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ONTOLOGY REPORT - ANNOTATIONS


Term:collagen catabolic process
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Accession:GO:0030574 term browser browse the term
Definition:The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
Synonyms:exact_synonym: collagen breakdown;   collagen catabolism;   collagen degradation



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collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 3:89,246,947...89,257,589
Ensembl chr 3:89,245,849...89,257,303
JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif 2 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr11:50,492,912...50,698,400
Ensembl chr11:50,492,911...50,698,400
JBrowse link
G Ctsb cathepsin B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
JBrowse link
G Ctsk cathepsin K involved_in
acts_upstream_of_or_within
ISO
IMP
(PMID:19834056) MGI PMID:19834056 GO_REF:0000119 MGI:4834177 NCBI chr 3:95,406,521...95,416,698
Ensembl chr 3:95,406,567...95,416,673
JBrowse link
G Ctsl cathepsin L involved_in IDA (MGI:6437015|PMID:10716919) UniProt PMID:10716919 MGI:6437015 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
JBrowse link
G Ctss cathepsin S involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
JBrowse link
G Mmp10 matrix metallopeptidase 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241
JBrowse link
G Mmp11 matrix metallopeptidase 11 acts_upstream_of_or_within
involved_in
IDA
IBA
(PMID:18622425) MGI
GO_Central
PMID:18622425 GO_REF:0000033 NCBI chr10:75,759,056...75,768,336
Ensembl chr10:75,759,056...75,772,330
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499
JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in
acts_upstream_of_or_within
IMP
IBA
IDA
ISO
(MGI:3771509|PMID:17987127)
(PMID:15563592)
UniProt
GO_Central
MGI
PMID:15563592 PMID:17987127 GO_REF:0000033 GO_REF:0000119 MGI:3771509 MGI:4834177 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) involved_in
acts_upstream_of_or_within
IBA
IGI
(PMID:18022611) GO_Central
MGI
PMID:18022611 GO_REF:0000033 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821
JBrowse link
G Mmp15 matrix metallopeptidase 15 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:96,078,924...96,100,921
Ensembl chr 8:96,078,896...96,101,708
JBrowse link
G Mmp16 matrix metallopeptidase 16 acts_upstream_of_or_within
involved_in
IGI
IBA
IDA
(PMID:18022611) MGI
GO_Central
PMID:18022611 GO_REF:0000033 NCBI chr 4:17,853,072...18,117,479
Ensembl chr 4:17,852,893...18,119,145
JBrowse link
G Mmp17 matrix metallopeptidase 17 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:129,661,215...129,688,163
Ensembl chr 5:129,661,233...129,688,163
JBrowse link
G Mmp19 matrix metallopeptidase 19 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:128,626,779...128,636,696
Ensembl chr10:128,626,779...128,636,693
JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,464,141...7,476,870
Ensembl chr 9:7,464,141...7,476,857
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 involved_in
acts_upstream_of_or_within
ISO
IMP
IBA
(PMID:17440987) RGD
MGI
GO_Central
PMID:17440987 PMID:22410640 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:7207278 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp20 matrix metallopeptidase 20 (enamelysin) involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,628,232...7,674,969
Ensembl chr 9:7,628,232...7,674,980
JBrowse link
G Mmp21 matrix metallopeptidase 21 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:133,275,999...133,281,790
Ensembl chr 7:133,275,999...133,281,790
JBrowse link
G Mmp23 matrix metallopeptidase 23 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:155,735,111...155,738,982
Ensembl chr 4:155,735,112...155,737,841
JBrowse link
G Mmp24 matrix metallopeptidase 24 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:155,617,262...155,660,286
Ensembl chr 2:155,617,262...155,660,286
JBrowse link
G Mmp25 matrix metallopeptidase 25 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:23,847,289...23,864,006
Ensembl chr17:23,847,285...23,864,251
JBrowse link
G Mmp27 matrix metallopeptidase 27 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,571,397...7,581,886
Ensembl chr 9:7,571,397...7,581,886
JBrowse link
G Mmp28 matrix metallopeptidase 28 (epilysin) involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:83,331,594...83,353,890
Ensembl chr11:83,331,594...83,353,897
JBrowse link
G Mmp3 matrix metallopeptidase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp7 matrix metallopeptidase 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,692,095...7,699,587
Ensembl chr 9:7,692,091...7,699,586
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:7,558,430...7,568,487
Ensembl chr 9:7,558,457...7,568,486
JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in
acts_upstream_of_or_within
ISO
IDA
IBA
(PMID:9291580) RGD
MGI
GO_Central
PMID:9291580 PMID:22410640 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:7207278 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mrc2 mannose receptor, C type 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:105,183,440...105,241,971
Ensembl chr11:105,183,469...105,241,965
JBrowse link
G Pepd peptidase D acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 7:34,611,832...34,744,131
Ensembl chr 7:34,611,804...34,744,133
JBrowse link
G Prss1 serine protease 1 (trypsin 1) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,435,864...41,440,720
Ensembl chr 6:41,435,866...41,440,720
JBrowse link
G Prss1l serine protease 1 (trypsin 1) like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,369,290...41,374,190
Ensembl chr 6:41,369,290...41,374,164
JBrowse link
G Prss2 serine protease 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,498,710...41,502,013
Ensembl chr 6:41,498,721...41,502,013
JBrowse link
G Prss3 serine protease 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,350,693...41,354,547
Ensembl chr 6:41,350,748...41,354,612
JBrowse link
G Prss3l serine protease 3 like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,419,150...41,438,162
Ensembl chr 6:41,419,150...41,423,079
JBrowse link
G Prtn3 proteinase 3 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr10:79,715,499...79,719,008
Ensembl chr10:79,710,310...79,719,008
JBrowse link
G Retreg1 reticulophagy regulator 1 acts_upstream_of_or_within IMP (PMID:34338405) MGI PMID:34338405 NCBI chr15:25,840,795...25,973,782
Ensembl chr15:25,843,266...25,973,773
JBrowse link
G Retreg2 reticulophagy regulator family member 2 acts_upstream_of_or_within IMP (PMID:34338405) MGI PMID:34338405 NCBI chr 1:75,119,432...75,124,553
Ensembl chr 1:75,119,422...75,124,557
JBrowse link
G Retreg3 reticulophagy regulator family member 3 acts_upstream_of_or_within IMP (PMID:34338405) MGI PMID:34338405 NCBI chr11:100,987,148...101,010,720
Ensembl chr11:100,987,148...101,010,719
JBrowse link
G Try10 trypsin 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,331,039...41,334,878
Ensembl chr 6:41,331,039...41,334,848
JBrowse link
G Try4 trypsin 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,279,206...41,282,467
Ensembl chr 6:41,279,203...41,282,466
JBrowse link
G Try5 trypsin 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:41,288,166...41,291,644
Ensembl chr 6:41,288,167...41,293,775
JBrowse link
negative regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612
JBrowse link
positive regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua iduronidase, alpha-L acts_upstream_of_or_within IMP (PMID:19834056) MGI PMID:19834056 NCBI chr 5:108,808,197...108,833,312
Ensembl chr 5:108,808,197...108,832,423
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:60,182,630...60,266,073
Ensembl chr10:60,182,630...60,208,463
JBrowse link
regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fap fibroblast activation protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:62,331,280...62,404,365
Ensembl chr 2:62,331,287...62,404,419
JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    metabolic process 11001
      collagen metabolic process 139
        collagen catabolic process 48
          negative regulation of collagen catabolic process 1
          positive regulation of collagen catabolic process 2
          regulation of collagen catabolic process + 5
paths to the root