Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of complement activation
go back to main search page
Accession:GO:0030449 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of complement activation.
Synonyms:exact_synonym: regulation of complement cascade



show annotations for term's descendants           Sort by:
 
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QBP complement C1q binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,481,114...5,487,482
Ensembl chr17:5,473,239...5,479,735
JBrowse link
G C3 complement C3 involved_in ISO (PMID:6225800) ComplexPortal PMID:6225800 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C6 complement C6 involved_in IEA UniProt GO_REF:0000117 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588
JBrowse link
G C7 complement C7 involved_in IEA UniProt GO_REF:0000117 NCBI chr 5:69,405,041...69,478,445
Ensembl chr 5:74,447,559...74,520,649
JBrowse link
G C8A complement C8 alpha chain involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:56,137,596...56,201,975
Ensembl chr 1:57,847,726...57,912,392
JBrowse link
G C8B complement C8 beta chain involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:56,213,618...56,250,488
Ensembl chr 1:57,923,720...57,960,674
JBrowse link
G C9 complement C9 involved_in IEA UniProt GO_REF:0000117 NCBI chr 5:71,011,961...71,090,243
Ensembl chr 5:76,051,911...76,130,725
JBrowse link
G CD55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) MGI PMID:25284781 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350
JBrowse link
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:25284781) MGI
Ensembl
PMID:25284781 GO_REF:0000107 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157
JBrowse link
G CD5L CD5 molecule like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5617896|PMID:25284781) MGI
Ensembl
PMID:25284781 GO_REF:0000107 MGI:5617896 NCBI chr 1:133,192,387...133,203,293
Ensembl chr 1:136,985,701...136,996,263
JBrowse link
G CFH complement factor H involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:25284781)
(MGI:3833206|PMID:18947875)
RGD
Ensembl
MGI
PMID:12374811 PMID:18947875 PMID:25284781 GO_REF:0000107 MGI:3833206 RGD:628500 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521
JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3833206|PMID:18947875)
(PMID:25284781)
MGI
Ensembl
PMID:18947875 PMID:25284781 GO_REF:0000107 MGI:3833206 NCBI chr 1:183,224,415...183,303,268
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G PHB2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) UniProt PMID:17070910 NCBI chr12:7,097,073...7,102,474
Ensembl chr12:7,013,195...7,018,053
JBrowse link
G SUSD4 sushi domain containing 4 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448
JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD59 CD59 molecule (CD59 blood group) involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050) RGD
InterPro
MGI
PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000002 MGI:1888643 MGI:2148385 RGD:1600482 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:183,094,601...183,246,957 JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:6211481)
(PMID:28657829)
RGD
UniProt
PMID:6211481 PMID:10929073 PMID:28657829 RGD:2326180 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350
JBrowse link
G CD59 CD59 molecule (CD59 blood group) acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279) MGI PMID:10946279 MGI:1888643 NCBI chr11:33,680,580...33,708,479
Ensembl chr11:33,552,164...33,590,157
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:31862673) ARUK-UCL PMID:31862673 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G CR1L complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (MGI:1351571|PMID:10642554) RGD
MGI
PMID:10642554 PMID:11861390 MGI:1351571 RGD:625470 NCBI chr 1:183,224,415...183,303,268
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G MASP1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) UniProt PMID:11485744 NCBI chr 3:184,241,611...184,317,272
Ensembl chr 3:192,707,784...192,782,196
JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:52,838,502...52,855,781
Ensembl chr11:56,309,686...56,326,639
JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307) UniProt PMID:10531307 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448
JBrowse link
G VSIG4 V-set and immunoglobulin domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:55,137,938...55,155,569
Ensembl chr  X:65,211,313...65,229,332
JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4BPA complement component 4 binding protein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898
JBrowse link
G C4BPB complement component 4 binding protein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,691,574...182,703,004
Ensembl chr 1:186,970,253...186,981,024
JBrowse link
G CD46 CD46 molecule involved_in ISO (PMID:9029106) AgBase PMID:9029106 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:10531307), (PMID:6910481) UniProt PMID:6910481 PMID:10531307 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G SUSD4 sushi domain containing 4 involved_in ISO (PMID:23482636) UniProt PMID:23482636 NCBI chr 1:198,899,771...199,043,215
Ensembl chr 1:203,911,484...204,054,448
JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100979269 alpha-2-macroglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:9,154,457...9,202,833
Ensembl chr12:9,385,359...9,433,979
JBrowse link
G SERPING1 serpin family G member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,838,502...52,855,781
Ensembl chr11:56,309,686...56,326,639
JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588
JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:11981823) ARUK-UCL PMID:11981823 NCBI chr 1:183,094,601...183,246,957 JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) BHF-UCL PMID:15611275 MGI:4430818 NCBI chr 5:69,174,411...69,245,801
Ensembl chr 5:74,216,244...74,288,588
JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
JBrowse link
G MBL2 mannose binding lectin 2 ISO RGD PMID:9920905 RGD:4889148 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432
JBrowse link
G PHB1 prohibitin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790
JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578
JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:28671664) ComplexPortal PMID:28671664 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699
JBrowse link
G CFH complement factor H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:172,155,882...172,251,632
Ensembl chr 1:176,455,247...176,525,521
JBrowse link
G CFI complement factor I involved_in ISO (PMID:28671664) ComplexPortal PMID:28671664 NCBI chr 4:102,236,868...102,311,359
Ensembl chr 4:112,804,645...112,865,581
JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (MGI:1330710|PMID:9892684) MGI PMID:9892684 MGI:1330710 NCBI chr 1:182,923,369...182,962,518
Ensembl chr 1:187,201,081...187,240,350
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15230
    immune system process 2261
      activation of immune response 278
        complement activation 48
          regulation of complement activation 27
            negative regulation of complement activation + 12
            positive regulation of complement activation + 7
            regulation of activation of membrane attack complex + 4
            regulation of complement activation, alternative pathway + 7
            regulation of complement activation, classical pathway + 7
            regulation of complement activation, lectin pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 15230
    biological regulation 10799
      regulation of biological process 10214
        regulation of response to stimulus 3677
          positive regulation of response to stimulus 2093
            positive regulation of immune response 493
              activation of immune response 278
                complement activation 48
                  regulation of complement activation 27
                    negative regulation of complement activation + 12
                    positive regulation of complement activation + 7
                    regulation of activation of membrane attack complex + 4
                    regulation of complement activation, alternative pathway + 7
                    regulation of complement activation, classical pathway + 7
                    regulation of complement activation, lectin pathway + 2
paths to the root