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ONTOLOGY REPORT - ANNOTATIONS


Term:ubiquitin-dependent SMAD protein catabolic process
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Accession:GO:0030579 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.
Synonyms:exact_synonym: ubiquitin-dependent SMAD protein breakdown;   ubiquitin-dependent SMAD protein catabolism;   ubiquitin-dependent SMAD protein degradation



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ubiquitin-dependent SMAD protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf111 ring finger protein 111 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3628833|PMID:16601693)
RGD PMID:16601693 PMID:21873635 MGI:3628833, RGD:13792537 NCBI chr 8:71,103,967...71,180,172
Ensembl chr 8:71,103,973...71,145,070
JBrowse link
G Smurf1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IBA
ISO
PMID:21873635
(PMID:11278251), (PMID:12151385)
RGD PMID:11278251 PMID:12151385 PMID:21873635 RGD:13792537 NCBI chr12:9,635,009...9,726,520
Ensembl chr12:9,635,025...9,726,519
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 involved_in ISO
IBA
(PMID:19122240)
PMID:21873635
RGD PMID:19122240 PMID:21873635 RGD:13792537 NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:15781469) RGD PMID:15781469 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) RGD PMID:18762808 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (MGI:3628833|PMID:16601693) RGD PMID:16601693 MGI:3628833 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19504
    signaling 7464
      signal transduction 6884
        cell surface receptor signaling pathway 2780
          enzyme linked receptor protein signaling pathway 978
            transmembrane receptor protein serine/threonine kinase signaling pathway 391
              ubiquitin-dependent SMAD protein catabolic process 6
Path 2
Term Annotations click to browse term
  biological_process 19504
    metabolic process 11814
      organic substance metabolic process 11356
        macromolecule metabolic process 9809
          macromolecule catabolic process 1360
            cellular macromolecule catabolic process 1146
              cellular protein catabolic process 840
                proteolysis involved in cellular protein catabolic process 783
                  modification-dependent protein catabolic process 659
                    ubiquitin-dependent protein catabolic process 643
                      ubiquitin-dependent SMAD protein catabolic process 6
paths to the root