Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:sleep
go back to main search page
Accession:GO:0030431 term browser browse the term
Definition:Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
Synonyms:related_synonym: diapause;   dormancy;   lethargus
 xref: Wikipedia:Sleep


show annotations for term's descendants           Sort by:
sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1i calcium voltage-gated channel subunit alpha1 I acts_upstream_of_or_within ISO (MGI:5286762|PMID:21808016) RGD PMID:21808016 MGI:5286762 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase IEP RGD PMID:16923172 RGD:2313667 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP RGD PMID:17274184 RGD:2293765 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit IEP RGD PMID:16690212 RGD:2293769 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1928285 (MGI:3629276|PMID:12754515)		 Ensembl
RGD		 PMID:12754515 GO_REF:0000107 MGI:3629276 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Hcrt hypocretin neuropeptide precursor involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:85,689,992...85,691,206
Ensembl chr10:85,689,465...85,691,210 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17059817 RGD:1624384 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Il18 interleukin 18 involved_in TAS
IDA		 PMID:11506998 RGD
UniProt		 PMID:12468024 PMID:11506998 RGD:727478, RGD:8554500 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:12832103 RGD:2304184 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:12832103 RGD:2304184 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Ptgdr prostaglandin D2 receptor acts_upstream_of_or_within ISO MGI:2386956 (MGI:3761771|PMID:11562489) RGD PMID:11562489 MGI:3761771 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 IMP RGD PMID:14633241 RGD:2316943 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Snap25 synaptosome associated protein 25 IDA RGD PMID:16273548 RGD:1581074 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btbd9 BTB domain containing 9 acts_upstream_of_or_within ISO MGI:4127237 (MGI:5436392|PMID:22678064) RGD PMID:22678064 MGI:5436392 NCBI chr20:8,286,337...8,645,567
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Ghrh growth hormone releasing hormone IDA RGD PMID:17537840 RGD:2289986 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C IEP RGD PMID:17027151 RGD:2306498 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 acts_upstream_of_or_within ISO (MGI:2445919|PMID:12419540) RGD PMID:12419540 MGI:2445919 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEP RGD PMID:20844122 RGD:13515123 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP deprivation RGD PMID:12597996 RGD:4891963 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Star steroidogenic acute regulatory protein IEP deprivation RGD PMID:12597996 RGD:4891963 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:19066225 RGD:5128864 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19491711 RGD:2317916 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA RGD PMID:18466985 RGD:6480669 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:12944496 RGD:1581422 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12944496 RGD:1581422 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin IDA RGD PMID:9748091 RGD:1625449 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Casp1 caspase 1 IMP RGD PMID:16455762 RGD:2315921 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ghrh growth hormone releasing hormone IMP RGD PMID:19889861 PMID:20237285 RGD:2325188, RGD:10401262 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor IMP RGD PMID:20237285 RGD:10401262 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide involved_in ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Mtnr1b melatonin receptor 1B IDA
IMP		 RGD PMID:19429170 PMID:22171046 RGD:9588660, RGD:9588665 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:16378653 RGD:1642507 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrh growth hormone releasing hormone NOT|involved_in ISO (PMID:15538933) RGD PMID:15538933 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Pmch pro-melanin-concentrating hormone IDA RGD PMID:12964948 RGD:1642489 NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250 		JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:15944374 RGD:2306844 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237 		JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:15944374 RGD:2306844 NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252 		JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Opn4 opsin 4 acts_upstream_of_or_within ISO (MGI:5925970|PMID:26320947) RGD PMID:26320947 MGI:5925970 NCBI chr16:9,920,408...9,929,580
Ensembl chr16:9,920,491...10,005,711 		JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3575072|PMID:15215293) RGD PMID:15215293 MGI:3575072 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Il18 interleukin 18 involved_in TAS PMID:11506998 UniProt PMID:11506998 RGD:8554500 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 IMP RGD PMID:12667648 RGD:1358315 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 involved_in ISO (MGI:3770734|PMID:17925011) RGD PMID:17925011 MGI:3770734 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6874638|PMID:34798058)		 UniProt
RGD		 PMID:34798058 GO_REF:0000024 MGI:6874638 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (MGI:3575072|PMID:15215293) RGD PMID:15215293 MGI:3575072 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IEP RGD PMID:11038259 RGD:631747 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adrb1 adrenoceptor beta 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:6368107|PMID:25083013)
GO_REF:0000107
(PMID:25083013)		 UniProt
RGD
Ensembl		 PMID:25083013 GO_REF:0000024 GO_REF:0000107 MGI:6368107 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Cort cortistatin IDA RGD PMID:8622767 RGD:727760 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Csf2 colony stimulating factor 2 IMP RGD PMID:12047622 RGD:10449529 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Drd3 dopamine receptor D3 IMP RGD PMID:15913875 RGD:1625069 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:20233222 UniProt PMID:20233222 RGD:12911001 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Per3 period circadian regulator 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5300112|PMID:21957163)
(PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630)		 UniProt
RGD		 PMID:17346965 PMID:19716732 PMID:21957163 PMID:24439663 PMID:24577121 More... GO_REF:0000024 MGI:5300112 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 IEP RGD PMID:11145837 RGD:724610 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001 		JBrowse link
G Ptgds prostaglandin D2 synthase involved_in ISS
ISO		 PMID:10781097
(MGI:3687807|PMID:10781097)		 RGD PMID:10781097 PMID:10781097 MGI:3687807, RGD:8553735 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    multicellular organismal process 9260
      sleep 50
        circadian sleep/wake cycle, sleep + 38
paths to the root