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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of complement activation, classical pathway
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Accession:GO:0030450 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.
Synonyms:exact_synonym: regulation of complement cascade, classical pathway



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regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO MGI:2387405 (MGI:1330710|PMID:9892684) RGD PMID:9892684 MGI:1330710 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in ISO
IBA
IEA
(PMID:22333221)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:22333221 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA
(PMID:22333221)
GO_REF:0000107
RGD
Ensembl
PMID:22333221 GO_REF:0000107 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
JBrowse link
G Cd46 CD46 molecule involved_in ISO
IBA
(PMID:9029106)
PMID:21873635
RGD PMID:9029106 PMID:21873635 RGD:13792537 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Cr2 complement C3d receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235
JBrowse link
G RGD1559810 similar to hypothetical protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:33,996,404...33,997,405
Ensembl chr20:33,996,224...33,997,432
JBrowse link
G Susd4 sushi domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:23482636)
RGD PMID:23482636 PMID:21873635 RGD:13792537 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
JBrowse link
G Zp3r zona pellucida 3 receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:42,019,998...42,064,836
Ensembl chr13:42,020,018...42,064,812
JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) RGD PMID:30548312 MGI:6275756 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    immune system process 2885
      immune effector process 729
        complement activation 166
          complement activation, classical pathway 146
            regulation of complement activation, classical pathway 10
              modulation of complement activation, classical pathway in another organism + 0
              negative regulation of complement activation, classical pathway + 9
              positive regulation of complement activation, classical pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 19834
    biological regulation 13775
      regulation of biological process 13033
        regulation of immune system process 1543
          regulation of immune effector process 402
            regulation of leukocyte mediated immunity 268
              regulation of lymphocyte mediated immunity 194
                regulation of B cell mediated immunity 76
                  regulation of immunoglobulin mediated immune response 76
                    regulation of humoral immune response mediated by circulating immunoglobulin 20
                      regulation of complement activation, classical pathway 10
                        modulation of complement activation, classical pathway in another organism + 0
                        negative regulation of complement activation, classical pathway + 9
                        positive regulation of complement activation, classical pathway + 1
paths to the root