Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:BMP signaling pathway
go back to main search page
Accession:GO:0030509 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: BMP signalling pathway;   bone morphogenetic protein signaling pathway;   bone morphogenetic protein signalling pathway
 narrow_synonym: decapentaplegic receptor signaling pathway;   decapentaplegic receptor signalling pathway;   decapentaplegic signaling pathway;   dpp receptor signaling pathway;   dpp receptor signalling pathway;   dpp signaling pathway
 related_synonym: BMP receptor signaling pathway
 alt_id: GO:0008101


show annotations for term's descendants           Sort by:
 
BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 IDA
IBA
(PMID:18436533)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:18436533, PMID:21873635 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,444...157,876,330
Ensembl chr 2:157,736,444...157,876,330
JBrowse link
G ACVR2A activin A receptor type 2A IDA
IMP
TAS
(PMID:18436533)
(PMID:17472960), (PMID:19366699)
BHF-UCL
MGI
Reactome
PMID:17472960, PMID:18436533, PMID:19366699 Reactome:R-HSA-201451 NCBI chr 2:147,844,517...147,930,822
Ensembl chr 2:147,844,517...147,930,826
JBrowse link
G ACVR2B activin A receptor type 2B IDA
TAS
IMP
(PMID:18436533)
(PMID:19903896)
BHF-UCL
Reactome
PMID:18436533, PMID:19903896 Reactome:R-HSA-201451 NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142
JBrowse link
G ACVRL1 activin A receptor like type 1 IMP
IBA
TAS
(PMID:19366699)
(PMID:21873635)
BHF-UCL
GO_Central
Reactome
PMID:19366699, PMID:21873635 Reactome:R-HSA-201451 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G AMH anti-Mullerian hormone TAS Reactome Reactome:R-HSA-201451 NCBI chr19:2,249,323...2,252,073
Ensembl chr19:2,249,309...2,252,073
JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 TAS Reactome Reactome:R-HSA-201451 NCBI chr12:53,423,855...53,431,672
Ensembl chr12:53,423,855...53,431,672
JBrowse link
G BMP10 bone morphogenetic protein 10 TAS
IDA
(PMID:16049014), (PMID:17068149) Reactome
BHF-UCL
PMID:16049014, PMID:17068149 Reactome:R-HSA-201451 NCBI chr 2:68,860,909...68,871,397
Ensembl chr 2:68,860,909...68,871,397
JBrowse link
G BMP15 bone morphogenetic protein 15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:50,910,735...50,916,641
Ensembl chr  X:50,910,735...50,916,641
Ensembl chr  X:50,910,735...50,916,641
JBrowse link
G BMP2 bone morphogenetic protein 2 IEP
IBA
IDA
IMP
IGI
TAS
(PMID:16194878)
(PMID:21873635)
(PMID:16049014), (PMID:18436533), (PMID:20843790)
(PMID:17472960), (PMID:18326817), (PMID:19664780)
(PMID:22450430)
AgBase
GO_Central
BHF-UCL
MGI
Reactome
PMID:16049014, PMID:16194878, PMID:17472960, PMID:18326817, PMID:18436533, PMID:19664780, PMID:20843790, PMID:21873635, PMID:22450430 Reactome:R-HSA-201451 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
JBrowse link
G BMP4 bone morphogenetic protein 4 IDA
IMP
(PMID:18436533), (PMID:9389648)
(PMID:17472960), (PMID:18326817)
BHF-UCL
MGI
PMID:9389648, PMID:17472960, PMID:18326817, PMID:18436533 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMP5 bone morphogenetic protein 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590
JBrowse link
G BMP6 bone morphogenetic protein 6 IDA
IBA
ISS
IMP
(PMID:18436533)
(PMID:21873635)
(PMID:18326817)
BHF-UCL
GO_Central
PMID:18326817, PMID:18436533, PMID:21873635 GO_REF:0000024 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
JBrowse link
G BMP7 bone morphogenetic protein 7 IMP
IBA
IDA
(PMID:18326817)
(PMID:21873635)
(PMID:16049014), (PMID:18436533)
BHF-UCL
GO_Central
PMID:16049014, PMID:18326817, PMID:18436533, PMID:21873635 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
JBrowse link
G BMP8A bone morphogenetic protein 8a IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:39,491,626...39,529,869
Ensembl chr 1:39,491,636...39,529,869
JBrowse link
G BMP8B bone morphogenetic protein 8b IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:39,757,182...39,788,865
Ensembl chr 1:39,757,182...39,788,865
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A IC
IBA
IDA
TAS
(PMID:24904118)
(PMID:21873635)
(PMID:18436533), (PMID:9389648)
BHF-UCL
GO_Central
Reactome
PMID:9389648, PMID:18436533, PMID:21873635, PMID:24904118 Reactome:R-HSA-201451 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,838
Ensembl chr10:86,756,601...86,932,838
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IDA
IBA
NAS
TAS
(PMID:18436533)
(PMID:21873635)
(PMID:10051328)
BHF-UCL
GO_Central
UniProtKB
Reactome
PMID:10051328, PMID:18436533, PMID:21873635 Reactome:R-HSA-201451 NCBI chr 4:94,757,955...95,158,453
Ensembl chr 4:94,757,955...95,158,448
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 IDA
IBA
IMP
ISS
TAS
(PMID:18436533)
(PMID:21873635)
(PMID:12045205), (PMID:19366699), (PMID:9442116)
BHF-UCL
GO_Central
Reactome
PMID:9442116, PMID:12045205, PMID:18436533, PMID:19366699, PMID:21873635 GO_REF:0000024, Reactome:R-HSA-201451 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist TAS Reactome Reactome:R-HSA-201451 NCBI chr 9:14,715,082...14,724,308
Ensembl chr 9:14,719,724...14,722,733
JBrowse link
G CHRDL1 chordin like 1 TAS Reactome Reactome:R-HSA-201451 NCBI chr  X:110,673,856...110,795,817
Ensembl chr  X:110,673,856...110,795,819
JBrowse link
G COMP cartilage oligomeric matrix protein IEA Ensembl GO_REF:0000107 NCBI chr19:18,782,773...18,791,305
Ensembl chr19:18,782,773...18,791,305
JBrowse link
G DDX5 DEAD-box helicase 5 IMP (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr17:64,498,254...64,506,866
Ensembl chr17:64,498,254...64,508,199
JBrowse link
G DLX5 distal-less homeobox 5 ISS BHF-UCL GO_REF:0000024 NCBI chr 7:97,020,396...97,024,831
Ensembl chr 7:97,020,396...97,024,950
JBrowse link
G DSG4 desmoglein 4 IEA Ensembl GO_REF:0000107 NCBI chr18:31,376,777...31,415,791
Ensembl chr18:31,376,777...31,414,912
JBrowse link
G ECSIT ECSIT signaling integrator ISO (MGI:MGI:2682456|PMID:14633973) MGI PMID:14633973 MGI:MGI:2682456 NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172
JBrowse link
G EGR1 early growth response 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
JBrowse link
G ENG endoglin TAS (PMID:11382917) BHF-UCL PMID:11382917 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G EXT1 exostosin glycosyltransferase 1 ISO (MGI:MGI:5487694|PMID:23458899), (MGI:MGI:5907385|PMID:28445472), (MGI:MGI:6406761|PMID:22556407), (MGI:MGI:6406770|PMID:21148566)
(MGI:MGI:6406761|PMID:22556407)
MGI PMID:21148566, PMID:22556407, PMID:23458899, PMID:28445472 MGI:MGI:5487694, MGI:MGI:5907385, MGI:MGI:6406761, MGI:MGI:6406770 NCBI chr 8:117,794,490...118,111,826
Ensembl chr 8:117,794,490...118,111,853
Ensembl chr 8:117,794,490...118,111,853
JBrowse link
G FAM83G family with sequence similarity 83 member G IDA
IBA
(PMID:24554596)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24554596 NCBI chr17:18,968,789...19,006,143
Ensembl chr17:18,968,789...19,004,764
JBrowse link
G FST follistatin IEA Ensembl GO_REF:0000107 NCBI chr 5:53,480,338...53,487,134
Ensembl chr 5:53,480,626...53,487,134
JBrowse link
G FSTL1 follistatin like 1 TAS Reactome Reactome:R-HSA-201451 NCBI chr 3:120,392,293...120,450,993
Ensembl chr 3:120,392,293...120,450,993
JBrowse link
G GDF1 growth differentiation factor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:18,868,545...18,896,158
Ensembl chr19:18,868,545...18,896,158
JBrowse link
G GDF15 growth differentiation factor 15 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:18,382,170...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GDF2 growth differentiation factor 2 TAS
IDA
(PMID:17068149), (PMID:19366699) Reactome
BHF-UCL
PMID:17068149, PMID:19366699 Reactome:R-HSA-201451 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588
JBrowse link
G GDF3 growth differentiation factor 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:7,689,784...7,695,775
Ensembl chr12:7,689,784...7,695,775
JBrowse link
G GDF5 growth differentiation factor 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GDF6 growth differentiation factor 6 IDA (PMID:16049014) BHF-UCL PMID:16049014 NCBI chr 8:96,142,333...96,160,806
Ensembl chr 8:96,142,333...96,160,806
JBrowse link
G GDF7 growth differentiation factor 7 IDA
IBA
(PMID:16049014)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:16049014, PMID:21873635 NCBI chr 2:20,667,144...20,679,243
Ensembl chr 2:20,667,144...20,679,243
JBrowse link
G GDF9 growth differentiation factor 9 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:132,861,181...132,866,884
Ensembl chr 5:132,861,181...132,866,884
JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist TAS Reactome Reactome:R-HSA-201451 NCBI chr 1:240,489,573...240,612,372
Ensembl chr 1:240,489,573...240,612,155
JBrowse link
G HFE homeostatic iron regulator IDA (PMID:24904118) BHF-UCL PMID:24904118 NCBI chr 6:26,087,347...26,098,343
Ensembl chr 6:26,087,281...26,098,343
JBrowse link
G HIVEP1 HIVEP zinc finger 1 IDA (PMID:17008448) FlyBase PMID:17008448 NCBI chr 6:12,002,096...12,212,034
Ensembl chr 6:12,008,762...12,164,999
JBrowse link
G HJV hemojuvelin BMP co-receptor IMP
IBA
IEA
IGI
(PMID:16604073)
(PMID:21873635)
(PMID:18326817)
BHF-UCL
GO_Central
InterPro
PMID:16604073, PMID:18326817, PMID:21873635 GO_REF:0000002 NCBI chr 1:146,017,470...146,021,735
Ensembl chr 1:146,017,468...146,036,746
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein IEA Ensembl GO_REF:0000107 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
JBrowse link
G LEFTY1 left-right determination factor 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:225,886,282...225,889,146
Ensembl chr 1:225,886,282...225,911,382
JBrowse link
G LEFTY2 left-right determination factor 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:225,936,603...225,941,367
Ensembl chr 1:225,936,598...225,941,383
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 IMP (PMID:19664780) BHF-UCL PMID:19664780 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MEGF8 multiple EGF like domains 8 ISS UniProtKB GO_REF:0000024 NCBI chr19:42,325,635...42,378,765
Ensembl chr19:42,325,609...42,378,769
JBrowse link
G MIR122 microRNA 122 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
JBrowse link
G MIR125A microRNA 125a ISO (MGI:MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:MGI:5465045 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339
JBrowse link
G MIR147B microRNA 147b ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr15:45,433,050...45,433,129
Ensembl chr15:45,433,050...45,433,129
JBrowse link
G MIR16-1 microRNA 16-1 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr13:50,048,973...50,049,061
Ensembl chr13:50,048,973...50,049,061
JBrowse link
G MIR210 microRNA 210 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198
JBrowse link
G MIR23A microRNA 23a ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659
JBrowse link
G MIR329-2 microRNA 329-2 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr14:101,027,100...101,027,183
Ensembl chr14:101,027,100...101,027,183
JBrowse link
G MIRLET7A1 microRNA let-7a-1 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr 9:94,175,957...94,176,036
Ensembl chr 9:94,175,957...94,176,036
JBrowse link
G MIRLET7B microRNA let-7b ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr22:46,113,686...46,113,768
Ensembl chr22:46,113,686...46,113,768
JBrowse link
G MIRLET7D microRNA let-7d ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr 9:94,178,834...94,178,920
Ensembl chr 9:94,178,834...94,178,920
JBrowse link
G MIRLET7F1 microRNA let-7f-1 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr 9:94,176,347...94,176,433
Ensembl chr 9:94,176,347...94,176,433
JBrowse link
G MIRLET7F2 microRNA let-7f-2 ISO (MGI:MGI:3851892|PMID:19520079) MGI PMID:19520079 MGI:MGI:3851892 NCBI chr  X:53,557,192...53,557,274
Ensembl chr  X:53,557,192...53,557,274
JBrowse link
G MSX1 msh homeobox 1 ISO (MGI:MGI:3806189|PMID:18590716)
(MGI:MGI:3720542|PMID:17601530)
MGI PMID:17601530, PMID:18590716 MGI:MGI:3720542, MGI:MGI:3806189 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936
JBrowse link
G MSX2 msh homeobox 2 ISO (MGI:MGI:3806189|PMID:18590716)
(MGI:MGI:3720542|PMID:17601530)
MGI PMID:17601530, PMID:18590716 MGI:MGI:3720542, MGI:MGI:3806189 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896
JBrowse link
G NODAL nodal growth differentiation factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:70,431,936...70,447,951
Ensembl chr10:70,431,936...70,447,951
JBrowse link
G NOG noggin TAS Reactome Reactome:R-HSA-201451 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
G PDCD4 programmed cell death 4 IDA (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a IEA
IBA
(PMID:21873635) Ensembl
GO_Central
InterPro
PMID:21873635 GO_REF:0000002, GO_REF:0000107 NCBI chr15:93,035,271...93,089,211
Ensembl chr15:93,035,273...93,089,204
JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b IEA
IBA
ISS
(PMID:21873635) Ensembl
GO_Central
HGNC
PMID:21873635 GO_REF:0000024, GO_REF:0000107 NCBI chr 5:98,768,632...98,796,494
Ensembl chr 5:98,768,650...98,798,643
JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 9:91,722,598...91,950,228
Ensembl chr 9:91,563,091...91,950,228
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 6:45,328,330...45,551,082
Ensembl chr 6:45,328,157...45,664,349
JBrowse link
G SCX scleraxis bHLH transcription factor ISS UniProtKB GO_REF:0000024 NCBI chr 8:144,265,060...144,268,483
Ensembl chr 8:144,266,453...144,268,481
JBrowse link
G SKI SKI proto-oncogene TAS Reactome Reactome:R-HSA-201451 NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,228,319...2,310,213
JBrowse link
G SLC33A1 solute carrier family 33 member 1 IDA (PMID:25402622) UniProtKB PMID:25402622 NCBI chr 3:155,821,024...155,855,358
Ensembl chr 3:155,821,024...155,854,456
JBrowse link
G SLC39A5 solute carrier family 39 member 5 IMP
IBA
(PMID:24891338)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:24891338 NCBI chr12:56,230,036...56,237,850
Ensembl chr12:56,230,049...56,237,846
JBrowse link
G SMAD1 SMAD family member 1 IMP
IBA
IDA
TAS
ISS
(PMID:19664780)
(PMID:21873635)
(PMID:18548003), (PMID:8653785), (PMID:9389648)
(PMID:19018011)
BHF-UCL
GO_Central
Reactome
UniProtKB
PMID:8653785, PMID:9389648, PMID:18548003, PMID:19018011, PMID:19664780, PMID:21873635 GO_REF:0000024, Reactome:R-HSA-201451 NCBI chr 4:145,481,306...145,559,176
Ensembl chr 4:145,481,194...145,559,176
JBrowse link
G SMAD2 SMAD family member 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD3 SMAD family member 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:67,065,602...67,195,195
Ensembl chr15:67,063,763...67,195,169
JBrowse link
G SMAD4 SMAD family member 4 IDA
IBA
ISS
TAS
(PMID:9389648)
(PMID:21873635)
BHF-UCL
GO_Central
Reactome
PMID:9389648, PMID:21873635 GO_REF:0000024, Reactome:R-HSA-201451 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SMAD5 SMAD family member 5 ISS
IBA
TAS
(PMID:21873635)
(PMID:19018011)
BHF-UCL
GO_Central
Reactome
UniProtKB
PMID:19018011, PMID:21873635 GO_REF:0000024, Reactome:R-HSA-201451 NCBI chr 5:136,132,845...136,182,733
Ensembl chr 5:136,132,845...136,188,747
JBrowse link
G SMAD6 SMAD family member 6 TAS
IBA
IDA
(PMID:21873635)
(PMID:23455153)
Reactome
GO_Central
UniProtKB
PMID:21873635, PMID:23455153 Reactome:R-HSA-201451 NCBI chr15:66,702,110...66,782,849
Ensembl chr15:66,702,236...66,782,849
JBrowse link
G SMAD7 SMAD family member 7 TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-201451 NCBI chr18:48,919,853...48,950,711
Ensembl chr18:48,919,853...48,952,052
JBrowse link
G SMAD9 SMAD family member 9 ISS
IBA
TAS
(PMID:21873635)
(PMID:19018011)
BHF-UCL
GO_Central
Reactome
PMID:19018011, PMID:21873635 GO_REF:0000024, Reactome:R-HSA-201451 NCBI chr13:36,844,831...36,920,721
Ensembl chr13:36,844,831...36,920,765
JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 IEA Ensembl GO_REF:0000107 NCBI chr16:68,358,327...68,448,703
Ensembl chr16:68,358,327...68,448,508
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 TAS
IDA
(PMID:21572392) Reactome
UniProtKB
PMID:21572392 Reactome:R-HSA-201451 NCBI chr 7:99,027,435...99,144,118
Ensembl chr 7:99,027,438...99,144,100
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 TAS Reactome Reactome:R-HSA-201451 NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307
JBrowse link
G SOSTDC1 sclerostin domain containing 1 IEA GOC GO_REF:0000108 NCBI chr 7:16,461,481...16,465,738
Ensembl chr 7:16,461,481...16,530,580
JBrowse link
G TGFB1 transforming growth factor beta 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFB2 transforming growth factor beta 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TGFB3 transforming growth factor beta 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 IDA (PMID:18184661) BHF-UCL PMID:18184661 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TMEM100 transmembrane protein 100 IDA (PMID:22783020) UniProtKB PMID:22783020 NCBI chr17:55,719,627...55,732,081
Ensembl chr17:55,719,627...55,732,121
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 IEA Ensembl GO_REF:0000107 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G UBE2D1 ubiquitin conjugating enzyme E2 D1 TAS Reactome Reactome:R-HSA-201451 NCBI chr10:58,335,006...58,370,748
Ensembl chr10:58,334,979...58,370,751
JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 TAS Reactome Reactome:R-HSA-201451 NCBI chr 4:102,794,383...102,868,895
Ensembl chr 4:102,794,383...102,868,896
JBrowse link
G USP15 ubiquitin specific peptidase 15 IDA (PMID:21947082) UniProtKB PMID:21947082 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked IDA (PMID:19135894) UniProtKB PMID:19135894 NCBI chr  X:41,085,420...41,236,579
Ensembl chr  X:41,085,445...41,236,579
JBrowse link
G USP9Y ubiquitin specific peptidase 9 Y-linked ISS UniProtKB GO_REF:0000024 NCBI chr  Y:12,701,231...12,860,839
Ensembl chr  Y:12,537,650...12,860,839
JBrowse link
G VSIR V-set immunoregulatory receptor ISO (MGI:MGI:5465045|PMID:22751012) MGI PMID:22751012 MGI:MGI:5465045 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
G ZCCHC12 zinc finger CCHC-type containing 12 ISO (MGI:MGI:4357758|PMID:19416967) MGI PMID:19416967 MGI:MGI:4357758 NCBI chr  X:118,823,824...118,826,968
Ensembl chr  X:118,823,824...118,826,968
JBrowse link
G ZFYVE16 zinc finger FYVE-type containing 16 TAS Reactome Reactome:R-HSA-201451 NCBI chr 5:80,407,615...80,483,379
Ensembl chr 5:80,408,013...80,483,379
JBrowse link
G ZNF8 zinc finger protein 8 IEA Ensembl GO_REF:0000107 NCBI chr19:58,278,955...58,302,791
Ensembl chr19:58,278,955...58,302,791
JBrowse link
BMP signaling pathway involved in heart development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,444...157,876,330
Ensembl chr 2:157,736,444...157,876,330
JBrowse link
G BMP4 bone morphogenetic protein 4 ISS BHF-UCL GO_REF:0000024 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A IC BHF-UCL GO_REF:0000111 NCBI chr10:86,755,786...86,927,969
Ensembl chr10:86,756,601...86,932,838
Ensembl chr10:86,756,601...86,932,838
JBrowse link
G MSX1 msh homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896
JBrowse link
G NOG noggin ISS BHF-UCL GO_REF:0000024 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
BMP signaling pathway involved in heart induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 IDA (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
JBrowse link
G BMP4 bone morphogenetic protein 4 IMP (PMID:20702560) BHF-UCL PMID:20702560 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G POU5F1 POU class 5 homeobox 1 IMP (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETV2 ETS variant transcription factor 2 IEA Ensembl GO_REF:0000107 NCBI chr19:35,641,175...35,644,871
Ensembl chr19:35,641,745...35,644,871
JBrowse link
BMP signaling pathway involved in nephric duct formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 IDA (PMID:10021330) UniProtKB PMID:10021330 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
BMP signaling pathway involved in renal system segmentation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISS UniProtKB GO_REF:0000024 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
BMP signaling pathway involved in spinal cord dorsal/ventral patterning term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRD chordin IMP (PMID:11472837) BHF-UCL PMID:11472837 NCBI chr 3:184,380,073...184,390,739
Ensembl chr 3:184,380,073...184,390,736
JBrowse link
BMP signaling pathway involved in ureter morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISS UniProtKB GO_REF:0000024 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
negative regulation of BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 9:130,713,881...130,887,675
Ensembl chr 9:130,713,016...130,887,675
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor IMP (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BMPER BMP binding endothelial regulator TAS (PMID:18787191) BHF-UCL PMID:18787191 NCBI chr 7:33,904,915...34,156,427
Ensembl chr 7:33,904,308...34,156,427
JBrowse link
G CAV1 caveolin 1 IDA (PMID:15657086) BHF-UCL PMID:15657086 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist ISS (PMID:10049596) BHF-UCL PMID:10049596 NCBI chr 9:14,715,082...14,724,308
Ensembl chr 9:14,719,724...14,722,733
JBrowse link
G CHRD chordin IMP (PMID:11472837) BHF-UCL PMID:11472837 NCBI chr 3:184,380,073...184,390,739
Ensembl chr 3:184,380,073...184,390,736
JBrowse link
G CHRDL1 chordin like 1 IEA Ensembl GO_REF:0000107 NCBI chr  X:110,673,856...110,795,817
Ensembl chr  X:110,673,856...110,795,819
JBrowse link
G CHRDL2 chordin like 2 ISO (MGI:MGI:2683044|PMID:14660436) MGI PMID:14660436 MGI:MGI:2683044 NCBI chr11:74,696,429...74,731,426
Ensembl chr11:74,696,429...74,731,426
Ensembl chr11:74,696,429...74,731,426
JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 IMP (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr 2:36,355,778...36,551,135
Ensembl chr 2:36,355,778...36,551,135
JBrowse link
G CTDSPL2 CTD small phosphatase like 2 IEA Ensembl GO_REF:0000107 NCBI chr15:44,427,329...44,529,038
Ensembl chr15:44,427,622...44,529,038
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 ISS BHF-UCL GO_REF:0000024 NCBI chr19:12,969,576...12,974,760
Ensembl chr19:12,965,159...12,974,762
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IEA Ensembl GO_REF:0000107 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G DLX1 distal-less homeobox 1 IMP (PMID:14671321) UniProtKB PMID:14671321 NCBI chr 2:172,085,507...172,089,674
Ensembl chr 2:172,084,740...172,089,677
JBrowse link
G FSTL3 follistatin like 3 IDA (PMID:17878677) UniProtKB PMID:17878677 NCBI chr19:676,392...683,385
Ensembl chr19:676,392...683,392
JBrowse link
G FZD1 frizzled class receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:91,264,433...91,271,326
Ensembl chr 7:91,264,433...91,271,326
JBrowse link
G GDF3 growth differentiation factor 3 IDA (PMID:18823971) UniProtKB PMID:18823971 NCBI chr12:7,689,784...7,695,775
Ensembl chr12:7,689,784...7,695,775
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist IDA
IMP
(PMID:15539560)
(PMID:16816361), (PMID:27036124)
BHF-UCL
UniProtKB
PMID:15539560, PMID:16816361, PMID:27036124 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106
JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist ISO (MGI:MGI:5507937|PMID:23063586) UniProtKB PMID:23063586 MGI:MGI:5507937 NCBI chr 1:240,489,573...240,612,372
Ensembl chr 1:240,489,573...240,612,155
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 IMP (PMID:12874272) UniProtKB PMID:12874272 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
JBrowse link
G HJV hemojuvelin BMP co-receptor IEA Ensembl GO_REF:0000107 NCBI chr 1:146,017,470...146,021,735
Ensembl chr 1:146,017,468...146,036,746
JBrowse link
G HTRA1 HtrA serine peptidase 1 IEA Ensembl GO_REF:0000107 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907
JBrowse link
G HTRA3 HtrA serine peptidase 3 ISS UniProtKB GO_REF:0000024 NCBI chr 4:8,269,712...8,307,098
Ensembl chr 4:8,269,754...8,307,098
JBrowse link
G LEMD2 LEM domain nuclear envelope protein 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:33,771,213...33,794,274
Ensembl chr 6:33,771,202...33,789,130
JBrowse link
G LEMD3 LEM domain containing 3 IDA
IBA
(PMID:15647271)
(PMID:21873635)
UniProtKB
GO_Central
PMID:15647271, PMID:21873635 NCBI chr12:65,169,583...65,248,355
Ensembl chr12:65,169,583...65,248,355
JBrowse link
G LRP2 LDL receptor related protein 2 ISS UniProtKB GO_REF:0000024 NCBI chr 2:169,127,109...169,362,597
Ensembl chr 2:169,127,109...169,362,534
JBrowse link
G MICOS10-NBL1 MICOS10-NBL1 readthrough IDA
IMP
(PMID:23063586)
(PMID:25561725)
UniProtKB PMID:23063586, PMID:25561725 NCBI chr 1:19,596,979...19,658,452
Ensembl chr 1:19,597,067...19,656,927
Ensembl chr 1:19,597,067...19,656,927
JBrowse link
G MIR675 microRNA 675 ISO (MGI:MGI:5566551|PMID:24532688) MGI PMID:24532688 MGI:MGI:5566551 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831
JBrowse link
G NANOG Nanog homeobox ISO (MGI:MGI:3654744|PMID:16801560) MGI PMID:16801560 MGI:MGI:3654744 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
JBrowse link
G NBL1 NBL1, DAN family BMP antagonist IDA
IMP
(PMID:23063586)
(PMID:25561725)
UniProtKB PMID:23063586, PMID:25561725 NCBI chr 1:19,643,229...19,658,452
Ensembl chr 1:19,596,979...19,658,456
JBrowse link
G NOG noggin ISS
IBA
IDA
(PMID:21873635)
(PMID:10780858), (PMID:15539560), (PMID:8752214)
UniProtKB
GO_Central
BHF-UCL
PMID:8752214, PMID:10780858, PMID:15539560, PMID:21873635 GO_REF:0000024 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
G NOTCH1 notch receptor 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma IMP (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A IEA Ensembl GO_REF:0000107 NCBI chr14:60,245,750...60,299,087
Ensembl chr14:60,245,752...60,299,087
JBrowse link
G RBPMS2 RNA binding protein, mRNA processing factor 2 ISS UniProtKB GO_REF:0000024 NCBI chr15:64,739,891...64,775,589
Ensembl chr15:64,739,891...64,775,589
JBrowse link
G SFRP1 secreted frizzled related protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
G SKI SKI proto-oncogene IDA
IBA
IMP
(PMID:14699069)
(PMID:21873635)
(PMID:17054724)
UniProtKB
GO_Central
PMID:14699069, PMID:17054724, PMID:21873635 NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,228,319...2,310,213
JBrowse link
G SKIL SKI like proto-oncogene IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:170,357,678...170,396,849
Ensembl chr 3:170,357,678...170,396,835
JBrowse link
G SKOR1 SKI family transcriptional corepressor 1 IEA
IBA
IDA
(PMID:21873635)
(PMID:17292623)
InterPro
GO_Central
UniProtKB
PMID:17292623, PMID:21873635 GO_REF:0000002 NCBI chr15:67,825,509...67,834,582
Ensembl chr15:67,819,704...67,834,582
JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr18:47,206,169...47,251,660
Ensembl chr18:47,206,322...47,251,603
Ensembl chr18:47,206,322...47,251,603
JBrowse link
G SMAD6 SMAD family member 6 IDA
IMP
(PMID:9436979)
(PMID:22275001)
BHF-UCL PMID:9436979, PMID:22275001 NCBI chr15:66,702,110...66,782,849
Ensembl chr15:66,702,236...66,782,849
JBrowse link
G SMAD7 SMAD family member 7 IDA (PMID:17438144) BHF-UCL PMID:17438144 NCBI chr18:48,919,853...48,950,711
Ensembl chr18:48,919,853...48,952,052
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 IDA
IBA
TAS
(PMID:27214554)
(PMID:21873635)
(PMID:10458166)
BHF-UCL
GO_Central
UniProtKB
PMID:10458166, PMID:21873635, PMID:27214554 NCBI chr 7:99,027,435...99,144,118
Ensembl chr 7:99,027,438...99,144,100
JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307
JBrowse link
G SORL1 sortilin related receptor 1 ISS UniProt GO_REF:0000024 NCBI chr11:121,452,314...121,633,763
Ensembl chr11:121,452,314...121,633,763
JBrowse link
G SOST sclerostin IDA
IBA
(PMID:14633986)
(PMID:21873635)
MGI
GO_Central
PMID:14633986, PMID:21873635 NCBI chr17:43,753,738...43,758,791
Ensembl chr17:43,753,738...43,758,791
JBrowse link
G SOSTDC1 sclerostin domain containing 1 IDA
IBA
(PMID:15020244)
(PMID:21873635)
UniProtKB
GO_Central
PMID:15020244, PMID:21873635 NCBI chr 7:16,461,481...16,465,738
Ensembl chr 7:16,461,481...16,530,580
JBrowse link
G SPART spartin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:36,301,638...36,370,180
Ensembl chr13:36,301,638...36,370,180
JBrowse link
G TCF7L2 transcription factor 7 like 2 ISO (MGI:MGI:3763872|PMID:17919533) MGI PMID:17919533 MGI:MGI:3763872 NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678
JBrowse link
G TMPRSS6 transmembrane serine protease 6 IEA Ensembl GO_REF:0000107 NCBI chr22:37,065,436...37,110,625
Ensembl chr22:37,065,436...37,109,713
JBrowse link
G TOB1 transducer of ERBB2, 1 IEA Ensembl GO_REF:0000107 NCBI chr17:50,862,223...50,867,978
Ensembl chr17:50,862,223...50,867,978
JBrowse link
G TRIM33 tripartite motif containing 33 IDA (PMID:19135894) UniProtKB PMID:19135894 NCBI chr 1:114,392,787...114,511,203
Ensembl chr 1:114,392,790...114,511,203
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 IEA Ensembl GO_REF:0000107 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G VWC2 von Willebrand factor C domain containing 2 ISS
IBA
(PMID:17400546)
(PMID:21873635)
HGNC
GO_Central
PMID:17400546, PMID:21873635 NCBI chr 7:49,773,638...49,923,777
Ensembl chr 7:49,773,638...49,921,950
JBrowse link
G VWC2L von Willebrand factor C domain containing 2 like IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:214,411,054...214,578,976
Ensembl chr 2:214,411,054...214,578,976
JBrowse link
G WNT1 Wnt family member 1 IMP (PMID:16194878) AgBase PMID:16194878 NCBI chr12:48,978,322...48,982,620
Ensembl chr12:48,978,322...48,982,620
JBrowse link
G WNT5A Wnt family member 5A IEA Ensembl GO_REF:0000107 NCBI chr 3:55,465,715...55,505,261
Ensembl chr 3:55,465,715...55,490,539
JBrowse link
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 IDA (PMID:10706139), (PMID:17118062) UniProtKB PMID:10706139, PMID:17118062 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
positive regulation of BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 IDA (PMID:17068149) BHF-UCL PMID:17068149 NCBI chr12:51,906,913...51,923,361
Ensembl chr12:51,906,908...51,923,361
JBrowse link
G BMP4 bone morphogenetic protein 4 ISS UniProtKB GO_REF:0000024 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 IMP (PMID:17992660) UniProtKB PMID:17992660 NCBI chr 2:202,376,310...202,567,751
Ensembl chr 2:202,376,327...202,567,751
JBrowse link
G CCN1 cellular communication network factor 1 IGI (PMID:20675382) BHF-UCL PMID:20675382 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
Ensembl chr 1:85,580,761...85,584,589
JBrowse link
G CDH5 cadherin 5 IMP (PMID:26598555) ARUK-UCL PMID:26598555 NCBI chr16:66,366,657...66,404,784
Ensembl chr16:66,366,622...66,404,784
JBrowse link
G CRB2 crumbs cell polarity complex component 2 ISS UniProtKB GO_REF:0000024 NCBI chr 9:123,354,065...123,380,326
Ensembl chr 9:123,356,170...123,380,324
JBrowse link
G ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 ISS UniProt GO_REF:0000024 NCBI chr 7:86,876,906...87,059,714
Ensembl chr 7:86,876,906...87,059,654
JBrowse link
G ENG endoglin IDA (PMID:17068149) BHF-UCL PMID:17068149 NCBI chr 9:127,815,012...127,854,773
Ensembl chr 9:127,815,013...127,854,658
Ensembl chr 9:127,815,013...127,854,658
JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 IMP (PMID:21572392) UniProtKB PMID:21572392 NCBI chr10:102,419,222...102,423,138
Ensembl chr10:102,419,189...102,423,136
JBrowse link
G FKBP8 FKBP prolyl isomerase 8 IEA Ensembl GO_REF:0000107 NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077
JBrowse link
G FOXD1 forkhead box D1 ISS UniProtKB GO_REF:0000024 NCBI chr 5:73,446,266...73,448,777
Ensembl chr 5:73,444,827...73,448,777
JBrowse link
G GATA4 GATA binding protein 4 IEA Ensembl GO_REF:0000107 NCBI chr 8:11,676,931...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GATA6 GATA binding protein 6 ISO PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G GDF2 growth differentiation factor 2 IEA Ensembl GO_REF:0000107 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588
JBrowse link
G GDF5 growth differentiation factor 5 IDA (PMID:21976273), (PMID:24098149) UniProtKB PMID:21976273, PMID:24098149 NCBI chr20:35,433,347...35,454,749
Ensembl chr20:35,433,347...35,454,746
JBrowse link
G GPC3 glypican 3 IEA Ensembl GO_REF:0000107 NCBI chr  X:133,535,745...133,985,616
Ensembl chr  X:133,535,745...133,985,594
Ensembl chr  X:133,535,745...133,985,594
JBrowse link
G HES1 hes family bHLH transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HES5 hes family bHLH transcription factor 5 ISS UniProtKB GO_REF:0000024 NCBI chr 1:2,528,745...2,530,554
Ensembl chr 1:2,528,745...2,530,263
JBrowse link
G ILK integrin linked kinase IEA Ensembl GO_REF:0000107 NCBI chr11:6,603,748...6,610,873
Ensembl chr11:6,603,708...6,610,874
JBrowse link
G KCP kielin cysteine rich BMP regulator IEA Ensembl GO_REF:0000107 NCBI chr 7:128,870,645...128,910,719
Ensembl chr 7:128,862,451...128,910,719
JBrowse link
G KDR kinase insert domain receptor ISO (MGI:MGI:4830635|PMID:20406889) DFLAT PMID:20406889 MGI:MGI:4830635 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G MSX1 msh homeobox 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936
JBrowse link
G MSX2 msh homeobox 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896
JBrowse link
G NEO1 neogenin 1 IEA InterPro GO_REF:0000002 NCBI chr15:73,051,715...73,305,206
Ensembl chr15:73,051,710...73,305,205
JBrowse link
G NOTCH1 notch receptor 1 ISS UniProtKB GO_REF:0000024 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NOTCH2 notch receptor 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779
JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 ISS UniProtKB GO_REF:0000024 NCBI chr11:72,002,864...72,080,686
Ensembl chr11:72,002,864...72,080,693
JBrowse link
G PELO pelota mRNA surveillance and ribosome rescue factor IEA Ensembl GO_REF:0000107 NCBI chr 5:52,787,916...52,804,044
Ensembl chr 5:52,787,916...52,804,044
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region ISS BHF-UCL GO_REF:0000024 NCBI chr 4:26,163,458...26,435,131
Ensembl chr 4:26,163,455...26,435,131
JBrowse link
G RNF165 ring finger protein 165 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:46,334,018...46,463,145
Ensembl chr18:46,326,809...46,463,140
JBrowse link
G SMAD2 SMAD family member 2 IMP (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr18:47,808,957...47,931,188
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G SMAD4 SMAD family member 4 IMP (PMID:19366699) BHF-UCL PMID:19366699 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,394...51,085,045
JBrowse link
G SOX11 SRY-box transcription factor 11 ISS UniProtKB GO_REF:0000024 NCBI chr 2:5,692,384...5,701,385
Ensembl chr 2:5,692,384...5,701,385
JBrowse link
G SULF1 sulfatase 1 IMP (PMID:20479257) UniProtKB PMID:20479257 NCBI chr 8:69,466,624...69,660,912
Ensembl chr 8:69,466,624...69,660,915
JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 ISO (MGI:MGI:5617089|PMID:25382630) MGI PMID:25382630 MGI:MGI:5617089 NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 IEA Ensembl GO_REF:0000107 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G UBE2O ubiquitin conjugating enzyme E2 O IDA (PMID:23455153) UniProtKB PMID:23455153 NCBI chr17:76,389,456...76,453,234
Ensembl chr17:76,389,456...76,453,152
JBrowse link
G VSIR V-set immunoregulatory receptor ISO (MGI:MGI:5468994|PMID:20042595) MGI PMID:20042595 MGI:MGI:5468994 NCBI chr10:71,747,556...71,773,520
Ensembl chr10:71,747,556...71,773,520
JBrowse link
G ZNF423 zinc finger protein 423 ISS UniProtKB GO_REF:0000024 NCBI chr16:49,487,524...49,857,919
Ensembl chr16:49,487,524...49,857,919
JBrowse link
positive regulation of Wnt signaling pathway by BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 ISS UniProtKB GO_REF:0000024 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246
JBrowse link
regulation of BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FKBP8 FKBP prolyl isomerase 8 ISO (MGI:MGI:3806189|PMID:18590716) MGI PMID:18590716 MGI:MGI:3806189 NCBI chr19:18,531,763...18,543,573
Ensembl chr19:18,531,751...18,544,077
JBrowse link
G FST follistatin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:53,480,338...53,487,134
Ensembl chr 5:53,480,626...53,487,134
JBrowse link
G FSTL1 follistatin like 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:120,392,293...120,450,993
Ensembl chr 3:120,392,293...120,450,993
JBrowse link
G FSTL3 follistatin like 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:676,392...683,385
Ensembl chr19:676,392...683,392
JBrowse link
G HOXA13 homeobox A13 ISO (MGI:MGI:2662001|PMID:12783783) MGI PMID:12783783 MGI:MGI:2662001 NCBI chr 7:27,194,364...27,200,091
Ensembl chr 7:27,193,503...27,200,091
JBrowse link
G ITGA3 integrin subunit alpha 3 IMP (PMID:24621570) UniProtKB PMID:24621570 NCBI chr17:50,056,065...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G NOG noggin ISO (MGI:MGI:3709795|PMID:17359964) MGI PMID:17359964 MGI:MGI:3709795 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611
JBrowse link
G PCSK6 proprotein convertase subtilisin/kexin type 6 TAS (PMID:10467177) BHF-UCL PMID:10467177 NCBI chr15:101,303,933...101,489,707
Ensembl chr15:101,297,142...101,525,202
JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a IEA Ensembl GO_REF:0000107 NCBI chr15:93,035,271...93,089,211
Ensembl chr15:93,035,273...93,089,204
JBrowse link
G SFRP4 secreted frizzled related protein 4 ISS UniProtKB GO_REF:0000024 NCBI chr 7:37,905,932...37,916,817
Ensembl chr 7:37,905,932...38,025,695
JBrowse link
G SFRP5 secreted frizzled related protein 5 IEA InterPro GO_REF:0000002 NCBI chr10:97,766,751...97,771,999
Ensembl chr10:97,766,751...97,771,999
JBrowse link
G TFAP2B transcription factor AP-2 beta ISS UniProtKB GO_REF:0000024 NCBI chr 6:50,817,692...50,847,619
Ensembl chr 6:50,818,723...50,847,619
JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
JBrowse link
G XIAP X-linked inhibitor of apoptosis TAS (PMID:18414036) UniProtKB PMID:18414036 NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,724...123,913,976
Ensembl chr  X:123,859,724...123,913,976
JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:32,718,004...32,745,106
Ensembl chr15:32,718,004...32,745,106
JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:240,489,573...240,612,372
Ensembl chr 1:240,489,573...240,612,155
JBrowse link
G MICOS10-NBL1 MICOS10-NBL1 readthrough IDA
IBA
(PMID:23063586)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:23063586 NCBI chr 1:19,596,979...19,658,452
Ensembl chr 1:19,597,067...19,656,927
Ensembl chr 1:19,597,067...19,656,927
JBrowse link
G NBL1 NBL1, DAN family BMP antagonist IDA
IBA
(PMID:23063586)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:23063586 NCBI chr 1:19,643,229...19,658,452
Ensembl chr 1:19,596,979...19,658,456
JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CER1 cerberus 1, DAN family BMP antagonist IDA
IBA
ISS
(PMID:9660951)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:9660951, PMID:21873635 GO_REF:0000024 NCBI chr 9:14,715,082...14,724,308
Ensembl chr 9:14,719,724...14,722,733
JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:12,969,576...12,974,760
Ensembl chr19:12,965,159...12,974,762
JBrowse link
G FBN1 fibrillin 1 ISS BHF-UCL GO_REF:0000024 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,306...48,645,849
Ensembl chr15:48,408,306...48,645,849
JBrowse link
G MICOS10-NBL1 MICOS10-NBL1 readthrough ISS BHF-UCL GO_REF:0000024 NCBI chr 1:19,596,979...19,658,452
Ensembl chr 1:19,597,067...19,656,927
Ensembl chr 1:19,597,067...19,656,927
JBrowse link
G NBL1 NBL1, DAN family BMP antagonist ISS BHF-UCL GO_REF:0000024 NCBI chr 1:19,643,229...19,658,452
Ensembl chr 1:19,596,979...19,658,456
JBrowse link
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 IDA (PMID:10706139), (PMID:17118062) UniProtKB PMID:10706139, PMID:17118062 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18650
    response to stimulus 10129
      response to endogenous stimulus 2161
        response to BMP 196
          cellular response to BMP stimulus 196
            BMP signaling pathway 180
              BMP signaling pathway involved in Malpighian tubule cell chemotaxis 0
              BMP signaling pathway involved in determination of left/right symmetry + 0
              BMP signaling pathway involved in forebrain neuron fate commitment 0
              BMP signaling pathway involved in growth plate cartilage chondrocyte development 0
              BMP signaling pathway involved in heart development + 6
              BMP signaling pathway involved in heart induction 3
              BMP signaling pathway involved in mesodermal cell fate specification 1
              BMP signaling pathway involved in nephric duct formation 1
              BMP signaling pathway involved in renal system segmentation 1
              BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
              BMP signaling pathway involved in ureter morphogenesis 1
              negative regulation of BMP signaling pathway + 58
              negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 1
              positive regulation of BMP signaling pathway + 39
              positive regulation of Wnt signaling pathway by BMP signaling pathway 1
              regulation of BMP signaling pathway + 105
              regulation of hair cycle by BMP signaling pathway 0
              specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 1
Path 2
Term Annotations click to browse term
  biological_process 18650
    biological regulation 13283
      regulation of biological process 12625
        regulation of cellular process 12020
          signal transduction 6562
            cell surface receptor signaling pathway 3403
              enzyme linked receptor protein signaling pathway 1155
                transmembrane receptor protein serine/threonine kinase signaling pathway 412
                  BMP signaling pathway 180
                    BMP signaling pathway involved in Malpighian tubule cell chemotaxis 0
                    BMP signaling pathway involved in determination of left/right symmetry + 0
                    BMP signaling pathway involved in forebrain neuron fate commitment 0
                    BMP signaling pathway involved in growth plate cartilage chondrocyte development 0
                    BMP signaling pathway involved in heart development + 6
                    BMP signaling pathway involved in heart induction 3
                    BMP signaling pathway involved in mesodermal cell fate specification 1
                    BMP signaling pathway involved in nephric duct formation 1
                    BMP signaling pathway involved in renal system segmentation 1
                    BMP signaling pathway involved in spinal cord dorsal/ventral patterning 1
                    BMP signaling pathway involved in ureter morphogenesis 1
                    negative regulation of BMP signaling pathway + 58
                    negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 1
                    positive regulation of BMP signaling pathway + 39
                    positive regulation of Wnt signaling pathway by BMP signaling pathway 1
                    regulation of BMP signaling pathway + 105
                    regulation of hair cycle by BMP signaling pathway 0
                    specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.