
GO_REF:0000107
RGD
Ensembl
PMID:24862762 GO_REF:0000107 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Myo9a myosin IXA involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:22891260)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:22891260 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:64,573,248...64,777,607
Ensembl chr 8:64,573,358...64,777,543
JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO
ISS
(PMID:22891260)
GO_REF:0000024
RGD
UniProt
PMID:22891260 GO_REF:0000024 NCBI chr  X:68,185,865...68,579,518
Ensembl chr  X:68,189,161...68,563,137
JBrowse link
G Ptk7 protein tyrosine kinase 7 acts_upstream_of_or_within ISO MGI:3046905 (MGI:3046397|PMID:15229603) RGD PMID:15229603 MGI:3046397 NCBI chr 9:16,662,588...16,729,888
Ensembl chr 9:16,702,460...16,729,030
JBrowse link
G Rap2a RAP2A, member of RAS oncogene family NOT|involved_in ISO (PMID:22797597) RGD PMID:22797597 NCBI chr15:105,851,543...105,852,033
Ensembl chr15:105,851,542...105,878,666
JBrowse link
G Rhoa ras homolog family member A involved_in ISO
ISS
(PMID:22891260)
GO_REF:0000024
RGD
UniProt
PMID:22891260 GO_REF:0000024 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Sh3bp1 SH3-domain binding protein 1 involved_in ISO
ISS
(PMID:22891260)
GO_REF:0000024
RGD
UniProt
PMID:22891260 GO_REF:0000024 NCBI chr 7:120,125,747...120,138,148
Ensembl chr 7:120,125,633...120,138,196
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 involved_in ISO (PMID:24862762) RGD PMID:24862762 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Spag6l sperm associated antigen 6-like acts_upstream_of_or_within ISO MGI:2662475 (MGI:5644628|PMID:25333478) RGD PMID:25333478 MGI:5644628 NCBI chr11:88,424,493...88,517,910
Ensembl chr11:88,424,414...88,508,601
JBrowse link
G Syne4 spectrin repeat containing nuclear envelope family member 4 involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:4441244|PMID:19164528)
PMID:21873635
UniProt
RGD
PMID:19164528, PMID:21873635 GO_REF:0000024 MGI:4441244, RGD:13792537 NCBI chr 1:88,772,729...88,777,044
Ensembl chr 1:88,772,904...88,776,999
Ensembl chr 1:88,772,904...88,776,999
JBrowse link
G Tcf15 transcription factor 15 acts_upstream_of_or_within ISO MGI:1929775 (MGI:5522599|PMID:24038871) RGD PMID:24038871 MGI:5522599 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
G Ttc8 tetratricopeptide repeat domain 8 acts_upstream_of_or_within ISO MGI:5140723 (MGI:5615303|PMID:25605782) RGD PMID:25605782 MGI:5615303 NCBI chr 6:122,920,308...122,974,525
Ensembl chr 6:122,920,317...122,974,522
JBrowse link
G Wnt5a Wnt family member 5A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:101948 (MGI:5634837|PMID:25813538)
Ensembl
RGD
PMID:25813538 GO_REF:0000107 MGI:5634837 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fat1 FAT atypical cadherin 1 involved_in ISO MGI:2662293 (MGI:5766588|PMID:26114487) RGD PMID:26114487 MGI:5766588 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921
JBrowse link
positive regulation of polarized epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahi1 Abelson helper integration site 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5306539|PMID:21959375)
UniProt
RGD
PMID:21959375 GO_REF:0000024 MGI:5306539 NCBI chr 1:16,478,127...16,601,769
Ensembl chr 1:16,478,127...16,601,769
JBrowse link
G Numb NUMB, endocytic adaptor protein acts_upstream_of_or_within ISO (MGI:4950299|PMID:21385765) RGD PMID:21385765 MGI:4950299 NCBI chr 6:107,279,917...107,325,345
Ensembl chr 6:107,279,920...107,325,345
JBrowse link
regulation of polarized epithelial cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ajap1 adherens junctions associated protein 1 involved_in ISO
IEA
(PMID:14595118)
GO_REF:0000107
RGD
Ensembl
PMID:14595118 GO_REF:0000107 NCBI chr 5:170,615,885...170,679,315
Ensembl chr 5:170,615,886...170,679,315
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      cellular developmental process 4461
        cell differentiation 4365
          epithelial cell differentiation 712
            polarized epithelial cell differentiation 28
              establishment of epithelial cell apical/basal polarity + 20
              negative regulation of polarized epithelial cell differentiation 0
              positive regulation of polarized epithelial cell differentiation 2
              regulation of polarized epithelial cell differentiation + 3
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        tissue development 2070
          epithelium development 1273
            morphogenesis of an epithelium 591
              morphogenesis of a polarized epithelium 87
                polarized epithelial cell differentiation 28
                  establishment of epithelial cell apical/basal polarity + 20
                  negative regulation of polarized epithelial cell differentiation 0
                  positive regulation of polarized epithelial cell differentiation 2
                  regulation of polarized epithelial cell differentiation + 3
paths to the root