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ONTOLOGY REPORT - ANNOTATIONS


Term:T-tubule
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Accession:GO:0030315 term browser browse the term
Definition:Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
Synonyms:exact_synonym: transverse tubule
 related_synonym: triad
 xref: Wikipedia:T-tubule



show annotations for term's descendants           Sort by:
 
T-tubule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 IDA RGD PMID:15647111 RGD:1598637 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abcc9_v2 ATP binding cassette subfamily C member 9, variant 2 IDA RGD PMID:12738227 RGD:1598649
G Adra1a adrenoceptor alpha 1A IDA RGD PMID:18467629 RGD:5688343 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
JBrowse link
G Adra1b adrenoceptor alpha 1B IDA RGD PMID:18467629 RGD:5688343 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Akap6 A-kinase anchoring protein 6 located_in IDA PMID:9679148 BHF-UCL PMID:9679148 RGD:8553491 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Akap7 A-kinase anchoring protein 7 IDA RGD PMID:14569017 RGD:1304018 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
JBrowse link
G Ank2 ankyrin 2 located_in ISO (MGI:2449848|PMID:12571597), (MGI:3610760|PMID:16292983) RGD PMID:12571597 PMID:16292983 MGI:2449848 MGI:3610760 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ank3 ankyrin 3 located_in IDA PMID:15579534 BHF-UCL PMID:15579534 RGD:6484228 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Aqp4 aquaporin 4 IDA RGD PMID:20849844 RGD:5490121 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Asb15 ankyrin repeat and SOCS box containing 15 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:53,021,553...53,050,846
Ensembl chr 4:53,031,692...53,049,928
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 located_in ISO
IDA
UniProtKB:P05026 (PMID:19751721)
(MGI:3610760|PMID:16292983)
PMID:17442282
RGD PMID:16292983 PMID:19751721 PMID:17442282 MGI:3610760, RGD:6903343 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 located_in IDA
ISO
(MGI:3610760|PMID:16292983)
PMID:17442282
UniProtKB:P05026 (PMID:19751721)
RGD PMID:16292983 PMID:19751721 PMID:17442282 PMID:17442282 MGI:3610760, RGD:6903343, RGD:6903343 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 located_in ISO UniProtKB:P05023|UniProtKB:P50993 (PMID:19751721) RGD PMID:19751721 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 located_in ISO (PMID:19287093)
(MGI:3848765|PMID:19287093)
RGD PMID:19287093 MGI:3848765 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Bin1 bridging integrator 1 located_in IDA
ISO
IEA
PMID:9182667
(MGI:5583915|PMID:24836577)
GO_REF:0000107
RGD
Ensembl
PMID:24836577 PMID:9182667 GO_REF:0000107 MGI:5583915, RGD:8553847 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C located_in IDA
IEA
ISO
TAS
GO_REF:0000044
(MGI:5314827|PMID:22355118)
PMID:11053140
UniProt
RGD
PMID:22355118 PMID:14569017 PMID:11053140 GO_REF:0000044 MGI:5314827, RGD:1304018, RGD:8554533 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S located_in ISS
ISO
IEA
GO_REF:0000024
(MGI:1342891|PMID:10444070), (MGI:3529615|PMID:15536090), (MGI:84458|PMID:8943043)
(PMID:17204937)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8943043 PMID:10444070 PMID:15536090 PMID:17204937 GO_REF:0000024 GO_REF:0000107 MGI:1342891 MGI:3529615 MGI:84458 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 located_in ISO (MGI:3529615|PMID:15536090) RGD PMID:15536090 MGI:3529615 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 located_in ISO (MGI:84458|PMID:8943043) RGD PMID:8943043 MGI:84458 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 located_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta located_in ISO (MGI:3528790|PMID:15652482) RGD PMID:15652482 MGI:3528790 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Capn3 calpain 3 located_in IDA PMID:19144634 UniProt PMID:19144634 RGD:8553509 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Casq1 calsequestrin 1 IDA RGD PMID:11010809 RGD:2313244 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
JBrowse link
G Cav3 caveolin 3 located_in IDA
ISO
PMID:9925767
(MGI:3612003|PMID:16319126), (MGI:85086|PMID:9008709)
RGD PMID:9008709 PMID:16319126 PMID:16501018 PMID:9925767 MGI:3612003 MGI:85086, RGD:1599531, RGD:8553487 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cdh2 cadherin 2 located_in IDA PMID:15579534 BHF-UCL PMID:15579534 RGD:6484228 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cltc clathrin heavy chain IDA RGD PMID:7536412 RGD:2303181 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 IDA RGD PMID:11181181 RGD:1581466 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dysf dysferlin located_in
is_active_in
ISO
IBA
(PMID:17185750)
PMID:21873635
(MGI:3612003|PMID:16319126), (MGI:5545678|PMID:24302765), (MGI:5613103|PMID:24784578)
RGD PMID:16319126 PMID:17185750 PMID:24302765 PMID:24784578 PMID:21873635 MGI:3612003 MGI:5545678 MGI:5613103, RGD:13792537 NCBI chr 4:116,490,877...116,690,709
Ensembl chr 4:116,490,616...116,690,709
JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:12972433 RGD:1581834 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
JBrowse link
G Esr1 estrogen receptor 1 IDA RGD PMID:16876190 RGD:1601102 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ezr ezrin IDA RGD PMID:19028724 RGD:7207798 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G Fer1l5 fer-1-like family member 5 is_active_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 located_in IDA PMID:23532852 UniProt PMID:23532852 RGD:9685469 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IDA RGD PMID:23743348 RGD:11041118 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Igf1r insulin-like growth factor 1 receptor located_in IDA
ISO
(MGI:5510937|PMID:23695157) RGD PMID:23695157 PMID:23118311 MGI:5510937, RGD:10046017 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 located_in IDA PMID:10860776 UniProt PMID:10860776 RGD:10047321 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 located_in IDA
ISO
(MGI:4844023|PMID:20610380) RGD PMID:20610380 PMID:15647111 MGI:4844023, RGD:1598637 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 IDA RGD PMID:11181181 RGD:1581466 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 IDA RGD PMID:23640888 RGD:7247427 NCBI chr10:96,060,849...96,071,401
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 IDA RGD PMID:11561006 RGD:1581474 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 IDA RGD PMID:11561006 RGD:1581474 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 located_in ISO
IEA
(MGI:3771286|PMID:17110593)
GO_REF:0000107
RGD
Ensembl
PMID:17110593 GO_REF:0000107 MGI:3771286 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347
JBrowse link
G Msn moesin IDA RGD PMID:19028724 RGD:7207798 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628
JBrowse link
G Nos1 nitric oxide synthase 1 located_in ISO (MGI:5613473|PMID:19800018) RGD PMID:19800018 MGI:5613473 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein colocalizes_with ISO (MGI:5617336|PMID:24665357) RGD PMID:24665357 MGI:5617336 NCBI chr13:82,549,786...82,820,949 JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta located_in IEA
ISO
GO_REF:0000107
(MGI:3848765|PMID:19287093)
Ensembl
RGD
PMID:19287093 GO_REF:0000107 MGI:3848765 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha IDA RGD PMID:14569017 RGD:1304018 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628
JBrowse link
G Prkce protein kinase C, epsilon IDA RGD PMID:19525381 RGD:2317914 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Rdx radixin IDA RGD PMID:19028724 RGD:7207798 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678
JBrowse link
G Rtn2 reticulon 2 part_of
located_in
ISS
ISO
GO_REF:0000024
(MGI:4438323|PMID:19720795)
UniProt
RGD
PMID:19720795 GO_REF:0000024 MGI:4438323 NCBI chr 1:78,935,056...78,948,069
Ensembl chr 1:78,935,104...78,948,069
JBrowse link
G Ryr1 ryanodine receptor 1 located_in ISO (MGI:3529615|PMID:15536090), (MGI:5314827|PMID:22355118), (MGI:5510937|PMID:23695157), (MGI:84458|PMID:8943043) RGD PMID:8943043 PMID:15536090 PMID:22355118 PMID:23695157 MGI:3529615 MGI:5314827 MGI:5510937 MGI:84458 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 located_in IEA
ISO
GO_REF:0000107
(MGI:3625769|PMID:15746173)
Ensembl
RGD
PMID:15746173 GO_REF:0000107 MGI:3625769 NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 located_in ISO
IEA
(MGI:3056873|PMID:15272007), (MGI:4461877|PMID:18178574)
GO_REF:0000107
RGD
Ensembl
PMID:15272007 PMID:18178574 GO_REF:0000107 MGI:3056873 MGI:4461877 NCBI chr 1:86,353,917...86,363,836
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 located_in IEA
ISO
GO_REF:0000107
(MGI:3625769|PMID:15746173)
Ensembl
RGD
PMID:15746173 GO_REF:0000107 MGI:3625769 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 located_in IDA
IEA
ISO
GO_REF:0000107
(MGI:3625769|PMID:15746173), (MGI:4461877|PMID:18178574)
PMID:15579534
(PMID:15579534)
Ensembl
RGD
PMID:15579534 PMID:15746173 PMID:18178574 PMID:15579534 PMID:15579534 GO_REF:0000107 MGI:3625769 MGI:4461877, RGD:6484228, RGD:6484228 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Slc2a4 solute carrier family 2 member 4 IDA RGD PMID:20868366 RGD:7349316 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Slc30a1 solute carrier family 30 member 1 located_in IDA PMID:16741752 BHF-UCL PMID:16741752 RGD:8554228 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc8a1 solute carrier family 8 member A1 located_in IDA
ISO
TAS
(MGI:3528790|PMID:15652482), (MGI:3610760|PMID:16292983), (MGI:5314827|PMID:22355118)
PMID:11053140
PMID:1514597
RGD PMID:15652482 PMID:16292983 PMID:22355118 PMID:11121386 PMID:11053140 More... MGI:3528790 MGI:3610760 MGI:5314827, RGD:2316982, RGD:8554533, RGD:8553384 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IDA RGD PMID:20868366 RGD:7349316 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Sri sorcin IDA RGD PMID:16931553 RGD:7327199 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Stac SH3 and cysteine rich domain located_in ISO (MGI:5643852|PMID:23818578) RGD PMID:23818578 MGI:5643852 NCBI chr 8:111,530,800...111,653,228
Ensembl chr 8:111,530,800...111,654,008
JBrowse link
G Stbd1 starch binding domain 1 located_in ISO (PMID:9794794) RGD PMID:9794794 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:9281452 RGD:1625705 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Vdr vitamin D receptor IDA RGD PMID:20015453 RGD:4889912 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
L-type voltage-gated calcium channel complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C part_of IDA
IEA
ISS
ISO
PMID:15170217
GO_REF:0000107
GO_REF:0000024
(PMID:15454078)
Ensembl
BHF-UCL
RGD
PMID:15454078 PMID:15170217 GO_REF:0000024 GO_REF:0000107, RGD:11558004 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D part_of ISO
IEA
(PMID:1309651)
GO_REF:0000107
RGD
Ensembl
PMID:1309651 GO_REF:0000107 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S part_of ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 part_of IDA
IEA
ISO
IBA
PMID:25527503
GO_REF:0000107
(PMID:1309651)
PMID:21873635
Ensembl
RGD
PMID:1309651 PMID:25527503 PMID:21873635 GO_REF:0000107, RGD:11059598, RGD:13792537 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 part_of IEA
IDA
ISO
GO_REF:0000107
PMID:26680202
(PMID:1309651)
Ensembl
RGD
PMID:1309651 PMID:26680202 GO_REF:0000107, RGD:12907551 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 part_of IDA
IMP
PMID:15170217
PMID:10666413
PMID:25527503
UniProt
BHF-UCL
PMID:15170217 PMID:10666413 PMID:25527503 RGD:11558004, RGD:13673808, RGD:11059598 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 part_of ISS
IMP
IBA
GO_REF:0000024
PMID:9049149
PMID:21873635
UniProt PMID:9049149 PMID:21873635 GO_REF:0000024, RGD:69791, RGD:13792537 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 part_of ISS
ISO
GO_REF:0000024
(PMID:21127204)
UniProt
RGD
PMID:21127204 GO_REF:0000024 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 part_of IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:21127204)
UniProt
RGD
PMID:21127204 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 part_of ISO
ISS
(PMID:21127204)
GO_REF:0000024
RGD
UniProt
PMID:21127204 GO_REF:0000024 NCBI chr 1:65,800,820...65,831,165
Ensembl chr 1:65,800,355...65,831,006
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 part_of ISS
ISO
GO_REF:0000024
(MGI:6164122|PMID:21127204)
UniProt
RGD
PMID:21127204 GO_REF:0000024 MGI:6164122 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      T-tubule 71
        L-type voltage-gated calcium channel complex 11
Path 2
Term Annotations click to browse term
  cellular_component 19969
    cellular anatomical entity 19676
      membrane 9945
        plasma membrane 6245
          sarcolemma 179
            T-tubule 71
              L-type voltage-gated calcium channel complex 11
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