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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of actin filament depolymerization
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Accession:GO:0030836 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of actin depolymerization.
Comment:Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838').
Synonyms:exact_synonym: actin filament destabilization;   positive regulation of actin depolymerization;   up regulation of actin filament depolymerization;   upregulation of actin filament depolymerization
 narrow_synonym: activation of actin filament depolymerization;   stimulation of actin filament depolymerization
 broad_synonym: positive regulation of actin polymerization and/or depolymerization
 alt_id: GO:0030045

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positive regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFL1 cofilin 1 acts_upstream_of_or_within
involved_in 		ISO (PMID:15548599)
(PMID:23921380) 		MGI
CACAO		 PMID:15548599 PMID:23921380 NCBI chr 1:8,408,560...8,410,564 JBrowse link
G CFL2 cofilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:11,541,226...11,545,690
Ensembl chr24:11,543,638...11,544,335 		JBrowse link
G DSTN destrin, actin depolymerizing factor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:46,636,111...46,672,771
Ensembl chr 2:46,635,954...46,673,165 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,095,446...71,109,832
Ensembl chr 4:71,095,500...71,110,005 		JBrowse link
G LOC103223283 chronophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:20,340,535...20,357,426
Ensembl chr19:20,360,108...20,368,247
Ensembl chr19:20,360,108...20,368,247 		JBrowse link
G PLEK pleckstrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:38,689,387...38,769,090
Ensembl chr14:38,689,393...38,745,893 		JBrowse link
G SEMA5A semaphorin 5A involved_in ISO (PMID:19850054) UniProt PMID:19850054 NCBI chr 4:8,598,680...9,095,346
Ensembl chr 4:8,600,959...9,095,423 		JBrowse link
G VIL1 villin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:104,311,048...104,350,846
Ensembl chr10:104,320,074...104,347,289 		JBrowse link
G WDR1 WD repeat domain 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:39,929,749...39,973,892
Ensembl chr27:39,929,787...39,974,012 		JBrowse link
actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN2 actinin alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:73,827,900...73,904,516
Ensembl chr25:73,827,874...73,905,146 		JBrowse link
barbed-end actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,637,416...46,979,061
Ensembl chr17:46,635,199...46,978,932 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,637,416...46,979,061
Ensembl chr17:46,635,199...46,978,932 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:59,787,069...59,801,615
Ensembl chr 5:59,787,120...59,801,122 		JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:12,293,366...12,570,793
Ensembl chr 7:12,296,214...12,325,965 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19706
    cellular process 19211
      positive regulation of cellular process 6353
        positive regulation of cellular component organization 1310
          positive regulation of supramolecular fiber organization 187
            positive regulation of actin filament depolymerization 13
              actin filament uncapping + 2
              negative regulation of barbed-end actin filament capping 3
Path 2
Term Annotations click to browse term
  biological_process 19706
    cellular process 19211
      cellular component organization or biogenesis 8786
        cellular component organization 8574
          organelle organization 3611
            cytoskeleton organization 1531
              actin cytoskeleton organization 730
                actin filament organization 464
                  actin polymerization or depolymerization 198
                    regulation of actin polymerization or depolymerization 160
                      regulation of actin filament depolymerization 56
                        positive regulation of actin filament depolymerization 13
                          actin filament uncapping + 2
                          negative regulation of barbed-end actin filament capping 3
paths to the root