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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:BMP signaling pathway
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Accession:GO:0030509 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: BMP signalling pathway;   bone morphogenetic protein signaling pathway;   bone morphogenetic protein signalling pathway
 narrow_synonym: decapentaplegic receptor signaling pathway;   decapentaplegic receptor signalling pathway;   decapentaplegic signaling pathway;   dpp receptor signaling pathway;   dpp receptor signalling pathway;   dpp signaling pathway
 related_synonym: BMP receptor signaling pathway
 alt_id: GO:0008101


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BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22729085) Ensembl
MGI		 PMID:22729085 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:19366699)
(PMID:17472960)
(MGI:5751611|PMID:26774823)
(PMID:18436533)		 BHF-UCL
MGI
UniProt		 PMID:17472960 PMID:18436533 PMID:19366699 PMID:26774823 MGI:5751611 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:18436533)
(PMID:19903896)		 BHF-UCL PMID:18436533 PMID:19903896 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G ACVRL1 activin A receptor like type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22783020) Ensembl
MGI		 PMID:22783020 GO_REF:0000107 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G AMHR2 anti-Mullerian hormone receptor type 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:1,788,420...1,795,601
Ensembl chr27:1,789,681...1,795,533 		JBrowse link
G ATF2 activating transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:19,032,376...19,103,382
Ensembl chr36:19,010,717...19,103,292 		JBrowse link
G BMP10 bone morphogenetic protein 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16049014) MGI
TreeGrafter
Ensembl		 PMID:16049014 GO_REF:0000107 GO_REF:0000118 NCBI chr10:67,717,047...67,724,778
Ensembl chr10:67,717,980...67,724,739 		JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14623234), (PMID:19208758), (PMID:19852960), (PMID:20065295), (PMID:25100727)
(PMID:15975920)
(PMID:17472960)		 RGD
MGI
TreeGrafter
Ensembl		 PMID:12398941 PMID:14623234 PMID:15975920 PMID:17472960 PMID:19208758 More... GO_REF:0000107 GO_REF:0000118 RGD:631753 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17472960)
(PMID:15975920)
(PMID:14623234), (PMID:17472960)		 MGI
TreeGrafter
Ensembl		 PMID:14623234 PMID:15975920 PMID:17472960 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,089,429...23,202,176
Ensembl chr12:23,089,459...23,202,348 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14623234), (PMID:19852960) Ensembl
MGI
TreeGrafter		 PMID:14623234 PMID:19852960 GO_REF:0000107 GO_REF:0000118 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14623234) Ensembl
MGI
TreeGrafter		 PMID:14623234 GO_REF:0000107 GO_REF:0000118 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in ISO (PMID:20807528) MGI PMID:20807528 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17699604)
(PMID:16049014)
(PMID:16604073)
(PMID:16943278)
(PMID:9268344)		 Ensembl
MGI
TreeGrafter		 PMID:9268344 PMID:16049014 PMID:16604073 PMID:16943278 PMID:17699604 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11376112)
(PMID:16604073)
(PMID:16049014)		 Ensembl
MGI
TreeGrafter		 PMID:11376112 PMID:16049014 PMID:16604073 GO_REF:0000107 GO_REF:0000118 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17472960) Ensembl
MGI
TreeGrafter		 PMID:17472960 GO_REF:0000107 GO_REF:0000118 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G CHRD chordin involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:17,255,770...17,264,776
Ensembl chr34:17,255,562...17,271,713 		JBrowse link
G CHRDL1 chordin like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:83,816,131...83,936,497
Ensembl chr  X:83,817,880...83,936,949 		JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21350216) Ensembl
MGI		 PMID:21350216 GO_REF:0000107 NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625 		JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:12,300,706...12,307,931
Ensembl chr 9:12,300,708...12,307,663 		JBrowse link
G DLX3 distal-less homeobox 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,018,101...26,022,964
Ensembl chr 9:26,017,689...26,022,736 		JBrowse link
G DLX5 distal-less homeobox 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:22,080,351...22,085,188
Ensembl chr14:22,080,699...22,084,867 		JBrowse link
G DSG4 desmoglein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18692037) Ensembl
MGI		 PMID:18692037 GO_REF:0000107 NCBI chr 7:58,101,294...58,135,376 JBrowse link
G ECSIT ECSIT signaling integrator acts_upstream_of_or_within ISO (PMID:14633973) MGI PMID:14633973 NCBI chr20:49,848,848...49,867,075
Ensembl chr20:49,848,912...49,867,066 		JBrowse link
G EGR1 early growth response 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8769660) Ensembl
MGI		 PMID:8769660 GO_REF:0000107 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G ELAC1 elaC ribonuclease Z 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:23,931,360...23,971,516
Ensembl chr 1:23,960,723...23,969,405 		JBrowse link
G ETV2 ETS variant transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18462699) Ensembl
MGI		 PMID:18462699 GO_REF:0000107 NCBI chr 1:116,971,238...116,974,831
Ensembl chr 1:116,971,365...116,985,796 		JBrowse link
G EXT1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21148566), (PMID:22556407), (PMID:23458899), (PMID:28445472)
(PMID:22556407)		 Ensembl
MGI		 PMID:21148566 PMID:22556407 PMID:23458899 PMID:28445472 GO_REF:0000107 NCBI chr13:17,172,497...17,457,084
Ensembl chr13:17,172,705...17,456,469 		JBrowse link
G FAM83B family with sequence similarity 83 member B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:22,256,452...22,341,919
Ensembl chr12:22,257,110...22,338,231 		JBrowse link
G FAM83D family with sequence similarity 83 member D involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:27,302,442...27,323,780
Ensembl chr24:27,302,469...27,323,350 		JBrowse link
G FAM83E family with sequence similarity 83 member E involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:107,694,963...107,705,303
Ensembl chr 1:107,696,416...107,705,310 		JBrowse link
G FAM83F family with sequence similarity 83 member F involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:25,106,663...25,140,989
Ensembl chr10:25,108,003...25,140,989 		JBrowse link
G FAM83G family with sequence similarity 83 member G involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:41,054,805...41,085,156
Ensembl chr 5:41,055,311...41,084,739 		JBrowse link
G FAM83H family with sequence similarity 83 member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:37,324,090...37,332,421
Ensembl chr13:37,325,548...37,336,834 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FST follistatin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15525533) Ensembl
MGI		 PMID:15525533 GO_REF:0000107 NCBI chr 4:61,779,252...61,785,666
Ensembl chr 4:61,779,259...61,783,260 		JBrowse link
G GDF2 growth differentiation factor 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16049014) TreeGrafter
MGI		 PMID:16049014 GO_REF:0000118 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G GDF7 growth differentiation factor 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16049014) Ensembl
MGI
TreeGrafter		 PMID:16049014 GO_REF:0000107 GO_REF:0000118 NCBI chr17:15,627,739...15,636,513 JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G HIVEP1 HIVEP zinc finger 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:11,551,270...11,705,629
Ensembl chr35:11,555,221...11,705,002 		JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16604073)
(PMID:19751239)
(PMID:16604073), (PMID:24409331)		 Ensembl
MGI
TreeGrafter		 PMID:16604073 PMID:19751239 PMID:24409331 GO_REF:0000107 GO_REF:0000118 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G ID1 inhibitor of DNA binding 1 acts_upstream_of_or_within ISO (PMID:15820682) MGI PMID:15820682 NCBI chr24:21,094,339...21,096,276
Ensembl chr24:21,094,755...21,096,276 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9769173) Ensembl
MGI		 PMID:9769173 GO_REF:0000107 NCBI chr32:28,516,002...28,633,759
Ensembl chr32:28,517,108...28,634,019 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:19664780) BHF-UCL PMID:19664780 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MEGF8 multiple EGF like domains 8 involved_in ISO (MGI:5551355|PMID:24052814) UniProt PMID:24052814 MGI:5551355 NCBI chr 1:112,020,344...112,063,120
Ensembl chr 1:112,021,960...112,024,773 		JBrowse link
G MIR122 microRNA mir-122 acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr 1:17,593,858...17,593,915
Ensembl chr 1:17,593,837...17,593,929 		JBrowse link
G MIR125A microRNA mir-125a acts_upstream_of_or_within ISO (PMID:22751012) MGI PMID:22751012 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
G MIR147 microRNA mir-147 acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr30:11,800,621...11,800,706
Ensembl chr30:11,800,621...11,800,706 		JBrowse link
G MIR16-1 microRNA mir-16-1 acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr22:1,847,020...1,847,084
Ensembl chr22:1,847,007...1,847,093 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:18548003) BHF-UCL PMID:18548003 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR23A microRNA mir-23a acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr20:48,620,335...48,620,386
Ensembl chr20:48,620,323...48,620,397 		JBrowse link
G MIRLET7D microRNA let-7d acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr 1:97,902,012...97,902,136
Ensembl chr 1:97,902,012...97,902,136 		JBrowse link
G MIRLET7F microRNA let-7f acts_upstream_of_or_within ISO (PMID:19520079) MGI PMID:19520079 NCBI chr 1:97,903,931...97,904,008
Ensembl chr 1:97,903,919...97,904,028 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17601530), (PMID:18667074)
(PMID:18590716)
(PMID:18667074)		 Ensembl
MGI		 PMID:17601530 PMID:18590716 PMID:18667074 GO_REF:0000107 NCBI chr 3:70,232,790...70,236,295
Ensembl chr 3:70,232,052...70,236,447 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:18590716)
(PMID:18667074)
(PMID:17601530), (PMID:18667074)		 MGI PMID:17601530 PMID:18590716 PMID:18667074 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of ISO (PMID:16801560) MGI PMID:16801560 NCBI chr27:37,262,558...37,266,449 JBrowse link
G NFIA nuclear factor I A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:48,489,521...49,064,867
Ensembl chr 5:48,496,773...49,064,848 		JBrowse link
G NOG noggin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18462699) Ensembl
MGI		 PMID:18462699 GO_REF:0000107 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:23676271) Ensembl
MGI		 PMID:23676271 GO_REF:0000107 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857 		JBrowse link
G PDCD4 programmed cell death 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:22,198,274...22,227,184
Ensembl chr28:22,198,322...22,226,717 		JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:18382765) BHF-UCL PMID:18382765 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15975920) Ensembl
MGI
TreeGrafter		 PMID:15975920 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b acts_upstream_of_or_within ISO (PMID:15671031) MGI PMID:15671031 NCBI chr 3:11,407,426...11,427,317 JBrowse link
G RGMB repulsive guidance molecule BMP co-receptor b involved_in IEA TreeGrafter GO_REF:0000118
G ROR2 receptor tyrosine kinase like orphan receptor 2 acts_upstream_of_or_within ISO (PMID:20660756) MGI PMID:20660756 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G SCX scleraxis bHLH transcription factor involved_in ISO (MGI:4418577|PMID:20059955) UniProt PMID:20059955 MGI:4418577 NCBI chr13:37,701,781...37,704,949
Ensembl chr13:37,703,232...37,704,657 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of ISO (PMID:19850029) MGI PMID:19850029 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SLC39A5 solute carrier family 39 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:552,755...557,319 JBrowse link
G SMAD1 SMAD family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15198985)
(PMID:19224984)
(PMID:16604073)
(PMID:25100727)		 RGD
MGI
TreeGrafter
Ensembl		 PMID:15198985 PMID:16020542 PMID:16604073 PMID:19224984 PMID:25100727 GO_REF:0000107 GO_REF:0000118 RGD:1643232 NCBI chr15:44,093,491...44,171,177
Ensembl chr15:44,095,497...44,170,098 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SMAD5 SMAD family member 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19224984)
(PMID:18590716)		 Ensembl
MGI
TreeGrafter		 PMID:18590716 PMID:19224984 GO_REF:0000107 GO_REF:0000118 NCBI chr11:24,027,603...24,082,673
Ensembl chr11:24,028,126...24,078,169 		JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD9 SMAD family member 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716)
(PMID:19224984)		 TreeGrafter
MGI		 PMID:18590716 PMID:19224984 GO_REF:0000118 NCBI chr25:3,768,851...3,844,645
Ensembl chr25:3,779,197...3,841,321 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24505141) Ensembl
MGI		 PMID:24505141 GO_REF:0000107 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SOST sclerostin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17002572) Ensembl
MGI		 PMID:17002572 GO_REF:0000107 NCBI chr 9:19,538,713...19,544,650
Ensembl chr 9:19,539,435...19,544,651 		JBrowse link
G SOSTDC1 sclerostin domain containing 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16179481) Ensembl
MGI		 PMID:16179481 GO_REF:0000107 NCBI chr14:31,035,759...31,079,139
Ensembl chr14:31,022,766...31,026,737
Ensembl chr14:31,022,766...31,026,737 		JBrowse link
G SPART spartin involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22619377) Ensembl
MGI		 PMID:22619377 GO_REF:0000107 NCBI chr25:4,256,177...4,302,854
Ensembl chr25:4,232,533...4,316,363 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of ISO (PMID:17919533) MGI PMID:17919533 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:25382630) Ensembl
MGI		 PMID:25382630 GO_REF:0000107 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TMEM100 transmembrane protein 100 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:30,695,711...30,701,730
Ensembl chr 9:30,696,765...30,697,169 		JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19751239) Ensembl
MGI		 PMID:19751239 GO_REF:0000107 NCBI chr10:27,393,650...27,435,893
Ensembl chr10:27,397,123...27,435,908 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14681194) Ensembl
MGI		 PMID:14681194 GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G USP15 ubiquitin specific peptidase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,510,759...5,634,954
Ensembl chr10:5,510,022...5,634,202 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in ISO (PMID:19135894) UniProt PMID:19135894 NCBI chr  X:35,522,873...35,676,086 JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of
acts_upstream_of_or_within		 ISO (PMID:20042595)
(PMID:22751012)		 MGI PMID:20042595 PMID:22751012 NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
G ZCCHC12 zinc finger CCHC-type containing 12 acts_upstream_of_or_within ISO (PMID:19416967) MGI PMID:19416967 NCBI chr  X:91,004,777...91,008,019 JBrowse link
G ZNF8 zinc finger protein 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12370310) Ensembl
MGI		 PMID:12370310 GO_REF:0000107 NCBI chr 1:99,644,778...99,654,993
Ensembl chr 1:99,642,446...99,655,014 		JBrowse link
negative regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22729085) Ensembl
MGI		 PMID:22729085 GO_REF:0000107 NCBI chr 9:53,118,462...53,262,092
Ensembl chr 9:53,119,641...53,261,307 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21743293) ARUK-UCL
Ensembl		 PMID:21743293 GO_REF:0000107 NCBI chr 2:17,453,628...17,459,812
Ensembl chr 2:17,455,243...17,462,346 		JBrowse link
G BMPER BMP binding endothelial regulator acts_upstream_of_or_within ISO (PMID:12897139) MGI PMID:12897139 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G CAV1 caveolin 1 involved_in ISO (PMID:15657086) BHF-UCL PMID:15657086 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9431803), (PMID:9501024) Ensembl
MGI		 PMID:9431803 PMID:9501024 GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G CHRD chordin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15780974), (PMID:19850029) Ensembl
TreeGrafter
MGI		 PMID:15780974 PMID:19850029 GO_REF:0000107 GO_REF:0000118 NCBI chr34:17,255,770...17,264,776
Ensembl chr34:17,255,562...17,271,713 		JBrowse link
G CHRDL1 chordin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23676271) Ensembl
MGI
TreeGrafter		 PMID:23676271 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:83,816,131...83,936,497
Ensembl chr  X:83,817,880...83,936,949 		JBrowse link
G CHRDL2 chordin like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14660436) TreeGrafter
MGI		 PMID:14660436 GO_REF:0000118 NCBI chr21:23,670,257...23,702,788
Ensembl chr21:23,670,238...23,702,788 		JBrowse link
G CRIM1 cysteine rich transmembrane BMP regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21743293) ARUK-UCL
Ensembl		 PMID:21743293 GO_REF:0000107 NCBI chr17:28,857,702...29,042,399
Ensembl chr17:28,857,696...29,040,002 		JBrowse link
G CTDSPL2 CTD small phosphatase like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25100727) Ensembl
MGI		 PMID:25100727 GO_REF:0000107 NCBI chr30:11,109,571...11,194,985
Ensembl chr30:11,109,664...11,193,534 		JBrowse link
G DAND5 DAN domain BMP antagonist family member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:49,225,351...49,228,940
Ensembl chr20:49,225,990...49,228,940 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 acts_upstream_of_or_within ISO (PMID:19850029) MGI PMID:19850029 NCBI chr26:35,697,428...35,701,596
Ensembl chr26:35,697,618...35,701,496 		JBrowse link
G DLX1 distal-less homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:16,485,158...16,489,397
Ensembl chr36:16,484,859...16,487,886 		JBrowse link
G FSTL3 follistatin like 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11010968) Ensembl
MGI		 PMID:11010968 GO_REF:0000107 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
G FZD1 frizzled class receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14627707) Ensembl
MGI		 PMID:14627707 GO_REF:0000107 NCBI chr14:17,046,911...17,050,515
Ensembl chr14:17,047,382...17,049,337 		JBrowse link
G GDF3 growth differentiation factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:37,125,845...37,129,567
Ensembl chr27:37,125,928...37,129,484 		JBrowse link
G GPR155 G protein-coupled receptor 155 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr36:18,481,269...18,524,733
Ensembl chr36:18,482,910...18,520,192 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17522159) Ensembl
MGI		 PMID:17522159 GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:32,048,151...32,157,698
Ensembl chr 7:32,048,183...32,157,146 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,066,957...9,256,916
Ensembl chr16:9,066,970...9,244,526 		JBrowse link
G HJV hemojuvelin BMP co-receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20065295) Ensembl
MGI		 PMID:20065295 GO_REF:0000107 NCBI chr17:58,792,647...58,797,504
Ensembl chr17:58,793,247...58,797,373 		JBrowse link
G HTRA1 HtrA serine peptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14973287) Ensembl
MGI		 PMID:14973287 GO_REF:0000107 NCBI chr28:32,133,779...32,157,835
Ensembl chr28:32,132,547...32,157,409 		JBrowse link
G HTRA3 HtrA serine peptidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:60,081,087...60,111,847
Ensembl chr 3:60,081,087...60,111,170 		JBrowse link
G LEMD2 LEM domain nuclear envelope protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:3,114,175...3,131,779
Ensembl chr12:3,115,460...3,131,919 		JBrowse link
G LEMD3 LEM domain containing 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:7,775,995...7,833,895
Ensembl chr10:7,777,946...7,834,107 		JBrowse link
G LRP2 LDL receptor related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:13,910,450...14,107,081
Ensembl chr36:13,911,865...14,107,546 		JBrowse link
G MIR125B-1 microRNA mir-125b-1 acts_upstream_of ISO (PMID:28214897) BHF-UCL PMID:28214897 NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745 		JBrowse link
G MIR125B-2 microRNA mir-125b-2 acts_upstream_of ISO (PMID:28214897) BHF-UCL PMID:28214897 NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052 		JBrowse link
G MIR195 microRNA mir-195 involved_in ISO (PMID:31921616) BHF-UCL PMID:31921616 NCBI chr 5:32,045,450...32,045,510
Ensembl chr 5:32,045,450...32,045,510 		JBrowse link
G MIR199-1 microRNA mir-199-1 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr20:50,410,924...50,410,984
Ensembl chr20:50,410,913...50,410,994 		JBrowse link
G MIR199-2 microRNA mir-199-2 involved_in ISO (PMID:22821565) BHF-UCL PMID:22821565 NCBI chr 7:26,812,766...26,812,824
Ensembl chr 7:26,812,735...26,812,838 		JBrowse link
G MIR199-3 microRNA mir-199-3 involved_in ISO (PMID:32082362) BHF-UCL PMID:32082362 NCBI chr 9:55,262,354...55,262,412
Ensembl chr 9:55,262,328...55,262,437 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:22450430) BHF-UCL PMID:22450430 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR214 microRNA mir-214 acts_upstream_of ISO (PMID:30703347) BHF-UCL PMID:30703347 NCBI chr 7:26,818,559...26,818,668
Ensembl chr 7:26,818,559...26,818,670 		JBrowse link
G MIR26A-1 microRNA mir-26a-1 involved_in ISO (PMID:24047927) BHF-UCL PMID:24047927 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140 		JBrowse link
G MIR26A-2 microRNA mir-26a-2 involved_in ISO (PMID:24047927) BHF-UCL PMID:24047927 NCBI chr10:1,880,513...1,880,572
Ensembl chr10:1,880,513...1,880,572 		JBrowse link
G MIR302C microRNA mir-302c acts_upstream_of ISO (PMID:22988237) BHF-UCL PMID:22988237 NCBI chr32:32,429,366...32,429,433
Ensembl chr32:32,429,366...32,429,433 		JBrowse link
G MIR885 microRNA mir-885 acts_upstream_of ISO (PMID:24882581) BHF-UCL PMID:24882581 NCBI chr20:7,968,529...7,968,602
Ensembl chr20:7,968,529...7,968,602 		JBrowse link
G MIR93 microRNA mir-93 acts_upstream_of ISO (PMID:28797104) BHF-UCL PMID:28797104 NCBI chr 6:9,498,780...9,498,840 JBrowse link
G MIR98 microRNA mir-98 acts_upstream_of ISO (PMID:27860183) BHF-UCL PMID:27860183 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775 		JBrowse link
G MIR99A-2 microRNA mir-99a-2 acts_upstream_of ISO (PMID:22684006) BHF-UCL PMID:22684006 NCBI chr 5:12,047,369...12,047,425
Ensembl chr 5:12,047,369...12,047,425 		JBrowse link
G MTMR4 myotubularin related protein 4 involved_in ISO (PMID:23150675) FlyBase PMID:23150675 NCBI chr 9:33,110,983...33,136,843
Ensembl chr 9:33,112,143...33,136,684 		JBrowse link
G NANOG Nanog homeobox acts_upstream_of_or_within ISO (PMID:16801560) MGI PMID:16801560 NCBI chr27:37,262,558...37,266,449 JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23676271) Ensembl
MGI		 PMID:23676271 GO_REF:0000107 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16712836)
(PMID:19852960)
(PMID:15110716), (PMID:15975920), (PMID:18462699), (PMID:19850029)		 UniProt
MGI
TreeGrafter
Ensembl
InterPro		 PMID:15110716 PMID:15975920 PMID:16712836 PMID:18462699 PMID:19850029 More... GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25100727) Ensembl
MGI		 PMID:25100727 GO_REF:0000107 NCBI chr 8:35,336,055...35,384,249
Ensembl chr 8:35,336,140...35,377,551 		JBrowse link
G PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr34:17,180,119...17,189,298
Ensembl chr34:17,180,098...17,189,303 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:19850029) MGI PMID:19850029 NCBI chr15:51,541,197...51,548,765
Ensembl chr15:51,540,500...51,548,765 		JBrowse link
G SKI SKI proto-oncogene involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21937600) Ensembl
MGI
TreeGrafter		 PMID:21937600 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:57,144,178...57,216,385
Ensembl chr 5:57,145,825...57,214,403 		JBrowse link
G SKIL SKI like proto-oncogene involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr34:34,871,770...34,898,681
Ensembl chr34:34,871,574...34,894,854 		JBrowse link
G SKOR1 SKI family transcriptional corepressor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr30:31,935,860...31,948,161
Ensembl chr30:31,938,869...31,948,218 		JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21937600) TreeGrafter
MGI		 PMID:21937600 GO_REF:0000118 NCBI chr 7:44,250,822...44,289,737 JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:30,938,908...31,014,259
Ensembl chr30:30,937,849...31,014,583 		JBrowse link
G SMAD7 SMAD family member 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19850029) Ensembl
MGI		 PMID:19850029 GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:10,385,781...10,498,071
Ensembl chr 6:10,385,779...10,494,922 		JBrowse link
G SMURF2 SMAD specific E3 ubiquitin protein ligase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:12,348,777...12,472,636
Ensembl chr 9:12,351,627...12,471,467 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784 		JBrowse link
G SOST sclerostin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:14633986)
(PMID:17002572)		 MGI
TreeGrafter
Ensembl		 PMID:14633986 PMID:17002572 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:19,538,713...19,544,650
Ensembl chr 9:19,539,435...19,544,651 		JBrowse link
G SOSTDC1 sclerostin domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14623234), (PMID:16179481)
(PMID:16179481)		 Ensembl
MGI
TreeGrafter		 PMID:14623234 PMID:16179481 GO_REF:0000107 GO_REF:0000118 NCBI chr14:31,035,759...31,079,139
Ensembl chr14:31,022,766...31,026,737
Ensembl chr14:31,022,766...31,026,737 		JBrowse link
G SPART spartin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22619377) Ensembl
MGI
TreeGrafter		 PMID:22619377 GO_REF:0000107 GO_REF:0000118 NCBI chr25:4,256,177...4,302,854
Ensembl chr25:4,232,533...4,316,363 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:17919533) MGI PMID:17919533 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737 		JBrowse link
G TMEM53 transmembrane protein 53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:15,640,232...15,661,829
Ensembl chr15:15,640,342...15,678,994 		JBrowse link
G TMPRSS6 transmembrane serine protease 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19751239) Ensembl
MGI		 PMID:19751239 GO_REF:0000107 NCBI chr10:27,393,650...27,435,893
Ensembl chr10:27,397,123...27,435,908 		JBrowse link
G TNFAIP6 TNF alpha induced protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,607,598...52,623,799
Ensembl chr19:52,607,713...52,623,811 		JBrowse link
G TOB1 transducer of ERBB2, 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11163184) Ensembl
MGI		 PMID:11163184 GO_REF:0000107 NCBI chr 9:26,736,805...26,741,119
Ensembl chr 9:26,736,675...26,740,177
Ensembl chr 9:26,736,675...26,740,177 		JBrowse link
G TRIM33 tripartite motif containing 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,117,085...52,230,846
Ensembl chr17:52,118,476...52,230,530 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12665593)
(PMID:15780974)		 Ensembl
MGI		 PMID:12665593 PMID:15780974 GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G VWC2 von Willebrand factor C domain containing 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:1,248,612...1,350,965
Ensembl chr18:1,257,357...1,350,856 		JBrowse link
G VWC2L von Willebrand factor C domain containing 2 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19852960) Ensembl
MGI
TreeGrafter		 PMID:19852960 GO_REF:0000107 GO_REF:0000118 NCBI chr37:21,690,649...21,845,435
Ensembl chr37:21,694,137...21,842,599 		JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:5,588,151...5,592,254
Ensembl chr27:5,574,940...5,592,060 		JBrowse link
G WNT5A Wnt family member 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
positive regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:3,075,373...3,090,549
Ensembl chr27:3,076,124...3,092,469 		JBrowse link
G ARK2C arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23610558) Ensembl
MGI
TreeGrafter		 PMID:23610558 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:44,834,006...44,939,538
Ensembl chr 7:44,840,099...44,940,619 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMPER BMP binding endothelial regulator involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:45,910,634...46,154,922
Ensembl chr14:45,910,739...46,153,501 		JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994 		JBrowse link
G CDH5 cadherin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:82,830,505...82,863,931
Ensembl chr 5:82,830,939...82,863,882 		JBrowse link
G CRB2 crumbs cell polarity complex component 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:59,427,661...59,450,436
Ensembl chr 9:59,427,569...59,450,434 		JBrowse link
G ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:13,074,575...13,245,312
Ensembl chr14:13,076,932...13,245,319 		JBrowse link
G ENG endoglin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 involved_in ISS UniProt GO_REF:0000024 NCBI chr28:14,927,740...14,929,867
Ensembl chr28:14,927,532...14,929,863 		JBrowse link
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FOXD1 forkhead box D1 involved_in ISO (MGI:3525902|PMID:15634693) UniProt PMID:15634693 MGI:3525902
G GATA4 GATA binding protein 4 involved_in ISO PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr25:26,126,172...26,211,474
Ensembl chr25:26,127,853...26,182,989 		JBrowse link
G GATA6 GATA binding protein 6 involved_in ISO PMID:12606287 BHF-UCL PMID:12606287 RGD:8554170 NCBI chr 7:65,932,114...65,962,574 JBrowse link
G GDF2 growth differentiation factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,996,767...35,001,094
Ensembl chr 4:34,997,579...35,001,203 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GPC3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15925496) Ensembl
MGI		 PMID:15925496 GO_REF:0000107 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107
G HES5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18579678) Ensembl
MGI		 PMID:18579678 GO_REF:0000107 NCBI chr 5:57,387,961...57,389,412
Ensembl chr 5:57,388,674...57,389,388 		JBrowse link
G ILK integrin linked kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,911,326...29,917,972
Ensembl chr21:29,911,364...29,917,974 		JBrowse link
G KCP kielin cysteine rich BMP regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15793581) Ensembl
MGI
TreeGrafter		 PMID:15793581 GO_REF:0000107 GO_REF:0000118 NCBI chr14:7,752,162...7,776,428
Ensembl chr14:7,751,351...7,780,558 		JBrowse link
G KDR kinase insert domain receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G MIR140 microRNA mir-140 involved_in ISO (PMID:27214554) BHF-UCL PMID:27214554 NCBI chr 5:79,814,256...79,814,316
Ensembl chr 5:79,814,246...79,814,326 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:21743293) ARUK-UCL PMID:21743293 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MSX1 msh homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18667074) Ensembl
MGI		 PMID:18667074 GO_REF:0000107 NCBI chr 3:70,232,790...70,236,295
Ensembl chr 3:70,232,052...70,236,447 		JBrowse link
G MSX2 msh homeobox 2 acts_upstream_of_or_within ISO (PMID:18667074) MGI PMID:18667074 NCBI chr 4:38,002,724...38,007,407
Ensembl chr 4:38,002,428...38,007,407 		JBrowse link
G NEO1 neogenin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20065295) Ensembl
MGI		 PMID:20065295 GO_REF:0000107 NCBI chr30:36,387,425...36,622,491
Ensembl chr30:36,387,259...36,622,154 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G NOTCH2 notch receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23676271) Ensembl
MGI		 PMID:23676271 GO_REF:0000107 NCBI chr17:56,854,825...57,020,157
Ensembl chr17:56,860,429...57,020,857 		JBrowse link
G NUMA1 nuclear mitotic apparatus protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:26,000,579...26,076,281
Ensembl chr21:26,037,095...26,075,549 		JBrowse link
G PELO pelota mRNA surveillance and ribosome rescue factor acts_upstream_of_or_within ISO (PMID:24835669) MGI PMID:24835669 NCBI chr 4:62,440,923...62,443,598 JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360 		JBrowse link
G SCUBE3 signal peptide, CUB domain and EGF like domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,383,649...4,420,844
Ensembl chr12:4,382,916...4,418,300 		JBrowse link
G SMAD2 SMAD family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,696,883...43,778,063
Ensembl chr 7:43,700,445...43,769,983 		JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in IEA Ensembl GO_REF:0000107
G SULF1 sulfatase 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr29:18,709,406...18,885,248
Ensembl chr29:18,709,445...18,884,378 		JBrowse link
G TBX20 T-box transcription factor 20 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:5299248|PMID:21983003) BHF-UCL
Ensembl		 PMID:21983003 GO_REF:0000107 MGI:5299248 NCBI chr14:46,891,706...46,946,899
Ensembl chr14:46,896,228...46,947,507 		JBrowse link
G TGFBR3 transforming growth factor beta receptor 3 acts_upstream_of_or_within ISO (PMID:25382630) MGI PMID:25382630 NCBI chr 6:57,025,096...57,220,240
Ensembl chr 6:57,025,112...57,217,121 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12665593) Ensembl
MGI		 PMID:12665593 GO_REF:0000107 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
G UBE2O ubiquitin conjugating enzyme E2 O involved_in ISO (PMID:23455153) UniProt PMID:23455153 NCBI chr 9:4,294,192...4,310,971
Ensembl chr 9:4,254,649...4,310,589 		JBrowse link
G VSIR V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:20042595) MGI PMID:20042595 NCBI chr 4:22,504,888...22,530,702
Ensembl chr 4:22,459,363...22,530,687 		JBrowse link
G ZNF423 zinc finger protein 423 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,512,342...65,778,410
Ensembl chr 2:65,438,842...65,778,407 		JBrowse link
regulation of BMP signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FKBP8 FKBP prolyl isomerase 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18590716) Ensembl
MGI		 PMID:18590716 GO_REF:0000107 NCBI chr20:44,494,856...44,504,084
Ensembl chr20:44,489,219...44,598,497 		JBrowse link
G FSTL1 follistatin like 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr33:23,892,317...23,914,406
Ensembl chr33:23,894,573...23,933,779 		JBrowse link
G FSTL3 follistatin like 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
G FSTL4 follistatin like 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:21,453,982...21,850,969
Ensembl chr11:21,458,678...21,856,547 		JBrowse link
G FSTL5 follistatin like 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:57,985,075...58,621,937
Ensembl chr15:57,986,912...58,670,930 		JBrowse link
G HOXA13 homeobox A13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12783783) Ensembl
MGI		 PMID:12783783 GO_REF:0000107 NCBI chr14:40,371,234...40,375,261
Ensembl chr14:40,373,059...40,375,980 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422 		JBrowse link
G NOG noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17359964) Ensembl
MGI		 PMID:17359964 GO_REF:0000107 NCBI chr 9:31,453,604...31,456,060 JBrowse link
G PRMT1 protein arginine methyltransferase 1 involved_in ISO (PMID:33667543) UniProt PMID:33667543 NCBI chr 1:106,849,864...106,859,896
Ensembl chr 1:106,849,864...106,874,075 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17472960) Ensembl
MGI		 PMID:17472960 GO_REF:0000107 NCBI chr 3:47,044,342...47,089,923
Ensembl chr 3:47,061,910...47,089,294 		JBrowse link
G SFRP4 secreted frizzled related protein 4 involved_in ISO (MGI:5790095|PMID:27355534) UniProt PMID:27355534 MGI:5790095 NCBI chr18:12,018,049...12,028,123
Ensembl chr18:12,017,978...12,027,788 		JBrowse link
G TFAP2B transcription factor AP-2 beta involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:18,544,176...18,574,300
Ensembl chr12:18,544,446...18,572,902 		JBrowse link
G TWSG1 twisted gastrulation BMP signaling modulator 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:75,337,347...75,397,485
Ensembl chr 7:75,335,235...75,398,325 		JBrowse link
sequestering of BMP from receptor via BMP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:32,048,151...32,157,698
Ensembl chr 7:32,048,183...32,157,146 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
sequestering of BMP in extracellular matrix term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G FBN1 fibrillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:14,640,973...14,864,151
Ensembl chr30:14,640,973...14,864,151 		JBrowse link
G NBL1 NBL1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:79,040,206...79,102,792
Ensembl chr 2:79,041,105...79,102,820 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    response to stimulus 9451
      response to endogenous stimulus 2186
        cellular response to endogenous stimulus 1759
          cellular response to growth factor stimulus 888
            cellular response to BMP stimulus 205
              BMP signaling pathway 187
                negative regulation of BMP signaling pathway + 75
                positive regulation of BMP signaling pathway 42
                regulation of BMP signaling pathway + 122
Path 2
Term Annotations click to browse term
  biological_process 17917
    biological regulation 12438
      regulation of biological process 12078
        regulation of cellular process 11571
          signal transduction 6326
            cell surface receptor signaling pathway 2805
              enzyme-linked receptor protein signaling pathway 1041
                cell surface receptor protein serine/threonine kinase signaling pathway 435
                  transforming growth factor beta receptor superfamily signaling pathway 405
                    BMP signaling pathway 187
                      negative regulation of BMP signaling pathway + 75
                      positive regulation of BMP signaling pathway 42
                      regulation of BMP signaling pathway + 122
paths to the root