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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of actin filament depolymerization
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Accession:GO:0030835 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.
Comment:Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin polymerization ; GO:0030837').
Synonyms:exact_synonym: actin filament stabilization;   down regulation of actin filament depolymerization;   downregulation of actin filament depolymerization;   negative regulation of actin depolymerization
 narrow_synonym: inhibition of actin filament depolymerization
 broad_synonym: negative regulation of actin polymerization and/or depolymerization
 alt_id: GO:0030044


show annotations for term's descendants           Sort by:
negative regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in ISO
ISS		 (PMID:12566430)
GO_REF:0000024		 RGD
UniProt		 PMID:12566430 GO_REF:0000024 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO
IEA		 (PMID:30568254)
GO_REF:0000107		 RGD
Ensembl		 PMID:30568254 GO_REF:0000107 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Plekhh2 pleckstrin homology, MyTH4 and FERM domain containing H2 involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:22832517)		 GO_Central
Ensembl
RGD		 PMID:22832517 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:10,032,837...10,132,081
Ensembl chr 6:10,032,660...10,140,794 		JBrowse link
G Shroom2 shroom family member 2 acts_upstream_of_or_within ISO (PMID:17666436) RGD PMID:17666436 NCBI chr  X:25,308,163...25,480,194
Ensembl chr  X:21,812,469...21,984,153 		JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO
IEA		 (PMID:21703590)
GO_REF:0000107		 RGD
Ensembl		 PMID:21703590 GO_REF:0000107 NCBI chr20:13,337,399...13,443,080
Ensembl chr20:13,339,692...13,443,665 		JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 involved_in ISO
IEA		 (PMID:23921380)
GO_REF:0000107		 RGD
Ensembl		 PMID:23921380 GO_REF:0000107 NCBI chr 1:164,267,588...164,328,796
Ensembl chr 1:164,267,609...164,328,794 		JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik similar to RIKEN cDNA 4933400A11 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr  X:24,389,645...24,393,849 JBrowse link
G Avil advillin involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Capg capping actin protein, gelsolin like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:192,319,702...192,364,480 		JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864 		JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:172,929,273...172,930,486
Ensembl chr 4:172,928,887...172,932,535 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Gsn gelsolin involved_in ISO
IEA		 (PMID:19666531)
GO_REF:0000107
GO_REF:0000043
(PMID:23325791)		 RGD
Ensembl
UniProt		 PMID:19666531 PMID:23325791 GO_REF:0000043 GO_REF:0000107 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Myh9 myosin, heavy chain 9 NOT|involved_in ISO (PMID:23325791) RGD PMID:23325791 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Scin scinderin involved_in ISO
IEA		 (PMID:19666531)
GO_REF:0000043		 RGD
UniProt		 PMID:19666531 GO_REF:0000043 NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:57,109,403...57,188,242 		JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:88,735,833...88,811,697
Ensembl chr13:86,203,504...86,279,371 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046 		JBrowse link
G Sptb spectrin, beta, erythrocytic involved_in IEA GO_REF:0000104
GO_REF:0000043		 UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 6:95,310,342...95,437,221
Ensembl chr 6:95,310,326...95,437,118 		JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 involved_in IEA GO_REF:0000104
GO_REF:0000043		 UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr14:108,042,629...108,217,884
Ensembl chr14:103,842,684...104,008,507 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in IEA GO_REF:0000043
GO_REF:0000104		 UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:211,432,373...211,473,016
Ensembl chr 1:202,002,970...202,044,283 		JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 involved_in IEA GO_REF:0000104
GO_REF:0000043		 UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228 		JBrowse link
G Tpm1 tropomyosin 1 IDA RGD PMID:15779917 RGD:1600523 NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Tpm1_v7 tropomyosin 1, variant 7 IDA RGD PMID:15779917 RGD:1600523
G Vil1 villin 1 involved_in ISO
IEA		 (PMID:16921170), (PMID:17182858), (PMID:19808673)
GO_REF:0000043
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:16921170 PMID:17182858 PMID:19808673 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
G Vill villin-like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:118,776,718...118,794,983
Ensembl chr 8:118,776,742...118,794,983 		JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik similar to RIKEN cDNA 4933400A11 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002
GO_REF:0000104		 GO_Central
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 Ensembl chr  X:24,389,645...24,393,849 JBrowse link
G Add1 adducin 1 involved_in ISO
IBA		 (PMID:8626479)
GO_REF:0000033		 RGD
GO_Central		 PMID:8626479 GO_REF:0000033 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Add2 adducin 2 involved_in ISO
IBA
IEA		 (PMID:8626479)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8626479 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505 		JBrowse link
G Add3 adducin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Avil advillin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:64,711,294...64,729,436
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Capg capping actin protein, gelsolin like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000104
GO_REF:0000002
(PMID:17656356)
GO_REF:0000033		 UniProt
InterPro
RGD
GO_Central		 PMID:17656356 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 2:195,008,035...195,053,100
Ensembl chr 2:192,319,702...192,364,480 		JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033
GO_REF:0000104		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864 		JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000002
GO_REF:0000033		 UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 4:172,929,273...172,930,486
Ensembl chr 4:172,928,887...172,932,535 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000002
GO_REF:0000033		 UniProt
InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 NCBI chr 5:156,718,619...156,818,623
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Dbnl drebrin-like NOT|acts_upstream_of_or_within ISO (PMID:10637315) RGD PMID:10637315 NCBI chr14:80,666,115...80,681,155
Ensembl chr14:80,666,124...80,681,155 		JBrowse link
G ENSRNOG00000066279 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr20:36,411,605...36,413,032 JBrowse link
G ENSRNOG00000069335 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 4:33,576,404...33,578,930 JBrowse link
G Eps8 EGFR pathway substrate 8, signaling adaptor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:15558031), (PMID:20532239), (PMID:23314863)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15558031 PMID:20532239 PMID:23314863 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:170,388,378...170,486,873 		JBrowse link
G Flii FLII, actin remodeling protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:45,394,032...45,408,051
Ensembl chr10:45,394,032...45,407,970 		JBrowse link
G Gsn gelsolin involved_in IEA
IBA		 GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000104 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Rdx radixin IDA RGD PMID:2500445 RGD:8693627 NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Scin scinderin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:62,836,641...62,915,287
Ensembl chr 6:57,109,403...57,188,242 		JBrowse link
G Svil supervillin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:57,343,910...57,539,508
Ensembl chr17:52,648,502...52,793,404 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA
ISO		 GO_REF:0000033
(PMID:18837697)		 GO_Central
RGD		 PMID:18837697 GO_REF:0000033 NCBI chr 7:127,595,210...127,607,821
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA
ISO		 GO_REF:0000033
(PMID:18837697)		 GO_Central
RGD		 PMID:18837697 GO_REF:0000033 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298 		JBrowse link
G Vil1 villin 1 involved_in ISO
IEA		 (PMID:15272027)
GO_REF:0000107		 RGD
Ensembl		 PMID:15272027 GO_REF:0000107 NCBI chr 9:83,440,248...83,467,963
Ensembl chr 9:75,991,141...76,018,858 		JBrowse link
G Vill villin-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:118,776,718...118,794,983
Ensembl chr 8:118,776,742...118,794,983 		JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO
IEA		 (PMID:16054028)
GO_REF:0000107		 RGD
Ensembl		 PMID:16054028 GO_REF:0000107 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO
IEA		 (PMID:26466680)
GO_REF:0000107		 RGD
Ensembl		 PMID:26466680 GO_REF:0000107 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:33,574,257...33,586,965 		JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA		 (PMID:30361697)
GO_REF:0000033		 RGD
GO_Central		 PMID:30361697 GO_REF:0000033 NCBI chr14:31,638,328...31,874,391
Ensembl chr14:31,284,184...31,522,431 		JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851 		JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmod1 leiomodin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:46,754,048...46,796,186
Ensembl chr13:46,754,033...46,794,900 		JBrowse link
G Lmod2 leiomodin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Lmod3 leiomodin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:129,843,964...129,858,684
Ensembl chr 4:129,843,970...129,858,244 		JBrowse link
G Tmod1 tropomodulin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:65,112,062...65,189,563
Ensembl chr 5:60,338,512...60,393,956 		JBrowse link
G Tmod2 tropomodulin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:85,197,222...85,250,627
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
G Tmod3 tropomodulin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:76,248,978...76,310,855
Ensembl chr 8:76,248,979...76,310,977 		JBrowse link
G Tmod4 tropomodulin 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:185,384,547...185,389,549
Ensembl chr 2:182,695,709...182,700,540 		JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:23704350 RGD:11570555 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO
IBA
ISS		 (PMID:16895918)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:16895918 GO_REF:0000024 GO_REF:0000033 NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      negative regulation of cellular process 5609
        negative regulation of cellular component organization 809
          negative regulation of supramolecular fiber organization 189
            negative regulation of actin filament depolymerization 52
              actin filament capping + 46
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cellular component organization or biogenesis 7104
        cellular component organization 6817
          organelle organization 3713
            cytoskeleton organization 1595
              actin cytoskeleton organization 766
                actin filament organization 501
                  actin polymerization or depolymerization 208
                    regulation of actin polymerization or depolymerization 172
                      regulation of actin filament depolymerization 61
                        negative regulation of actin filament depolymerization 52
                          actin filament capping + 46
paths to the root