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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:intestinal cholesterol absorption
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Accession:GO:0030299 term browser browse the term
Definition:Uptake of cholesterol into the blood by absorption from the small intestine.



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intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in IC (MGI:2386529|PMID:12208868) BHF-UCL PMID:12208868 MGI:2386529 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in IC (MGI:2386529|PMID:12208868) BHF-UCL PMID:12208868 MGI:2386529 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Cd36 CD36 molecule involved_in IMP (MGI:3718873|PMID:17507371) UniProt PMID:17507371 MGI:3718873 NCBI chr 5:17,986,688...18,093,957
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cel carboxyl ester lipase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in IMP (MGI:6160379|PMID:29880681) UniProt PMID:29880681 MGI:6160379 NCBI chr15:99,676,351...99,773,292
Ensembl chr15:99,676,351...99,773,337
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO
IBA
IMP
(MGI:6201960|PMID:21873635)
(MGI:3041314|PMID:14976318)
MGI
GO_Central
UniProt
PMID:14976318 PMID:21873635 GO_REF:0000096 MGI:3041314 MGI:4834177 MGI:6201960 NCBI chr11:6,161,011...6,180,245
Ensembl chr11:6,161,013...6,180,143
JBrowse link
G Pnlip pancreatic lipase acts_upstream_of_or_within IMP (MGI:2679793|PMID:12915407) MGI PMID:12915407 MGI:2679793 NCBI chr19:58,658,797...58,670,231
Ensembl chr19:58,640,930...58,670,220
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-Coenzyme A acetyltransferase 2 involved_in IDA (MGI:5302163|PMID:22045928) CACAO PMID:22045928 MGI:5302163 NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 involved_in IDA (MGI:3588413|PMID:12393855) UniProt PMID:12393855 MGI:3588413 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in IMP (MGI:5574251|PMID:24650549) UniProt PMID:24650549 MGI:5574251 NCBI chr11:118,879,007...118,884,047
Ensembl chr11:118,879,014...118,884,047
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in IMP (MGI:5780634|PMID:26833026) UniProt PMID:26833026 MGI:5780634 NCBI chr 6:124,639,887...124,681,142
Ensembl chr 6:124,639,990...124,681,381
JBrowse link
regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A-I acts_upstream_of_or_within
involved_in
IDA
IBA
(MGI:1339009|PMID:10073953)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:10073953 PMID:21873635 MGI:1339009 MGI:6201960 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoa2 apolipoprotein A-II acts_upstream_of_or_within IMP (MGI:84652|PMID:8962133) MGI PMID:8962133 MGI:84652 NCBI chr 1:171,049,133...171,053,948
Ensembl chr 1:171,052,623...171,053,948
JBrowse link
G Apoa4 apolipoprotein A-IV acts_upstream_of_or_within
involved_in
IMP
IBA
(MGI:1096980|PMID:9323588)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:9323588 PMID:21873635 MGI:1096980 MGI:6201960 NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757
JBrowse link
G Lep leptin acts_upstream_of_or_within IDA (MGI:2386518|PMID:12114517) MGI PMID:12114517 MGI:2386518 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28659
    multicellular organismal process 9386
      digestion 135
        lipid digestion 20
          intestinal cholesterol absorption 17
            negative regulation of intestinal cholesterol absorption 2
            positive regulation of intestinal cholesterol absorption 4
            regulation of intestinal cholesterol absorption + 10
Path 2
Term Annotations click to browse term
  biological_process 28659
    localization 5484
      establishment of localization 4798
        transport 4597
          organic substance transport 2943
            lipid transport 476
              sterol transport 147
                cholesterol transport 142
                  intestinal cholesterol absorption 17
                    negative regulation of intestinal cholesterol absorption 2
                    positive regulation of intestinal cholesterol absorption 4
                    regulation of intestinal cholesterol absorption + 10
paths to the root