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ONTOLOGY REPORT - ANNOTATIONS


Term:T-tubule
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Accession:GO:0030315 term browser browse the term
Definition:Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
Synonyms:exact_synonym: transverse tubule
 related_synonym: triad
 xref: Wikipedia:T-tubule


show annotations for term's descendants           Sort by:
 
T-tubule term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 IDA RGD PMID:15647111 RGD:1598637 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcc9_v2 ATP binding cassette subfamily C member 9, variant 2 IDA RGD PMID:12738227 RGD:1598649
G Adra1a adrenoceptor alpha 1A IDA RGD PMID:18467629 RGD:5688343 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B IDA RGD PMID:18467629 RGD:5688343 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Ahnak AHNAK nucleoprotein NOT|colocalizes_with ISO (MGI:4838689|PMID:20833135) RGD PMID:20833135 MGI:4838689 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 NOT|colocalizes_with ISO (MGI:4838689|PMID:20833135) RGD PMID:20833135 MGI:4838689 NCBI chr 6:137,335,273...137,380,219 JBrowse link
G Akap6 A-kinase anchoring protein 6 IDA PMID:9679148 BHF-UCL PMID:9679148 RGD:8553491 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Akap7 A-kinase anchoring protein 7 IDA RGD PMID:14569017 RGD:1304018 NCBI chr 1:21,129,213...21,263,850
Ensembl chr 1:21,141,970...21,263,850
JBrowse link
G Ank2 ankyrin 2 ISO (MGI:2449848|PMID:12571597), (MGI:3610760|PMID:16292983) RGD PMID:12571597, PMID:16292983 MGI:2449848, MGI:3610760 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ank3 ankyrin 3 IDA PMID:15579534 BHF-UCL PMID:15579534 RGD:6484228 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Aqp4 aquaporin 4 IDA RGD PMID:20849844 RGD:5490121 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Asb15 ankyrin repeat and SOCS box containing 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:51,598,815...51,642,276
Ensembl chr 4:51,614,676...51,644,492
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IDA
ISO
PMID:17442282
(MGI:3610760|PMID:16292983)
UniProtKB:P05026 (PMID:19751721)
RGD PMID:16292983, PMID:19751721, PMID:17442282 MGI:3610760, RGD:6903343 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 IDA
ISO
(MGI:3610760|PMID:16292983)
UniProtKB:P05026 (PMID:19751721)
RGD PMID:16292983, PMID:19751721, PMID:17442282 MGI:3610760, RGD:6903343 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO UniProtKB:P05023|UniProtKB:P50993 (PMID:19751721) RGD PMID:19751721 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 ISO (PMID:19287093)
(MGI:3848765|PMID:19287093)
RGD PMID:19287093 MGI:3848765 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Bin1 bridging integrator 1 IDA
ISO
IEA
PMID:9182667
(MGI:5583915|PMID:24836577)
GO_REF:0000107
RGD
Ensembl
PMID:24836577, PMID:9182667 GO_REF:0000107, MGI:5583915, RGD:8553847 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IDA
ISO
TAS
(MGI:5314827|PMID:22355118)
PMID:11053140
RGD PMID:22355118, PMID:14569017, PMID:11053140 MGI:5314827, RGD:1304018, RGD:8554533 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S IEA
ISO
ISS
GO_REF:0000107
(MGI:1342891|PMID:10444070), (MGI:3529615|PMID:15536090), (MGI:84458|PMID:8943043)
GO_REF:0000024
(PMID:17204937)
Ensembl
RGD
UniProt
PMID:8943043, PMID:10444070, PMID:15536090, PMID:17204937 GO_REF:0000024, GO_REF:0000107, MGI:1342891, MGI:3529615, MGI:84458 NCBI chr13:52,889,570...52,964,558
Ensembl chr13:52,889,737...52,964,155
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO (MGI:3529615|PMID:15536090) RGD PMID:15536090 MGI:3529615 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 ISO (MGI:84458|PMID:8943043) RGD PMID:8943043 MGI:84458 NCBI chr10:85,954,138...85,974,764
Ensembl chr10:85,954,138...85,974,651
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta ISO (MGI:3528790|PMID:15652482) RGD PMID:15652482 MGI:3528790 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Capn3 calpain 3 IDA PMID:19144634 UniProt PMID:19144634 RGD:8553509 NCBI chr 3:112,227,486...112,278,408
Ensembl chr 3:112,228,720...112,278,408
JBrowse link
G Casq1 calsequestrin 1 IDA RGD PMID:11010809 RGD:2313244 NCBI chr13:90,592,676...90,602,365
Ensembl chr13:90,592,681...90,602,365
JBrowse link
G Cav3 caveolin 3 IDA
ISO
(MGI:3612003|PMID:16319126), (MGI:85086|PMID:9008709)
PMID:9925767
RGD PMID:9008709, PMID:16319126, PMID:16501018, PMID:9925767 MGI:3612003, MGI:85086, RGD:1599531, RGD:8553487 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Cdh2 cadherin 2 IDA PMID:15579534 BHF-UCL PMID:15579534 RGD:6484228 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cltc clathrin heavy chain IDA RGD PMID:7536412 RGD:2303181 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 IDA RGD PMID:11181181 RGD:1581466 NCBI chr11:72,164,566...72,378,895
Ensembl chr11:72,163,749...72,378,895
JBrowse link
G Dysf dysferlin ISO
IBA
(PMID:17185750)
(MGI:3612003|PMID:16319126), (MGI:5545678|PMID:24302765), (MGI:5613103|PMID:24784578)
PMID:21873635
RGD PMID:16319126, PMID:17185750, PMID:24302765, PMID:24784578, PMID:21873635 MGI:3612003, MGI:5545678, MGI:5613103, RGD:13792537 NCBI chr 4:115,700,942...115,901,873
Ensembl chr 4:115,712,850...115,901,873
JBrowse link
G Ednra endothelin receptor type A IDA RGD PMID:12972433 RGD:1581834 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Esr1 estrogen receptor 1 IDA RGD PMID:16876190 RGD:1601102 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ezr ezrin IDA RGD PMID:19028724 RGD:7207798 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fer1l5 fer-1-like family member 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:42,943,362...42,998,126
Ensembl chr 9:42,945,358...42,998,109
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IDA PMID:23532852 UniProt PMID:23532852 RGD:9685469 NCBI chr 1:89,484,197...89,488,279
Ensembl chr 1:89,484,199...89,488,223
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 IDA RGD PMID:23743348 RGD:11041118 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IDA
ISO
(MGI:5510937|PMID:23695157) RGD PMID:23695157, PMID:23118311 MGI:5510937, RGD:10046017 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 IDA PMID:10860776 UniProt PMID:10860776 RGD:10047321 NCBI chr 4:48,309,283...48,816,804 JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IDA
ISO
(MGI:4844023|PMID:20610380) RGD PMID:20610380, PMID:15647111 MGI:4844023, RGD:1598637 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 IDA RGD PMID:11181181 RGD:1581466 NCBI chr10:47,282,208...47,343,501
Ensembl chr10:47,281,786...47,341,411
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 IDA RGD PMID:23640888 RGD:7247427 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 IDA RGD PMID:11561006 RGD:1581474 NCBI chr 3:41,019,898...41,181,070
Ensembl chr 3:41,019,898...41,181,070
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 IDA RGD PMID:11561006 RGD:1581474 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 ISO (MGI:3771286|PMID:17110593) RGD PMID:17110593 MGI:3771286 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Msn moesin IDA RGD PMID:19028724 RGD:7207798 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Nos1 nitric oxide synthase 1 IEA
ISO
GO_REF:0000107
(MGI:5613473|PMID:19800018)
Ensembl
RGD
PMID:19800018 GO_REF:0000107, MGI:5613473 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein colocalizes_with ISO (MGI:5617336|PMID:24665357) RGD PMID:24665357 MGI:5617336 NCBI chr13:88,653,123...88,943,976 JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEA
ISO
GO_REF:0000107
(MGI:3848765|PMID:19287093)
Ensembl
RGD
PMID:19287093 GO_REF:0000107, MGI:3848765 NCBI chr15:4,209,702...4,236,895
Ensembl chr15:4,209,703...4,236,895
JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha IDA RGD PMID:14569017 RGD:1304018 NCBI chr 8:117,486,085...117,548,768
Ensembl chr 8:117,486,083...117,546,370
JBrowse link
G Prkce protein kinase C, epsilon IDA RGD PMID:19525381 RGD:2317914 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Rdx radixin IDA RGD PMID:19028724 RGD:7207798 NCBI chr 8:56,570,728...56,612,851
Ensembl chr 8:56,585,396...56,610,612
JBrowse link
G Rtn2 reticulon 2 ISO (MGI:4438323|PMID:19720795) RGD PMID:19720795 MGI:4438323 NCBI chr 1:80,195,594...80,208,449
Ensembl chr 1:80,195,532...80,208,448
JBrowse link
G Ryr1 ryanodine receptor 1 IEA
ISO
GO_REF:0000107
(MGI:3529615|PMID:15536090), (MGI:5314827|PMID:22355118), (MGI:5510937|PMID:23695157), (MGI:84458|PMID:8943043)
Ensembl
RGD
PMID:8943043, PMID:15536090, PMID:22355118, PMID:23695157 GO_REF:0000107, MGI:3529615, MGI:5314827, MGI:5510937, MGI:84458 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 IEA
ISO
GO_REF:0000107
(MGI:3625769|PMID:15746173)
Ensembl
RGD
PMID:15746173 GO_REF:0000107, MGI:3625769 NCBI chr 3:52,388,811...52,533,365
Ensembl chr 3:52,381,975...52,510,507
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 ISO (MGI:3056873|PMID:15272007), (MGI:4461877|PMID:18178574) RGD PMID:15272007, PMID:18178574 MGI:3056873, MGI:4461877 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 IEA
ISO
GO_REF:0000107
(MGI:3625769|PMID:15746173)
Ensembl
RGD
PMID:15746173 GO_REF:0000107, MGI:3625769 NCBI chr 3:51,687,910...51,822,008
Ensembl chr 3:51,687,809...51,822,250
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IDA
ISO
IEA
(MGI:3625769|PMID:15746173), (MGI:4461877|PMID:18178574)
GO_REF:0000107
(PMID:15579534)
RGD
Ensembl
PMID:15579534, PMID:15746173, PMID:18178574, PMID:15579534 GO_REF:0000107, MGI:3625769, MGI:4461877, RGD:6484228 NCBI chr 8:128,169,191...128,266,681
Ensembl chr 8:128,169,191...128,266,639
JBrowse link
G Slc2a4 solute carrier family 2 member 4 IDA RGD PMID:20868366 RGD:7349316 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc30a1 solute carrier family 30 member 1 IDA PMID:16741752 BHF-UCL PMID:16741752 RGD:8554228 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc8a1 solute carrier family 8 member A1 IDA
ISO
TAS
(MGI:3528790|PMID:15652482), (MGI:3610760|PMID:16292983), (MGI:5314827|PMID:22355118)
PMID:1514597
PMID:11053140
RGD PMID:15652482, PMID:16292983, PMID:22355118, PMID:11121386, PMID:1514597, PMID:11053140 MGI:3528790, MGI:3610760, MGI:5314827, RGD:2316982, RGD:8553384, RGD:8554533 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc9a1 solute carrier family 9 member A1 IDA RGD PMID:20868366 RGD:7349316 NCBI chr 5:151,573,122...151,626,360
Ensembl chr 5:151,573,092...151,627,316
JBrowse link
G Sri sorcin IDA RGD PMID:16931553 RGD:7327199 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983
JBrowse link
G Stac SH3 and cysteine rich domain ISO (MGI:5643852|PMID:23818578) RGD PMID:23818578 MGI:5643852 NCBI chr 8:119,820,664...119,941,867
Ensembl chr 8:119,821,901...119,889,661
JBrowse link
G Stbd1 starch binding domain 1 ISO (PMID:9794794) RGD PMID:9794794 NCBI chr14:16,976,355...16,979,760
Ensembl chr14:16,976,356...16,979,760
JBrowse link
G Tgfb3 transforming growth factor, beta 3 IDA RGD PMID:9281452 RGD:1625705 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Vdr vitamin D receptor IDA RGD PMID:20015453 RGD:4889912 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
L-type voltage-gated calcium channel complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO
ISS
IEA
IDA
(PMID:15454078)
GO_REF:0000024
GO_REF:0000107
PMID:15170217
RGD
BHF-UCL
Ensembl
PMID:15454078, PMID:15170217 GO_REF:0000024, GO_REF:0000107, RGD:11558004 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO
IEA
(PMID:1309651)
GO_REF:0000107
RGD
Ensembl
PMID:1309651 GO_REF:0000107 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1s calcium voltage-gated channel subunit alpha1 S ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr13:52,889,570...52,964,558
Ensembl chr13:52,889,737...52,964,155
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 ISO
IBA
IEA
IDA
(PMID:1309651)
PMID:21873635
GO_REF:0000107
PMID:25527503
RGD
Ensembl
PMID:1309651, PMID:21873635, PMID:25527503 GO_REF:0000107, RGD:13792537, RGD:11059598 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 ISO
IDA
IEA
(PMID:1309651)
PMID:26680202
GO_REF:0000107
RGD
Ensembl
PMID:1309651, PMID:26680202 GO_REF:0000107, RGD:12907551 NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA
IMP
PMID:25527503
PMID:10666413
PMID:15170217
BHF-UCL
UniProt
PMID:25527503, PMID:10666413, PMID:15170217 RGD:11059598, RGD:13673808, RGD:11558004 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 ISS
IBA
IMP
GO_REF:0000024
PMID:21873635
PMID:9049149
UniProt PMID:21873635, PMID:9049149 GO_REF:0000024, RGD:13792537, RGD:69791 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 ISS
ISO
GO_REF:0000024
(PMID:21127204)
UniProt
RGD
PMID:21127204 GO_REF:0000024 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:21127204)
UniProt
RGD
PMID:21127204, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:64,307,684...64,322,124
Ensembl chr 1:64,305,438...64,321,241
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 ISS
ISO
GO_REF:0000024
(PMID:21127204)
UniProt
RGD
PMID:21127204 GO_REF:0000024 NCBI chr 1:64,374,547...64,405,380
Ensembl chr 1:64,374,603...64,405,149
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 ISS
ISO
GO_REF:0000024
(MGI:6164122|PMID:21127204)
UniProt
RGD
PMID:21127204 GO_REF:0000024, MGI:6164122 NCBI chr 1:64,330,106...64,350,338
Ensembl chr 1:64,330,106...64,350,338
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein colocalizes_with IDA PMID:24665357 BHF-UCL PMID:24665357 RGD:10047296 NCBI chr13:88,653,123...88,943,976 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20602
    cellular anatomical entity 20292
      T-tubule 73
        L-type voltage-gated calcium channel complex 12
Path 2
Term Annotations click to browse term
  cellular_component 20602
    cellular anatomical entity 20292
      membrane 10190
        plasma membrane 6308
          sarcolemma 180
            T-tubule 73
              L-type voltage-gated calcium channel complex 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.