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ONTOLOGY REPORT - ANNOTATIONS

Term:sleep
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Accession:GO:0030431 term browser browse the term
Definition:Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
Synonyms:related_synonym: diapause;   dormancy;   lethargus
 xref: Wikipedia:Sleep

show annotations for term's descendants           Sort by:
 
sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1i calcium voltage-gated channel subunit alpha1 I ISO (MGI:5286762|PMID:21808016) RGD PMID:21808016 MGI:5286762 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase IEP RGD PMID:16923172 RGD:2313667 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:17274184 RGD:2293765 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit IEP RGD PMID:16690212 RGD:2293769 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEA
ISO		 GO_REF:0000107
MGI:1928285 (MGI:3629276|PMID:12754515)		 Ensembl
RGD		 PMID:12754515 GO_REF:0000107, MGI:3629276 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990 		JBrowse link
G Hcrt hypocretin neuropeptide precursor IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17059817 RGD:1624384 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382 		JBrowse link
G Il18 interleukin 18 TAS
IDA		 PMID:11506998 RGD
UniProt		 PMID:12468024, PMID:11506998 RGD:727478, RGD:8554500 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:12832103 RGD:2304184 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:12832103 RGD:2304184 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116 		JBrowse link
G Ptgdr prostaglandin D2 receptor ISO MGI:2386956 (MGI:3761771|PMID:11562489) RGD PMID:11562489 MGI:3761771 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Slc29a1 solute carrier family 29 member 1 IMP RGD PMID:14633241 RGD:2316943 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005 		JBrowse link
G Snap25 synaptosome associated protein 25 IDA RGD PMID:16273548 RGD:1581074 NCBI chr 3:129,697,408...129,788,417
Ensembl chr 3:129,599,353...129,788,400 		JBrowse link
circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd9 BTB domain containing 9 ISO MGI:4127237 (MGI:5436392|PMID:22678064) RGD PMID:22678064 MGI:5436392 NCBI chr20:8,899,286...9,253,936
Ensembl chr20:8,901,931...9,249,820 		JBrowse link
G Ghrh growth hormone releasing hormone IDA RGD PMID:17537840 RGD:2289986 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794 		JBrowse link
circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C IEP RGD PMID:17027151 RGD:2306498 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 ISO (MGI:2445919|PMID:12419540) RGD PMID:12419540 MGI:2445919 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEP RGD PMID:20844122 RGD:13515123 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP deprivation RGD PMID:12597996 RGD:4891963 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756 		JBrowse link
G Star steroidogenic acute regulatory protein IEP deprivation RGD PMID:12597996 RGD:4891963 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:19066225 RGD:5128864 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19491711 RGD:2317916 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA RGD PMID:18466985 RGD:6480669 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:12944496 RGD:1581422 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12944496 RGD:1581422 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin IDA RGD PMID:9748091 RGD:1625449 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Casp1 caspase 1 IMP RGD PMID:16455762 RGD:2315921 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631 		JBrowse link
G Ghrh growth hormone releasing hormone IMP RGD PMID:19889861, PMID:20237285 RGD:2325188, RGD:10401262 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor IMP RGD PMID:20237285 RGD:10401262 NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Mtnr1b melatonin receptor 1B IDA
IMP		 RGD PMID:19429170, PMID:22171046 RGD:9588660, RGD:9588665 NCBI chr 8:14,359,270...14,373,894
Ensembl chr 8:14,359,270...14,373,894 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:16378653 RGD:1642507 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448 		JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrh growth hormone releasing hormone NOT ISO (PMID:15538933) RGD PMID:15538933 NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794 		JBrowse link
G Pmch pro-melanin-concentrating hormone IDA RGD PMID:12964948 RGD:1642489 NCBI chr 7:28,655,206...28,656,522
Ensembl chr 7:28,654,733...28,657,522 		JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:15944374 RGD:2306844 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145 		JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:15944374 RGD:2306844 NCBI chr10:110,364,291...110,365,451
Ensembl chr10:110,364,291...110,365,451 		JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G Opn4 opsin 4 ISO (MGI:5925970|PMID:26320947) RGD PMID:26320947 MGI:5925970 NCBI chr16:10,943,353...10,966,602
Ensembl chr16:10,943,341...10,952,549 		JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:1926253 (MGI:3575072|PMID:15215293) RGD PMID:15215293 MGI:3575072 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Il18 interleukin 18 TAS PMID:11506998 UniProt PMID:11506998 RGD:8554500 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299 		JBrowse link
G Il6 interleukin 6 IMP RGD PMID:12667648 RGD:1358315 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 ISO (MGI:3770734|PMID:17925011) RGD PMID:17925011 MGI:3770734 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471 		JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO MGI:1926253 (MGI:3575072|PMID:15215293) RGD PMID:15215293 MGI:3575072 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IEP RGD PMID:11038259 RGD:631747 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947 		JBrowse link
G Adrb1 adrenoceptor beta 1 ISO
IEA
ISS		 (PMID:25083013)
(MGI:6368107|PMID:25083013)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:25083013 GO_REF:0000024, GO_REF:0000107, MGI:6368107 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985 		JBrowse link
G Cort cortistatin IDA RGD PMID:8622767 RGD:727760 NCBI chr 5:165,942,780...165,944,221 JBrowse link
G Csf2 colony stimulating factor 2 IMP RGD PMID:12047622 RGD:10449529 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Drd3 dopamine receptor D3 IMP RGD PMID:15913875 RGD:1625069 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327 		JBrowse link
G Nmu neuromedin U IDA PMID:20233222 UniProt PMID:20233222 RGD:12911001 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828 		JBrowse link
G Per3 period circadian regulator 3 IEA
ISO
ISS		 GO_REF:0000107
(MGI:5300112|PMID:21957163)
(PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17346965, PMID:19716732, PMID:21957163, PMID:24439663, PMID:24577121, PMID:26903630 GO_REF:0000024, GO_REF:0000107, MGI:5300112 NCBI chr 5:168,088,126...168,123,482
Ensembl chr 5:168,086,998...168,123,395 		JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IEP RGD PMID:11145837 RGD:724610 NCBI chr 1:79,790,879...79,796,064
Ensembl chr 1:79,790,705...79,796,111 		JBrowse link
G Ptgds prostaglandin D2 synthase ISS
ISO		 PMID:10781097
(MGI:3687807|PMID:10781097)		 RGD PMID:10781097, PMID:10781097 MGI:3687807, RGD:8553735 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    multicellular organismal process 9047
      sleep 49
        circadian sleep/wake cycle, sleep + 37
        estivation 0
        hibernation + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.