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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
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Accession:GO:0030697 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + uridine54 in tRNA = 5-methyluridine54 in tRNA + H+ + S-adenosyl-L-homocysteine.
Synonyms:exact_synonym: S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity;   S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity;   tRNA (uracil(54)-C(5))-methyltransferase activity, S-adenosyl methionine-dependent
 broad_synonym: RUMT;   ribothymidyl synthase activity
 related_synonym: M5U-methyltransferase activity;   RUMT activity;   S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity;   tRNA uracil 5-methyltransferase activity;   tRNA:m(5)U54-methyltransferase activity;   tRNA:m5U54-methyltransferase activity;   transfer RNA uracil 5-methyltransferase activity;   transfer RNA uracil methylase activity
 alt_id: GO:0009021
 xref: EC:2.1.1.35;   MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN;   RHEA:42712


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tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt2a tRNA methyltransferase 2 homolog A enables ISO (PMID:31361898), (PMID:33799331) RGD PMID:31361898 PMID:33799331 NCBI chr11:82,737,689...82,742,423
Ensembl chr11:82,737,689...82,742,336 		JBrowse link
G Trmt2b tRNA methyltransferase 2 homolog B enables ISO (PMID:31948311)
(PMID:31736397)		 RGD PMID:31736397 PMID:31948311 NCBI chr  X:97,425,712...97,483,821 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21087
    catalytic activity 6127
      transferase activity 2447
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent 2
Path 2
Term Annotations click to browse term
  molecular_function 21087
    catalytic activity 6127
      transferase activity 2447
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            RNA methyltransferase activity 63
              tRNA methyltransferase activity 31
                tRNA (uridine) methyltransferase activity 5
                  tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent 2
paths to the root