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ONTOLOGY REPORT - ANNOTATIONS

Term:spectrin binding
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Accession:GO:0030507 term browser browse the term
Definition:Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.


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spectrin binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 enables ISO (PMID:7642559) BHF-UCL PMID:7642559 NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,062...1,710,650 		JBrowse link
G ADD2 adducin 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:71,729,882...71,845,761
Ensembl chr 3:71,730,003...71,840,861 		JBrowse link
G ANK1 ankyrin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:10,752,258...10,985,129
Ensembl chr17:10,779,055...10,985,191 		JBrowse link
G ANK2 ankyrin 2 enables ISO (PMID:15262991) BHF-UCL PMID:15262991 NCBI chr 8:109,306,793...109,661,970 JBrowse link
G ANK3 ankyrin 3 enables ISO PMID:17620337 BHF-UCL PMID:17620337 RGD:8693373 NCBI chr14:63,416,154...63,809,220 JBrowse link
G CAMSAP1 calmodulin regulated spectrin associated protein 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107
G CAMSAP2 calmodulin regulated spectrin associated protein family member 2 enables IEA InterPro GO_REF:0000002 NCBI chr10:23,275,302...23,360,167
Ensembl chr10:23,275,322...23,360,167 		JBrowse link
G CAMSAP3 calmodulin regulated spectrin associated protein family member 3 enables IEA InterPro GO_REF:0000002 NCBI chr 2:71,531,607...71,547,413
Ensembl chr 2:71,531,614...71,547,419 		JBrowse link
G DCTN2 dynactin subunit 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 5:22,799,286...22,814,358
Ensembl chr 5:22,799,287...22,814,362 		JBrowse link
G DMTN dematin actin binding protein enables IEA Ensembl GO_REF:0000107 NCBI chr14:6,315,643...6,346,722
Ensembl chr14:6,321,870...6,346,865 		JBrowse link
G DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:75,414,663...75,760,527
Ensembl chr 9:75,414,755...75,760,519 		JBrowse link
G EPB41 erythrocyte membrane protein band 4.1 enables ISO PMID:23704327 MGI PMID:23704327 RGD:8553853 NCBI chr 6:85,842,538...86,029,522
Ensembl chr 6:85,865,277...86,029,508 		JBrowse link
G EPB41L2 erythrocyte membrane protein band 4.1 like 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:32,418,210...32,630,643
Ensembl chr 1:32,418,217...32,630,638 		JBrowse link
G GBP1 guanylate binding protein 1, interferon-inducible enables IEA Ensembl GO_REF:0000107 NCBI chr 4:127,425,699...127,442,132
Ensembl chr 4:127,425,200...127,442,127 		JBrowse link
G GNB1 G protein subunit beta 1 enables ISO PMID:23704327 MGI PMID:23704327 RGD:8553853 NCBI chr 6:63,867,155...63,957,514
Ensembl chr 6:63,867,158...63,952,505 		JBrowse link
G GNB3 G protein subunit beta 3 enables ISO PMID:23704327 MGI PMID:23704327 RGD:8553853 NCBI chr 5:63,863,656...63,871,352
Ensembl chr 5:63,863,661...63,870,433 		JBrowse link
G KIF3A kinesin family member 3A enables ISO (PMID:23704327) MGI PMID:23704327 NCBI chr 2:134,932,339...135,069,408
Ensembl chr 2:134,932,615...135,069,377 		JBrowse link
G MYO10 myosin X enables IEA Ensembl GO_REF:0000107 NCBI chr16:5,907,111...6,145,485
Ensembl chr16:5,907,116...6,094,845 		JBrowse link
G MYO7A myosin VIIA enables IEA Ensembl GO_REF:0000107 NCBI chr 9:11,251,187...11,337,618
Ensembl chr 9:11,249,075...11,666,296 		JBrowse link
G PDE6G phosphodiesterase 6G enables ISO PMID:23704327 MGI PMID:23704327 RGD:8553853 NCBI chr12:1,235,886...1,239,808
Ensembl chr12:1,236,210...1,239,306 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C enables IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G PTPRN protein tyrosine phosphatase receptor type N enables IEA Ensembl GO_REF:0000107 NCBI chr15:121,329,284...121,349,228
Ensembl chr15:121,329,287...121,349,168 		JBrowse link
G RHO rhodopsin enables ISO PMID:23704327 MGI PMID:23704327 RGD:8553853 NCBI chr13:68,908,578...68,913,651
Ensembl chr13:68,908,578...68,913,651 		JBrowse link
G SAG S-antigen visual arrestin enables ISO PMID:23704327 MGI PMID:23704327 RGD:8553853 NCBI chr15:133,704,975...133,741,844
Ensembl chr15:133,705,008...133,741,798 		JBrowse link
G SLC26A5 solute carrier family 26 member 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:103,382,558...103,420,054
Ensembl chr 9:103,378,776...103,453,730 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 enables ISO PMID:23704327
(PMID:18796539)		 MGI PMID:18796539 PMID:23704327 RGD:8553853 NCBI chr 1:268,936,120...269,002,261
Ensembl chr 1:268,936,025...269,002,256 		JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:48,729,839...48,812,799
Ensembl chr 6:48,729,419...48,812,796 		JBrowse link
G SPTBN5 spectrin beta, non-erythrocytic 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:129,461,598...129,514,380
Ensembl chr 1:129,462,568...129,511,568 		JBrowse link
G UNC13A unc-13 homolog A ISO RGD PMID:9704016 RGD:70020 NCBI chr 2:60,057,926...60,130,015 JBrowse link
G USH1C USH1 protein network component harmonin enables IEA Ensembl GO_REF:0000107 NCBI chr 2:41,593,793...41,646,777
Ensembl chr 2:41,593,802...41,647,247 		JBrowse link
G USH1G USH1 protein network component sans enables IEA Ensembl GO_REF:0000107 NCBI chr12:6,333,640...6,341,083
Ensembl chr12:6,334,310...6,340,361 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18689
    binding 16248
      protein-containing complex binding 2108
        spectrin binding 31
Path 2
Term Annotations click to browse term
  molecular_function 18689
    binding 16248
      protein binding 14177
        cytoskeletal protein binding 998
          spectrin binding 31
paths to the root