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ONTOLOGY REPORT - ANNOTATIONS

Term:sleep
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Accession:GO:0030431 term browser browse the term
Definition:Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
Synonyms:related_synonym: diapause;   dormancy;   lethargus
 xref: Wikipedia:Sleep

show annotations for term's descendants           Sort by:
 
sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1I calcium voltage-gated channel subunit alpha1 I IEA Ensembl GO_REF:0000107 NCBI chr22:39,570,753...39,689,737
Ensembl chr22:39,570,753...39,689,735 		JBrowse link
G DLAT dihydrolipoamide S-acetyltransferase IEA Ensembl GO_REF:0000107 NCBI chr11:112,025,408...112,064,404
Ensembl chr11:112,024,814...112,064,390
Ensembl chr11:112,024,814...112,064,390 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit IEA Ensembl GO_REF:0000107 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO RGD PMID:16690212 RGD:2293769 NCBI chr 2:28,392,855...28,417,317
Ensembl chr 2:28,392,448...28,417,317 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A IEA Ensembl GO_REF:0000107 NCBI chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928
Ensembl chr16:9,753,404...10,182,928 		JBrowse link
G HCRT hypocretin neuropeptide precursor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:42,184,060...42,185,452
Ensembl chr17:42,184,060...42,185,452 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A IEA Ensembl GO_REF:0000107 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,550...46,897,076
Ensembl chr13:46,831,550...46,897,076 		JBrowse link
G IL18 interleukin 18 ISS (PMID:11506998) UniProtKB PMID:11506998 NCBI chr11:112,143,251...112,164,104
Ensembl chr11:112,143,253...112,164,096 		JBrowse link
G MRGPRX2 MAS related GPR family member X2 NAS (PMID:12915402) UniProtKB PMID:12915402 NCBI chr11:19,054,455...19,060,717
Ensembl chr11:19,054,455...19,060,717 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide IEA Ensembl GO_REF:0000107 NCBI chr20:3,068,871...3,072,517
Ensembl chr20:3,071,620...3,072,517 		JBrowse link
G OXTR oxytocin receptor IEA Ensembl GO_REF:0000107 NCBI chr 3:8,750,381...8,769,613
Ensembl chr 3:8,750,408...8,769,628 		JBrowse link
G PTGDR prostaglandin D2 receptor ISO (MGI:3761771|PMID:11562489) MGI PMID:11562489 MGI:3761771 NCBI chr14:52,267,256...52,276,724
Ensembl chr14:52,267,698...52,276,724 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) IEA Ensembl GO_REF:0000107 NCBI chr 6:44,219,587...44,234,144
Ensembl chr 6:44,219,553...44,234,142
Ensembl chr 6:44,219,553...44,234,142 		JBrowse link
G SNAP25 synaptosome associated protein 25 ISO RGD PMID:16273548 RGD:1581074 NCBI chr20:10,218,830...10,307,420
Ensembl chr20:10,218,830...10,307,418 		JBrowse link
circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTBD9 BTB domain containing 9 IEA Ensembl GO_REF:0000107 NCBI chr 6:38,168,451...38,640,541
Ensembl chr 6:38,168,451...38,640,148 		JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:17537840 RGD:2289986 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,082...37,261,835 		JBrowse link
circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C ISO RGD PMID:17027151 RGD:2306498 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 ISO (MGI:2445919|PMID:12419540) MGI PMID:12419540 MGI:2445919 NCBI chr15:26,543,552...26,773,763
Ensembl chr15:26,543,546...26,939,539 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:20844122 RGD:13515123 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:6,633,440...6,674,386
Ensembl chr 5:6,633,427...6,674,386 		JBrowse link
G STAR steroidogenic acute regulatory protein IEA Ensembl GO_REF:0000107 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,619,522...44,652,233 		JBrowse link
G ADORA1 adenosine A1 receptor IEA Ensembl GO_REF:0000107 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone NAS (PMID:18329818) BHF-UCL PMID:18329818 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide IDA (PMID:18329818) BHF-UCL PMID:18329818 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:18466985 RGD:6480669 NCBI chr10:90,738,693...90,858,039
Ensembl chr10:90,740,823...90,858,039 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 5:40,679,915...40,740,936
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr 1:203,127,705...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12944496 RGD:1581422 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 IEA Ensembl GO_REF:0000107 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin ISO RGD PMID:9748091 RGD:1625449 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G CASP1 caspase 1 ISO RGD PMID:16455762 RGD:2315921 NCBI chr11:105,025,443...105,035,591
Ensembl chr11:105,025,443...105,035,250 		JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:19889861 PMID:20237285 RGD:10401262 RGD:2325188 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,082...37,261,835 		JBrowse link
G GHRHR growth hormone releasing hormone receptor IEA Ensembl GO_REF:0000107 NCBI chr 7:30,963,953...30,979,528
Ensembl chr 7:30,938,669...30,993,254 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide IDA (PMID:18329818) BHF-UCL PMID:18329818 NCBI chr 3:10,285,666...10,292,947
Ensembl chr 3:10,285,666...10,292,947 		JBrowse link
G MTNR1B melatonin receptor 1B IEA Ensembl GO_REF:0000107 NCBI chr11:92,969,651...92,986,241
Ensembl chr11:92,969,651...92,985,066
Ensembl chr11:92,969,651...92,985,066 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 IEA Ensembl GO_REF:0000107 NCBI chr 4:155,173,723...155,217,076
Ensembl chr 4:155,208,636...155,217,078 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,808 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 5:40,679,915...40,740,936
Ensembl chr 5:40,679,915...40,693,735 		JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRH growth hormone releasing hormone NOT IMP
NAS		 (PMID:15538933)
(PMID:18329818)		 BHF-UCL PMID:15538933 PMID:18329818 NCBI chr20:37,251,086...37,261,814
Ensembl chr20:37,251,082...37,261,835 		JBrowse link
G PMCH pro-melanin concentrating hormone ISO RGD PMID:12964948 RGD:1642489 NCBI chr12:102,196,459...102,199,540
Ensembl chr12:102,196,459...102,197,833 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 1:7,846,345...7,913,615
Ensembl chr 1:7,843,083...7,853,512 		JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844 NCBI chr17:82,371,765...82,377,458
Ensembl chr17:82,371,400...82,375,586
Ensembl chr17:82,371,400...82,375,586 		JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor IEA Ensembl GO_REF:0000107 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G OPN4 opsin 4 ISO (MGI:5925970|PMID:26320947) MGI PMID:26320947 MGI:5925970 NCBI chr10:86,653,495...86,666,460
Ensembl chr10:86,654,547...86,666,848 		JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:12667648 RGD:1358315 NCBI chr 7:22,725,889...22,732,002
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 ISO (MGI:3770734|PMID:17925011) UniProt PMID:17925011 MGI:3770734 NCBI chr 1:110,593,580...110,631,536
Ensembl chr 1:110,519,837...110,631,474 		JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISS UniProtKB GO_REF:0000024 NCBI chr 1:154,567,778...154,584,708
Ensembl chr 1:154,567,778...154,580,013 		JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:11038259 RGD:631747 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,619,522...44,652,233 		JBrowse link
G ADRB1 adrenoceptor beta 1 IMP (PMID:25083013) UniProt PMID:25083013 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G CORT cortistatin ISO RGD PMID:8622767 RGD:727760 NCBI chr 1:10,450,031...10,451,998
Ensembl chr 1:10,449,719...10,451,902
Ensembl chr 1:10,449,719...10,451,902 		JBrowse link
G CSF2 colony stimulating factor 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170 		JBrowse link
G DRD3 dopamine receptor D3 IEA Ensembl GO_REF:0000107 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G NMU neuromedin U IEA Ensembl GO_REF:0000107 NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698 		JBrowse link
G PER3 period circadian regulator 3 IMP (PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630) UniProtKB PMID:17346965 PMID:19716732 PMID:24439663 PMID:24577121 PMID:26903630 NCBI chr 1:7,784,285...7,845,181
Ensembl chr 1:7,784,320...7,845,177 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 ISO RGD PMID:11145837 RGD:724610 NCBI chr19:46,019,153...46,023,053
Ensembl chr19:46,019,153...46,023,053 		JBrowse link
G PTGDS prostaglandin D2 synthase ISS UniProtKB GO_REF:0000024 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18678
    multicellular organismal process 8790
      sleep 51
        circadian sleep/wake cycle, sleep + 37
        estivation 0
        hibernation + 0
paths to the root