Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of complement activation
go back to main search page
Accession:GO:0030449 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of complement activation.
Synonyms:exact_synonym: regulation of complement cascade



show annotations for term's descendants           Sort by:
 
regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:8195709)
UniProt
RGD
PMID:8195709 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C3 complement C3 involved_in ISO (PMID:6225800) RGD PMID:6225800 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) RGD PMID:25284781 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cd59 CD59 molecule acts_upstream_of_or_within NAS
ISO
(PMID:25284781) RGD PMID:25284781 PMID:7528012 RGD:727654 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cd5l Cd5 molecule-like acts_upstream_of_or_within ISO MGI:2653296 (MGI:5617896|PMID:25284781) RGD PMID:25284781 MGI:5617896 NCBI chr 2:172,791,007...172,802,018 JBrowse link
G Cfh complement factor H acts_upstream_of_or_within IDA
ISO
(PMID:25284781)
MGI:2384179 (MGI:3833206|PMID:18947875)
RGD PMID:18947875 PMID:25284781 PMID:12374811 MGI:3833206, RGD:628500 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO MGI:2158683 (MGI:3833206|PMID:18947875)
(PMID:25284781)
RGD PMID:18947875 PMID:25284781 MGI:3833206 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Phb2 prohibitin 2 NOT|involved_in ISO (PMID:17070910) RGD PMID:17070910 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272
JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) RGD PMID:23482636 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59 CD59 molecule acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(MGI:1888643|PMID:10946279), (MGI:2148385|PMID:11471050)
PMID:21873635
RGD PMID:10946279 PMID:11471050 PMID:15843577 PMID:21873635 MGI:1888643 MGI:2148385, RGD:1600482, RGD:13792537 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in IDA
ISO
(PMID:28657829), (PMID:6211481) RGD PMID:6211481 PMID:28657829 PMID:10929073 RGD:2326180 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cd59 CD59 molecule acts_upstream_of_or_within ISO (MGI:1888643|PMID:10946279) RGD PMID:10946279 MGI:1888643 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within IMP
ISO
MGI:2158683 (MGI:1351571|PMID:10642554) RGD PMID:10642554 PMID:11861390 MGI:1351571, RGD:625470 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) RGD PMID:11485744 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) RGD PMID:9029106 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO
IBA
(PMID:23482636)
PMID:21873635
RGD PMID:23482636 PMID:21873635 RGD:13792537 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in IBA
ISO
PMID:21873635
UniProtKB:P01024 (PMID:17051150)
RGD PMID:17051150 PMID:21873635 RGD:13792537 NCBI chr  X:61,144,926...61,170,212
Ensembl chr  X:61,144,928...61,170,212
JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in ISO
IBA
IEA
(PMID:22333221)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:22333221 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA
(PMID:22333221)
GO_REF:0000107
RGD
Ensembl
PMID:22333221 GO_REF:0000107 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
JBrowse link
G Cd46 CD46 molecule involved_in ISO
IBA
(PMID:9029106)
PMID:21873635
RGD PMID:9029106 PMID:21873635 RGD:13792537 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Cr2 complement C3d receptor 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:106,678,579...106,716,595
Ensembl chr13:106,685,413...106,716,235
JBrowse link
G RGD1559810 similar to hypothetical protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:33,996,404...33,997,405
Ensembl chr20:33,996,224...33,997,432
JBrowse link
G Susd4 sushi domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:23482636)
RGD PMID:23482636 PMID:21873635 RGD:13792537 NCBI chr13:94,455,180...94,577,773
Ensembl chr13:94,455,165...94,577,750
JBrowse link
G Zp3r zona pellucida 3 receptor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:42,019,998...42,064,836
Ensembl chr13:42,020,018...42,064,812
JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin involved_in ISO (PMID:12538697) RGD PMID:12538697 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Serping1 serpin family G member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:10946292)
UniProt
RGD
PMID:10946292 GO_REF:0000024 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISO
GO_REF:0000107
(MGI:4430818|PMID:15611275)
Ensembl
RGD
PMID:15611275 GO_REF:0000107 MGI:4430818 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) RGD PMID:15611275 MGI:4430818 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C6 complement C6 involved_in ISO (MGI:4430818|PMID:15611275) RGD PMID:15611275 MGI:4430818 NCBI chr 2:53,846,027...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA
RNAcentral:URS0000424278_9606 (PMID:29384235)
GO_REF:0000107
RGD
Ensembl
PMID:29384235 GO_REF:0000107 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mbl2 mannose binding lectin 2 IDA RGD PMID:9920905 RGD:4889148 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:17070910) RGD PMID:17070910 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (MGI:6275756|PMID:30548312) RGD PMID:30548312 MGI:6275756 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
JBrowse link
regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in ISO (PMID:28671664) RGD PMID:28671664 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cfh complement factor H involved_in ISO (PMID:20378178), (PMID:28671664) RGD PMID:20378178 PMID:28671664 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cfi complement factor I involved_in ISO (PMID:28671664) RGD PMID:28671664 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
JBrowse link
regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO MGI:2387405 (MGI:1330710|PMID:9892684) RGD PMID:9892684 MGI:1330710 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    immune system process 2829
      activation of immune response 405
        complement activation 164
          regulation of complement activation 25
            negative regulation of complement activation + 14
            positive regulation of complement activation + 6
            regulation of activation of membrane attack complex + 3
            regulation of complement activation, alternative pathway + 6
            regulation of complement activation, classical pathway + 10
            regulation of complement activation, lectin pathway + 2
Path 2
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological process 12866
        regulation of response to stimulus 4054
          positive regulation of response to stimulus 2354
            positive regulation of immune response 632
              activation of immune response 405
                complement activation 164
                  regulation of complement activation 25
                    negative regulation of complement activation + 14
                    positive regulation of complement activation + 6
                    regulation of activation of membrane attack complex + 3
                    regulation of complement activation, alternative pathway + 6
                    regulation of complement activation, classical pathway + 10
                    regulation of complement activation, lectin pathway + 2
paths to the root