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ONTOLOGY REPORT - ANNOTATIONS

Term:sleep
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Accession:GO:0030431 term browser browse the term
Definition:Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
Synonyms:related_synonym: diapause;   dormancy;   lethargus
 xref: Wikipedia:Sleep

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sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1I calcium voltage-gated channel subunit alpha1 I ISO (MGI:5286762|PMID:21808016) MGI PMID:21808016 MGI:5286762 NCBI chr22:20,463,511...20,595,253
Ensembl chr22:38,296,436...38,414,963 		JBrowse link
G DLAT dihydrolipoamide S-acetyltransferase ISO RGD PMID:16923172 RGD:2313667 NCBI chr11:106,910,857...106,950,851
Ensembl chr11:110,756,001...110,792,795 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:17274184 RGD:2293765 NCBI chr14:55,832,570...55,835,984
Ensembl chr14:74,676,316...74,679,766 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit ISO RGD PMID:16690212 RGD:2293769 NCBI chr2A:28,392,328...28,416,838
Ensembl chr2A:28,485,613...28,498,397 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO (MGI:3629276|PMID:12754515) MGI PMID:12754515 MGI:3629276 NCBI chr16:8,682,169...9,105,581
Ensembl chr16:9,919,143...10,336,167 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A ISO RGD PMID:17059817 RGD:1624384 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826 		JBrowse link
G IL18 interleukin 18 ISO PMID:11506998 UniProt PMID:11506998 RGD:8554500 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:12832103 RGD:2304184 NCBI chr20:3,157,246...3,159,013 JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:12832103 RGD:2304184 NCBI chr 3:8,701,344...8,721,706 JBrowse link
G PTGDR prostaglandin D2 receptor ISO (MGI:3761771|PMID:11562489) MGI PMID:11562489 MGI:3761771 NCBI chr14:32,863,852...32,873,492
Ensembl chr14:51,149,155...51,158,161 		JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) ISO RGD PMID:14633241 RGD:2316943 NCBI chr 6:43,815,006...43,830,290
Ensembl chr 6:45,099,243...45,113,689 		JBrowse link
G SNAP25 synaptosome associated protein 25 ISO RGD PMID:16273548 RGD:1581074 NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841 		JBrowse link
circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BTBD9 BTB domain containing 9 ISO (MGI:5436392|PMID:22678064) MGI PMID:22678064 MGI:5436392 NCBI chr 6:37,733,575...38,211,857
Ensembl chr 6:38,928,879...39,358,424 		JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:17537840 RGD:2289986 NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240 		JBrowse link
circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C ISO RGD PMID:17027151 RGD:2306498 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 ISO (MGI:2445919|PMID:12419540) MGI PMID:12419540 MGI:2445919 NCBI chr15:3,129,481...3,357,495
Ensembl chr15:23,981,359...24,058,357 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha ISO RGD PMID:20844122 RGD:13515123 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO deprivation RGD PMID:12597996 RGD:4891963 NCBI chr 5:6,953,795...6,996,010
Ensembl chr 5:6,629,093...6,664,264 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO deprivation RGD PMID:12597996 RGD:4891963 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:19066225 RGD:5128864 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:19491711 RGD:2317916 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO (PMID:18329818) BHF-UCL PMID:18329818 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G HTR7 5-hydroxytryptamine receptor 7 ISO RGD PMID:18466985 RGD:6480669 NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA1 adenosine A1 receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12944496 RGD:1581422 NCBI chr 5:170,787,115...170,792,383
Ensembl chr 5:177,688,917...177,690,257 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:12944496 RGD:1581422 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALB albumin ISO RGD PMID:9748091 RGD:1625449 NCBI chr 4:50,773,244...50,790,474
Ensembl chr 4:56,605,322...56,622,418 		JBrowse link
G CASP1 caspase 1 ISO RGD PMID:16455762 RGD:2315921 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G GHRH growth hormone releasing hormone ISO RGD PMID:19889861 PMID:20237285 RGD:10401262 RGD:2325188 NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240 		JBrowse link
G GHRHR growth hormone releasing hormone receptor ISO RGD PMID:20237285 RGD:10401262 NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO (PMID:18329818) BHF-UCL PMID:18329818 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:19429170 PMID:22171046 RGD:9588660 RGD:9588665 NCBI chr11:87,996,805...88,009,865
Ensembl chr11:91,491,822...91,504,652 		JBrowse link
G NPY2R neuropeptide Y receptor Y2 ISO RGD PMID:16378653 RGD:1642507 NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063 		JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148 		JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRH growth hormone releasing hormone NOT ISO (PMID:15538933) BHF-UCL PMID:15538933 NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240 		JBrowse link
G PMCH pro-melanin concentrating hormone ISO RGD PMID:12964948 RGD:1642489 NCBI chr12:99,783,925...99,785,292
Ensembl chr12:103,181,497...103,182,616 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688 		JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844 NCBI chr17:76,783,432...76,788,639
Ensembl chr17:82,592,312...82,593,702 		JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189 		JBrowse link
G OPN4 opsin 4 ISO (MGI:5925970|PMID:26320947) MGI PMID:26320947 MGI:5925970 NCBI chr10:83,082,351...83,095,161 JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:12667648 RGD:1358315 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 ISO (MGI:3770734|PMID:17925011) UniProt PMID:17925011 MGI:3770734 NCBI chr 1:113,187,158...113,256,260
Ensembl chr 1:127,090,829...127,092,328 		JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361 		JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase ISO RGD PMID:11038259 RGD:631747 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO (PMID:25083013)
(MGI:6368107|PMID:25083013)		 UniProt PMID:25083013 MGI:6368107 NCBI chr10:110,642,491...110,646,595 JBrowse link
G CORT cortistatin ISO RGD PMID:8622767 RGD:727760 NCBI chr 1:9,210,186...9,212,201 JBrowse link
G CSF2 colony stimulating factor 2 ISO RGD PMID:12047622 RGD:10449529 NCBI chr 5:127,496,951...127,499,325
Ensembl chr 5:133,660,775...133,663,146 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:15913875 RGD:1625069 NCBI chr 3:111,265,834...111,317,176
Ensembl chr 3:118,187,636...118,237,403 		JBrowse link
G NMU neuromedin U ISO PMID:20233222 UniProt PMID:20233222 RGD:12911001 NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965 		JBrowse link
G PER3 period circadian regulator 3 ISO (PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630)
(MGI:5300112|PMID:21957163)		 UniProtKB
UniProt		 PMID:17346965 PMID:19716732 PMID:21957163 PMID:24439663 PMID:24577121 PMID:26903630 MGI:5300112 NCBI chr 1:6,547,667...6,607,905
Ensembl chr 1:7,795,552...7,855,922 		JBrowse link
G PGLYRP1 peptidoglycan recognition protein 1 ISO RGD PMID:11145837 RGD:724610 NCBI chr19:43,033,080...43,037,726
Ensembl chr19:51,569,275...51,573,764 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO (MGI:3687807|PMID:10781097) UniProt PMID:10781097 MGI:3687807 NCBI chr 9:108,037,994...108,042,136 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12593
    multicellular organismal process 6479
      sleep 48
        circadian sleep/wake cycle, sleep + 36
        estivation 0
        hibernation + 0
paths to the root