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ONTOLOGY REPORT - ANNOTATIONS


Term:collagen catabolic process
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Accession:GO:0030574 term browser browse the term
Definition:The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
Synonyms:exact_synonym: collagen breakdown;   collagen catabolism;   collagen degradation



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collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07069011.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Adam15 ADAM metallopeptidase domain 15 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:174,754,631...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Ctsb cathepsin B involved_in ISO
IEA
(PMID:22952693)
GO_REF:0000107
RGD
Ensembl
PMID:22952693 GO_REF:0000107 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsk cathepsin K acts_upstream_of_or_within
involved_in
ISO MGI:2182131 (MGI:4397742|PMID:19834056)
(PMID:19834056)
(PMID:22952693)
RGD PMID:19834056 PMID:22952693 MGI:4397742 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Ctsl cathepsin L involved_in ISO
ISS
(PMID:10716919), (PMID:22952693)
(MGI:6437015|PMID:10716919)
GO_REF:0000024
RGD
UniProt
PMID:10716919 PMID:22952693 GO_REF:0000024 MGI:6437015 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Ctss cathepsin S involved_in IEA
ISO
GO_REF:0000107
(PMID:22952693)
Ensembl
RGD
PMID:22952693 GO_REF:0000107 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Mmp1 matrix metallopeptidase 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp10 matrix metallopeptidase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp11 matrix metallopeptidase 11 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3822602|PMID:18622425)
RGD PMID:18622425 PMID:21873635 MGI:3822602, RGD:13792537 NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628
JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in
acts_upstream_of_or_within
IBA
IEA
ISO
ISS
PMID:21873635
GO_REF:0000107
(MGI:3513736|PMID:15563592)
(MGI:3771509|PMID:17987127)
GO_REF:0000024
(PMID:8576151), (PMID:9065415)
Ensembl
RGD
UniProt
PMID:8576151 PMID:9065415 PMID:15563592 PMID:17987127 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:3513736 MGI:3771509, RGD:13792537 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1276107 (MGI:3771253|PMID:18022611)
RGD PMID:18022611 PMID:21873635 MGI:3771253, RGD:13792537 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp15 matrix metallopeptidase 15 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mmp16 matrix metallopeptidase 16 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:101900 (MGI:3771253|PMID:18022611)
GO_REF:0000107
RGD
Ensembl
PMID:18022611 PMID:21873635 GO_REF:0000107 MGI:3771253, RGD:13792537 NCBI chr 5:31,312,280...31,556,276
Ensembl chr 5:31,312,280...31,548,388
JBrowse link
G Mmp17 matrix metallopeptidase 17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:27,074,398...27,099,317
Ensembl chr12:27,074,409...27,099,316
JBrowse link
G Mmp19 matrix metallopeptidase 19 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,598,326...4,606,965
Ensembl chr 8:4,598,391...4,606,965
JBrowse link
G Mmp2 matrix metallopeptidase 2 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
IEA
MGI:2386252 (MGI:3710444|PMID:17440987)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:17440987 PMID:22410640 PMID:21873635 GO_REF:0000107 MGI:3710444, RGD:7207278, RGD:13792537 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp20 matrix metallopeptidase 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,789,415...4,830,035
Ensembl chr 8:4,789,415...4,830,035
JBrowse link
G Mmp21 matrix metallopeptidase 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:188,480,186...188,485,855
Ensembl chr 1:188,480,186...188,485,855
JBrowse link
G Mmp23 matrix metallopeptidase 23 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433
JBrowse link
G Mmp24 matrix metallopeptidase 24 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:144,279,096...144,323,572
Ensembl chr 3:144,279,096...144,323,572
JBrowse link
G Mmp27 matrix metallopeptidase 27 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,745,887...4,755,806
Ensembl chr 8:4,745,883...4,755,806
JBrowse link
G Mmp28 matrix metallopeptidase 28 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:68,243,748...68,264,728
Ensembl chr10:68,241,138...68,264,866
JBrowse link
G Mmp3 matrix metallopeptidase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp7 matrix metallopeptidase 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp8 matrix metallopeptidase 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:4,724,009...4,732,956
Ensembl chr 8:4,724,029...4,733,520
JBrowse link
G Mmp9 matrix metallopeptidase 9 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
IBA
(MGI:1096214|PMID:9291580)
GO_REF:0000107
PMID:21873635
GO_REF:0000043
RGD
Ensembl
UniProt
PMID:9291580 PMID:22410640 PMID:21873635 GO_REF:0000043 GO_REF:0000107 MGI:1096214, RGD:7207278, RGD:13792537 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrc2 mannose receptor, C type 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:12972549)
Ensembl
RGD
PMID:12972549 GO_REF:0000107 NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856
JBrowse link
G Pepd peptidase D involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:87,536,650...87,681,233 JBrowse link
G Prss2 protease, serine, 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:70,278,304...70,283,385
Ensembl chr 4:70,278,304...70,283,385
JBrowse link
negative regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
positive regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within ISO MGI:2176236 (MGI:4397742|PMID:19834056) RGD PMID:19834056 MGI:4397742 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:20666777) RGD PMID:20666777 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
regulation of collagen catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fap fibroblast activation protein, alpha involved_in ISO (PMID:10455171) RGD PMID:10455171 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545
JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:10455171)
UniProt
Ensembl
RGD
PMID:10455171 GO_REF:0000024 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      collagen metabolic process 115
        collagen catabolic process 36
          negative regulation of collagen catabolic process 1
          positive regulation of collagen catabolic process 2
          regulation of collagen catabolic process + 5
paths to the root