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ONTOLOGY REPORT - ANNOTATIONS

Term:cAMP binding
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Accession:GO:0030552 term browser browse the term
Definition:Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
Synonyms:exact_synonym: 3',5' cAMP binding;   adenosine 3',5'-cyclophosphate binding;   cyclic AMP binding
 xref: Reactome:R-HSA-111925 "cAMP induces dissociation of inactive PKA tetramers";   Reactome:R-HSA-381608 "cAMP activates EPAC2";   Reactome:R-HSA-381668 "cAMP activates EPAC1";   Reactome:R-HSA-381707 "PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP"

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cAMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bves blood vessel epicardial substance enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936564:1,791,733...1,823,421
Ensembl chrNW_004936564:1,788,317...1,823,084 		JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936561:4,891,801...4,953,614
Ensembl chrNW_004936561:4,901,253...4,941,053 		JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936482:14,091,343...14,107,793
Ensembl chrNW_004936482:14,091,913...14,107,787 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 enables ISO (PMID:34699778) UniProt PMID:34699778 NCBI chrNW_004936475:9,844,438...9,908,009 JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 enables IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chrNW_004936480:17,051,902...17,416,335
Ensembl chrNW_004936480:17,051,898...17,413,657 		JBrowse link
G Hcn3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 enables IEA UniProt GO_REF:0000043 NCBI chrNW_004936580:4,760,289...4,770,571
Ensembl chrNW_004936580:4,760,241...4,772,583 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 enables IEA UniProt GO_REF:0000043 NCBI chrNW_004936471:32,527,551...32,570,548
Ensembl chrNW_004936471:32,529,847...32,570,284 		JBrowse link
G LOC101954919 cAMP-dependent protein kinase type I-alpha regulatory subunit-like enables IEA UniProt GO_REF:0000043 NCBI chrNW_004936534:2,622,329...2,623,615 JBrowse link
G LOC101973720 rap guanine nucleotide exchange factor 3 ISO RGD PMID:16244178 RGD:9850088 NCBI chrNW_004936512:5,636,197...5,659,606
Ensembl chrNW_004936512:5,636,758...5,659,300
Ensembl chrNW_004936512:5,636,758...5,659,300 		JBrowse link
G Pde10a phosphodiesterase 10A enables ISO (PMID:19689430) UniProt PMID:19689430 NCBI chrNW_004936489:15,401,248...15,671,594
Ensembl chrNW_004936489:15,400,629...15,671,600 		JBrowse link
G Pde1c phosphodiesterase 1C ISO RGD PMID:7568196 RGD:68318 NCBI chrNW_004936478:7,900,432...8,499,300
Ensembl chrNW_004936478:7,900,432...8,393,631 		JBrowse link
G Pde2a phosphodiesterase 2A enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936498:1,856,256...1,944,405
Ensembl chrNW_004936498:1,856,144...1,944,412 		JBrowse link
G Pde4a phosphodiesterase 4A enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936659:742,969...770,473
Ensembl chrNW_004936659:732,893...768,620 		JBrowse link
G Pde4b phosphodiesterase 4B enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936591:5,152,491...5,666,728
Ensembl chrNW_004936591:5,152,441...5,573,129 		JBrowse link
G Pde4d phosphodiesterase 4D enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936480:8,123,437...9,235,586
Ensembl chrNW_004936480:8,204,701...9,234,865 		JBrowse link
G Popdc2 popeye domain containing 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936536:6,562,583...6,582,407
Ensembl chrNW_004936536:6,560,329...6,582,331 		JBrowse link
G Popdc3 popeye domain containing 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936564:1,840,270...1,860,894
Ensembl chrNW_004936564:1,840,458...1,843,492 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha enables ISO
IEA		 RGD
UniProt		 PMID:11907174 GO_REF:0000043 RGD:2312572 NCBI chrNW_004936541:7,845,876...7,863,677
Ensembl chrNW_004936541:7,845,676...7,863,709 		JBrowse link
G Prkar1b protein kinase cAMP-dependent type I regulatory subunit beta enables ISO
IEA		 RGD
TreeGrafter
UniProt		 PMID:11907174 GO_REF:0000043 GO_REF:0000118 RGD:2312572 NCBI chrNW_004936754:842,697...963,002
Ensembl chrNW_004936754:842,343...963,024 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha enables ISO
IEA		 RGD
TreeGrafter
UniProt		 PMID:11907174 GO_REF:0000043 GO_REF:0000118 RGD:2312572 NCBI chrNW_004936529:528,138...601,078
Ensembl chrNW_004936529:528,114...601,122 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta enables ISO
IEA		 RGD
TreeGrafter
UniProt		 PMID:11907174 PMID:14625280 GO_REF:0000043 GO_REF:0000118 RGD:2312570 RGD:2312572 NCBI chrNW_004936479:16,894,068...16,988,879
Ensembl chrNW_004936479:16,894,068...16,988,885 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 NOT|enables ISO (PMID:10548487), (PMID:10608844), (PMID:11359771)
(PMID:10801446)		 UniProt PMID:10548487 PMID:10608844 PMID:10801446 PMID:11359771 NCBI chrNW_004936576:5,583,847...5,746,583
Ensembl chrNW_004936576:5,583,805...5,746,671 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 enables ISO
IEA		 RGD
Ensembl		 PMID:9856955 GO_REF:0000107 RGD:632397 NCBI chrNW_004936509:2,722,279...3,006,436
Ensembl chrNW_004936509:2,722,428...3,005,288 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17092
    binding 15355
      small molecule binding 4970
        ion binding 4762
          anion binding 2196
            cAMP binding 23
Path 2
Term Annotations click to browse term
  molecular_function 17092
    binding 15355
      organic cyclic compound binding 4944
        nucleoside phosphate binding 1938
          nucleotide binding 1938
            purine nucleotide binding 1793
              purine ribonucleotide binding 1678
                adenyl ribonucleotide binding 1350
                  cAMP binding 23
paths to the root