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ONTOLOGY REPORT - ANNOTATIONS

Term:collagen catabolic process
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Accession:GO:0030574 term browser browse the term
Definition:The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
Synonyms:exact_synonym: collagen breakdown;   collagen catabolism;   collagen degradation


show annotations for term's descendants           Sort by:
collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSB cathepsin B involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G CTSK cathepsin K acts_upstream_of_or_within
involved_in		 ISO (PMID:19834056)
(PMID:22952693)		 MGI
BHF-UCL		 PMID:19834056 PMID:22952693 NCBI chr 4:98,389,459...98,404,969
Ensembl chr 4:98,391,428...98,404,961 		JBrowse link
G CTSL cathepsin L involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618 		JBrowse link
G CTSS cathepsin S involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,417,883...98,442,950 		JBrowse link
G CTSV cathepsin V involved_in ISS UniProt GO_REF:0000024 NCBI chr10:25,202,360...25,208,058
Ensembl chr10:25,202,389...25,209,210 		JBrowse link
G MMP1 matrix metallopeptidase 1 involved_in IEA
IBA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076 		JBrowse link
G MMP11 matrix metallopeptidase 11 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:18622425) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:18622425 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:49,907,684...49,917,494
Ensembl chr14:49,907,687...49,912,617 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:33,473,625...33,483,630
Ensembl chr 9:33,473,093...33,483,679 		JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15563592) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:15563592 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:18022611) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:18022611 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928 		JBrowse link
G MMP15 matrix metallopeptidase 15 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:19,890,867...19,912,941
Ensembl chr 6:19,891,107...19,912,913 		JBrowse link
G MMP16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:18022611) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:18022611 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:48,556,826...48,867,959
Ensembl chr 4:48,556,967...48,862,985 		JBrowse link
G MMP17 matrix metallopeptidase 17 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr14:23,481,220...23,506,936
Ensembl chr14:23,481,227...23,506,919 		JBrowse link
G MMP19 matrix metallopeptidase 19 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:21,279,514...21,285,943
Ensembl chr 5:21,280,130...21,285,774 		JBrowse link
G MMP2 matrix metallopeptidase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17440987) RGD
MGI
TreeGrafter
Ensembl
UniProt		 PMID:17440987 PMID:22410640 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:7207278 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MMP20 matrix metallopeptidase 20 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:33,261,448...33,308,047
Ensembl chr 9:33,261,443...33,308,047 		JBrowse link
G MMP23 matrix metallopeptidase 23 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:63,801,668...63,804,275
Ensembl chr 6:63,801,965...63,805,046 		JBrowse link
G MMP24 matrix metallopeptidase 24 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:38,587,230...38,636,628
Ensembl chr17:38,588,081...38,636,627 		JBrowse link
G MMP25 matrix metallopeptidase 25 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:39,129,452...39,143,621
Ensembl chr 3:39,130,777...39,142,303 		JBrowse link
G MMP27 matrix metallopeptidase 27 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:33,366,342...33,379,828
Ensembl chr 9:33,366,345...33,379,789 		JBrowse link
G MMP28 matrix metallopeptidase 28 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr12:39,739,074...39,766,794
Ensembl chr12:39,739,630...39,766,791 		JBrowse link
G MMP3 matrix metallopeptidase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:33,446,969...33,453,995
Ensembl chr 9:33,446,836...33,454,000 		JBrowse link
G MMP7 matrix metallopeptidase 7 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:33,214,590...33,225,080
Ensembl chr 9:33,214,594...33,225,080 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:33,384,034...33,397,637
Ensembl chr 9:33,384,033...33,396,947 		JBrowse link
G MMP9 matrix metallopeptidase 9 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:9291580) RGD
MGI
GO_Central
TreeGrafter
Ensembl
UniProt		 PMID:9291580 PMID:22410640 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:7207278 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MRC2 mannose receptor C type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,059,759...16,119,571
Ensembl chr12:16,059,768...16,119,571 		JBrowse link
G PRSS2 serine protease 2 involved_in ISO (PMID:16192646)
(PMID:12731883)		 UniProt PMID:12731883 PMID:16192646 NCBI chr18:7,443,327...7,446,625
Ensembl chr18:7,443,327...7,446,625 		JBrowse link
G RETREG1 reticulophagy regulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:34338405) Ensembl
MGI		 PMID:34338405 GO_REF:0000107 NCBI chr16:5,726,493...5,879,461
Ensembl chr16:5,726,494...5,879,714 		JBrowse link
G RETREG2 reticulophagy regulator family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:34338405) Ensembl
MGI		 PMID:34338405 GO_REF:0000107 NCBI chr15:121,212,370...121,218,796
Ensembl chr15:121,212,881...121,218,812 		JBrowse link
G RETREG3 reticulophagy regulator family member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:34338405) Ensembl
MGI		 PMID:34338405 GO_REF:0000107 NCBI chr12:20,220,993...20,243,299
Ensembl chr12:20,179,078...20,243,293 		JBrowse link
negative regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590 		JBrowse link
positive regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IDUA alpha-L-iduronidase acts_upstream_of_or_within ISO (PMID:19834056) MGI PMID:19834056 NCBI chr 8:334,604...351,970
Ensembl chr 8:334,617...351,969 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in ISO (PMID:20666777) UniProt PMID:20666777 NCBI chr14:74,667,081...74,693,347
Ensembl chr14:74,666,624...74,693,281 		JBrowse link
regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAP fibroblast activation protein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,831,281...68,902,416
Ensembl chr15:68,830,730...68,902,379 		JBrowse link
G ITGB1 integrin subunit beta 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      collagen metabolic process 126
        collagen catabolic process 35
          negative regulation of collagen catabolic process 1
          positive regulation of collagen catabolic process 2
          regulation of collagen catabolic process + 5
paths to the root