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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of bone mineralization
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Accession:GO:0030501 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: up regulation of bone mineralization;   upregulation of bone mineralization
 narrow_synonym: activation of bone mineralization;   stimulation of bone mineralization

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positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955440:13,849,926...13,931,374
Ensembl chrNW_004955440:13,849,926...13,931,374 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955427:25,438,652...25,467,360
Ensembl chrNW_004955427:25,438,652...25,467,360 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726)
(PMID:22419726)		 UniProt PMID:22419726 MGI:6211994 NCBI chrNW_004955418:20,603,323...21,039,891 JBrowse link
G Adrb2 adrenoceptor beta 2 acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in ISO (MGI:6393219|PMID:24906289)
(PMID:24906289)		 UniProt PMID:24906289 MGI:6393219 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 UniProt PMID:25589784 MGI:5634871 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISO (MGI:5780494|PMID:26392310)
(PMID:26392310)		 UniProt PMID:26392310 MGI:5780494 NCBI chrNW_004955405:26,872,379...26,932,270
Ensembl chrNW_004955405:26,872,379...26,932,703 		JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004955469:9,194,656...9,203,292 JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:18436533), (PMID:20576608)
(MGI:5009350|PMID:20675382)		 BHF-UCL PMID:18436533 PMID:20576608 PMID:20675382 MGI:5009350 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO (PMID:14749725)
(PMID:14749725), (PMID:18436533)		 RGD
MGI		 PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955405:5,408,171...5,784,930
Ensembl chrNW_004955405:5,700,162...5,787,957 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Cd276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chrNW_004955450:3,884,437...3,896,416 JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751 		JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chrNW_004955460:8,142,325...8,192,044
Ensembl chrNW_004955460:8,143,824...8,193,825 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508)
(PMID:20855508)		 BHF-UCL PMID:20855508 MGI:4836762 NCBI chrNW_004955415:1,307,553...1,535,435
Ensembl chrNW_004955415:1,309,077...1,537,052 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004955456:14,245,994...14,247,551
Ensembl chrNW_004955456:14,246,324...14,247,550 		JBrowse link
G Gpm6b glycoprotein M6B involved_in ISO (PMID:21638316) UniProt PMID:21638316 NCBI chrNW_004955519:4,287,203...4,432,188
Ensembl chrNW_004955519:4,287,026...4,432,188 		JBrowse link
G Isg15 ISG15 ubiquitin like modifier involved_in ISO (MGI:4943600|PMID:21402791)
(PMID:21402791)		 UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004955486:9,706,878...9,707,876
Ensembl chrNW_004955486:9,706,703...9,707,949 		JBrowse link
G Kl klotho involved_in ISO (PMID:12110410) UniProt PMID:12110410 NCBI chrNW_004955431:12,782,913...12,833,215
Ensembl chrNW_004955431:12,782,846...12,833,215 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706)
(PMID:21652706)		 UniProt PMID:21652706 MGI:5285459 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chrNW_004955520:1,853,145...1,890,338
Ensembl chrNW_004955520:1,850,942...1,890,390 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004955476:1,445,234...2,236,954
Ensembl chrNW_004955476:1,445,353...2,233,146 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO (MGI:4950000|PMID:21262216)
(PMID:21262216)		 BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004955469:1,954,470...1,961,344
Ensembl chrNW_004955469:1,953,370...1,961,390 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in ISO (MGI:4950000|PMID:21262216)
(PMID:21262216)		 BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004955417:14,502,450...14,510,015
Ensembl chrNW_004955417:14,502,451...14,510,160 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chrNW_004955441:9,462,530...9,471,446
Ensembl chrNW_004955441:9,462,530...9,471,446 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chrNW_004955406:25,257,361...25,392,079
Ensembl chrNW_004955406:25,257,355...25,394,206 		JBrowse link
G Pth parathyroid hormone involved_in ISO (PMID:17696759) RGD
UniProt		 PMID:15758479 PMID:17696759 PMID:22445539 RGD:7207452 RGD:7242906 NCBI chrNW_004955414:28,828,389...28,831,417
Ensembl chrNW_004955414:28,825,651...28,831,117 		JBrowse link
G Ptn pleiotrophin involved_in ISO (MGI:6294181|PMID:19442624)
(PMID:19442624)		 UniProt PMID:19442624 MGI:6294181 NCBI chrNW_004955494:5,580,264...5,681,848
Ensembl chrNW_004955494:5,580,422...5,684,190 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 involved_in ISO (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chrNW_004955536:392,341...496,616
Ensembl chrNW_004955536:392,525...495,265 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) UniProt PMID:25589784 NCBI chrNW_004955441:7,653,107...8,037,784
Ensembl chrNW_004955441:7,656,031...7,957,640 		JBrowse link
G Smad3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (MGI:6717031|PMID:33882302) UniProt PMID:33882302 MGI:6717031 NCBI chrNW_004955411:9,695,149...9,701,463
Ensembl chrNW_004955411:9,699,011...9,701,507 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chrNW_004955465:3,877,896...3,900,259
Ensembl chrNW_004955465:3,882,549...3,898,929 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (PMID:20025746)
(PMID:20025746), (PMID:26207632)
(MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632)		 UniProt PMID:20025746 PMID:26207632 MGI:4418582 MGI:5700277 NCBI chrNW_004955455:9,856,443...9,863,100
Ensembl chrNW_004955455:9,856,443...9,863,100 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361) MGI PMID:15728361 NCBI chrNW_004955500:7,782,782...7,800,281
Ensembl chrNW_004955500:7,782,782...7,788,309 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chrNW_004955422:18,799,372...18,812,458
Ensembl chrNW_004955422:18,799,372...18,812,711 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chrNW_004955469:7,786,030...7,923,739
Ensembl chrNW_004955469:7,786,154...7,923,500 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12533
    developmental process 5919
      positive regulation of developmental process 1361
        positive regulation of biomineral tissue development 56
          positive regulation of bone mineralization 46
            positive regulation of bone mineralization involved in bone maturation 3
Path 2
Term Annotations click to browse term
  biological_process 12533
    biological regulation 9056
      regulation of biological process 8758
        regulation of multicellular organismal process 2856
          regulation of multicellular organismal development 1427
            regulation of biomineral tissue development 98
              positive regulation of biomineral tissue development 56
                positive regulation of bone mineralization 46
                  positive regulation of bone mineralization involved in bone maturation 3
paths to the root