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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of actin filament depolymerization
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Accession:GO:0030834 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.
Synonyms:exact_synonym: regulation of actin depolymerization


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regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sh3bp1 SH3-domain binding protein 1 involved_in ISO (PMID:24841563) RGD PMID:24841563 NCBI chr 7:120,125,747...120,138,148
Ensembl chr 7:120,125,633...120,138,196
JBrowse link
G Wdr1 WD repeat domain 1 involved_in ISO (PMID:15629458) RGD PMID:15629458 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO (PMID:19666531)
(MGI:5619440|PMID:23325791)
RGD PMID:19666531 PMID:23325791 MGI:5619440 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Myh9 myosin, heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) RGD PMID:23325791 MGI:5619440 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G Scin scinderin involved_in ISO (PMID:19666531) RGD PMID:19666531 NCBI chr 6:59,975,375...60,055,075
Ensembl chr 6:59,976,003...60,054,279
JBrowse link
G Spta1 spectrin, alpha, erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:92,264,231...92,340,091
Ensembl chr13:92,264,231...92,340,083
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Sptb spectrin, beta, erythrocytic involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:99,657,144...99,783,189
Ensembl chr 6:99,659,651...99,783,047
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr14:114,517,839...114,700,199
Ensembl chr14:114,518,816...114,692,764
JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in IEA GO_REF:0000043
GO_REF:0000104
UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:219,964,429...220,006,811
Ensembl chr 1:219,964,429...220,005,068
JBrowse link
G Sptbn4 spectrin, beta, non-erythrocytic 4 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:84,168,494...84,254,679
Ensembl chr 1:84,168,495...84,254,645
JBrowse link
G Tpm1 tropomyosin 1 IDA RGD PMID:15779917 RGD:1600523 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Tpm1_v7 tropomyosin 1, variant 7 IDA RGD PMID:15779917 RGD:1600523
G Vil1 villin 1 involved_in ISO (PMID:16921170), (PMID:17182858), (PMID:19808673) RGD PMID:16921170 PMID:17182858 PMID:19808673 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621
JBrowse link
actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) RGD PMID:25433700 NCBI chr17:66,304,530...66,397,647
Ensembl chr17:66,304,501...66,397,653
JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 4933400A11Rik RIKEN cDNA 4933400A11 gene involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr  X:25,737,292...25,738,155 JBrowse link
G Add1 adducin 1 involved_in ISO
IBA
(PMID:8626479)
PMID:21873635
RGD PMID:8626479, PMID:21873635 RGD:13792537 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Add2 adducin 2 involved_in ISO
IBA
IEA
(PMID:8626479)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:8626479, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464
JBrowse link
G Add3 adducin 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Avil advillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
G Capg capping actin protein, gelsolin like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3758397|PMID:17656356)
RGD PMID:17656356, PMID:21873635 MGI:3758397, RGD:13792537 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:44,936,290...44,972,270
Ensembl chr 4:44,936,290...44,972,267
JBrowse link
G Capza3 capping actin protein of muscle Z-line subunit alpha 3 involved_in IBA
IEA
PMID:21873635
GO_REF:0000104
UniProt PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 4:174,181,644...174,182,857
Ensembl chr 4:174,181,644...174,182,856
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000104
(MGI:3758397|PMID:17656356)
PMID:21873635
UniProt
RGD
PMID:17656356, PMID:21873635 GO_REF:0000104 MGI:3758397, RGD:13792537 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Dbnl drebrin-like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) RGD PMID:10637315 MGI:1353214 NCBI chr14:86,029,335...86,044,364
Ensembl chr14:86,029,335...86,044,364
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:4460022|PMID:20532239), (MGI:5476881|PMID:23314863), (MGI:5486559|PMID:15558031)
UniProt
RGD
PMID:15558031 PMID:20532239 PMID:23314863 GO_REF:0000024 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Flii FLII, actin remodeling protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:46,955,460...46,969,468
Ensembl chr10:46,955,487...46,969,406
JBrowse link
G Gsn gelsolin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Rdx radixin IDA RGD PMID:2500445 RGD:8693627 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G RGD1563947 similar to RIKEN cDNA 4933400A11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:25,737,281...25,738,144 JBrowse link
G Scin scinderin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:59,975,375...60,055,075
Ensembl chr 6:59,976,003...60,054,279
JBrowse link
G Svil supervillin involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:55,230,298...55,425,967
Ensembl chr17:55,230,298...55,346,279
JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in IBA
ISO
PMID:21873635
(MGI:3840765|PMID:18837697)
RGD PMID:18837697, PMID:21873635 MGI:3840765, RGD:13792537 NCBI chr 7:135,838,647...135,850,542
Ensembl chr 7:135,838,648...135,850,542
JBrowse link
G Twf2 twinfilin actin-binding protein 2 involved_in IBA
ISO
PMID:21873635
(MGI:3840765|PMID:18837697)
RGD PMID:18837697, PMID:21873635 MGI:3840765, RGD:13792537 NCBI chr 8:114,897,011...114,909,531
Ensembl chr 8:114,897,011...114,909,531
JBrowse link
G Vil1 villin 1 involved_in ISO
IBA
(PMID:15272027)
PMID:21873635
RGD PMID:15272027, PMID:21873635 RGD:13792537 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621
JBrowse link
G Vill villin-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:127,735,233...127,753,313
Ensembl chr 8:127,735,258...127,753,349
JBrowse link
barbed-end actin filament uncapping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
negative regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in ISO
ISS
(PMID:12566430)
GO_REF:0000024
RGD
UniProt
PMID:12566430 GO_REF:0000024 NCBI chr 7:141,428,113...141,528,447
Ensembl chr 7:141,428,063...141,528,397
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO (MGI:6450443|PMID:30568254) RGD PMID:30568254 MGI:6450443 NCBI chr 2:118,831,350...118,861,456
Ensembl chr 2:118,831,350...118,861,454
JBrowse link
G Plekhh2 pleckstrin homology, MyTH4 and FERM domain containing H2 involved_in ISO (MGI:5487756|PMID:22832517) RGD PMID:22832517 MGI:5487756 NCBI chr 6:7,784,743...7,895,986
Ensembl chr 6:7,793,735...7,893,769
JBrowse link
G Shroom2 shroom family member 2 acts_upstream_of_or_within ISO (MGI:3723326|PMID:17666436) RGD PMID:17666436 MGI:3723326 NCBI chr  X:23,478,869...23,649,424
Ensembl chr  X:23,478,871...23,649,466
JBrowse link
G Specc1l sperm antigen with calponin homology and coiled-coil domains 1-like acts_upstream_of_or_within ISO (MGI:5433266|PMID:21703590) RGD PMID:21703590 MGI:5433266 NCBI chr20:14,287,470...14,393,879
Ensembl chr20:14,287,457...14,393,793
JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 involved_in ISO (MGI:5554982|PMID:23921380) RGD PMID:23921380 MGI:5554982 NCBI chr 1:174,862,683...174,924,101
Ensembl chr 1:174,862,698...174,924,078
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) RGD PMID:16054028 MGI:3588909 NCBI chr17:43,050,282...43,339,403
Ensembl chr17:43,050,789...43,339,403
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) RGD PMID:26466680 NCBI chr19:37,652,383...37,665,333
Ensembl chr19:37,652,969...37,668,019
JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics involved_in ISO
IBA
(PMID:30361697)
PMID:21873635
RGD PMID:30361697, PMID:21873635 RGD:13792537 NCBI chr14:33,649,989...33,783,794
Ensembl chr14:33,649,637...33,677,031
JBrowse link
G Washc2c WASH complex subunit 2C involved_in ISO (PMID:20498093) RGD PMID:20498093 NCBI chr 4:148,139,512...148,197,363
Ensembl chr 4:148,139,528...148,197,365
JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmod1 leiomodin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G Lmod2 leiomodin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:51,553,439...51,561,135
Ensembl chr 4:51,553,454...51,561,174
JBrowse link
G Lmod3 leiomodin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:129,604,378...129,619,136
Ensembl chr 4:129,604,267...129,619,142
JBrowse link
G Tmod1 tropomodulin 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:61,635,244...61,712,052
Ensembl chr 5:61,657,507...61,712,051
JBrowse link
G Tmod2 tropomodulin 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:82,505,947...82,547,450
Ensembl chr 8:82,506,934...82,533,689
JBrowse link
G Tmod3 tropomodulin 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:82,432,165...82,492,243
Ensembl chr 8:82,432,169...82,492,243
JBrowse link
G Tmod4 tropomodulin 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:196,294,990...196,299,896
Ensembl chr 2:196,295,069...196,299,896
JBrowse link
positive regulation of actin filament depolymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC093995.1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 1:79,727,597...79,728,113 JBrowse link
G Cfl1 cofilin 1 involved_in
acts_upstream_of_or_within
ISO (MGI:5554982|PMID:23921380)
(MGI:3575233|PMID:15548599)
RGD PMID:15548599 PMID:23921380 MGI:3575233 MGI:5554982 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cfl2 cofilin 2 involved_in ISO (PMID:17160903) RGD PMID:17160903 NCBI chr 6:75,759,140...75,763,185
Ensembl chr 6:75,759,140...75,763,185
JBrowse link
G Dstn destrin, actin depolymerizing factor acts_upstream_of_or_within ISO (MGI:3575233|PMID:15548599) RGD PMID:15548599 MGI:3575233 NCBI chr 3:138,024,508...138,051,304
Ensembl chr 3:138,024,508...138,051,298
JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:17500066) RGD PMID:17500066 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Pdxp pyridoxal phosphatase involved_in ISO
ISS
IEA
(PMID:15580268)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:15580268 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:120,140,460...120,145,908
Ensembl chr 7:120,140,460...120,145,908
JBrowse link
G Plek pleckstrin involved_in ISO (PMID:10497244)
(MGI:3844782|PMID:19190246)
RGD PMID:10497244 PMID:19190246 MGI:3844782 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
G Sema5a semaphorin 5A involved_in ISS
ISO
GO_REF:0000024
(MGI:5526935|PMID:19850054)
UniProt
RGD
PMID:19850054 GO_REF:0000024 MGI:5526935 NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
JBrowse link
G Vil1 villin 1 involved_in ISO (PMID:15272027) RGD PMID:15272027 NCBI chr 9:81,689,802...81,717,623
Ensembl chr 9:81,689,802...81,717,621
JBrowse link
G Wdr1 WD repeat domain 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:101763 (MGI:5574550|PMID:24840128)
RGD PMID:24840128, PMID:21873635 MGI:5574550, RGD:13792537 NCBI chr14:76,990,014...77,023,739
Ensembl chr14:76,989,919...77,023,726
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc2 actin related protein 2/3 complex, subunit 2 IMP RGD PMID:15252126 RGD:2306210 NCBI chr 9:81,518,163...81,548,871
Ensembl chr 9:81,518,176...81,548,871
JBrowse link
G Cfl1 cofilin 1 IMP RGD PMID:23704350 RGD:11570555 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtpn myotrophin involved_in ISO
ISS
IBA
(PMID:16895918)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:16895918, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 4:63,012,009...63,039,422
Ensembl chr 4:63,012,011...63,039,422
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    regulation of biological process 12857
      regulation of cellular process 12354
        regulation of cellular component organization 2589
          regulation of protein-containing complex disassembly 136
            regulation of protein depolymerization 100
              regulation of actin filament depolymerization 61
                negative regulation of actin filament depolymerization + 51
                positive regulation of actin filament depolymerization + 15
                regulation of barbed-end actin filament capping + 7
Path 2
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      cellular component organization or biogenesis 6724
        cellular component organization 6479
          organelle organization 4057
            cytoskeleton organization 1447
              actin cytoskeleton organization 744
                actin filament organization 466
                  regulation of actin filament organization 288
                    regulation of actin polymerization or depolymerization 200
                      regulation of actin filament depolymerization 61
                        negative regulation of actin filament depolymerization + 51
                        positive regulation of actin filament depolymerization + 15
                        regulation of barbed-end actin filament capping + 7
paths to the root