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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization


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positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor, type 1 involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 2:58,336,450...58,456,840
Ensembl chr 2:58,278,656...58,457,169 		JBrowse link
G Acvr2a activin receptor IIA involved_in ISO
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 2:48,704,121...48,793,276
Ensembl chr 2:48,704,121...48,793,281 		JBrowse link
G Acvr2b activin receptor IIB involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in IMP (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chr13:81,243,187...81,781,504
Ensembl chr13:81,243,187...81,781,273 		JBrowse link
G Adrb2 adrenergic receptor, beta 2 acts_upstream_of_or_within IMP (PMID:15724149) MGI PMID:15724149 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IMP (MGI:6393219|PMID:24906289)
(PMID:24906289)		 UniProt PMID:24906289 MGI:6393219 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Ano6 anoctamin 6 involved_in IMP
ISO		 (MGI:5634871|PMID:25589784) UniProt
MGI		 PMID:25589784 GO_REF:0000119 MGI:4834177 MGI:5634871 NCBI chr15:95,688,724...95,873,353
Ensembl chr15:95,688,724...95,872,632 		JBrowse link
G Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 involved_in IMP (MGI:5780494|PMID:26392310)
(PMID:26392310)		 UniProt PMID:26392310 MGI:5780494 NCBI chr10:98,750,243...98,862,005
Ensembl chr10:98,750,268...98,862,005 		JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in ISO
ISS		 MGI
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 5:31,205,984...31,211,977
Ensembl chr 5:31,205,656...31,211,967 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IDA
ISO		 (MGI:5009350|PMID:20675382) BHF-UCL
MGI		 PMID:20675382 GO_REF:0000119 MGI:4834177 MGI:5009350 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 ISO
ISS		 RGD
MGI
GO_Central
UniProt		 PMID:15352071 GO_REF:0000008 GO_REF:0000024 GO_REF:0000096 GO_REF:0000119 MGI:4417868 RGD:9068399 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO
IEA		 MGI
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr13:38,529,098...38,684,283
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor, type 1A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:34,133,018...34,225,335
Ensembl chr14:34,132,691...34,225,298 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor, type 1B involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 3:141,540,230...141,875,335
Ensembl chr 3:141,542,897...141,875,186 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 1:59,802,721...59,917,240
Ensembl chr 1:59,802,559...59,918,173 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736 		JBrowse link
G Cd276 CD276 antigen acts_upstream_of_or_within IMP (PMID:15317945) MGI PMID:15317945 NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in ISO RGD
MGI
GO_Central		 PMID:18434589 GO_REF:0000096 MGI:4417868 RGD:151665814 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within IDA (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr 5:138,740,836...138,795,818
Ensembl chr 5:138,740,269...138,795,832 		JBrowse link
G Fbn2 fibrillin 2 involved_in IMP (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chr18:58,141,689...58,343,200
Ensembl chr18:58,141,695...58,343,559 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within IMP (PMID:20053668) MGI PMID:20053668 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in IMP (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chr 5:135,277,792...135,279,901
Ensembl chr 5:135,277,792...135,280,084 		JBrowse link
G Gpm6b glycoprotein m6b involved_in ISO
ISS		 MGI
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr  X:165,021,911...165,172,028
Ensembl chr  X:165,021,907...165,171,984 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in IMP (MGI:4943600|PMID:21402791)
(PMID:21402791)		 UniProt PMID:21402791 MGI:4943600 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253 		JBrowse link
G Kl klotho involved_in ISO
IEA		 MGI
GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 5:150,876,072...150,917,282
Ensembl chr 5:150,876,072...150,917,282 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP (MGI:5285459|PMID:21652706)
(PMID:21652706)		 UniProt PMID:21652706 MGI:5285459 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within IMP (PMID:21606205) MGI PMID:21606205 NCBI chr 1:183,107,091...183,151,091
Ensembl chr 1:183,107,682...183,150,894 		JBrowse link
G Nell1 NEL-like 1 involved_in ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr 7:49,625,098...50,513,037
Ensembl chr 7:49,624,612...50,516,356 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in IGI (MGI:4950000|PMID:21262216)
(PMID:21262216)		 BHF-UCL PMID:21262216 MGI:4950000 NCBI chr12:9,624,442...9,631,500
Ensembl chr12:9,620,116...9,631,500 		JBrowse link
G Osr2 odd-skipped related 2 involved_in IGI (MGI:4950000|PMID:21262216)
(PMID:21262216)		 BHF-UCL PMID:21262216 MGI:4950000 NCBI chr15:35,296,244...35,303,451
Ensembl chr15:35,296,244...35,303,451 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 acts_upstream_of_or_within IMP (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in IMP (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chr17:83,522,708...83,532,496
Ensembl chr17:83,522,721...83,532,499 		JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) ISO RGD PMID:10807497 RGD:1642474 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041 		JBrowse link
G Pth parathyroid hormone involved_in ISO RGD
MGI		 PMID:15758479 PMID:22445539 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:7207452 RGD:7242906 NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777 		JBrowse link
G Ptn pleiotrophin involved_in IMP (MGI:6294181|PMID:19442624) UniProt PMID:19442624 MGI:6294181 NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155 		JBrowse link
G Rxra retinoid X receptor alpha involved_in NAS (MGI:6219233|PMID:27184385) ComplexPortal PMID:27184385 MGI:6219233 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G Rxrb retinoid X receptor beta involved_in NAS (MGI:6219233|PMID:27184385) ComplexPortal PMID:27184385 MGI:6219233 NCBI chr17:34,250,786...34,257,377
Ensembl chr17:34,250,786...34,257,373 		JBrowse link
G Slc20a2 solute carrier family 20, member 2 involved_in IMP (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chr 8:22,966,771...23,059,632
Ensembl chr 8:22,966,804...23,059,628 		JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD
GO_Central
MGI		 PMID:12096832 GO_REF:0000096 MGI:4417868 RGD:727387 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in IMP (MGI:6717031|PMID:33882302) UniProt PMID:33882302 MGI:6717031 NCBI chr 9:85,202,492...85,209,203
Ensembl chr 9:85,202,492...85,209,401 		JBrowse link
G Tfap2a transcription factor AP-2, alpha involved_in ISO
ISS		 MGI
GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 MGI:4834177 NCBI chr13:40,867,278...40,891,715
Ensembl chr13:40,868,778...40,891,852 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in IMP
IBA
ISO		 (MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632) UniProt
GO_Central
MGI		 PMID:20025746 PMID:26207632 GO_REF:0000033 GO_REF:0000119 MGI:4418582 MGI:4834177 MGI:5700277 NCBI chr 5:113,931,790...113,938,457
Ensembl chr 5:113,931,790...113,938,577 		JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor involved_in NAS (MGI:6219233|PMID:27184385)
(PMID:27184385)		 ComplexPortal PMID:27184385 MGI:6219233 NCBI chr15:97,752,308...97,806,177
Ensembl chr15:97,752,306...97,808,511 		JBrowse link
G Wnt10b wingless-type MMTV integration site family, member 10B acts_upstream_of_or_within IDA (PMID:15728361) MGI PMID:15728361 NCBI chr15:98,668,593...98,676,093
Ensembl chr15:98,668,593...98,676,031 		JBrowse link
G Wnt4 wingless-type MMTV integration site family, member 4 involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 4:137,004,946...137,026,812
Ensembl chr 4:137,004,800...137,027,037 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IMP (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chr19:4,911,244...4,927,937
Ensembl chr19:4,911,244...4,927,937 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within IMP (PMID:21490954) MGI PMID:21490954 NCBI chr12:3,476,892...3,560,811
Ensembl chr12:3,476,857...3,556,852 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 MGI
Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 MGI:4834177 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805 		JBrowse link
G Ltf lactotransferrin involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28753
    developmental process 7483
      positive regulation of developmental process 1654
        positive regulation of biomineral tissue development 60
          positive regulation of bone mineralization 50
            positive regulation of bone mineralization involved in bone maturation 4
Path 2
Term Annotations click to browse term
  biological_process 28753
    biological regulation 13498
      regulation of biological process 13070
        regulation of multicellular organismal process 3542
          regulation of multicellular organismal development 1755
            regulation of biomineral tissue development 113
              positive regulation of biomineral tissue development 60
                positive regulation of bone mineralization 50
                  positive regulation of bone mineralization involved in bone maturation 4
paths to the root