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ONTOLOGY REPORT - ANNOTATIONS

Term:sleep
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Accession:GO:0030431 term browser browse the term
Definition:Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
Synonyms:related_synonym: diapause;   dormancy;   lethargus
 xref: Wikipedia:Sleep


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sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1i calcium voltage-gated channel subunit alpha1 I acts_upstream_of_or_within ISO (MGI:5286762|PMID:21808016) RGD PMID:21808016 MGI:5286762 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase IEP RGD PMID:16923172 RGD:2313667 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:17274184 RGD:2293765 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit IEP RGD PMID:16690212 RGD:2293769 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1928285 (MGI:3629276|PMID:12754515)		 Ensembl
RGD		 PMID:12754515 GO_REF:0000107 MGI:3629276 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Hcrt hypocretin neuropeptide precursor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17059817 RGD:1624384 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Il18 interleukin 18 involved_in TAS
IDA		 PMID:11506998 RGD
UniProt		 PMID:12468024 PMID:11506998 RGD:727478, RGD:8554500 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:12832103 RGD:2304184 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:12832103 RGD:2304184 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Ptgdr prostaglandin D2 receptor acts_upstream_of_or_within ISO MGI:2386956 (MGI:3761771|PMID:11562489) RGD PMID:11562489 MGI:3761771 NCBI chr15:17,360,304...17,367,679 JBrowse link
G Slc29a1 solute carrier family 29 member 1 IMP RGD PMID:14633241 RGD:2316943 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Snap25 synaptosome associated protein 25 IDA RGD PMID:16273548 RGD:1581074 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd9 BTB domain containing 9 acts_upstream_of_or_within ISO MGI:4127237 (MGI:5436392|PMID:22678064) RGD PMID:22678064 MGI:5436392 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Ghrh growth hormone releasing hormone IDA RGD PMID:17537840 RGD:2289986 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C IEP RGD PMID:17027151 RGD:2306498 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 acts_upstream_of_or_within ISO (MGI:2445919|PMID:12419540) RGD PMID:12419540 MGI:2445919 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEP RGD PMID:20844122 RGD:13515123 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP deprivation RGD PMID:12597996 RGD:4891963 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Star steroidogenic acute regulatory protein IEP deprivation RGD PMID:12597996 RGD:4891963 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:19066225 RGD:5128864 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19491711 RGD:2317916 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA RGD PMID:18466985 RGD:6480669 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:12944496 RGD:1581422 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12944496 RGD:1581422 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin IDA RGD PMID:9748091 RGD:1625449 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Casp1 caspase 1 IMP RGD PMID:16455762 RGD:2315921 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ghrh growth hormone releasing hormone IMP RGD PMID:19889861 PMID:20237285 RGD:2325188, RGD:10401262 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor IMP RGD PMID:20237285 RGD:10401262 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Mtnr1b melatonin receptor 1B IDA
IMP		 RGD PMID:19429170 PMID:22171046 RGD:9588660, RGD:9588665 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:16378653 RGD:1642507 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrh growth hormone releasing hormone NOT|involved_in ISO (PMID:15538933) RGD PMID:15538933 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Pmch pro-melanin-concentrating hormone IDA RGD PMID:12964948 RGD:1642489 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250 		JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:15944374 RGD:2306844 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237 		JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:15944374 RGD:2306844 NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252 		JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Opn4 opsin 4 acts_upstream_of_or_within ISO (MGI:5925970|PMID:26320947) RGD PMID:26320947 MGI:5925970 NCBI chr16:9,920,408...9,929,580
Ensembl chr16:9,920,491...10,005,711 		JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3575072|PMID:15215293) RGD PMID:15215293 MGI:3575072 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Il18 interleukin 18 involved_in TAS PMID:11506998 UniProt PMID:11506998 RGD:8554500 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 IMP RGD PMID:12667648 RGD:1358315 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 involved_in ISO (MGI:3770734|PMID:17925011) RGD PMID:17925011 MGI:3770734 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3575072|PMID:15215293) RGD PMID:15215293 MGI:3575072 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IEP RGD PMID:11038259 RGD:631747 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6368107|PMID:25083013)
GO_REF:0000107
(PMID:25083013)		 UniProt
RGD
Ensembl		 PMID:25083013 GO_REF:0000024 GO_REF:0000107 MGI:6368107 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Cort cortistatin IDA RGD PMID:8622767 RGD:727760 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Csf2 colony stimulating factor 2 IMP RGD PMID:12047622 RGD:10449529 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Drd3 dopamine receptor D3 IMP RGD PMID:15913875 RGD:1625069 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:20233222 UniProt PMID:20233222 RGD:12911001 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Per3 period circadian regulator 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5300112|PMID:21957163)
(PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630)		 UniProt
Ensembl
RGD		 PMID:17346965 PMID:19716732 PMID:21957163 PMID:24439663 PMID:24577121 More... GO_REF:0000024 GO_REF:0000107 MGI:5300112 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IEP RGD PMID:11145837 RGD:724610 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001 		JBrowse link
G Ptgds prostaglandin D2 synthase involved_in ISS
ISO		 PMID:10781097
(MGI:3687807|PMID:10781097)		 RGD PMID:10781097 PMID:10781097 MGI:3687807, RGD:8553735 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19391
    multicellular organismal process 8819
      sleep 49
        circadian sleep/wake cycle, sleep + 37
paths to the root