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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization

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positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624732:7,929,997...8,004,235
Ensembl chrNW_004624732:7,929,583...8,005,072 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624866:539,967...619,575
Ensembl chrNW_004624866:539,894...620,302 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624731:2,557,993...2,600,250
Ensembl chrNW_004624731:2,566,063...2,600,035 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726)
(PMID:22419726)		 UniProt PMID:22419726 MGI:6211994 NCBI chrNW_004624743:9,849,070...10,292,392 JBrowse link
G Adrb2 adrenoceptor beta 2 acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chrNW_004624774:8,211,723...8,215,962
Ensembl chrNW_004624774:8,211,984...8,213,240 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 UniProt PMID:25589784 MGI:5634871 NCBI chrNW_004624816:6,896,176...7,077,758
Ensembl chrNW_004624816:6,894,413...7,077,883 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISO (MGI:5780494|PMID:26392310)
(PMID:26392310)		 UniProt PMID:26392310 MGI:5780494 NCBI chrNW_004624750:16,990,288...17,103,279 JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004624738:9,311,746...9,318,099
Ensembl chrNW_004624738:9,311,836...9,317,861 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (MGI:5009350|PMID:20675382)
(PMID:18436533), (PMID:20576608)		 BHF-UCL PMID:18436533 PMID:20576608 PMID:20675382 MGI:5009350 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:14749725), (PMID:18436533) RGD
UniProt
MGI		 PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624756:17,742,822...17,894,931
Ensembl chrNW_004624756:17,743,834...17,894,753 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624841:218,642...304,744
Ensembl chrNW_004624841:219,133...265,397 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624757:22,697,639...23,142,209
Ensembl chrNW_004624757:22,955,666...23,142,499 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624765:13,849,689...13,950,839
Ensembl chrNW_004624765:13,857,062...13,947,683 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004624742:11,882,815...11,885,686
Ensembl chrNW_004624742:11,882,907...11,885,667 		JBrowse link
G Cd276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chrNW_004624781:691,348...703,202 JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chrNW_004624774:9,363,156...9,391,939
Ensembl chrNW_004624774:9,363,908...9,391,986 		JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17369251), (PMID:22615579) Ensembl
MGI		 PMID:17369251 PMID:22615579 GO_REF:0000107 NCBI chrNW_004624740:25,984,642...26,032,089
Ensembl chrNW_004624740:25,984,091...26,032,649 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508)
(PMID:20855508)		 BHF-UCL PMID:20855508 MGI:4836762 NCBI chrNW_004624774:12,863,446...13,116,929
Ensembl chrNW_004624774:12,863,446...13,116,545 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004624755:25,633,690...25,647,361
Ensembl chrNW_004624755:25,635,165...25,646,932 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004624740:14,323,445...14,325,616
Ensembl chrNW_004624740:14,323,817...14,325,601 		JBrowse link
G Gpm6b glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624882:220,267...374,912
Ensembl chrNW_004624882:220,362...374,912 		JBrowse link
G Isg15 ISG15 ubiquitin like modifier involved_in ISO (MGI:4943600|PMID:21402791)
(PMID:21402791)		 UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004624818:8,510,657...8,511,749 JBrowse link
G Kl klotho involved_in ISO (PMID:12110410) UniProt PMID:12110410 NCBI chrNW_004624915:95,155...110,834 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706)
(PMID:21652706)		 UniProt PMID:21652706 MGI:5285459 NCBI chrNW_004624743:8,072,871...8,235,174
Ensembl chrNW_004624743:8,072,673...8,235,252 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004624766:11,921,570...12,734,032
Ensembl chrNW_004624766:11,921,650...12,737,576 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO (MGI:4950000|PMID:21262216)
(PMID:21262216)		 BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004624738:2,136,228...2,559,092
Ensembl chrNW_004624738:2,136,151...2,138,441 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624763:6,035,923...6,043,682
Ensembl chrNW_004624763:6,035,953...6,043,437 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chrNW_004624738:23,759,382...23,768,743
Ensembl chrNW_004624738:23,759,398...23,771,639 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chrNW_004624814:6,597,248...6,744,294
Ensembl chrNW_004624814:6,597,005...6,744,286 		JBrowse link
G Pth parathyroid hormone involved_in ISO
IEA		 RGD
Ensembl		 PMID:15758479 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chrNW_004624766:5,489,857...5,492,777
Ensembl chrNW_004624766:5,489,800...5,492,871 		JBrowse link
G Ptn pleiotrophin involved_in ISO (MGI:6294181|PMID:19442624)
(PMID:19442624)		 UniProt PMID:19442624 MGI:6294181 NCBI chrNW_004624765:17,523,086...17,625,264
Ensembl chrNW_004624765:17,522,916...17,548,184 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 involved_in ISO (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chrNW_004624780:725,992...833,419
Ensembl chrNW_004624780:779,900...832,137 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) UniProt PMID:25589784 NCBI chrNW_004624738:21,648,277...22,026,385
Ensembl chrNW_004624738:21,651,489...21,939,927 		JBrowse link
G Smad3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chrNW_004624781:5,795,652...5,890,047
Ensembl chrNW_004624781:5,795,652...5,890,371 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (MGI:6717031|PMID:33882302) UniProt PMID:33882302 MGI:6717031 NCBI chrNW_004624799:12,829,562...12,836,850
Ensembl chrNW_004624799:12,829,528...12,834,511 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chrNW_004624756:15,413,950...15,436,037
Ensembl chrNW_004624756:15,418,260...15,436,379 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:11,828,292...11,834,855 JBrowse link
G Wnt10b Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728361) Ensembl
MGI		 PMID:15728361 GO_REF:0000107 NCBI chrNW_004624816:3,221,573...3,227,102
Ensembl chrNW_004624816:3,210,828...3,227,096 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chrNW_004624767:19,844,996...19,859,274
Ensembl chrNW_004624767:19,844,884...19,858,950 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chrNW_004624738:7,958,610...8,100,223
Ensembl chrNW_004624738:7,603,252...8,100,369 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15258
    developmental process 6204
      positive regulation of developmental process 1385
        positive regulation of biomineral tissue development 55
          positive regulation of bone mineralization 45
            positive regulation of bone mineralization involved in bone maturation 3
Path 2
Term Annotations click to browse term
  biological_process 15258
    biological regulation 10796
      regulation of biological process 10451
        regulation of multicellular organismal process 2915
          regulation of multicellular organismal development 1464
            regulation of biomineral tissue development 101
              positive regulation of biomineral tissue development 55
                positive regulation of bone mineralization 45
                  positive regulation of bone mineralization involved in bone maturation 3
paths to the root