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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization


show annotations for term's descendants           Sort by:
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IMP (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in IMP (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr 2:147,844,517...147,930,822
Ensembl chr 2:147,844,517...147,930,826 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in IMP (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142 		JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:90,558,797...91,164,437
Ensembl chr 5:90,529,344...91,164,437 		JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15724149) Ensembl
MGI		 PMID:15724149 GO_REF:0000107 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANO6 anoctamin 6 involved_in IMP (PMID:25589784) UniProt PMID:25589784 NCBI chr12:45,216,095...45,440,404
Ensembl chr12:45,215,987...45,482,280 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366 		JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IDA (PMID:21723284) UniProt PMID:21723284 NCBI chr 2:27,212,041...27,217,183
Ensembl chr 2:27,212,041...27,217,178 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IDA
IEA		 (PMID:18436533), (PMID:20576608) BHF-UCL
Ensembl		 PMID:18436533 PMID:20576608 GO_REF:0000107 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO
IDA		 (PMID:14749725)
(PMID:14749725), (PMID:18436533)		 RGD
MGI
UniProt		 PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IDA (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IDA (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IMP (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr10:86,755,763...86,932,844
Ensembl chr10:86,755,786...86,932,825 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IMP (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IMP (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G CCN1 cellular communication network factor 1 involved_in IDA (PMID:20675382) BHF-UCL PMID:20675382 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chr15:73,683,944...73,714,514
Ensembl chr15:73,683,966...73,714,514 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372 		JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17369251), (PMID:22615579) Ensembl
MGI		 PMID:17369251 PMID:22615579 GO_REF:0000107 NCBI chr 7:192,571...260,772
Ensembl chr 7:192,571...260,772 		JBrowse link
G FBN2 fibrillin 2 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:128,257,909...128,538,245
Ensembl chr 5:128,257,909...128,659,185 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872 		JBrowse link
G FZD9 frizzled class receptor 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:73,433,778...73,436,120
Ensembl chr 7:73,433,778...73,436,120 		JBrowse link
G GPM6B glycoprotein M6B involved_in IMP (PMID:21638316) UniProt PMID:21638316 NCBI chr  X:13,770,939...13,938,638
Ensembl chr  X:13,770,939...13,938,638 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:1,013,497...1,014,540
Ensembl chr 1:1,001,138...1,014,540 		JBrowse link
G KL klotho involved_in IMP (PMID:12110410) UniProt PMID:12110410 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:88,717,117...88,904,105
Ensembl chr 5:88,717,117...88,904,257 		JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr 1:222,618,097...222,668,007
Ensembl chr 1:222,618,097...222,668,007 		JBrowse link
G NELL1 neural EGFL like 1 involved_in IDA (PMID:21723284) UniProt PMID:21723284 NCBI chr11:20,669,551...21,575,686
Ensembl chr11:20,669,551...21,575,686 		JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:19,344,874...19,358,623
Ensembl chr 2:19,351,485...19,358,623 		JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA
ISS		 Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:98,944,442...98,952,100
Ensembl chr 8:98,944,403...98,952,104 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 (PMID:12677010), (PMID:18519738) BHF-UCL
Ensembl
MGI		 PMID:12677010 PMID:18519738 GO_REF:0000024 GO_REF:0000107 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032 		JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:42,048,021...42,058,517
Ensembl chr 2:42,048,021...42,058,517 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr 1:186,828,949...186,988,981
Ensembl chr 1:186,828,949...186,988,981 		JBrowse link
G PTH parathyroid hormone involved_in ISO
IDA
IEA		 (PMID:17696759) RGD
UniProt
Ensembl		 PMID:15758479 PMID:17696759 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G PTN pleiotrophin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774 		JBrowse link
G RXRA retinoid X receptor alpha involved_in NAS (PMID:27184385) ComplexPortal PMID:27184385 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585 		JBrowse link
G RXRB retinoid X receptor beta involved_in NAS (PMID:27184385) ComplexPortal PMID:27184385 NCBI chr 6:33,193,588...33,200,853
Ensembl chr 6:33,193,588...33,200,665 		JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:42,416,475...42,541,954
Ensembl chr 8:42,416,475...42,541,926 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IMP (PMID:25589784) UniProt PMID:25589784 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053 		JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO
IEA		 rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD
Ensembl		 PMID:12096832 GO_REF:0000107 RGD:727387 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in IDA (PMID:19578371) UniProt PMID:19578371 NCBI chr 6:10,396,677...10,419,659
Ensembl chr 6:10,393,186...10,419,659 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in IDA
IBA
IEA		 (PMID:20025746) UniProt
GO_Central
Ensembl		 PMID:20025746 GO_REF:0000033 GO_REF:0000107 NCBI chr12:108,589,851...108,598,084
Ensembl chr12:108,589,851...108,598,320 		JBrowse link
G VDR vitamin D receptor involved_in NAS (PMID:27184385) ComplexPortal PMID:27184385 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728361) Ensembl
MGI		 PMID:15728361 GO_REF:0000107 NCBI chr12:48,965,340...48,971,735
Ensembl chr12:48,965,340...48,971,735 		JBrowse link
G WNT4 Wnt family member 4 involved_in IDA (PMID:17720811) BHF-UCL PMID:17720811 NCBI chr 1:22,117,313...22,143,097
Ensembl chr 1:22,117,313...22,143,969 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:66,546,395...66,563,334
Ensembl chr11:66,546,395...66,563,334 		JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr 2:25,733,753...25,878,487
Ensembl chr 2:25,733,753...25,878,487 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IDA (PMID:16433617) BHF-UCL PMID:16433617 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G LTF lactotransferrin involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19789
    developmental process 7649
      positive regulation of developmental process 1663
        positive regulation of biomineral tissue development 61
          positive regulation of bone mineralization 50
            positive regulation of bone mineralization involved in bone maturation 4
Path 2
Term Annotations click to browse term
  biological_process 19789
    biological regulation 13533
      regulation of biological process 13133
        regulation of multicellular organismal process 3558
          regulation of multicellular organismal development 1774
            regulation of biomineral tissue development 114
              positive regulation of biomineral tissue development 61
                positive regulation of bone mineralization 50
                  positive regulation of bone mineralization involved in bone maturation 4
paths to the root