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ONTOLOGY REPORT - ANNOTATIONS

Term:bone mineralization
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Accession:GO:0030282 term browser browse the term
Definition:The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
Synonyms:narrow_synonym: bone calcification

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show annotations for term's descendants           Sort by:
bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated involved_in ISO (PMID:15920156)
(PMID:12082181), (PMID:15920156)
(MGI:2183534|PMID:10620060), (MGI:3033280|PMID:14982838), (MGI:5049900|PMID:20684022), (MGI:6827210|PMID:26457330), (MGI:6827471|PMID:11028439), (MGI:86401|PMID:9056646), (PMID:12082181)		 MGI
UniProt		 PMID:9056646 PMID:10620060 PMID:11028439 PMID:12082181 PMID:14982838 More... MGI:2183534 MGI:3033280 MGI:5049900 MGI:6827210 MGI:6827471 MGI:86401 NCBI chrNW_004624764:6,393,741...6,447,739
Ensembl chrNW_004624764:6,393,765...6,447,829 		JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624751:11,716,369...11,847,726
Ensembl chrNW_004624751:11,716,369...11,847,758 		JBrowse link
G Asgr2 asialoglycoprotein receptor 2 ISO RGD PMID:19841953 RGD:2316850 NCBI chrNW_004624786:9,728,949...9,753,438
Ensembl chrNW_004624786:9,728,336...9,753,434 		JBrowse link
G Aspn asporin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624868:3,897,633...3,920,307
Ensembl chrNW_004624868:3,897,514...3,920,383 		JBrowse link
G Atf4 activating transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624752:8,822,955...8,825,019
Ensembl chrNW_004624752:8,822,740...8,825,032 		JBrowse link
G Axin2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19623616) Ensembl
MGI		 PMID:19623616 GO_REF:0000107 NCBI chrNW_004624870:2,803,743...2,832,489
Ensembl chrNW_004624870:2,800,873...2,832,626 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (PMID:15657444), (PMID:19213727)
(PMID:19213727)		 MGI PMID:15657444 PMID:19213727 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO (PMID:19113921) BHF-UCL PMID:19113921 NCBI chrNW_004624736:18,958,081...18,960,617
Ensembl chrNW_004624736:18,958,069...18,960,617 		JBrowse link
G Clec3b C-type lectin domain family 3 member B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:75,531,320...75,535,875
Ensembl chrNW_004624730:75,530,770...75,536,248 		JBrowse link
G Col1a2 collagen type I alpha 2 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22910579) Ensembl
MGI		 PMID:22910579 GO_REF:0000107 NCBI chrNW_004624813:1,174,071...1,209,929
Ensembl chrNW_004624813:1,174,224...1,209,616 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19248115) Ensembl
MGI		 PMID:19248115 GO_REF:0000107 NCBI chrNW_004624745:31,125,136...31,140,126
Ensembl chrNW_004624745:31,125,265...31,139,318 		JBrowse link
G Comp cartilage oligomeric matrix protein acts_upstream_of_or_within ISO (PMID:27151399) MGI PMID:27151399 NCBI chrNW_004624908:1,870,975...1,877,434
Ensembl chrNW_004624908:1,871,002...1,877,369 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chrNW_004624734:3,363,084...3,372,790
Ensembl chrNW_004624734:3,363,001...3,372,694 		JBrowse link
G Duox2 dual oxidase 2 acts_upstream_of_or_within ISO (PMID:17440044) MGI PMID:17440044 NCBI chrNW_004624731:14,121,855...14,139,344
Ensembl chrNW_004624731:14,122,608...14,138,121 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:11997520) MGI PMID:11997520 NCBI chrNW_004624749:15,867,444...15,950,757
Ensembl chrNW_004624749:15,869,569...15,950,757 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in
acts_upstream_of		 ISO (PMID:28652107)
(PMID:12817751)
(PMID:31666661)
(PMID:26763447)
(PMID:12082181)
(PMID:24770645)
(PMID:25368121)
(PMID:21930712)
(PMID:15920156)		 MGI PMID:12082181 PMID:12817751 PMID:15920156 PMID:21930712 PMID:24770645 More... NCBI chrNW_004624753:5,918,005...5,983,480
Ensembl chrNW_004624753:5,917,689...5,982,308 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO (PMID:17020410) MGI PMID:17020410 NCBI chrNW_004624907:2,249,323...2,263,999
Ensembl chrNW_004624907:2,250,133...2,263,947 		JBrowse link
G Fbxl15 F-box and leucine rich repeat protein 15 involved_in ISO PMID:21572392 UniProt PMID:21572392 RGD:8554771 NCBI chrNW_004624831:1,823,244...1,826,646
Ensembl chrNW_004624831:1,823,832...1,826,646 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:12756187) MGI PMID:12756187 NCBI chrNW_004624737:25,052,698...25,158,346
Ensembl chrNW_004624737:25,052,606...25,158,529 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (MGI:4457789|PMID:20582225) BHF-UCL PMID:20582225 MGI:4457789 NCBI chrNW_004624755:25,633,690...25,647,361
Ensembl chrNW_004624755:25,635,165...25,646,932 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:16964445) MGI PMID:16964445 NCBI chrNW_004624764:11,482,719...11,513,215
Ensembl chrNW_004624764:11,489,685...11,513,270 		JBrowse link
G Fkrp fukutin related protein acts_upstream_of_or_within ISO (PMID:27109613), (PMID:29571322) MGI PMID:27109613 PMID:29571322 NCBI chrNW_004624832:6,849,001...6,858,931
Ensembl chrNW_004624832:6,849,005...6,857,898 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:15509771) MGI PMID:15509771 NCBI chrNW_004624738:10,370,479...10,391,623
Ensembl chrNW_004624738:10,370,103...10,391,623 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004624893:595,948...602,980
Ensembl chrNW_004624893:595,967...602,979 		JBrowse link
G Gla galactosidase alpha NOT|acts_upstream_of_or_within ISO (PMID:16697974) MGI PMID:16697974 NCBI chrNW_004624902:1,163,360...1,173,087
Ensembl chrNW_004624902:1,163,611...1,173,177 		JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15936336) Ensembl
MGI		 PMID:15936336 GO_REF:0000107 NCBI chrNW_004624797:13,234,741...13,678,542
Ensembl chrNW_004624797:13,230,932...13,678,742 		JBrowse link
G Gpnmb glycoprotein nmb ISO RGD PMID:11746512 RGD:632991 NCBI chrNW_004624739:7,358,824...7,386,852
Ensembl chrNW_004624739:7,359,741...7,387,279 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of ISO (PMID:17181398) MGI PMID:17181398 NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705 		JBrowse link
G Ibsp integrin binding sialoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25464126) Ensembl
TreeGrafter
MGI		 PMID:25464126 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624872:4,324,812...4,333,080
Ensembl chrNW_004624872:4,322,330...4,333,080 		JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO (PMID:23686339) MGI PMID:23686339 NCBI chrNW_004624818:5,165,923...5,174,761
Ensembl chrNW_004624818:5,165,876...5,174,828 		JBrowse link
G Ifitm5 interferon induced transmembrane protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18442316) Ensembl
TreeGrafter
MGI		 PMID:18442316 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624766:22,122,739...22,134,231
Ensembl chrNW_004624766:22,132,437...22,134,684 		JBrowse link
G Klf10 KLF transcription factor 10 acts_upstream_of_or_within ISO (PMID:15657444) MGI PMID:15657444 NCBI chrNW_004624763:19,582,019...19,592,447
Ensembl chrNW_004624763:19,581,730...19,587,730 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (MGI:4360132|PMID:19605502) UniProt PMID:19605502 MGI:4360132 NCBI chrNW_004624766:17,110,809...17,147,585
Ensembl chrNW_004624766:17,112,909...17,147,785 		JBrowse link
G LOC101700851 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:10,176,865...10,181,725
Ensembl chrNW_004624802:10,176,919...10,181,657 		JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO (PMID:19458888) MGI PMID:19458888 NCBI chrNW_004624774:20,116,625...20,137,767
Ensembl chrNW_004624774:20,116,970...20,134,355 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of ISO (PMID:11790802) MGI PMID:11790802 NCBI chrNW_004624767:20,845,949...20,861,169
Ensembl chrNW_004624767:20,845,949...20,860,673 		JBrowse link
G Mepe matrix extracellular phosphoglycoprotein acts_upstream_of ISO (PMID:12421822) MGI PMID:12421822 NCBI chrNW_004624872:4,345,045...4,358,456 JBrowse link
G Minpp1 multiple inositol-polyphosphate phosphatase 1 NOT|involved_in ISO (MGI:1888425|PMID:10938126) UniProt PMID:10938126 MGI:1888425 NCBI chrNW_004624791:13,647,307...13,705,976
Ensembl chrNW_004624791:13,647,376...13,689,441 		JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624918:2,228,688...2,239,852 JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 acts_upstream_of_or_within ISO (PMID:21406566) MGI PMID:21406566 NCBI chrNW_004624735:30,512,474...30,659,727
Ensembl chrNW_004624735:30,512,464...30,659,718 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004624904:2,324,186...2,332,204
Ensembl chrNW_004624904:2,322,758...2,332,194 		JBrowse link
G Nfix nuclear factor I X involved_in ISO (PMID:17353270) MGI PMID:17353270 NCBI chrNW_004624901:551,277...645,435
Ensembl chrNW_004624901:550,931...646,417 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843468) Ensembl
MGI		 PMID:15843468 GO_REF:0000107 NCBI chrNW_004624829:6,960,740...7,151,752
Ensembl chrNW_004624829:6,960,904...7,151,752 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 involved_in ISO (MGI:5049900|PMID:20684022), (MGI:6814708|PMID:17227223), (MGI:6827210|PMID:26457330) UniProt PMID:17227223 PMID:20684022 PMID:26457330 MGI:5049900 MGI:6814708 MGI:6827210 NCBI chrNW_004624795:5,456,029...5,462,529
Ensembl chrNW_004624795:5,456,029...5,461,587 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic acts_upstream_of_or_within ISO (PMID:21553379) MGI PMID:21553379 NCBI chrNW_004624738:23,759,382...23,768,743
Ensembl chrNW_004624738:23,759,398...23,771,639 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624816:10,087,866...10,185,004
Ensembl chrNW_004624816:10,164,666...10,184,994 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chrNW_004624814:6,897,818...6,904,890
Ensembl chrNW_004624814:6,897,857...6,903,728 		JBrowse link
G Pth parathyroid hormone involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19968565) Ensembl
MGI		 PMID:19968565 GO_REF:0000107 NCBI chrNW_004624766:5,489,857...5,492,777
Ensembl chrNW_004624766:5,489,800...5,492,871 		JBrowse link
G Pth1r parathyroid hormone 1 receptor acts_upstream_of_or_within ISO (PMID:11606467), (PMID:9832460) MGI PMID:9832460 PMID:11606467 NCBI chrNW_004624730:74,371,614...74,392,344
Ensembl chrNW_004624730:74,371,294...74,390,262 		JBrowse link
G Pthlh parathyroid hormone like hormone involved_in
acts_upstream_of
NOT|acts_upstream_of_or_within		 IEA
ISO		 (PMID:19968565)
(PMID:11606467)		 InterPro
MGI		 PMID:11606467 PMID:19968565 GO_REF:0000002 NCBI chrNW_004624778:8,007,358...8,019,538
Ensembl chrNW_004624778:8,008,056...8,019,612 		JBrowse link
G Ptn pleiotrophin acts_upstream_of_or_within ISO (PMID:12413943) MGI PMID:12413943 NCBI chrNW_004624765:17,523,086...17,625,264
Ensembl chrNW_004624765:17,522,916...17,548,184 		JBrowse link
G Rogdi rogdi atypical leucine zipper acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:38172607) MGI
Ensembl		 PMID:38172607 GO_REF:0000107 NCBI chrNW_004624824:2,649,694...2,655,728
Ensembl chrNW_004624824:2,650,116...2,655,716 		JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:23337931 RGD:11537369 NCBI chrNW_004624868:479,303...732,723
Ensembl chrNW_004624868:479,290...731,650 		JBrowse link
G Rspo2 R-spondin 2 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chrNW_004624763:23,067,682...23,182,945
Ensembl chrNW_004624763:23,067,691...23,182,059 		JBrowse link
G Runx2 RUNX family transcription factor 2 acts_upstream_of ISO (PMID:21930712) MGI PMID:21930712 NCBI chrNW_004624754:14,601,574...14,868,469
Ensembl chrNW_004624754:14,679,974...14,867,729 		JBrowse link
G Sbds SBDS ribosome maturation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:8,734,547...8,740,634
Ensembl chrNW_004624740:8,734,546...8,740,652 		JBrowse link
G Sbno2 strawberry notch homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23980096) Ensembl
MGI		 PMID:23980096 GO_REF:0000107 NCBI chrNW_004624828:7,479,695...7,532,961
Ensembl chrNW_004624828:7,478,970...7,537,428 		JBrowse link
G Slc24a3 solute carrier family 24 member 3 acts_upstream_of_or_within ISO (MGI:6104227|PMID:28602864) ARUK-UCL PMID:28602864 MGI:6104227 NCBI chrNW_004624741:19,808,186...20,298,772
Ensembl chrNW_004624741:19,808,255...20,297,056 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21788370)
(PMID:24585429)		 Ensembl
MGI		 PMID:21788370 PMID:24585429 GO_REF:0000107 NCBI chrNW_004624746:17,857,779...17,948,469
Ensembl chrNW_004624746:17,920,835...17,948,468 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of ISO (PMID:11371614) MGI PMID:11371614 NCBI chrNW_004624801:2,296,353...2,300,853
Ensembl chrNW_004624801:2,296,168...2,301,596 		JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO (PMID:12817751) MGI PMID:12817751 NCBI chrNW_004624872:4,505,796...4,513,247
Ensembl chrNW_004624872:4,505,522...4,513,742 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chrNW_004624737:33,341,574...33,526,814
Ensembl chrNW_004624737:33,341,029...33,526,928 		JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO (PMID:27188440) MGI PMID:27188440 NCBI chrNW_004624758:5,664,287...5,720,061
Ensembl chrNW_004624758:5,662,661...5,719,865 		JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chrNW_004624817:931,686...952,474
Ensembl chrNW_004624817:932,970...952,326 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (PMID:23686339) MGI PMID:23686339 NCBI chrNW_004624764:22,723,643...22,777,517
Ensembl chrNW_004624764:22,723,291...22,778,761 		JBrowse link
bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:22936354) MGI PMID:22936354 NCBI chrNW_004624816:6,896,176...7,077,758
Ensembl chrNW_004624816:6,894,413...7,077,883 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of ISO (PMID:21490954) MGI PMID:21490954 NCBI chrNW_004624738:7,958,610...8,100,223
Ensembl chrNW_004624738:7,603,252...8,100,369 		JBrowse link
G Ccdc154 coiled-coil domain containing 154 acts_upstream_of_or_within ISO (PMID:20121924) MGI PMID:20121924 NCBI chrNW_004624913:2,134,763...2,142,446
Ensembl chrNW_004624913:2,134,780...2,141,780 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:22359666)
(PMID:25260930)		 MGI PMID:22359666 PMID:25260930 NCBI chrNW_004624753:5,918,005...5,983,480
Ensembl chrNW_004624753:5,917,689...5,982,308 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO (PMID:26996322) MGI PMID:26996322 NCBI chrNW_004624730:38,003,437...38,144,312
Ensembl chrNW_004624730:38,003,902...38,144,277 		JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004624750:5,881,065...5,954,799
Ensembl chrNW_004624750:5,881,091...5,952,300 		JBrowse link
G Lep leptin ISO RGD PMID:21353474 RGD:5128507 NCBI chrNW_004624783:7,708,820...7,721,610
Ensembl chrNW_004624783:7,708,588...7,721,727 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 acts_upstream_of_or_within ISO (PMID:21272676) MGI PMID:21272676 NCBI chrNW_004624795:5,456,029...5,462,529
Ensembl chrNW_004624795:5,456,029...5,461,587 		JBrowse link
G Snx10 sorting nexin 10 acts_upstream_of_or_within ISO (PMID:25811986) MGI PMID:25811986 NCBI chrNW_004624739:4,210,840...4,274,768
Ensembl chrNW_004624739:4,209,036...4,233,519 		JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha 2-HS glycoprotein involved_in ISO
IEA		 RGD
Ensembl		 PMID:8702833 GO_REF:0000107 RGD:1626074 NCBI chrNW_004624730:70,149,461...70,156,058
Ensembl chrNW_004624730:70,149,850...70,156,039 		JBrowse link
G Bcor BCL6 corepressor involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chrNW_004624762:15,338,331...15,465,683
Ensembl chrNW_004624762:15,420,596...15,465,873 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISO (PMID:11165938) UniProt PMID:11165938 NCBI chrNW_004624772:18,234,537...18,239,896
Ensembl chrNW_004624772:18,233,727...18,240,601 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396 PMID:25479107 PMID:30111653 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chrNW_004624753:5,918,005...5,983,480
Ensembl chrNW_004624753:5,917,689...5,982,308 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:18282132) UniProt PMID:18282132 NCBI chrNW_004624860:1,478,712...1,486,808
Ensembl chrNW_004624860:1,479,303...1,486,323 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004624893:595,948...602,980
Ensembl chrNW_004624893:595,967...602,979 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004624804:1,606,182...1,620,932
Ensembl chrNW_004624804:1,608,757...1,620,938 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO (PMID:17181398) MGI PMID:17181398 NCBI chrNW_004624734:39,414,458...39,471,705
Ensembl chrNW_004624734:39,411,824...39,471,705 		JBrowse link
G LOC101724812 C-C chemokine receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624730:74,822,848...74,828,614
Ensembl chrNW_004624730:74,826,659...74,827,726 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO (PMID:11790802) MGI PMID:11790802 NCBI chrNW_004624767:20,845,949...20,861,169
Ensembl chrNW_004624767:20,845,949...20,860,673 		JBrowse link
G Mepe matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:22766095)
(PMID:12421822), (PMID:15843468)		 MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chrNW_004624872:4,345,045...4,358,456 JBrowse link
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004624904:2,324,186...2,332,204
Ensembl chrNW_004624904:2,322,758...2,332,194 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624758:22,065,448...22,182,604
Ensembl chrNW_004624758:22,124,836...22,182,605 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:11371614) MGI PMID:11371614 NCBI chrNW_004624801:2,296,353...2,300,853
Ensembl chrNW_004624801:2,296,168...2,301,596 		JBrowse link
G Srgn serglycin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:3,379,651...3,412,175
Ensembl chrNW_004624754:3,401,480...3,411,488 		JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004624804:1,606,182...1,620,932
Ensembl chrNW_004624804:1,608,757...1,620,938 		JBrowse link
G Pth parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chrNW_004624766:5,489,857...5,492,777
Ensembl chrNW_004624766:5,489,800...5,492,871 		JBrowse link
G Rflna refilin A acts_upstream_of_or_within ISO (PMID:24436304) MGI PMID:24436304 NCBI chrNW_004624747:23,766,756...23,775,238
Ensembl chrNW_004624747:23,766,856...23,774,397 		JBrowse link
G Rflnb refilin B acts_upstream_of_or_within ISO (PMID:24436304) MGI PMID:24436304 NCBI chrNW_004624786:3,793,266...3,801,894
Ensembl chrNW_004624786:3,793,302...3,801,630 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624732:7,929,997...8,004,235
Ensembl chrNW_004624732:7,929,583...8,005,072 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624866:539,967...619,575
Ensembl chrNW_004624866:539,894...620,302 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624731:2,557,993...2,600,250
Ensembl chrNW_004624731:2,566,063...2,600,035 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chrNW_004624743:9,849,070...10,292,392 JBrowse link
G Adrb2 adrenoceptor beta 2 acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chrNW_004624774:8,211,723...8,215,962
Ensembl chrNW_004624774:8,211,984...8,213,240 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624966:168,244...220,430
Ensembl chrNW_004624966:168,250...220,522 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 UniProt PMID:25589784 MGI:5634871 NCBI chrNW_004624816:6,896,176...7,077,758
Ensembl chrNW_004624816:6,894,413...7,077,883 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISO (MGI:5780494|PMID:26392310) UniProt PMID:26392310 MGI:5780494 NCBI chrNW_004624750:16,990,288...17,103,279 JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004624738:9,311,746...9,318,099
Ensembl chrNW_004624738:9,311,836...9,317,861 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (MGI:5009350|PMID:20675382)
(PMID:18436533), (PMID:20576608)		 BHF-UCL PMID:18436533 PMID:20576608 PMID:20675382 MGI:5009350 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:14749725), (PMID:18436533) RGD
UniProt
MGI		 PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chrNW_004624731:15,262,480...15,269,196
Ensembl chrNW_004624731:15,263,274...15,269,743 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624756:17,742,822...17,894,931
Ensembl chrNW_004624756:17,743,834...17,894,753 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624841:218,642...304,744
Ensembl chrNW_004624841:219,133...265,397 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624757:22,697,639...23,142,209
Ensembl chrNW_004624757:22,955,666...23,142,499 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004624765:13,849,689...13,950,839
Ensembl chrNW_004624765:13,857,062...13,947,683 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004624742:11,882,815...11,885,686
Ensembl chrNW_004624742:11,882,907...11,885,667 		JBrowse link
G Cd276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chrNW_004624781:691,348...703,202 JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chrNW_004624774:9,363,156...9,391,939
Ensembl chrNW_004624774:9,363,908...9,391,986 		JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17369251), (PMID:22615579) Ensembl
MGI		 PMID:17369251 PMID:22615579 GO_REF:0000107 NCBI chrNW_004624740:25,984,642...26,032,089
Ensembl chrNW_004624740:25,984,091...26,032,649 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chrNW_004624774:12,863,446...13,116,929
Ensembl chrNW_004624774:12,863,446...13,116,545 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004624755:25,633,690...25,647,361
Ensembl chrNW_004624755:25,635,165...25,646,932 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004624740:14,323,445...14,325,616
Ensembl chrNW_004624740:14,323,817...14,325,601 		JBrowse link
G Gpm6b glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624882:220,267...374,912
Ensembl chrNW_004624882:220,362...374,912 		JBrowse link
G Isg15 ISG15 ubiquitin like modifier involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004624818:8,510,657...8,511,749 JBrowse link
G Kl klotho involved_in ISO (PMID:12110410) UniProt PMID:12110410 NCBI chrNW_004624915:95,155...110,834 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chrNW_004624743:8,072,871...8,235,174
Ensembl chrNW_004624743:8,072,673...8,235,252 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004624766:11,921,570...12,734,032
Ensembl chrNW_004624766:11,921,650...12,737,576 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO (MGI:4950000|PMID:21262216) BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004624738:2,136,228...2,559,092
Ensembl chrNW_004624738:2,136,151...2,138,441 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624763:6,035,923...6,043,682
Ensembl chrNW_004624763:6,035,953...6,043,437 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chrNW_004624738:23,759,382...23,768,743
Ensembl chrNW_004624738:23,759,398...23,771,639 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chrNW_004624814:6,597,248...6,744,294
Ensembl chrNW_004624814:6,597,005...6,744,286 		JBrowse link
G Pth parathyroid hormone involved_in ISO
IEA		 RGD
Ensembl		 PMID:15758479 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chrNW_004624766:5,489,857...5,492,777
Ensembl chrNW_004624766:5,489,800...5,492,871 		JBrowse link
G Ptn pleiotrophin involved_in ISO (MGI:6294181|PMID:19442624) UniProt PMID:19442624 MGI:6294181 NCBI chrNW_004624765:17,523,086...17,625,264
Ensembl chrNW_004624765:17,522,916...17,548,184 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 involved_in ISO (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chrNW_004624780:725,992...833,419
Ensembl chrNW_004624780:779,900...832,137 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) UniProt PMID:25589784 NCBI chrNW_004624738:21,648,277...22,026,385
Ensembl chrNW_004624738:21,651,489...21,939,927 		JBrowse link
G Smad3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chrNW_004624781:5,795,652...5,890,047
Ensembl chrNW_004624781:5,795,652...5,890,371 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (MGI:6717031|PMID:33882302) UniProt PMID:33882302 MGI:6717031 NCBI chrNW_004624799:12,829,562...12,836,850
Ensembl chrNW_004624799:12,829,528...12,834,511 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chrNW_004624756:15,413,950...15,436,037
Ensembl chrNW_004624756:15,418,260...15,436,379 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624747:11,828,292...11,834,855 JBrowse link
G Wnt10b Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728361) Ensembl
MGI		 PMID:15728361 GO_REF:0000107 NCBI chrNW_004624816:3,221,573...3,227,102
Ensembl chrNW_004624816:3,210,828...3,227,096 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chrNW_004624767:19,844,996...19,859,274
Ensembl chrNW_004624767:19,844,884...19,858,950 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chrNW_004624738:7,958,610...8,100,223
Ensembl chrNW_004624738:7,603,252...8,100,369 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankh ANKH inorganic pyrophosphate transport regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10894769), (PMID:7276519) Ensembl
MGI		 PMID:7276519 PMID:10894769 GO_REF:0000107 NCBI chrNW_004624751:11,716,369...11,847,726
Ensembl chrNW_004624751:11,716,369...11,847,758 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624885:1,526,625...1,528,235
Ensembl chrNW_004624885:1,527,538...1,528,109 		JBrowse link
G Bmp2k BMP2 inducible kinase acts_upstream_of_or_within ISO (PMID:11500515) MGI PMID:11500515 NCBI chrNW_004624757:12,160,975...12,290,575
Ensembl chrNW_004624757:12,165,134...12,290,451 		JBrowse link
G Comp cartilage oligomeric matrix protein acts_upstream_of_or_within ISO (PMID:21350216) MGI PMID:21350216 NCBI chrNW_004624908:1,870,975...1,877,434
Ensembl chrNW_004624908:1,871,002...1,877,369 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (PMID:20564243) UniProt PMID:20564243 NCBI chrNW_004624826:1,225,217...1,255,889
Ensembl chrNW_004624826:1,173,621...1,249,692 		JBrowse link
G Ecm1 extracellular matrix protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20138147) MGI
TreeGrafter		 PMID:20138147 GO_REF:0000118 NCBI chrNW_004624772:18,234,537...18,239,896
Ensembl chrNW_004624772:18,233,727...18,240,601 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624753:5,918,005...5,983,480
Ensembl chrNW_004624753:5,917,689...5,982,308 		JBrowse link
G Fgf23 fibroblast growth factor 23 acts_upstream_of_or_within ISO (PMID:15579309) MGI PMID:15579309 NCBI chrNW_004624860:1,478,712...1,486,808
Ensembl chrNW_004624860:1,479,303...1,486,323 		JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:21346198) MGI PMID:21346198 NCBI chrNW_004624798:9,358,996...9,364,413
Ensembl chrNW_004624798:9,359,004...9,364,313 		JBrowse link
G LOC101700851 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:10,176,865...10,181,725
Ensembl chrNW_004624802:10,176,919...10,181,657 		JBrowse link
G Matn1 matrilin 1 acts_upstream_of_or_within ISO (PMID:16877353) MGI PMID:16877353 NCBI chrNW_004624764:14,188,421...14,197,244
Ensembl chrNW_004624764:14,188,140...14,195,654 		JBrowse link
G Mgp matrix Gla protein involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624752:23,146,025...23,149,266
Ensembl chrNW_004624752:23,146,166...23,149,048 		JBrowse link
G Nbr1 NBR1 autophagy cargo receptor involved_in ISO (MGI:4818844|PMID:20616007) BHF-UCL PMID:20616007 MGI:4818844 NCBI chrNW_004624795:1,160,588...1,185,919 JBrowse link
G Notum notum, palmitoleoyl-protein carboxylesterase acts_upstream_of_or_within ISO (PMID:30622831) MGI PMID:30622831 NCBI chrNW_004624801:10,795,603...10,802,394
Ensembl chrNW_004624801:10,791,939...10,802,463 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624857:4,143,269...4,147,877
Ensembl chrNW_004624857:4,143,270...4,147,877 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in ISO (PMID:30779713) UniProt PMID:30779713 NCBI chrNW_004624830:1,498,700...1,543,112
Ensembl chrNW_004624830:1,502,336...1,542,134 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chrNW_004624893:499,222...512,341
Ensembl chrNW_004624893:498,973...512,443 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:19597909) BHF-UCL PMID:19597909 NCBI chrNW_004624739:11,352,040...11,354,019
Ensembl chrNW_004624739:11,352,141...11,352,809 		JBrowse link
G Txlng taxilin gamma involved_in ISO (MGI:3587454|PMID:15911876), (MGI:5306578|PMID:19016261) UniProt PMID:15911876 PMID:19016261 MGI:3587454 MGI:5306578 NCBI chrNW_004624829:1,497,646...1,544,635
Ensembl chrNW_004624829:1,497,546...1,542,025 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chrNW_004624764:22,723,643...22,777,517
Ensembl chrNW_004624764:22,723,291...22,778,761 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    multicellular organismal process 7138
      ossification 422
        bone mineralization 134
          bone mineralization involved in bone maturation + 15
          negative regulation of bone mineralization + 19
          phosphatidylserine exposure on osteoblast involved in bone mineralization 0
          positive regulation of bone mineralization + 45
          regulation of bone mineralization + 80
Path 2
Term Annotations click to browse term
  biological_process 15225
    developmental process 6175
      anatomical structure development 5812
        tissue development 2074
          biomineral tissue development 177
            bone mineralization 134
              bone mineralization involved in bone maturation + 15
              negative regulation of bone mineralization + 19
              phosphatidylserine exposure on osteoblast involved in bone mineralization 0
              positive regulation of bone mineralization + 45
              regulation of bone mineralization + 80
paths to the root