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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization


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positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr10:43,139,396...43,281,024
Ensembl chr10:43,139,528...43,281,177
JBrowse link
G ACVR2A activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr10:33,223,902...33,311,257
Ensembl chr10:33,224,099...33,307,720
JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr15:923,222...962,438 JBrowse link
G ACVR2B activin A receptor type 2B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:933,070...939,419 JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chr 4:84,498,630...85,082,813
Ensembl chr 4:84,498,573...85,083,504
JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331
JBrowse link
G ANO6 anoctamin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:41,420,206...41,633,323
Ensembl chr11:41,419,901...41,633,347
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:84,985,957...85,053,923
Ensembl chr11:84,989,169...85,103,957
JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:80,399,298...80,404,539
Ensembl chr14:80,399,513...80,404,280
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
ISO (PMID:14749725), (PMID:18436533) RGD
UniProt
MGI
PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,944,463...45,108,832
Ensembl chr 9:44,941,460...45,027,275
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:43,349,364...43,397,745 JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:88,103,442...88,302,578
Ensembl chr10:88,106,072...88,303,734
JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:47,783,270...47,786,216
Ensembl chr20:47,783,935...47,785,997
JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chr26:9,772,948...9,794,395 JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304
JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:31,204,652...31,476,677
Ensembl chr23:31,204,391...31,475,820
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392
JBrowse link
G FZD9 frizzled class receptor 9 involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chr28:9,621,434...9,623,769
Ensembl chr28:9,621,770...9,623,545
JBrowse link
G GPM6B glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:12,258,386...12,429,883 JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chr20:130,419,909...130,421,409
Ensembl chr20:130,419,782...130,421,380
JBrowse link
G KL klotho involved_in ISO (PMID:12110410) UniProt PMID:12110410 NCBI chr 3:11,755,015...11,799,537
Ensembl chr 3:11,755,016...11,797,596
JBrowse link
G LOC103246914 FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr28:21,299,235...21,371,603
Ensembl chr28:21,299,213...21,371,577
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152
JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr25:6,901,891...6,954,556
Ensembl chr25:6,902,425...6,954,526
JBrowse link
G NELL1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chr 1:43,416,052...44,335,894
Ensembl chr 1:43,415,553...44,335,381
JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,364,115...88,371,258
Ensembl chr14:88,364,166...88,371,263
JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:93,831,218...93,839,098
Ensembl chr 8:93,831,480...93,839,263
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chr14:65,203,757...65,214,386
Ensembl chr14:65,204,620...65,214,190
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431
JBrowse link
G PTH parathyroid hormone involved_in ISO (PMID:17696759) RGD
UniProt
PMID:15758479 PMID:17696759 PMID:22445539 RGD:7207452 RGD:7242906 NCBI chr 1:51,327,555...51,330,810 JBrowse link
G PTN pleiotrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215
JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:40,413,070...40,535,002
Ensembl chr 8:40,412,958...40,469,896
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) UniProt PMID:25589784 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr14:66,871,034...66,970,731 JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:6,392,131...6,399,456
Ensembl chr13:6,392,025...6,398,564
JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr17:61,750,757...61,769,041 JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:103,787,911...103,796,217
Ensembl chr11:103,788,407...103,789,249
JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361) MGI PMID:15728361 NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893
JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203
JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chr 1:7,708,595...7,724,634
Ensembl chr 1:7,705,725...7,724,589
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr14:81,770,068...81,919,200 JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17098
    developmental process 6699
      positive regulation of developmental process 1473
        positive regulation of biomineral tissue development 59
          positive regulation of bone mineralization 49
            positive regulation of bone mineralization involved in bone maturation 3
Path 2
Term Annotations click to browse term
  biological_process 17098
    biological regulation 11811
      regulation of biological process 11423
        regulation of multicellular organismal process 3163
          regulation of multicellular organismal development 1559
            regulation of biomineral tissue development 110
              positive regulation of biomineral tissue development 59
                positive regulation of bone mineralization 49
                  positive regulation of bone mineralization involved in bone maturation 3
paths to the root