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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:intestinal cholesterol absorption
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Accession:GO:0030299 term browser browse the term
Definition:Uptake of cholesterol into the blood by absorption from the small intestine.



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intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:3718873|PMID:17507371)
UniProt
Ensembl
RGD
PMID:17507371 GO_REF:0000024 GO_REF:0000107 MGI:3718873 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd36l1 CD36 molecule like 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:17,424,749...17,465,808
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cel carboxyl ester lipase involved_in ISO
IEA
(PMID:12031288)
GO_REF:0000107
RGD
Ensembl
PMID:12031288 GO_REF:0000107 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Ldlr low density lipoprotein receptor involved_in ISO
IEA
(PMID:17142622)
GO_REF:0000107
RGD
Ensembl
PMID:17142622 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lima1 LIM domain and actin binding 1 involved_in ISO
IEA
(MGI:6160379|PMID:29880681)
GO_REF:0000107
RGD
Ensembl
PMID:29880681 GO_REF:0000107 MGI:6160379 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 involved_in ISO
IBA
(PMID:17140581)
(MGI:3041314|PMID:14976318)
PMID:21873635
RGD PMID:14976318 PMID:17140581 PMID:21873635 MGI:3041314, RGD:13792537 NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
JBrowse link
G Pnlip pancreatic lipase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2681122 (MGI:2679793|PMID:12915407)
Ensembl
RGD
PMID:12915407 GO_REF:0000107 MGI:2679793 NCBI chr 1:257,774,012...257,811,656
Ensembl chr 1:257,798,581...257,811,654
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 involved_in ISO (MGI:5302163|PMID:22045928) RGD PMID:22045928 MGI:5302163 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 involved_in ISO (MGI:3588413|PMID:12393855) RGD PMID:12393855 MGI:3588413 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5574251|PMID:24650549)
UniProt
RGD
PMID:24650549 GO_REF:0000024 MGI:5574251 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5780634|PMID:26833026)
UniProt
RGD
PMID:26833026 GO_REF:0000024 MGI:5780634 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:1339009|PMID:10073953)
PMID:21873635
RGD PMID:10073953 PMID:21873635 MGI:1339009, RGD:13792537 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoa2 apolipoprotein A2 acts_upstream_of_or_within ISO MGI:2157148 (MGI:84652|PMID:8962133) RGD PMID:8962133 MGI:84652 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
MGI:2157162 (MGI:1096980|PMID:9323588)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:9323588 PMID:21873635 GO_REF:0000107 MGI:1096980, RGD:13792537 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Lep leptin acts_upstream_of_or_within ISO (MGI:2386518|PMID:12114517) RGD PMID:12114517 MGI:2386518 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19553
    multicellular organismal process 9177
      digestion 136
        lipid digestion 21
          intestinal cholesterol absorption 18
            negative regulation of intestinal cholesterol absorption 2
            positive regulation of intestinal cholesterol absorption 4
            regulation of intestinal cholesterol absorption + 10
Path 2
Term Annotations click to browse term
  biological_process 19553
    localization 5546
      establishment of localization 4870
        transport 4545
          organic substance transport 2737
            lipid transport 480
              sterol transport 146
                cholesterol transport 132
                  intestinal cholesterol absorption 18
                    negative regulation of intestinal cholesterol absorption 2
                    positive regulation of intestinal cholesterol absorption 4
                    regulation of intestinal cholesterol absorption + 10
paths to the root