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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of actin filament polymerization
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Accession:GO:0030838 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of actin polymerization.
Comment:Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin depolymerization ; GO:0030836').
Synonyms:exact_synonym: positive regulation of actin polymerization;   up regulation of actin filament polymerization;   upregulation of actin filament polymerization
 narrow_synonym: activation of actin filament polymerization;   stimulation of actin filament polymerization
 broad_synonym: positive regulation of actin polymerization and/or depolymerization



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positive regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actr3 actin related protein 3 IMP RGD PMID:18256280 RGD:2306202 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISS
ISO
GO_REF:0000024
(MGI:5508294|PMID:11278875)
UniProt
RGD
PMID:11278875 GO_REF:0000024 MGI:5508294 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Arf6 ADP-ribosylation factor 6 involved_in ISO (PMID:10036235) RGD PMID:10036235 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3818245|PMID:18836449)
GO_REF:0000107
RGD
Ensembl
PMID:18836449 GO_REF:0000107 MGI:3818245 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
JBrowse link
G Bag4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) RGD PMID:21712384 MGI:5292318 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:21098279)
UniProt
RGD
PMID:21098279 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
JBrowse link
G Baiap2l2 BAR/IMD domain containing adaptor protein 2 like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:110,824,370...110,850,702
Ensembl chr 7:110,824,375...110,850,702
JBrowse link
G Bin1 bridging integrator 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:5583915|PMID:24836577)
Ensembl
RGD
PMID:24836577 GO_REF:0000107 MGI:5583915 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 involved_in ISO (PMID:19525930) RGD PMID:19525930 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:11242036) RGD PMID:11242036 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 involved_in ISO (PMID:19525930) RGD PMID:19525930 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 involved_in ISO (PMID:19525930) RGD PMID:19525930 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200
JBrowse link
G Cdc42ep2 CDC42 effector protein 2 involved_in ISO
IBA
(PMID:11035016)
PMID:21873635
RGD PMID:11035016 PMID:21873635 RGD:13792537 NCBI chr 1:203,202,000...203,210,891
Ensembl chr 1:203,201,873...203,210,897
JBrowse link
G Cdc42ep3 CDC42 effector protein 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
JBrowse link
G Cdc42ep4 CDC42 effector protein 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 involved_in ISO (PMID:11035016) RGD PMID:11035016 NCBI chr 1:70,035,921...70,038,990 JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) RGD PMID:30361697 NCBI chr14:31,284,066...31,520,103
Ensembl chr14:31,284,184...31,522,431
JBrowse link
G Csf3 colony stimulating factor 3 involved_in ISO (PMID:23001182) RGD PMID:23001182 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Cttn cortactin involved_in ISO
IEA
IMP
UniProtKB:P07737 (PMID:24700464)
GO_REF:0000107
PMID:18768925
RGD
Ensembl
PMID:24700464 PMID:18768925 GO_REF:0000107, RGD:10047281 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3528803|PMID:15699074)
Ensembl
RGD
PMID:15699074 GO_REF:0000107 MGI:3528803 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Evl Enah/Vasp-like involved_in IBA
ISO
PMID:21873635
(MGI:5545940|PMID:23153535)
RGD PMID:23153535 PMID:21873635 MGI:5545940, RGD:13792537 NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344
JBrowse link
G Fchsd1 FCH and double SH3 domains 1 involved_in ISO (MGI:6233193|PMID:23437151) RGD PMID:23437151 MGI:6233193 NCBI chr18:29,793,899...29,804,533
Ensembl chr18:29,793,899...29,804,466
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 involved_in ISO (MGI:6233193|PMID:23437151) RGD PMID:23437151 MGI:6233193 NCBI chr 1:155,444,471...155,685,539
Ensembl chr 1:155,444,460...155,685,539
JBrowse link
G Fer FER tyrosine kinase involved_in ISO
ISS
(PMID:19738202)
GO_REF:0000024
RGD
UniProt
PMID:19738202 GO_REF:0000024 NCBI chr 9:103,520,452...103,827,364
Ensembl chr 9:103,520,493...103,821,451
JBrowse link
G Fmn1 formin 1 acts_upstream_of_or_within ISO (MGI:3027450|PMID:14647292) RGD PMID:14647292 MGI:3027450 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220
JBrowse link
G Grb2 growth factor receptor bound protein 2 acts_upstream_of_or_within ISO MGI:1891396 (MGI:3768467|PMID:17923684) RGD PMID:17923684 MGI:3768467 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Kirrel1 kirre like nephrin family adhesion molecule 1 acts_upstream_of_or_within ISO MGI:109601|MGI:1859637|MGI:95805 (MGI:3768467|PMID:17923684) RGD PMID:17923684 MGI:3768467 NCBI chr 2:172,521,644...172,615,057
Ensembl chr 2:172,525,245...172,615,299
JBrowse link
G Lmod1 leiomodin 1 involved_in ISO
ISS
(PMID:26370058)
GO_REF:0000024
RGD
UniProt
PMID:26370058 GO_REF:0000024 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900
JBrowse link
G Lmod2 leiomodin 2 involved_in ISO
IEA
ISS
(PMID:26370058)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26370058 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120
JBrowse link
G LOC691418 hypothetical protein LOC691418 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,163,898...106,167,404
Ensembl chr 3:106,157,382...106,167,831
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO MGI:2676654 (MGI:2674169|PMID:12941696), (MGI:5608927|PMID:25224220) RGD PMID:12941696 PMID:25224220 MGI:2674169 MGI:5608927 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3510095|PMID:15467718)
Ensembl
RGD
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr10:13,498,377...13,504,128
Ensembl chr10:13,498,388...13,504,128
JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) RGD PMID:15467718 MGI:3510095 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myo1c myosin 1C IMP RGD PMID:22918957 RGD:11073622 NCBI chr10:60,498,374...60,520,752
Ensembl chr10:60,498,280...60,520,752
JBrowse link
G Nck1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12110186)
MGI:1859637|MGI:1891396|MGI:95805 (MGI:3768467|PMID:17923684)
RGD PMID:12110186 PMID:17923684 MGI:3768467 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO (PMID:12110186) RGD PMID:12110186 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307
JBrowse link
G Nckap1 NCK-associated protein 1 involved_in ISO (MGI:5897521|PMID:27927633) RGD PMID:27927633 MGI:5897521 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(PMID:16417406), (PMID:32647003)
(MGI:3818191|PMID:19015308)
UniProt
RGD
PMID:16417406 PMID:19015308 PMID:32647003 GO_REF:0000024 MGI:3818191 NCBI chr 7:134,577,443...134,622,934
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:109601|MGI:1891396|MGI:95805 (MGI:3768467|PMID:17923684)
Ensembl
RGD
PMID:17923684 GO_REF:0000107 MGI:3768467 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
JBrowse link
G Pfn1 profilin 1 involved_in ISO UniProtKB:P35080 (PMID:23153535) RGD PMID:23153535 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631
JBrowse link
G Pfn2 profilin 2 involved_in
acts_upstream_of_or_within
ISO
IEA
UniProtKB:P07737 (PMID:23153535)
GO_REF:0000107
MGI:3715145 (MGI:3714870|PMID:17541406)
RGD
Ensembl
PMID:17541406 PMID:23153535 GO_REF:0000107 MGI:3714870 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
JBrowse link
G Prkce protein kinase C, epsilon involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5306325|PMID:11746497)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:11746497 GO_REF:0000024 GO_REF:0000107 MGI:5306325 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO
GO_REF:0000024
(PMID:18765415)
UniProt
RGD
PMID:18765415 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (MGI:5291858|PMID:21892172) RGD PMID:21892172 MGI:5291858 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rac1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (MGI:2668778|PMID:12853475) RGD PMID:12853475 MGI:2668778 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17369454 RGD:1642965 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) RGD PMID:15467718 MGI:3510095 NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
JBrowse link
G Snx9 sorting nexin 9 involved_in ISO (MGI:6233193|PMID:23437151) RGD PMID:23437151 MGI:6233193 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036
JBrowse link
G Tenm1 teneurin transmembrane protein 1 involved_in ISO (MGI:5465054|PMID:22698694) RGD PMID:22698694 MGI:5465054 NCBI chr  X:121,400,466...122,289,877
Ensembl chr  X:121,403,649...122,290,207
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein involved_in IBA
ISO
PMID:21873635
(PMID:23153535)
RGD PMID:23153535 PMID:21873635 RGD:13792537 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA
(PMID:30361697)
PMID:21873635
RGD PMID:30361697 PMID:21873635 RGD:13792537 NCBI chr14:31,284,066...31,520,103
Ensembl chr14:31,284,184...31,522,431
JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18877
    cellular process 17586
      positive regulation of cellular process 6054
        positive regulation of cellular component organization 1231
          positive regulation of supramolecular fiber organization 192
            positive regulation of actin filament polymerization 56
              negative regulation of barbed-end actin filament capping 4
              positive regulation of actin filament polymerization involved in acrosome reaction 0
              positive regulation of actin filament polymerization involved in sperm capacitation 0
Path 2
Term Annotations click to browse term
  biological_process 18877
    cellular process 17586
      cellular component organization or biogenesis 6563
        cellular component organization 6330
          organelle organization 3543
            cytoskeleton organization 1504
              actin cytoskeleton organization 755
                actin filament organization 471
                  actin polymerization or depolymerization 210
                    actin filament polymerization 177
                      regulation of actin filament polymerization 153
                        positive regulation of actin filament polymerization 56
                          negative regulation of barbed-end actin filament capping 4
                          positive regulation of actin filament polymerization involved in acrosome reaction 0
                          positive regulation of actin filament polymerization involved in sperm capacitation 0
paths to the root