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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of actin filament polymerization
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Accession:GO:0030838 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of actin polymerization.
Comment:Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin depolymerization ; GO:0030836').
Synonyms:exact_synonym: positive regulation of actin polymerization;   up regulation of actin filament polymerization;   upregulation of actin filament polymerization
 narrow_synonym: activation of actin filament polymerization;   stimulation of actin filament polymerization
 broad_synonym: positive regulation of actin polymerization and/or depolymerization


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positive regulation of actin filament polymerization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr3 actin related protein 3 JBrowse link 13 41,695,520 41,738,622 RGD:2306202
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:1624291
RGD:1600115
G Arf6 ADP-ribosylation factor 6 JBrowse link 6 91,697,109 91,698,257 RGD:1624291
G Arpc2 actin related protein 2/3 complex, subunit 2 JBrowse link 9 81,518,163 81,548,871 RGD:1624291
G Bag4 BAG cochaperone 4 JBrowse link 16 71,057,709 71,075,874 RGD:1624291
RGD:1600115
G Baiap2 BAR/IMD domain containing adaptor protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:13792537
G Baiap2l1 BAI1-associated protein 2-like 1 JBrowse link 12 12,226,967 12,321,172 RGD:1624291
RGD:13792537
RGD:1600115
G Baiap2l2 BAI1-associated protein 2-like 2 JBrowse link 7 120,492,366 120,518,803 RGD:13792537
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
G Carmil1 capping protein regulator and myosin 1 linker 1 JBrowse link 17 43,050,282 43,339,403 RGD:1624291
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:1624291
G Ccl21 C-C motif chemokine ligand 21 JBrowse link 5 58,197,678 58,198,782 RGD:1624291
G Ccl24 C-C motif chemokine ligand 24 JBrowse link 12 24,131,529 24,152,626 RGD:1624291
G Ccl26 C-C motif chemokine ligand 26 JBrowse link 12 24,157,182 24,161,870 RGD:1624291
G Cdc42ep1 CDC42 effector protein 1 JBrowse link 7 120,063,256 120,071,154 RGD:13792537
G Cdc42ep2 CDC42 effector protein 2 JBrowse link 1 221,272,349 221,281,252 RGD:1624291
RGD:13792537
G Cdc42ep3 CDC42 effector protein 3 JBrowse link 6 1,922,500 1,942,972 RGD:13792537
G Cdc42ep4 CDC42 effector protein 4 JBrowse link 10 102,244,680 102,269,272 RGD:13792537
G Cdc42ep5 CDC42 effector protein 5 JBrowse link 1 73,717,207 73,719,600 RGD:1624291
RGD:13792537
G Cracd capping protein inhibiting regulator of actin dynamics JBrowse link 14 33,649,989 33,783,794 RGD:1624291
G Csf3 colony stimulating factor 3 JBrowse link 10 86,616,785 86,619,160 RGD:1624291
G Cttn cortactin JBrowse link 1
1
217,602,698
215,255,385
217,638,196
215,290,882
RGD:10047281
RGD:1624291
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
RGD:1600115
G Evl Enah/Vasp-like JBrowse link 6 132,470,283 132,590,242 RGD:1624291
RGD:13792537
G Fchsd1 FCH and double SH3 domains 1 JBrowse link 18 31,096,815 31,109,077 RGD:1624291
G Fchsd2 FCH and double SH3 domains 2 JBrowse link 1 166,140,025 166,395,915 RGD:1624291
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:1600115
RGD:1624291
G Fmn1 formin 1 JBrowse link 3 104,783,093 105,170,761 RGD:1624291
G Grb2 growth factor receptor bound protein 2 JBrowse link 10 104,193,953 104,263,071 RGD:1624291
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:7240703
G Kirrel1 kirre like nephrin family adhesion molecule 1 JBrowse link 2 186,420,743 186,515,209 RGD:1624291
G Lmod1 leiomodin 1 JBrowse link 13 52,147,099 52,189,835 RGD:1624291
RGD:1600115
G Lmod2 leiomodin 2 JBrowse link 4 51,553,439 51,561,135 RGD:1624291
RGD:1600115
G LOC100909840 profilin-2-like JBrowse link 2 148,044,714 148,050,464 RGD:1600115
G LOC691418 hypothetical protein LOC691418 JBrowse link 3 110,980,265 110,983,932 RGD:13792537
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:1624291
G Mlst8 MTOR associated protein, LST8 homolog JBrowse link 10 13,839,250 13,845,001 RGD:1624291
RGD:1600115
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
G Myo1c myosin 1C JBrowse link 10 63,803,311 63,819,614 RGD:11073622
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Nckap1 NCK-associated protein 1 JBrowse link 3 67,725,180 67,804,680 RGD:1624291
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G Nphs1 NPHS1 adhesion molecule, nephrin JBrowse link 1 88,922,346 88,950,560 RGD:1624291
RGD:1600115
G Pfn1 profilin 1 JBrowse link 10 57,273,003 57,275,708 RGD:1624291
G Pfn2 profilin 2 JBrowse link 2 147,953,858 147,959,692 RGD:1624291
RGD:1600115
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
RGD:1600115
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:1624291
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1642965
G Rictor RPTOR independent companion of MTOR, complex 2 JBrowse link 2 56,013,898 56,105,818 RGD:1624291
G Snx9 sorting nexin 9 JBrowse link 1 46,780,142 46,826,250 RGD:1624291
G Tenm1 teneurin transmembrane protein 1 JBrowse link X
X
129,034,755
128,923,951
129,336,023
128,951,520
RGD:1624291
G Vasp vasodilator-stimulated phosphoprotein JBrowse link 1 80,170,608 80,185,882 RGD:1624291
RGD:13792537
'de novo' actin filament nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jmy junction mediating and regulatory protein, p53 cofactor JBrowse link 2 23,026,506 23,097,702 RGD:1624291
RGD:13792537
actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Evl Enah/Vasp-like JBrowse link 6 132,470,283 132,590,242 RGD:1600115
G Fmn1 formin 1 JBrowse link 3 104,783,093 105,170,761 RGD:1600115
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:1600115
G Lmod1 leiomodin 1 JBrowse link 13 52,147,099 52,189,835 RGD:1624291
RGD:1600115
G Lmod2 leiomodin 2 JBrowse link 4 51,553,439 51,561,135 RGD:1600115
RGD:1624291
G Lmod3 leiomodin 3 JBrowse link 4 129,604,378 129,619,136 RGD:1624291
G Spire1 spire-type actin nucleation factor 1 JBrowse link 18 63,226,557 63,357,420 RGD:1600115
G Spire2 spire-type actin nucleation factor 2 JBrowse link 19 56,136,904 56,175,500 RGD:1600115
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1600115
Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Actr2 actin related protein 2 JBrowse link 14 104,338,486 104,375,840 RGD:1600115
RGD:13792537
RGD:1624291
G Actr3 actin related protein 3 JBrowse link 13 41,695,520 41,738,622 RGD:1600115
RGD:13792537
RGD:1624291
G Actr3b actin related protein 3B JBrowse link 4 5,644,287 5,672,708 RGD:1600115
G Arpc1a actin related protein 2/3 complex, subunit 1A JBrowse link 12 11,272,609 11,294,084 RGD:1600115
RGD:13792537
G Arpc1b actin related protein 2/3 complex, subunit 1B JBrowse link 12 11,252,300 11,265,849 RGD:1624291
RGD:13792537
G Arpc2 actin related protein 2/3 complex, subunit 2 JBrowse link 9 81,518,163 81,548,871 RGD:1624291
RGD:13792537
RGD:1600115
G Arpc3 actin related protein 2/3 complex, subunit 3 JBrowse link 12 39,653,951 39,667,817 RGD:1624291
RGD:13792537
G Arpc4 actin related protein 2/3 complex, subunit 4 JBrowse link 4 145,330,457 145,340,985 RGD:1624291
G Arpc5 actin related protein 2/3 complex, subunit 5 JBrowse link 13 70,174,970 70,183,879 RGD:1624291
RGD:13792537
RGD:1600115
G Arpc5l actin related protein 2/3 complex, subunit 5-like JBrowse link 3 23,301,455 23,309,077 RGD:13792537
G Arpc5l-ps1 actin related protein 2/3 complex, subunit 5-like, pseudogene 1 JBrowse link 9 49,794,998 49,795,995 RGD:13792537
G Iqgap2 IQ motif containing GTPase activating protein 2 JBrowse link 2 26,161,628 26,439,067 RGD:1624291
G Jmy junction mediating and regulatory protein, p53 cofactor JBrowse link 2 23,026,506 23,097,702 RGD:1624291
RGD:13792537
G Magel2 MAGE family member L2 JBrowse link 1 123,015,404 123,019,945 RGD:1624291
G Trim27 tripartite motif-containing 27 JBrowse link 17 45,613,863 45,626,212 RGD:1624291
G Washc1 WASH complex subunit 1 JBrowse link 9 113,918,914 113,936,861 RGD:1600115
RGD:1624291
G Whamm WASP homolog associated with actin, golgi membranes and microtubules JBrowse link 1 143,401,986 143,430,356 RGD:13792537
negative regulation of actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arpin actin-related protein 2/3 complex inhibitor JBrowse link 1 141,664,790 141,672,789 RGD:1624291
RGD:13792537
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:1624291
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coro1b coronin 1B JBrowse link 1 219,397,827 219,403,253 RGD:1624291
RGD:1600115
G Ctnna2 catenin alpha 2 JBrowse link 4 107,880,611 109,042,724 RGD:1624291
G Gmfb glia maturation factor, beta JBrowse link 15 23,597,846 23,611,541 RGD:1600115
RGD:13792537
G Gmfg glia maturation factor, gamma JBrowse link 1 85,312,473 85,322,860 RGD:1624291
RGD:13792537
RGD:1600115
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1624291
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:8554748
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Carmil1 capping protein regulator and myosin 1 linker 1 JBrowse link 17 43,050,282 43,339,403 RGD:1624291
G Carmil2 capping protein regulator and myosin 1 linker 2 JBrowse link 19 37,652,383 37,665,333 RGD:1624291
G Cracd capping protein inhibiting regulator of actin dynamics JBrowse link 14 33,649,989 33,783,794 RGD:1624291
RGD:13792537
G Washc2c WASH complex subunit 2C JBrowse link 4 148,139,512 148,197,363 RGD:1624291
positive regulation of actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fmn1 formin 1 JBrowse link 3 104,783,093 105,170,761 RGD:1624291
RGD:1600115
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:1624291
G Magel2 MAGE family member L2 JBrowse link 1 123,015,404 123,019,945 RGD:1624291
G Scin scinderin JBrowse link 6 59,975,375 60,055,075 RGD:1624291
G Trim27 tripartite motif-containing 27 JBrowse link 17 45,613,863 45,626,212 RGD:1624291
G Whamm WASP homolog associated with actin, golgi membranes and microtubules JBrowse link 1 143,401,986 143,430,356 RGD:1624291
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi2 abl-interactor 2 JBrowse link 9 67,234,612 67,284,504 RGD:1624291
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex JBrowse link 4 145,559,206 145,574,438 RGD:1624291
G Cyfip1 cytoplasmic FMR1 interacting protein 1 JBrowse link 1 114,258,773 114,347,138 RGD:1624291
G Fchsd2 FCH and double SH3 domains 2 JBrowse link 1 166,140,025 166,395,915 RGD:1624291
G Nckap1 NCK-associated protein 1 JBrowse link 3 67,725,180 67,804,680 RGD:1600115
RGD:1624291
G RGD1561552 similar to WASP family 1 JBrowse link X 79,064,200 79,066,932 RGD:13792537
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:1600115
G Wasf1 WASP family member 1 JBrowse link 20 48,456,191 48,503,768 RGD:1624291
RGD:13792537
G Wasf2 WASP family member 2 JBrowse link 5 151,319,382 151,385,051 RGD:13792537
G Wasf3 WASP family member 3 JBrowse link 12 10,297,896 10,391,014 RGD:13792537
G Wasl WASP like actin nucleation promoting factor JBrowse link 4 51,677,722 51,726,212 RGD:1600115
regulation of actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1624291
G Washc5 WASH complex subunit 5 JBrowse link 7 99,625,379 99,677,237 RGD:1624291
regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1ar adaptor-related protein complex 1 associated regulatory protein JBrowse link 2 232,146,418 232,178,813 RGD:1624291
G Arf1 ADP-ribosylation factor 1 JBrowse link 10 45,562,700 45,579,214 RGD:8553918
G Arfip1 ADP-ribosylation factor interacting protein 1 JBrowse link 2 183,503,250 183,582,798 RGD:13792537
G Arfip2 ADP-ribosylation factor interacting protein 2 JBrowse link 1 170,464,995 170,471,138 RGD:13792537
G Coro1b coronin 1B JBrowse link 1 219,397,827 219,403,253 RGD:10047170
G Pick1 protein interacting with PRKCA 1 JBrowse link 7 120,465,472 120,484,824 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      positive regulation of cellular process 6100
        positive regulation of cellular component organization 1313
          positive regulation of supramolecular fiber organization 214
            positive regulation of actin filament polymerization 100
              actin nucleation + 51
              negative regulation of barbed-end actin filament capping 4
              positive regulation of actin filament polymerization involved in acrosome reaction 0
              positive regulation of actin filament polymerization involved in sperm capacitation 0
              positive regulation of actin nucleation + 17
Path 2
Term Annotations click to browse term
  biological_process 19678
    cellular process 18452
      cellular component organization or biogenesis 6666
        cellular component organization 6426
          regulation of cellular component organization 2610
            regulation of organelle organization 1388
              regulation of cytoskeleton organization 591
                regulation of actin cytoskeleton organization 375
                  regulation of actin filament organization 284
                    regulation of actin polymerization or depolymerization 199
                      regulation of actin filament polymerization 181
                        positive regulation of actin filament polymerization 100
                          actin nucleation + 51
                          negative regulation of barbed-end actin filament capping 4
                          positive regulation of actin filament polymerization involved in acrosome reaction 0
                          positive regulation of actin filament polymerization involved in sperm capacitation 0
                          positive regulation of actin nucleation + 17
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.