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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization



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positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652
JBrowse link
G ACVR2A activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420
JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894
JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726)
(PMID:22419726)
UniProt PMID:22419726 MGI:6211994 NCBI chr 3:17,866,459...18,351,532
Ensembl chr 3:17,866,808...18,351,532
JBrowse link
G ADRB2 adrenoceptor beta 2 acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298
JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in IEA Ensembl GO_REF:0000107
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609
JBrowse link
G ANO6 anoctamin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:30,547,009...30,674,094
Ensembl chr15:30,547,015...30,616,429
JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:21,193,685...21,198,897
Ensembl chr17:21,193,909...21,198,718
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:14749725) RGD
Ensembl
MGI
PMID:14749725 PMID:15352071 GO_REF:0000107 RGD:9068399 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024
JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994
JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924
JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr 6:16,448,603...16,497,064
Ensembl chr 6:16,448,588...16,497,752
JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,311,238...17,551,536
Ensembl chr11:17,311,226...17,551,536
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896
JBrowse link
G FZD9 frizzled class receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,782,394...6,784,565
Ensembl chr 6:6,782,774...6,784,558
JBrowse link
G GPM6B glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:10,214,889...10,375,151
Ensembl chr  X:10,214,933...10,374,837
JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,230,879...56,237,354
Ensembl chr 5:56,236,318...56,404,695
JBrowse link
G KL klotho involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:7,154,359...7,201,744
Ensembl chr25:7,156,620...7,199,558
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706)
(PMID:21652706)
UniProt PMID:21652706 MGI:5285459 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852
JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr38:16,880,411...16,936,368
Ensembl chr38:16,879,740...16,935,844
JBrowse link
G NELL1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chr21:42,654,925...43,468,806
Ensembl chr21:42,656,339...43,468,806
JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,508,543...14,515,657
Ensembl chr17:14,509,333...14,589,228
JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:1,019,167...1,031,622
Ensembl chr13:1,023,879...1,031,225
JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12677010), (PMID:18519738) Ensembl
MGI
PMID:12677010 PMID:18519738 GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892
JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936
JBrowse link
G PTH parathyroid hormone involved_in ISO
IEA
RGD
Ensembl
PMID:15758479 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967
JBrowse link
G PTN pleiotrophin involved_in ISO (MGI:6294181|PMID:19442624)
(PMID:19442624)
UniProt PMID:19442624 MGI:6294181 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814
JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in ISO (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chr16:23,165,347...23,268,115
Ensembl chr16:23,200,798...23,267,775
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700
JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:42,270,029...42,277,905
Ensembl chr12:42,274,000...42,277,513
JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270
JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,275,719...18,282,905
Ensembl chr26:18,260,923...18,282,409
JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15728361) Ensembl
MGI
PMID:15728361 GO_REF:0000107 NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501
JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111
JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17088
    developmental process 6554
      positive regulation of developmental process 1516
        positive regulation of biomineral tissue development 57
          positive regulation of bone mineralization 47
            positive regulation of bone mineralization involved in bone maturation 3
Path 2
Term Annotations click to browse term
  biological_process 17088
    biological regulation 11828
      regulation of biological process 11474
        regulation of multicellular organismal process 3222
          regulation of multicellular organismal development 1611
            regulation of biomineral tissue development 106
              positive regulation of biomineral tissue development 57
                positive regulation of bone mineralization 47
                  positive regulation of bone mineralization involved in bone maturation 3
paths to the root