Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of complement activation
go back to main search page
Accession:GO:0030449 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of complement activation.
Synonyms:exact_synonym: regulation of complement cascade


GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
 
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101962230 complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:2,371,400...2,376,608 JBrowse link
G Phb2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004936709:854,493...859,182 JBrowse link
G Susd4 sushi domain containing 4 involved_in IEA Ensembl
InterPro
GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936526:488,604...615,265 JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule (CD59 blood group) involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050) RGD
InterPro
MGI
PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000002 MGI:1888643 MGI:2148385 RGD:1600482 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101964865 complement receptor type 1 acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:6211481)
(PMID:28657829)
RGD
UniProt
PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link
G Cd59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279) MGI PMID:10946279 MGI:1888643 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chrNW_004936578:2,804,460...2,857,731 JBrowse link
G Serping1 serpin family G member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936581:4,911,403...4,924,484 JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:10531307) UniProt PMID:10531307 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004936526:488,604...615,265 JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936635:2,167,633...2,191,725 JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpb complement component 4 binding protein beta involved_in ISO (PMID:22333221) BHF-UCL PMID:22333221 NCBI chrNW_004936557:5,546,692...5,561,531 JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chrNW_004936557:5,136,784...5,175,543 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:10531307), (PMID:6910481) UniProt PMID:6910481 PMID:10531307 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
G LOC101973539 C4b-binding protein alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936557:5,511,372...5,535,158 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chrNW_004936526:488,604...615,265 JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101959212 alpha-2-macroglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936870:424,832...468,303 JBrowse link
G Serping1 serpin family G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:4,911,403...4,924,484 JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936518:1,471,116...1,532,733 JBrowse link
G LOC101964865 complement receptor type 1 involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chrNW_004936557:5,185,831...5,284,999 JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chrNW_004936518:1,471,116...1,532,733 JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:29384235) ARUK-UCL PMID:29384235 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chrNW_004936490:12,127,065...12,138,870 JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:18,659,725...18,665,406 JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:28671664) ComplexPortal PMID:28671664 NCBI chrNW_004936588:3,985,732...4,023,221 JBrowse link
G Cfi complement factor I involved_in ISO (PMID:28671664) ComplexPortal PMID:28671664 NCBI chrNW_004936563:960,883...998,136 JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (MGI:1330710|PMID:9892684) MGI PMID:9892684 MGI:1330710 NCBI chrNW_004936557:5,344,373...5,364,234 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14954
    immune system process 2126
      activation of immune response 237
        complement activation 44
          regulation of complement activation 19
            negative regulation of complement activation + 11
            positive regulation of complement activation + 6
            regulation of activation of membrane attack complex + 4
            regulation of complement activation, alternative pathway + 6
            regulation of complement activation, classical pathway + 7
            regulation of complement activation, lectin pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 14954
    biological regulation 10655
      regulation of biological process 10116
        regulation of response to stimulus 3522
          positive regulation of response to stimulus 2001
            positive regulation of immune response 441
              activation of immune response 237
                complement activation 44
                  regulation of complement activation 19
                    negative regulation of complement activation + 11
                    positive regulation of complement activation + 6
                    regulation of activation of membrane attack complex + 4
                    regulation of complement activation, alternative pathway + 6
                    regulation of complement activation, classical pathway + 7
                    regulation of complement activation, lectin pathway + 2
paths to the root