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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of actin filament polymerization
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Accession:GO:0030833 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
Synonyms:exact_synonym: regulation of actin polymerization


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regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABITRAM actin binding transcription modulator involved_in ISO (MGI:5632379|PMID:24782708) UniProt PMID:24782708 MGI:5632379 NCBI chr 9:80,085,138...80,101,685
Ensembl chr 9:108,258,285...108,274,538
JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 involved_in ISO (PMID:21865595) UniProt PMID:21865595 NCBI chr 6:127,368,377...127,558,136
Ensembl chr 6:131,477,383...131,609,221
JBrowse link
G CLEC2A C-type lectin domain family 2 member A acts_upstream_of_or_within ISO (MGI:3622591|PMID:16143319) MGI PMID:16143319 MGI:3622591 NCBI chr12:9,959,826...9,981,376
Ensembl chr12:10,195,862...10,229,273
JBrowse link
G CORO1A coronin 1A acts_upstream_of_or_within ISO (MGI:3818245|PMID:18836449) MGI PMID:18836449 MGI:3818245 Ensembl chr16:30,550,383...30,556,196 JBrowse link
G DBN1 drebrin 1 ISO RGD PMID:19222710 RGD:10395284 NCBI chr 5:172,758,316...172,774,974
Ensembl chr 5:179,820,791...179,836,872
JBrowse link
G ELN elastin acts_upstream_of_or_within ISO (MGI:3027647|PMID:14614988) MGI PMID:14614988 MGI:3027647
G ESAM endothelial cell adhesion molecule involved_in ISO (PMID:20298433) ARUK-UCL PMID:20298433 NCBI chr11:119,580,140...119,589,338
Ensembl chr11:123,495,779...123,504,938
JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in ISO (MGI:5661753|PMID:25803043) UniProt PMID:25803043 MGI:5661753 NCBI chr 9:35,587,876...35,599,971
Ensembl chr 9:36,390,409...36,402,949
JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chr 1:129,627,564...129,630,920
Ensembl chr 1:133,241,077...133,244,431
JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chr 3:118,733,505...118,763,177
Ensembl chr 3:125,642,973...125,669,095
JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in ISO (PMID:15220930) UniProt PMID:15220930 NCBI chr 6:147,476,913...147,533,491
Ensembl chr 6:152,182,394...152,239,276
JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in ISO (PMID:21177870) UniProt PMID:21177870 NCBI chr  X:100,060,647...100,345,491
Ensembl chr  X:110,672,664...110,797,992
JBrowse link
G PFN2 profilin 2 ISO RGD PMID:11027290 RGD:727303 NCBI chr 3:146,986,364...146,992,558 JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 acts_upstream_of_or_within ISO (MGI:5613738|PMID:25217619) MGI PMID:25217619 MGI:5613738 NCBI chr19:17,632,265...17,649,664 JBrowse link
G PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 involved_in ISO (PMID:26573021) UniProt PMID:26573021 NCBI chr19:36,510,855...36,526,623
Ensembl chr19:45,058,562...45,071,940
JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:15473970 RGD:10043779 NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220
JBrowse link
G PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 ISO RGD PMID:18697831 RGD:2314615 NCBI chr20:44,965,850...45,169,891
Ensembl chr20:46,033,937...46,226,500
JBrowse link
G RASA1 RAS p21 protein activator 1 involved_in ISO (PMID:8344248) UniProt PMID:8344248 NCBI chr 5:27,980,907...28,104,368
Ensembl chr 5:28,115,159...28,240,321
JBrowse link
'de novo' actin filament nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JMY junction mediating and regulatory protein, p53 cofactor involved_in ISO (MGI:4418600|PMID:19287377) UniProt PMID:19287377 MGI:4418600 NCBI chr 5:35,981,666...36,076,428
Ensembl chr 5:36,261,971...36,567,349
JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in ISO (PMID:19666531)
(MGI:5619440|PMID:23325791)
UniProt PMID:19666531 PMID:23325791 MGI:5619440 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G MYH9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618
JBrowse link
G SCIN scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 7:13,269,361...13,351,854
Ensembl chr 7:12,613,996...12,696,244
JBrowse link
G TPM1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chr15:41,989,239...42,018,520
Ensembl chr15:60,286,587...60,315,530
JBrowse link
G VIL1 villin 1 involved_in ISO (PMID:16921170), (PMID:17182858), (PMID:19808673) UniProt PMID:16921170 PMID:17182858 PMID:19808673 NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550
JBrowse link
actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMOD1 leiomodin 1 involved_in ISO (PMID:26370058) UniProt PMID:26370058 NCBI chr 1:177,493,627...177,543,853
Ensembl chr 1:181,798,304...181,845,295
JBrowse link
G LMOD2 leiomodin 2 involved_in ISO (PMID:25250574)
(PMID:20685966), (PMID:26370058)
UniProt PMID:20685966 PMID:25250574 PMID:26370058 NCBI chr 7:115,649,102...115,657,174
Ensembl chr 7:128,331,803...128,340,263
JBrowse link
G LMOD3 leiomodin 3 involved_in ISO (PMID:25250574) UniProt PMID:25250574 NCBI chr 3:69,042,870...69,058,704
Ensembl chr 3:70,410,288...70,424,702
JBrowse link
Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 involved_in ISO (PMID:11741539), (PMID:17220302), (PMID:29925947) FlyBase PMID:11741539 PMID:17220302 PMID:29925947 NCBI chr2A:65,289,675...65,333,219 JBrowse link
G ACTR3 actin related protein 3 involved_in ISO (PMID:11741539), (PMID:17220302) FlyBase PMID:11741539 PMID:17220302 NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729
JBrowse link
G ARPC1B actin related protein 2/3 complex subunit 1B involved_in ISO (PMID:11741539) FlyBase PMID:11741539 NCBI chr 7:91,348,120...91,368,299
Ensembl chr 7:104,861,582...104,870,369
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in ISO (PMID:11741539) FlyBase PMID:11741539 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 involved_in ISO (PMID:11741539) FlyBase PMID:11741539 NCBI chr12:108,007,884...108,023,386
Ensembl chr12:111,399,433...111,415,156
JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 involved_in ISO (PMID:11741539) FlyBase PMID:11741539 NCBI chr 3:9,744,055...9,758,627
Ensembl chr 3:9,981,934...9,996,250
JBrowse link
G ARPC5 actin related protein 2/3 complex subunit 5 involved_in ISO (PMID:11741539) FlyBase PMID:11741539 NCBI chr 1:159,156,229...159,165,898
Ensembl chr 1:163,311,111...163,323,554
JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 involved_in ISO (PMID:12515716) UniProt PMID:12515716 NCBI chr 5:38,593,574...38,900,327
Ensembl chr 5:39,138,359...39,516,596
JBrowse link
G JMY junction mediating and regulatory protein, p53 cofactor involved_in ISO (MGI:4418600|PMID:19287377) UniProt PMID:19287377 MGI:4418600 NCBI chr 5:35,981,666...36,076,428
Ensembl chr 5:36,261,971...36,567,349
JBrowse link
G MAGEL2 MAGE family member L2 involved_in ISO (PMID:23452853) UniProt PMID:23452853 NCBI chr15:6,017,523...6,021,849
Ensembl chr15:21,134,857...21,138,576
JBrowse link
G TRIM27 tripartite motif containing 27 involved_in ISO (PMID:23452853) UniProt PMID:23452853 NCBI chr 6:28,722,505...28,743,484
Ensembl chr 6:29,390,423...29,411,308
JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chr 4:2,986,301...3,072,590
Ensembl chr 4:2,920,781...2,975,012
JBrowse link
G ADD2 adducin 2 involved_in ISO (PMID:8626479) BHF-UCL PMID:8626479 NCBI chr2A:70,724,454...70,831,248
Ensembl chr2A:71,839,470...71,895,106
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 acts_upstream_of_or_within ISO (MGI:3758397|PMID:17656356) MGI PMID:17656356 MGI:3758397 NCBI chr 1:115,273,497...115,324,353
Ensembl chr 1:125,028,519...125,078,892
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta acts_upstream_of_or_within ISO (MGI:3758397|PMID:17656356) MGI PMID:17656356 MGI:3758397 NCBI chr 1:18,297,434...18,444,011
Ensembl chr 1:19,344,154...19,488,133
JBrowse link
G DBNL drebrin like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) MGI PMID:10637315 MGI:1353214 NCBI chr 7:44,753,062...44,775,717
Ensembl chr 7:44,824,608...44,845,891
JBrowse link
G EPS8 epidermal growth factor receptor pathway substrate 8 involved_in ISO (MGI:5476881|PMID:23314863)
(MGI:4460022|PMID:20532239), (MGI:5486559|PMID:15558031)
UniProt PMID:15558031 PMID:20532239 PMID:23314863 MGI:4460022 MGI:5476881 MGI:5486559 NCBI chr12:15,617,536...15,788,537
Ensembl chr12:16,013,276...16,076,117
JBrowse link
G RDX radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chr11:105,075,716...105,176,660
Ensembl chr11:108,921,477...109,005,557
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404
JBrowse link
G VIL1 villin 1 involved_in ISO (PMID:15272027) UniProt PMID:15272027 NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550
JBrowse link
negative regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 ISO RGD PMID:8675693 RGD:7174724 NCBI chr 4:2,986,301...3,072,590
Ensembl chr 4:2,920,781...2,975,012
JBrowse link
G ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 involved_in ISO (PMID:22084092) UniProt PMID:22084092 NCBI chr 8:63,740,512...63,884,189
Ensembl chr 8:65,403,386...65,545,789
JBrowse link
G BBS4 Bardet-Biedl syndrome 4 acts_upstream_of_or_within ISO (MGI:5510934|PMID:23716571) MGI PMID:23716571 MGI:5510934 NCBI chr15:51,601,526...51,656,460
Ensembl chr15:70,362,261...70,416,964
JBrowse link
G CAPN1 calpain 1 ISO RGD PMID:25653381 RGD:13792590 NCBI chr11:60,545,837...60,576,631
Ensembl chr11:63,886,015...63,916,021
JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in ISO (PMID:30250061) UniProt PMID:30250061 NCBI chr 8:126,478,020...126,653,936
Ensembl chr 8:129,209,655...129,272,844
JBrowse link
G FHOD3 formin homology 2 domain containing 3 acts_upstream_of_or_within ISO (MGI:4422153|PMID:19706596) MGI PMID:19706596 MGI:4422153 NCBI chr18:29,550,049...30,033,130
Ensembl chr18:33,165,819...33,590,154
JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in ISO (PMID:17318189)
(MGI:5805366|PMID:17318189)
ParkinsonsUK-UCL PMID:17318189 MGI:5805366 NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726
JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in
acts_upstream_of_or_within
ISO (PMID:18458160)
(PMID:17996375)
UniProt
MGI
PMID:17996375 PMID:18458160 NCBI chr 9:550,713...556,230 JBrowse link
G MKKS MKKS centrosomal shuttling protein acts_upstream_of_or_within ISO (MGI:5510934|PMID:23716571) MGI PMID:23716571 MGI:5510934 NCBI chr20:10,346,252...10,380,180
Ensembl chr20:10,351,309...10,366,863
JBrowse link
G MYADM myeloid associated differentiation marker involved_in ISO (PMID:23264465) UniProt PMID:23264465 NCBI chr19:50,807,615...50,817,196
Ensembl chr19:59,663,790...59,664,758
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr17:58,417,134...58,526,409
Ensembl chr17:63,511,784...63,579,067
JBrowse link
G PFN1 profilin 1 involved_in ISO (PMID:7758455) UniProt PMID:7758455 NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022
JBrowse link
G PFN2 profilin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:7758455)
(MGI:4844066|PMID:18001770)
UniProt
MGI
PMID:7758455 PMID:18001770 MGI:4844066 NCBI chr 3:146,986,364...146,992,558 JBrowse link
G PRKCD protein kinase C delta involved_in ISO (MGI:3813784|PMID:16940418) UniProt PMID:16940418 MGI:3813784 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in ISO (PMID:19759280) UniProt PMID:19759280 NCBI chr 4:14,654,448...15,023,708
Ensembl chr 4:20,158,952...20,314,656
JBrowse link
G TLR2 toll like receptor 2 involved_in ISO (MGI:5307186|PMID:22198949) ARUK-UCL PMID:22198949 MGI:5307186 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in ISO (MGI:2673741|PMID:12807912) BHF-UCL PMID:12807912 MGI:2673741 NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404
JBrowse link
negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPIN actin related protein 2/3 complex inhibitor involved_in ISO (PMID:24132237) UniProt PMID:24132237 NCBI chr15:68,585,634...68,602,105 JBrowse link
G CORO1A coronin 1A involved_in ISO (PMID:17442961) UniProt PMID:17442961 Ensembl chr16:30,550,383...30,556,196 JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1B coronin 1B involved_in ISO (PMID:17350576), (PMID:18775315) UniProt PMID:17350576 PMID:18775315 NCBI chr11:62,796,461...62,802,204
Ensembl chr11:66,108,924...66,113,175
JBrowse link
G CTNNA2 catenin alpha 2 involved_in ISO (PMID:30013181) UniProt PMID:30013181 NCBI chr2A:79,594,694...80,745,885
Ensembl chr2A:81,303,559...82,307,258
JBrowse link
G DNAI3 dynein axonemal intermediate chain 3 involved_in ISO (PMID:32128961) UniProt PMID:32128961 NCBI chr 1:117,617,609...117,690,284
Ensembl chr 1:86,474,457...86,547,080
JBrowse link
G GMFG glia maturation factor gamma acts_upstream_of_or_within ISO (MGI:5505367|PMID:23727094) MGI PMID:23727094 MGI:5505367 NCBI chr19:36,426,652...36,440,031
Ensembl chr19:44,974,435...44,982,209
JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in ISO (MGI:5805366|PMID:17318189) ParkinsonsUK-UCL PMID:17318189 MGI:5805366 NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726
JBrowse link
G LOC100972387 DNA-directed RNA polymerases I, II, and III subunit RPABC2 involved_in ISO PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chr22:18,868,872...18,988,918
Ensembl chr22:36,796,015...36,814,469
Ensembl chr22:36,796,015...36,814,469
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) UniProt PMID:16054028 MGI:3588909 NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680) UniProt PMID:26466680 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709
JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chr 4:67,598,880...67,880,269
Ensembl chr 4:74,167,488...74,199,802
JBrowse link
positive regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:18256280 RGD:2306202 NCBI chr2B:827,184...900,424
Ensembl chr2B:114,373,392...114,445,729
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in ISO (MGI:5508294|PMID:11278875) UniProt PMID:11278875 MGI:5508294 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669
JBrowse link
G ARF6 ADP ribosylation factor 6 involved_in ISO (PMID:10036235) UniProt PMID:10036235 NCBI chr14:30,482,191...30,486,741
Ensembl chr14:48,789,329...48,789,856
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 acts_upstream_of_or_within ISO (MGI:3818245|PMID:18836449) MGI PMID:18836449 MGI:3818245 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643
JBrowse link
G BAG4 BAG cochaperone 4 involved_in ISO (MGI:5292318|PMID:21712384) UniProt PMID:21712384 MGI:5292318 NCBI chr 8:37,479,231...37,515,303
Ensembl chr 8:34,656,000...34,692,666
JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 involved_in ISO (PMID:21098279) UniProt PMID:21098279 NCBI chr 7:6,158,306...6,230,903
Ensembl chr 7:103,758,479...103,828,874
JBrowse link
G BIN1 bridging integrator 1 involved_in ISO (MGI:5583915|PMID:24836577) ARUK-UCL PMID:24836577 MGI:5583915 NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378
JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) UniProt PMID:16054028 MGI:3588909 NCBI chr 6:25,114,221...25,454,984
Ensembl chr 6:25,441,682...25,780,092
JBrowse link
G CCL11 C-C motif chemokine ligand 11 involved_in ISO (PMID:19525930) BHF-UCL PMID:19525930 NCBI chr17:22,495,737...22,515,144
Ensembl chr17:22,806,076...22,808,345
Ensembl chr17:22,806,076...22,808,345
JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in ISO (PMID:11242036) BHF-UCL PMID:11242036 NCBI chr 9:34,545,248...34,546,801
Ensembl chr 9:35,353,768...35,354,924
JBrowse link
G CCL24 C-C motif chemokine ligand 24 involved_in ISO (PMID:19525930) BHF-UCL PMID:19525930 NCBI chr 7:68,206,688...68,210,343
Ensembl chr 7:82,263,310...82,265,480
JBrowse link
G CCL26 C-C motif chemokine ligand 26 involved_in ISO (PMID:19525930) BHF-UCL PMID:19525930 NCBI chr 7:68,230,804...68,251,369
Ensembl chr 7:82,221,846...82,242,874
JBrowse link
G CDC42EP2 CDC42 effector protein 2 involved_in ISO (PMID:11035016) UniProt PMID:11035016 NCBI chr11:60,679,582...60,686,763
Ensembl chr11:64,024,281...64,024,913
JBrowse link
G CDC42EP5 CDC42 effector protein 5 involved_in ISO (PMID:11035016) UniProt PMID:11035016 NCBI chr19:51,411,848...51,419,686 JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chr 4:67,598,880...67,880,269
Ensembl chr 4:74,167,488...74,199,802
JBrowse link
G CSF3 colony stimulating factor 3 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chr17:17,271,074...17,273,493
Ensembl chr17:17,491,276...17,493,729
JBrowse link
G CTTN cortactin involved_in ISO (PMID:24700464)
PMID:18768925
UniProt PMID:18768925 PMID:24700464 RGD:10047281 NCBI chr11:65,500,074...65,539,158
Ensembl chr11:68,794,162...68,823,857
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within ISO (MGI:3528803|PMID:15699074) MGI PMID:15699074 MGI:3528803 NCBI chr 3:194,386,263...194,648,015
Ensembl chr 3:204,323,724...204,584,987
JBrowse link
G EVL Enah/Vasp-like involved_in ISO (MGI:5545940|PMID:23153535) UniProt PMID:23153535 MGI:5545940 NCBI chr14:80,594,889...80,767,652
Ensembl chr14:100,005,645...100,084,598
JBrowse link
G FCHSD1 FCH and double SH3 domains 1 involved_in ISO (MGI:6233193|PMID:23437151) UniProt PMID:23437151 MGI:6233193 NCBI chr 5:137,000,158...137,012,379 JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in ISO (MGI:6233193|PMID:23437151) UniProt PMID:23437151 MGI:6233193 NCBI chr11:67,915,796...68,219,482 JBrowse link
G FER FER tyrosine kinase involved_in ISO (PMID:19738202) UniProt PMID:19738202 NCBI chr 5:104,099,620...104,548,077
Ensembl chr 5:109,964,823...110,350,576
JBrowse link
G FMN1 formin 1 acts_upstream_of_or_within ISO (MGI:3027450|PMID:14647292) MGI PMID:14647292 MGI:3027450 NCBI chr15:11,271,794...11,698,539
Ensembl chr15:30,114,113...30,495,909
JBrowse link
G GRB2 growth factor receptor bound protein 2 acts_upstream_of_or_within ISO (MGI:3768467|PMID:17923684) MGI PMID:17923684 MGI:3768467 NCBI chr17:69,265,307...69,352,835
Ensembl chr17:74,817,471...74,903,796
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr19:9,821,402...9,837,021
Ensembl chr19:10,484,414...10,500,605
JBrowse link
G KIRREL1 kirre like nephrin family adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:3768467|PMID:17923684) MGI PMID:17923684 MGI:3768467 NCBI chr 1:133,363,880...133,465,717
Ensembl chr 1:137,233,701...137,255,927
JBrowse link
G LMOD1 leiomodin 1 involved_in ISO (PMID:26370058) UniProt PMID:26370058 NCBI chr 1:177,493,627...177,543,853
Ensembl chr 1:181,798,304...181,845,295
JBrowse link
G LMOD2 leiomodin 2 involved_in ISO (PMID:26370058) UniProt PMID:26370058 NCBI chr 7:115,649,102...115,657,174
Ensembl chr 7:128,331,803...128,340,263
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (MGI:2674169|PMID:12941696), (MGI:5608927|PMID:25224220) MGI PMID:12941696 PMID:25224220 MGI:2674169 MGI:5608927 NCBI chr 5:57,116,405...57,197,017
Ensembl chr 5:58,745,579...58,826,959
JBrowse link
G MLST8 MTOR associated protein, LST8 homolog acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) MGI PMID:15467718 MGI:3510095 NCBI chr16:1,063,534...1,067,706
Ensembl chr16:2,306,451...2,310,828
JBrowse link
G MTOR mechanistic target of rapamycin kinase acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) MGI PMID:15467718 MGI:3510095 NCBI chr 1:9,871,700...10,028,704
Ensembl chr 1:11,093,765...11,249,841
JBrowse link
G MYO1C myosin IC ISO RGD PMID:22918957 RGD:11073622 NCBI chr17:1,446,506...1,475,634
Ensembl chr17:1,345,143...1,375,540
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12110186)
(MGI:3768467|PMID:17923684)
UniProt
MGI
PMID:12110186 PMID:17923684 MGI:3768467 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in ISO (PMID:12110186) UniProt PMID:12110186 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G NCKAP1 NCK associated protein 1 involved_in ISO (MGI:5897521|PMID:27927633) BHF-UCL PMID:27927633 MGI:5897521 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in ISO (MGI:3818191|PMID:19015308)
(PMID:16417406), (PMID:32647003)
UniProt PMID:16417406 PMID:19015308 PMID:32647003 MGI:3818191 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881
JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin acts_upstream_of_or_within ISO (MGI:3768467|PMID:17923684) MGI PMID:17923684 MGI:3768467 NCBI chr19:32,742,802...32,770,600
Ensembl chr19:41,492,444...41,518,471
JBrowse link
G PFN1 profilin 1 involved_in ISO (PMID:23153535) UniProt PMID:23153535 NCBI chr17:4,993,853...4,996,811
Ensembl chr17:4,981,765...4,985,022
JBrowse link
G PFN2 profilin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:23153535)
(MGI:3714870|PMID:17541406)
UniProt
MGI
PMID:17541406 PMID:23153535 MGI:3714870 NCBI chr 3:146,986,364...146,992,558 JBrowse link
G PRKCE protein kinase C epsilon involved_in ISO (MGI:5306325|PMID:11746497) UniProt PMID:11746497 MGI:5306325 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in ISO (PMID:18765415) UniProt PMID:18765415 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO (MGI:5291858|PMID:21892172) UniProt PMID:21892172 MGI:5291858 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828
JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (MGI:2668778|PMID:12853475) MGI PMID:12853475 MGI:2668778 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17369454 RGD:1642965 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 acts_upstream_of_or_within ISO (MGI:3510095|PMID:15467718) MGI PMID:15467718 MGI:3510095 NCBI chr 5:71,299,215...71,435,290
Ensembl chr 5:76,389,130...76,469,830
JBrowse link
G SNX9 sorting nexin 9 involved_in ISO (MGI:6233193|PMID:23437151) UniProt PMID:23437151 MGI:6233193 NCBI chr 6:155,724,026...155,844,553
Ensembl chr 6:157,824,918...157,903,357
JBrowse link
G TENM1 teneurin transmembrane protein 1 involved_in ISO (MGI:5465054|PMID:22698694) UniProt PMID:22698694 MGI:5465054 NCBI chr  X:113,568,341...114,399,131
Ensembl chr  X:123,742,330...124,333,000
JBrowse link
G VASP vasodilator stimulated phosphoprotein involved_in ISO (PMID:23153535) UniProt PMID:23153535 NCBI chr19:42,457,222...42,476,688
Ensembl chr19:51,053,567...51,072,553
JBrowse link
positive regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FMN1 formin 1 acts_upstream_of_or_within ISO (MGI:3027450|PMID:14647292) MGI PMID:14647292 MGI:3027450 NCBI chr15:11,271,794...11,698,539
Ensembl chr15:30,114,113...30,495,909
JBrowse link
G GSN gelsolin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G MAGEL2 MAGE family member L2 acts_upstream_of_or_within ISO (MGI:5603599|PMID:23452853) MGI PMID:23452853 MGI:5603599 NCBI chr15:6,017,523...6,021,849
Ensembl chr15:21,134,857...21,138,576
JBrowse link
G SCIN scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 7:13,269,361...13,351,854
Ensembl chr 7:12,613,996...12,696,244
JBrowse link
G TRIM27 tripartite motif containing 27 acts_upstream_of_or_within ISO (MGI:5603599|PMID:23452853) MGI PMID:23452853 MGI:5603599 NCBI chr 6:28,722,505...28,743,484
Ensembl chr 6:29,390,423...29,411,308
JBrowse link
G WHAMM WASP homolog associated with actin, golgi membranes and microtubules involved_in ISO (PMID:18614018) UniProt PMID:18614018 NCBI chr15:62,763,534...62,788,639
Ensembl chr15:80,706,760...80,730,006
JBrowse link
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr2B:90,561,708...90,663,072
Ensembl chr2B:208,702,092...208,797,499
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr 3:10,051,054...10,062,364
Ensembl chr 3:10,403,896...10,415,545
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 Ensembl chr15:20,462,811...20,573,684 JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in ISO (PMID:29887380) UniProt PMID:29887380 NCBI chr11:67,915,796...68,219,482 JBrowse link
G NCKAP1 NCK associated protein 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr2B:70,193,950...70,308,442
Ensembl chr2B:188,003,235...188,116,710
JBrowse link
G WASF1 WASP family member 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr 6:107,911,751...107,988,821
Ensembl chr 6:111,951,726...111,979,329
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr2B:105,478,035...105,513,665
Ensembl chr2B:224,076,356...224,111,643
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chr11:61,215,092...61,218,628
Ensembl chr11:64,544,275...64,550,806
JBrowse link
regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VIL1 villin 1 involved_in ISO (PMID:16921170), (PMID:17182858), (PMID:19808673) UniProt PMID:16921170 PMID:17182858 PMID:19808673 NCBI chr2B:105,677,371...105,711,293
Ensembl chr2B:224,274,548...224,304,550
JBrowse link
G WASHC5 WASH complex subunit 5 acts_upstream_of_or_within ISO (MGI:5883184|PMID:27390154) MGI PMID:27390154 MGI:5883184 NCBI chr 8:121,710,118...121,777,977
Ensembl chr 8:124,461,424...124,529,262
JBrowse link
regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1AR adaptor related protein complex 1 associated regulatory protein acts_upstream_of_or_within ISO (MGI:5429457|PMID:22689987) MGI PMID:22689987 MGI:5429457 NCBI chr 4:104,720,583...104,762,097
Ensembl chr 4:115,282,727...115,322,872
JBrowse link
G ARF1 ADP ribosylation factor 1 involved_in ISO PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chr 1:203,484,803...203,501,395
Ensembl chr 1:208,695,615...208,712,105
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTPN myotrophin involved_in ISO (PMID:16895918) UniProt PMID:16895918 NCBI chr 7:127,896,148...127,947,122
Ensembl chr 7:140,392,620...140,443,591
JBrowse link
sequestering of actin monomers term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831
JBrowse link
G SCIN scinderin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 7:13,269,361...13,351,854
Ensembl chr 7:12,613,996...12,696,244
JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in ISO (PMID:1447300), (PMID:1999398) CAFA PMID:1447300 PMID:1999398 NCBI chr  X:5,587,242...5,589,417 JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in ISO (MGI:3840765|PMID:18837697) BHF-UCL PMID:18837697 MGI:3840765 NCBI chr12:44,925,701...44,938,344
Ensembl chr12:45,794,763...45,807,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12614
    regulation of biological process 8690
      regulation of cellular process 8215
        regulation of cellular component organization 2345
          regulation of protein-containing complex assembly 389
            regulation of protein polymerization 178
              regulation of actin filament polymerization 119
                negative regulation of actin filament polymerization + 35
                positive regulation of actin filament polymerization + 78
                regulation of actin nucleation + 24
                regulation of barbed-end actin filament capping + 6
Path 2
Term Annotations click to browse term
  biological_process 12614
    cellular process 11742
      cellular component organization or biogenesis 5098
        cellular component organization 5015
          organelle organization 3108
            cytoskeleton organization 1110
              actin cytoskeleton organization 552
                actin filament organization 336
                  actin polymerization or depolymerization 163
                    regulation of actin polymerization or depolymerization 137
                      regulation of actin filament polymerization 119
                        negative regulation of actin filament polymerization + 35
                        positive regulation of actin filament polymerization + 78
                        regulation of actin nucleation + 24
                        regulation of barbed-end actin filament capping + 6
paths to the root