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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:androgen receptor signaling pathway
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Accession:GO:0030521 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
Synonyms:exact_synonym: androgen receptor signalling pathway

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androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Andpro androgen regulated protein IMP RGD PMID:8262963 RGD:1566559 NCBI chr 3:143,893,005...143,899,609
Ensembl chr 3:143,893,006...143,899,370 		JBrowse link
G Ar androgen receptor NOT IMP
ISO		 (PMID:10428808), (PMID:19886863), (PMID:20048160)
(MGI:MGI:3047515|PMID:15199138), (MGI:MGI:3529739|PMID:15660130), (MGI:MGI:5882884|PMID:18761815)
(PMID:19244107)		 RGD PMID:10428808, PMID:15199138, PMID:15660130, PMID:18761815, PMID:19244107, PMID:19886863, PMID:20048160, PMID:2341409 MGI:MGI:3047515, MGI:MGI:3529739, MGI:MGI:5882884, RGD:1298681 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Arid1a AT-rich interaction domain 1A ISO (PMID:12200431) RGD PMID:12200431 NCBI chr 5:151,904,687...151,977,973
Ensembl chr 5:151,904,684...151,977,636 		JBrowse link
G Cst11 cystatin 11 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:143,096,056...143,098,780
Ensembl chr 3:143,096,056...143,098,780 		JBrowse link
G Daxx death-domain associated protein ISO
IEA		 (PMID:15572661)
GO_REF:0000107		 RGD
Ensembl		 PMID:15572661 GO_REF:0000107 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926 		JBrowse link
G Ddx17 DEAD-box helicase 17 ISO (PMID:24275493) RGD PMID:24275493 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641 		JBrowse link
G Ddx5 DEAD-box helicase 5 ISO (PMID:24275493) RGD PMID:24275493 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 ISO MGI:MGI:3573790 (MGI:MGI:3529739|PMID:15660130) RGD PMID:15660130 MGI:MGI:3529739 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 ISO MGI:MGI:3690438 (MGI:MGI:3708425|PMID:17142810) RGD PMID:17142810 MGI:MGI:3708425 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447 		JBrowse link
G Kdm3a lysine demethylase 3A IEA
ISO		 GO_REF:0000107
(PMID:16603237)		 Ensembl
RGD		 PMID:16603237 GO_REF:0000107 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905 		JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO
ISS		 (PMID:19886863)
GO_REF:0000024		 RGD
UniProt		 PMID:19886863 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 IMP RGD PMID:9920921 RGD:70792 NCBI chr18:73,479,863...73,524,956
Ensembl chr18:73,378,662...73,524,956 		JBrowse link
G Rhoa ras homolog family member A ISO (MGI:MGI:3616918|PMID:16254014) RGD PMID:16254014 MGI:MGI:3616918 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167 		JBrowse link
G Rwdd1 RWD domain containing 1 ISO (MGI:MGI:5882884|PMID:18761815) RGD PMID:18761815 MGI:MGI:5882884 NCBI chr20:27,534,361...27,552,225
Ensembl chr20:27,535,324...27,552,349 		JBrowse link
G Scgb2a1 secretoglobin, family 2A, member 1 ISO
IBA		 (PMID:16020486)
PMID:21873635		 RGD PMID:16020486, PMID:21873635 RGD:13792537 NCBI chr 1:225,899,313...225,902,676
Ensembl chr 1:225,899,313...225,902,676 		JBrowse link
G Scgb2a2 secretoglobin, family 2A, member 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:225,825,419...225,830,374
Ensembl chr 1:225,825,356...225,830,355
Ensembl chr 1:225,825,356...225,830,355 		JBrowse link
G Tmf1 TATA element modulatory factor 1 ISO
IEA		 (PMID:10428808)
GO_REF:0000107		 RGD
Ensembl		 PMID:10428808 GO_REF:0000107 NCBI chr 4:129,521,986...129,546,024
Ensembl chr 4:129,521,991...129,544,506 		JBrowse link
G Ube3a ubiquitin protein ligase E3A ISO PR:P19091 (MGI:MGI:3616918|PMID:16254014) RGD PMID:16254014 MGI:MGI:3616918 NCBI chr 1:116,586,901...116,678,161
Ensembl chr 1:116,587,815...116,679,973 		JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 ISO (PMID:14609956) RGD PMID:14609956 NCBI chr16:1,749,191...1,954,633
Ensembl chr16:1,749,191...1,954,614 		JBrowse link
activation of prostate induction by androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO
IEA		 MGI:MGI:3716756 (MGI:MGI:3714080|PMID:17317769)
GO_REF:0000107		 RGD
Ensembl		 PMID:17317769 GO_REF:0000107, MGI:MGI:3714080 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
negative regulation of androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2 DAB adaptor protein 2 IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270 		JBrowse link
G Esr2 estrogen receptor 2 ISO MGI:MGI:2152217 (MGI:MGI:3761900|PMID:12370428) RGD PMID:12370428 MGI:MGI:3761900 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Foxh1 forkhead box H1 ISO (PMID:16120611) RGD PMID:16120611 NCBI chr 7:117,730,307...117,733,076
Ensembl chr 7:117,730,307...117,732,387 		JBrowse link
G Foxp1 forkhead box P1 ISO (PMID:18640093) RGD PMID:18640093 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755 		JBrowse link
G Hdac1 histone deacetylase 1 ISO (PMID:15919722) RGD PMID:15919722 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like ISO (PMID:21454491) RGD PMID:21454491 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO MGI:MGI:2152423 (MGI:MGI:3822220|PMID:18827067) RGD PMID:18827067 MGI:MGI:3822220 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 IEA
ISO		 GO_REF:0000107
(PMID:20812024)		 Ensembl
RGD		 PMID:20812024 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO (PMID:20812024) RGD PMID:20812024 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701 		JBrowse link
G Nodal nodal growth differentiation factor ISO (PMID:21656830) RGD PMID:21656830 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096 		JBrowse link
G Phb prohibitin ISO (PMID:16964284), (PMID:18487222) RGD PMID:16964284, PMID:18487222 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 IEA
ISO		 GO_REF:0000107
(PMID:11477070)		 Ensembl
RGD		 PMID:11477070 GO_REF:0000107 NCBI chr18:73,479,863...73,524,956
Ensembl chr18:73,378,662...73,524,956 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 IEA
ISO		 GO_REF:0000107
(PMID:19277043)		 Ensembl
RGD		 PMID:19277043 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777 		JBrowse link
G Sirt1 sirtuin 1 ISO
IEA		 (PMID:17505061)
GO_REF:0000107		 RGD
Ensembl		 PMID:17505061 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO
IEA		 (PMID:18487222)
GO_REF:0000107		 RGD
Ensembl		 PMID:18487222 GO_REF:0000107 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468 		JBrowse link
G Tcf21 transcription factor 21 ISO
ISS		 (MGI:MGI:3588448|PMID:15919722)
GO_REF:0000024		 RGD
UniProt		 PMID:15919722 GO_REF:0000024, MGI:MGI:3588448 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566 		JBrowse link
G Zbtb7a zinc finger and BTB domain containing 7a ISS
ISO
IEA		 GO_REF:0000024
(PMID:20812024)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20812024 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:11,429,266...11,446,119
Ensembl chr 7:11,432,049...11,444,786 		JBrowse link
regulation of androgen receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 ISO (PMID:19372219) RGD PMID:19372219 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134 		JBrowse link
G Ddx5 DEAD-box helicase 5 ISO (PMID:18829551) RGD PMID:18829551 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461 		JBrowse link
G Ep300 E1A binding protein p300 ISO (PMID:18487222) RGD PMID:18487222 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296 		JBrowse link
G Kdm5d lysine demethylase 5D ISO (PMID:27185910) RGD PMID:27185910 NCBI chr  Y:501,058...589,267
Ensembl chr  Y:505,996...589,267 		JBrowse link
G Park7 Parkinsonism associated deglycase ISO
IEA
ISS		 (PMID:11477070)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:11477070 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724 		JBrowse link
G Pias2 protein inhibitor of activated STAT, 2 IDA PMID:9920921 MGI PMID:9920921 RGD:70792 NCBI chr18:73,479,863...73,524,956
Ensembl chr18:73,378,662...73,524,956 		JBrowse link
G Prmt2 protein arginine methyltransferase 2 ISO (PMID:17587566) RGD PMID:17587566 NCBI chr20:13,154,513...13,212,613
Ensembl chr20:13,156,241...13,212,606 		JBrowse link
G Rnf14 ring finger protein 14 ISO (PMID:19345326) RGD PMID:19345326 NCBI chr18:31,443,424...31,468,641
Ensembl chr18:31,444,472...31,468,640 		JBrowse link
G Rnf6 ring finger protein 6 ISO (PMID:19345326) RGD PMID:19345326 NCBI chr12:10,574,168...10,583,196
Ensembl chr12:10,574,168...10,583,208 		JBrowse link
G Safb2 scaffold attachment factor B2 ISO
IBA		 MGI:MGI:5695073 (MGI:MGI:5693455|PMID:26092125)
PMID:21873635		 RGD PMID:26092125, PMID:21873635 MGI:MGI:5693455, RGD:13792537 NCBI chr 9:10,471,618...10,492,775
Ensembl chr 9:10,471,742...10,490,416 		JBrowse link
G Trim68 tripartite motif containing 68 ISO (PMID:18451177) RGD PMID:18451177 NCBI chr 1:167,835,773...167,849,880
Ensembl chr 1:167,835,647...167,849,834 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      signal transduction 7015
        intracellular receptor signaling pathway 255
          intracellular steroid hormone receptor signaling pathway 113
            androgen receptor signaling pathway 44
              activation of prostate induction by androgen receptor signaling pathway 1
              negative regulation of androgen receptor signaling pathway 17
              negative regulation of mammary gland development in males by androgen receptor signaling pathway 0
              regulation of androgen receptor signaling pathway + 27
Path 2
Term Annotations click to browse term
  biological_process 20014
    response to stimulus 10568
      cellular response to stimulus 8906
        cellular response to chemical stimulus 3517
          cellular response to organic substance 2836
            cellular response to hormone stimulus 757
              hormone-mediated signaling pathway 186
                steroid hormone mediated signaling pathway 132
                  intracellular steroid hormone receptor signaling pathway 113
                    androgen receptor signaling pathway 44
                      activation of prostate induction by androgen receptor signaling pathway 1
                      negative regulation of androgen receptor signaling pathway 17
                      negative regulation of mammary gland development in males by androgen receptor signaling pathway 0
                      regulation of androgen receptor signaling pathway + 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.