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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization



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positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,749,478...64,891,653
Ensembl chr15:64,750,796...64,891,544
JBrowse link
G ACVR2A activin A receptor type 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,177,333...4,259,056
Ensembl chr15:4,173,805...4,259,706
JBrowse link
G ACVR2B activin A receptor type 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,237,699...23,276,086
Ensembl chr13:23,237,699...23,267,373
JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726)
(PMID:22419726)
UniProt PMID:22419726 MGI:6211994 NCBI chr 2:97,703,648...98,277,847
Ensembl chr 2:97,735,053...98,275,748
JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,033,579...150,040,731
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094
JBrowse link
G ANO6 anoctamin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,112,428...76,337,073
Ensembl chr 5:76,113,236...76,337,069
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:92,935,688...93,061,406
Ensembl chr 5:92,935,694...93,061,405
JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:111,914,710...111,919,766
Ensembl chr 3:111,914,708...111,919,946
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:14749725) RGD
Ensembl
MGI
PMID:14749725 PMID:15352071 GO_REF:0000107 RGD:9068399 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,956...57,675,986
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:87,743,270...87,891,790
Ensembl chr14:87,742,459...87,891,790
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:124,536,648...125,035,841
Ensembl chr 8:124,536,653...124,759,406
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:105,971,577...106,132,496
Ensembl chr15:105,970,428...106,135,730
JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,392,404...130,395,179
Ensembl chr 4:130,392,407...130,395,150
JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chr 7:59,703,283...59,733,910
Ensembl chr 7:59,703,289...59,733,777
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr 3:159,107...200,462
Ensembl chr 3:163,421...200,459
JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:131,150,665...131,370,241
Ensembl chr 2:131,152,127...131,370,881
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 8:879,151...894,968
Ensembl chr 8:879,159...894,964
JBrowse link
G FZD9 frizzled class receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,753,294...10,762,812
Ensembl chr 3:10,754,783...10,757,147
JBrowse link
G GPM6B glycoprotein M6B involved_in ISO (PMID:21638316) UniProt PMID:21638316 NCBI chr  X:10,429,496...10,582,768
Ensembl chr  X:10,430,301...10,582,354
JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:63,363,201...63,364,211
Ensembl chr 6:63,363,173...63,364,208
JBrowse link
G KL klotho involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:9,427,236...9,479,251
Ensembl chr11:9,427,037...9,479,228
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:96,122,407...96,296,927
Ensembl chr 2:96,124,168...96,296,810
JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr10:11,362,489...11,428,844
Ensembl chr10:11,377,846...11,429,015
JBrowse link
G NELL1 neural EGFL like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:37,809,080...38,754,520
Ensembl chr 2:37,809,008...38,754,525
JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:118,368,471...118,765,107
Ensembl chr 3:118,757,920...118,765,102
JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:37,890,200...37,897,935
Ensembl chr 4:37,890,203...37,897,929
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12677010), (PMID:18519738) Ensembl
MGI
PMID:12677010 PMID:18519738 GO_REF:0000107 NCBI chr14:31,415,188...31,476,502
Ensembl chr14:31,415,193...31,476,472
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:98,258,456...98,268,539
Ensembl chr 3:98,258,463...98,268,553
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr 9:127,853,581...128,164,825
Ensembl chr 9:127,859,051...128,162,638
JBrowse link
G PTH parathyroid hormone involved_in ISO
IEA
RGD
Ensembl
PMID:15758479 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chr 2:45,757,398...45,760,433
Ensembl chr 2:45,757,398...45,760,415
JBrowse link
G PTN pleiotrophin involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,787...12,309,044
JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:11,435,435...11,549,623
Ensembl chr17:11,435,442...11,486,581
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:99,823,503...100,257,306
Ensembl chr 3:99,897,162...100,244,759
JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:84,545,033...84,552,138
Ensembl chr 1:84,545,202...84,552,134
JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:7,221,654...7,244,626
Ensembl chr 7:7,221,656...7,244,612
JBrowse link
G TMEM119 transmembrane protein 119 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:42,190,958...42,197,384 JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15728361) Ensembl
MGI
PMID:15728361 GO_REF:0000107 NCBI chr 5:14,997,377...15,013,928
Ensembl chr 5:14,997,381...15,003,567
JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chr 6:80,110,238...80,138,165 JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,860,386...5,873,779
Ensembl chr 2:5,860,391...5,874,124
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr 3:113,044,788...113,184,809
Ensembl chr 3:113,044,836...113,180,742
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195
JBrowse link
G LTF lactotransferrin involved_in ISS UniProt GO_REF:0000024 NCBI chr13:29,413,886...29,445,751
Ensembl chr13:29,413,886...29,445,739
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17651
    developmental process 6662
      positive regulation of developmental process 1516
        positive regulation of biomineral tissue development 57
          positive regulation of bone mineralization 47
            positive regulation of bone mineralization involved in bone maturation 4
Path 2
Term Annotations click to browse term
  biological_process 17651
    biological regulation 12804
      regulation of biological process 12429
        regulation of multicellular organismal process 3200
          regulation of multicellular organismal development 1600
            regulation of biomineral tissue development 104
              positive regulation of biomineral tissue development 57
                positive regulation of bone mineralization 47
                  positive regulation of bone mineralization involved in bone maturation 4
paths to the root