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ONTOLOGY REPORT - ANNOTATIONS


Term:cyclin binding
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Accession:GO:0030332 term browser browse the term
Definition:Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.


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cyclin binding term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:2301349
RGD:1624291
G Cdk12 cyclin-dependent kinase 12 JBrowse link 10 86,157,186 86,210,657 RGD:1624291
RGD:13792537
RGD:8553775
G Cdk13 cyclin-dependent kinase 13 JBrowse link 17 49,833,194 49,922,932 RGD:1624291
RGD:13792537
G Cdk14 cyclin-dependent kinase 14 JBrowse link 4 25,825,567 26,419,443 RGD:1624291
RGD:13792537
G Cdk15 cyclin-dependent kinase 15 JBrowse link 9 66,059,765 66,153,729 RGD:13792537
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:1582338
RGD:1624291
RGD:1600115
RGD:13792537
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:1582338
RGD:1624291
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link 10 84,780,644 84,789,800 RGD:1600115
RGD:1624291
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:1582338
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
G Ciz1 CDKN1A interacting zinc finger protein 1 JBrowse link 3 11,392,046 11,409,218 RGD:1624291
G Crabp2 cellular retinoic acid binding protein 2 JBrowse link 2 187,322,416 187,326,794 RGD:1624291
G Cul3 cullin 3 JBrowse link 9 86,044,485 86,129,066 RGD:1624291
RGD:1600115
G Fbxo31 F-box protein 31 JBrowse link 19 53,487,610 53,625,673 RGD:1600115
RGD:1624291
G Fbxw7 F-box and WD repeat domain containing 7 JBrowse link 2 184,230,191 184,309,805 RGD:1624291
G Gak cyclin G associated kinase JBrowse link 14 2,100,104 2,174,332 RGD:728630
G Gps2 G protein pathway suppressor 2 JBrowse link 10 56,524,327 56,527,447 RGD:1624291
G Hdac3 histone deacetylase 3 JBrowse link 18 31,073,057 31,094,347 RGD:1600115
RGD:1624291
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 JBrowse link 10 57,309,722 57,322,140 RGD:1624291
RGD:13792537
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
G Klhdc9 kelch domain containing 9 JBrowse link 13 89,742,750 89,746,254 RGD:1624291
RGD:13792537
G Mdfic MyoD family inhibitor domain containing JBrowse link 4 42,202,546 42,282,499 RGD:1624291
G Poln DNA polymerase nu JBrowse link 14 81,837,764 82,037,999 RGD:1624291
G Proca1 protein interacting with cyclin A1 JBrowse link 10 65,454,451 65,469,491 RGD:1624291
G Ptch1 patched 1 JBrowse link 17 1,032,242 1,085,885 RGD:1624291
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1624291
G Rbm4 RNA binding motif protein 4 JBrowse link 1 220,038,403 220,049,756 RGD:1624291
G Ube3d ubiquitin protein ligase E3D JBrowse link 8 93,948,689 94,120,477 RGD:1624291
RGD:13792537
G Usp2 ubiquitin specific peptidase 2 JBrowse link 8 48,403,985 48,432,525 RGD:1624291
G Xrcc6 X-ray repair cross complementing 6 JBrowse link 7 123,259,881 123,280,613 RGD:1624291

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Term Annotations click to browse term
  molecular_function 20377
    binding 16798
      protein binding 14233
        cyclin binding 31
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.