Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:bone mineralization
go back to main search page
Accession:GO:0030282 term browser browse the term
Definition:The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
Synonyms:narrow_synonym: bone calcification

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase acts_upstream_of_or_within ISO (PMID:14716014) MGI PMID:14716014 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:111,055,583...111,124,143
Ensembl chr20:111,055,558...111,081,850 		JBrowse link
G ANKH ANKH inorganic pyrophosphate transport regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:14,401,681...14,559,342
Ensembl chr 4:14,408,116...14,559,454 		JBrowse link
G ASPN asporin involved_in ISO (PMID:19589127) UniProt PMID:19589127 NCBI chr12:102,972,652...102,999,248
Ensembl chr12:102,972,541...102,999,368 		JBrowse link
G ATF4 activating transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:22,092,046...22,094,184
Ensembl chr19:22,091,667...22,095,230 		JBrowse link
G AXIN2 axin 2 acts_upstream_of_or_within ISO (PMID:19623616) MGI PMID:19623616 NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15657444), (PMID:19213727)
(PMID:19213727)		 Ensembl
MGI		 PMID:15657444 PMID:19213727 GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in ISO (PMID:19113921) BHF-UCL PMID:19113921 NCBI chr12:64,859,301...64,865,676
Ensembl chr12:64,860,958...64,863,544 		JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:6,501,082...6,510,878
Ensembl chr22:6,501,102...6,512,314 		JBrowse link
G COL1A2 collagen type I alpha 2 chain acts_upstream_of_or_within ISO (PMID:22910579) MGI PMID:22910579 NCBI chr21:54,602,780...54,639,832
Ensembl chr21:54,602,398...54,632,780 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO (PMID:19248115) MGI PMID:19248115 NCBI chr 2:89,608,525...89,649,823 JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27151399) Ensembl
MGI		 PMID:27151399 GO_REF:0000107 NCBI chr 6:17,246,617...17,255,561
Ensembl chr 6:17,246,762...17,255,126 		JBrowse link
G CST5 cystatin D involved_in ISO (PMID:16680148) MGI PMID:16680148 NCBI chr 2:53,015,431...53,020,125
Ensembl chr 2:53,015,687...53,019,336 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chr24:78,687,542...78,695,782
Ensembl chr24:78,687,668...78,695,607 		JBrowse link
G DUOX2 dual oxidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17440044) Ensembl
MGI		 PMID:17440044 GO_REF:0000107 NCBI chr26:38,090,053...38,110,781
Ensembl chr26:38,090,648...38,109,636 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:11997520) MGI PMID:11997520 NCBI chr14:18,135,973...18,209,471
Ensembl chr14:18,136,291...18,209,457 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in
acts_upstream_of		 ISO (PMID:28652107)
(PMID:15920156)
(PMID:24770645)
(PMID:25368121)
(PMID:12082181)
(PMID:21930712)
(PMID:12817751)
(PMID:26763447)
(PMID:31666661)		 MGI PMID:12082181 PMID:12817751 PMID:15920156 PMID:21930712 PMID:24770645 More... NCBI chr13:41,670,416...41,755,549 JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17020410) Ensembl
MGI		 PMID:17020410 GO_REF:0000107 NCBI chr 6:38,804,296...38,823,229
Ensembl chr 6:38,801,423...38,823,073 		JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 involved_in ISO PMID:21572392 UniProt PMID:21572392 RGD:8554771 NCBI chr 9:95,450,709...95,454,830
Ensembl chr 9:95,452,809...95,459,661 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:12756187) MGI PMID:12756187 NCBI chr 9:114,234,344...114,354,736
Ensembl chr 9:114,234,250...114,354,704 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 involved_in ISO (MGI:4457789|PMID:20582225) BHF-UCL PMID:20582225 MGI:4457789 NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:16964445) MGI PMID:16964445 NCBI chr20:105,155,223...105,178,813
Ensembl chr20:105,165,043...105,179,067 		JBrowse link
G FKRP fukutin related protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27109613), (PMID:29571322) Ensembl
MGI		 PMID:27109613 PMID:29571322 GO_REF:0000107 NCBI chr 6:40,100,399...40,128,340
Ensembl chr 6:40,126,321...40,127,808 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15509771) Ensembl
MGI		 PMID:15509771 GO_REF:0000107 NCBI chr14:79,201,128...79,222,363
Ensembl chr14:79,201,649...79,222,373 		JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15005853) Ensembl
MGI		 PMID:15005853 GO_REF:0000107 NCBI chr  X:45,912,638...45,920,415
Ensembl chr  X:45,917,231...45,920,268 		JBrowse link
G GLA galactosidase alpha NOT|acts_upstream_of_or_within ISO (PMID:16697974) MGI PMID:16697974 NCBI chr  X:89,738,097...89,749,740
Ensembl chr  X:89,737,966...89,750,539 		JBrowse link
G GPC3 glypican 3 acts_upstream_of_or_within ISO (PMID:15936336) MGI PMID:15936336 NCBI chr  X:108,688,706...109,143,653 JBrowse link
G GPNMB glycoprotein nmb ISO RGD PMID:11746512 RGD:632991 NCBI chr21:35,037,197...35,066,143
Ensembl chr21:35,037,001...35,066,171 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17181398) Ensembl
MGI		 PMID:17181398 GO_REF:0000107 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G IBSP integrin binding sialoprotein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25464126) MGI
TreeGrafter		 PMID:25464126 GO_REF:0000118 NCBI chr 7:36,170,411...36,185,099
Ensembl chr 7:36,174,903...36,184,278 		JBrowse link
G ICMT isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO (PMID:23686339) MGI PMID:23686339 NCBI chr20:125,504,240...125,516,749
Ensembl chr20:125,504,325...125,515,160 		JBrowse link
G IFITM5 interferon induced transmembrane protein 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18442316) MGI
TreeGrafter		 PMID:18442316 GO_REF:0000118 NCBI chr 1:112,164...113,988
Ensembl chr 1:112,469...113,448 		JBrowse link
G KLF10 KLF transcription factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15657444) Ensembl
MGI		 PMID:15657444 GO_REF:0000107 NCBI chr 8:97,496,695...97,503,818
Ensembl chr 8:97,496,678...97,503,620 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:37,632,748...37,741,100
Ensembl chr 1:37,632,710...37,741,330 		JBrowse link
G LOC103242273 asialoglycoprotein receptor 2 ISO RGD PMID:19841953 RGD:2316850 NCBI chr16:6,458,498...6,474,692
Ensembl chr16:6,458,408...6,473,706 		JBrowse link
G LOX lysyl oxidase acts_upstream_of_or_within ISO (PMID:19458888) MGI PMID:19458888 NCBI chr23:25,158,458...25,172,763
Ensembl chr23:25,157,269...25,172,757 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chr 1:8,681,140...8,700,721
Ensembl chr 1:8,681,156...8,703,740 		JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of ISO (PMID:12421822) MGI PMID:12421822 NCBI chr 7:36,201,916...36,216,446 JBrowse link
G MINPP1 multiple inositol-polyphosphate phosphatase 1 NOT|involved_in ISO (MGI:1888425|PMID:10938126) UniProt PMID:10938126 MGI:1888425 NCBI chr 9:80,946,003...80,992,555
Ensembl chr 9:80,946,421...80,991,646 		JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:94,322,473...94,370,665
Ensembl chr 1:94,322,979...94,334,747 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 acts_upstream_of_or_within ISO (PMID:21406566) MGI PMID:21406566 NCBI chr 8:119,114,241...119,297,945
Ensembl chr 8:119,114,078...119,297,943 		JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of ISO (PMID:15005853) MGI PMID:15005853 NCBI chr11:50,409,023...50,417,931
Ensembl chr11:50,408,984...50,417,863 		JBrowse link
G NFIX nuclear factor I X involved_in ISO (PMID:17353270) MGI PMID:17353270 NCBI chr 6:11,705,323...11,778,943
Ensembl chr 6:11,706,060...11,776,083 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843468) Ensembl
MGI		 PMID:15843468 GO_REF:0000107 NCBI chr  X:20,507,619...20,733,367
Ensembl chr  X:20,522,498...20,734,599 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:69,626,026...69,633,196
Ensembl chr16:69,626,914...69,629,354 		JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic acts_upstream_of_or_within ISO (PMID:21553379) MGI PMID:21553379 NCBI chr14:65,203,757...65,214,386
Ensembl chr14:65,204,620...65,214,190 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in ISO (PMID:23913870) MGI PMID:23913870 NCBI chr11:38,696,771...38,819,324
Ensembl chr11:38,694,602...38,718,519 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G PTH parathyroid hormone acts_upstream_of ISO (PMID:19968565) MGI PMID:19968565 NCBI chr 1:51,327,555...51,330,810 JBrowse link
G PTH1R parathyroid hormone 1 receptor acts_upstream_of_or_within ISO (PMID:11606467), (PMID:9832460) MGI PMID:9832460 PMID:11606467 NCBI chr22:8,287,877...8,309,736
Ensembl chr22:8,289,398...8,311,256 		JBrowse link
G PTHLH parathyroid hormone like hormone involved_in
acts_upstream_of
NOT|acts_upstream_of_or_within		 IEA
ISO		 (PMID:19968565)
(PMID:11606467)		 InterPro
MGI		 PMID:11606467 PMID:19968565 GO_REF:0000002 NCBI chr11:27,682,300...27,694,808
Ensembl chr11:27,682,338...27,694,898 		JBrowse link
G PTN pleiotrophin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12413943) Ensembl
MGI		 PMID:12413943 GO_REF:0000107 NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215 		JBrowse link
G ROGDI rogdi atypical leucine zipper acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:38172607) MGI
Ensembl		 PMID:38172607 GO_REF:0000107 NCBI chr 5:4,466,954...4,472,967
Ensembl chr 5:4,466,824...4,472,780 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:23337931 RGD:11537369 NCBI chr12:102,172,288...102,397,297 JBrowse link
G RSPO2 R-spondin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19213727) Ensembl
MGI		 PMID:19213727 GO_REF:0000107 NCBI chr 8:102,632,060...102,804,181
Ensembl chr 8:102,632,060...102,801,911 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21930712) Ensembl
MGI		 PMID:21930712 GO_REF:0000107 NCBI chr17:26,679,386...26,807,812
Ensembl chr17:26,683,175...26,807,319 		JBrowse link
G SBDS SBDS ribosome maturation factor involved_in ISO (PMID:17920346) UniProt PMID:17920346 NCBI chr28:2,527,395...2,535,152
Ensembl chr28:2,527,020...2,535,147 		JBrowse link
G SBNO2 strawberry notch homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23980096) Ensembl
MGI		 PMID:23980096 GO_REF:0000107 NCBI chr 6:877,066...950,663
Ensembl chr 6:877,049...931,433 		JBrowse link
G SLC24A3 solute carrier family 24 member 3 acts_upstream_of_or_within ISO (MGI:6104227|PMID:28602864) ARUK-UCL PMID:28602864 MGI:6104227 NCBI chr 2:48,238,872...48,736,517 JBrowse link
G SLC24A3 solute carrier family 24 member 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 2:48,687,887...48,737,156 JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21788370)
(PMID:24585429)		 Ensembl
MGI		 PMID:21788370 PMID:24585429 GO_REF:0000107 NCBI chr 5:58,965,965...59,057,823
Ensembl chr 5:59,029,093...59,059,577 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898 		JBrowse link
G SPP1 secreted phosphoprotein 1 involved_in ISO (PMID:12817751) MGI PMID:12817751 NCBI chr 7:36,337,165...36,344,927
Ensembl chr 7:36,338,386...36,344,407 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chr 9:105,828,834...106,047,810 JBrowse link
G TMEM38B transmembrane protein 38B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27188440) Ensembl
MGI		 PMID:27188440 GO_REF:0000107 NCBI chr12:33,759,311...33,840,357
Ensembl chr12:33,759,157...33,840,009 		JBrowse link
G WNT11 Wnt family member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19213727) Ensembl
MGI		 PMID:19213727 GO_REF:0000107 NCBI chr 1:67,393,975...67,427,247
Ensembl chr 1:67,399,074...67,418,509 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23686339) Ensembl
MGI		 PMID:23686339 GO_REF:0000107 NCBI chr20:92,605,495...92,648,110
Ensembl chr20:92,605,309...92,648,114 		JBrowse link
bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:22936354) MGI PMID:22936354 NCBI chr11:41,420,206...41,633,323
Ensembl chr11:41,419,901...41,633,347 		JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of ISO (PMID:21490954) MGI PMID:21490954 NCBI chr14:81,770,068...81,919,200 JBrowse link
G CCDC154 coiled-coil domain containing 154 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20121924) Ensembl
TreeGrafter
MGI		 PMID:20121924 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:1,323,406...1,333,676
Ensembl chr 5:1,322,933...1,333,122 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:22359666)
(PMID:25260930)		 MGI PMID:22359666 PMID:25260930 NCBI chr13:41,670,416...41,755,549 JBrowse link
G IFT80 intraflagellar transport 80 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26996322) Ensembl
MGI		 PMID:26996322 GO_REF:0000107 NCBI chr15:30,441,724...30,577,437
Ensembl chr15:30,461,526...30,577,484 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G LEP leptin ISO RGD PMID:21353474 RGD:5128507 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21272676) Ensembl
TreeGrafter
MGI		 PMID:21272676 GO_REF:0000107 GO_REF:0000118 NCBI chr16:69,626,026...69,633,196
Ensembl chr16:69,626,914...69,629,354 		JBrowse link
G SNX10 sorting nexin 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25811986) Ensembl
MGI		 PMID:25811986 GO_REF:0000107 NCBI chr21:31,999,253...32,044,967
Ensembl chr21:31,998,277...32,081,843 		JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein involved_in ISO
IEA		 RGD
Ensembl		 PMID:8702833 GO_REF:0000107 RGD:1626074 NCBI chr15:2,809,234...2,818,382
Ensembl chr15:2,809,028...2,817,514 		JBrowse link
G BCOR BCL6 corepressor involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr  X:37,191,242...37,319,966
Ensembl chr  X:37,192,874...37,319,782 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:7,634,205...7,641,380 JBrowse link
G ECM1 extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396 PMID:25479107 PMID:30111653 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chr13:41,670,416...41,755,549 JBrowse link
G FGF23 fibroblast growth factor 23 involved_in ISO (PMID:18282132) UniProt PMID:18282132 NCBI chr11:4,398,318...4,408,415
Ensembl chr11:4,398,675...4,407,209 		JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15005853) Ensembl
MGI		 PMID:15005853 GO_REF:0000107 NCBI chr  X:45,912,638...45,920,415
Ensembl chr  X:45,917,231...45,920,268 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:50,155,496...50,156,047 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17181398) Ensembl
MGI		 PMID:17181398 GO_REF:0000107 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G LOC103242767 C-C motif chemokine 3 involved_in ISO (PMID:21403648) UniProt PMID:21403648 NCBI chr16:29,887,799...29,897,664
Ensembl chr16:29,887,883...29,897,544 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chr 1:8,681,140...8,700,721
Ensembl chr 1:8,681,156...8,703,740 		JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:12421822), (PMID:15843468)
(PMID:22766095)		 MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chr 7:36,201,916...36,216,446 JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chr11:50,409,023...50,417,931
Ensembl chr11:50,408,984...50,417,863 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898 		JBrowse link
G SRGN serglycin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:62,217,836...62,235,110
Ensembl chr 9:62,217,525...62,235,238 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:50,155,496...50,156,047 JBrowse link
G LOC103239345 refilin-A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24436304) Ensembl
TreeGrafter
MGI		 PMID:24436304 GO_REF:0000107 GO_REF:0000118 NCBI chr11:119,497,097...119,666,178
Ensembl chr11:119,647,606...119,668,003 		JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:51,327,555...51,330,810 JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24436304) Ensembl
TreeGrafter
MGI		 PMID:24436304 GO_REF:0000107 GO_REF:0000118 NCBI chr16:269,395...278,249
Ensembl chr16:271,418...278,115 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr10:43,139,396...43,281,024
Ensembl chr10:43,139,528...43,281,177 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr10:33,223,902...33,311,257
Ensembl chr10:33,224,099...33,307,720 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr15:923,222...962,438 JBrowse link
G ACVR2B activin A receptor type 2B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr15:933,070...939,419 JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chr 4:84,498,630...85,082,813
Ensembl chr 4:84,498,573...85,083,504 		JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15724149) Ensembl
MGI		 PMID:15724149 GO_REF:0000107 NCBI chr23:51,445,920...51,447,942
Ensembl chr23:51,446,154...51,447,401 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G ANO6 anoctamin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:41,420,206...41,633,323
Ensembl chr11:41,419,901...41,633,347 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:84,985,957...85,053,923
Ensembl chr11:84,989,169...85,103,957 		JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:80,399,298...80,404,539
Ensembl chr14:80,399,513...80,404,280 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 ISO (PMID:14749725), (PMID:18436533) RGD
UniProt
MGI		 PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chr24:31,097,673...31,104,774
Ensembl chr24:31,097,538...31,101,225 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr17:64,279,243...64,436,356
Ensembl chr17:64,280,609...64,435,382 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,944,463...45,108,832
Ensembl chr 9:44,941,460...45,027,275 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:43,349,364...43,397,745 JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:88,103,442...88,302,578
Ensembl chr10:88,106,072...88,303,734 		JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:47,783,270...47,786,216
Ensembl chr20:47,783,935...47,785,997 		JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chr26:9,772,948...9,794,395 JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr23:52,663,290...52,723,652
Ensembl chr23:52,664,076...52,697,304 		JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:31,204,652...31,476,677
Ensembl chr23:31,204,391...31,475,820 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr27:46,958,444...46,974,032
Ensembl chr27:46,957,254...46,973,392 		JBrowse link
G FZD9 frizzled class receptor 9 involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chr28:9,621,434...9,623,769
Ensembl chr28:9,621,770...9,623,545 		JBrowse link
G GPM6B glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:12,258,386...12,429,883 JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chr20:130,419,909...130,421,409
Ensembl chr20:130,419,782...130,421,380 		JBrowse link
G KL klotho involved_in ISO (PMID:12110410) UniProt PMID:12110410 NCBI chr 3:11,755,015...11,799,537
Ensembl chr 3:11,755,016...11,797,596 		JBrowse link
G LOC103246914 FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr28:21,299,235...21,371,603
Ensembl chr28:21,299,213...21,371,577 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chr 4:82,702,378...82,887,491
Ensembl chr 4:82,706,738...82,788,152 		JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr25:6,901,891...6,954,556
Ensembl chr25:6,902,425...6,954,526 		JBrowse link
G NELL1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chr 1:43,416,052...44,335,894
Ensembl chr 1:43,415,553...44,335,381 		JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:88,364,115...88,371,258
Ensembl chr14:88,364,166...88,371,263 		JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:93,831,218...93,839,098
Ensembl chr 8:93,831,480...93,839,263 		JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059 		JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chr14:65,203,757...65,214,386
Ensembl chr14:65,204,620...65,214,190 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431 		JBrowse link
G PTH parathyroid hormone involved_in ISO (PMID:17696759) RGD
UniProt		 PMID:15758479 PMID:17696759 PMID:22445539 RGD:7207452 RGD:7242906 NCBI chr 1:51,327,555...51,330,810 JBrowse link
G PTN pleiotrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:105,911,171...106,027,108
Ensembl chr21:105,911,120...106,027,215 		JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:40,413,070...40,535,002
Ensembl chr 8:40,412,958...40,469,896 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) UniProt PMID:25589784 NCBI chr14:66,813,523...67,210,261 JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr14:66,871,034...66,970,731 JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr26:16,319,959...16,446,472
Ensembl chr26:16,320,933...16,446,527 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:6,392,131...6,399,456
Ensembl chr13:6,392,025...6,398,564 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr17:61,750,757...61,769,041 JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:103,787,911...103,796,217
Ensembl chr11:103,788,407...103,789,249 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361) MGI PMID:15728361 NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chr 1:7,708,595...7,724,634
Ensembl chr 1:7,705,725...7,724,589 		JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr14:81,770,068...81,919,200 JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKH ANKH inorganic pyrophosphate transport regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10894769), (PMID:7276519) Ensembl
MGI		 PMID:7276519 PMID:10894769 GO_REF:0000107 NCBI chr 4:14,401,681...14,559,342
Ensembl chr 4:14,408,116...14,559,454 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in IEA InterPro GO_REF:0000002 NCBI chr20:7,623,716...7,626,353
Ensembl chr20:7,623,883...7,624,812 		JBrowse link
G BMP2K BMP2 inducible kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11500515) Ensembl
MGI		 PMID:11500515 GO_REF:0000107 NCBI chr 7:27,222,107...27,362,955
Ensembl chr 7:27,270,000...27,358,598 		JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21350216) Ensembl
MGI		 PMID:21350216 GO_REF:0000107 NCBI chr 6:17,246,617...17,255,561
Ensembl chr 6:17,246,762...17,255,126 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:53,675,704...53,681,372
Ensembl chr11:53,675,226...53,680,443 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:1,298,636...1,451,872
Ensembl chr20:1,299,574...1,359,674 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20138147) Ensembl
TreeGrafter
MGI		 PMID:20138147 GO_REF:0000107 GO_REF:0000118
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr13:41,681,213...41,755,382 JBrowse link
G FGF23 fibroblast growth factor 23 acts_upstream_of_or_within ISO (PMID:15579309) MGI PMID:15579309 NCBI chr11:4,398,318...4,408,415
Ensembl chr11:4,398,675...4,407,209 		JBrowse link
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21346198) Ensembl
MGI		 PMID:21346198 GO_REF:0000107 NCBI chr13:52,397,291...52,410,341
Ensembl chr13:52,396,109...52,410,339 		JBrowse link
G LOC103243743 notum, palmitoleoyl-protein carboxylesterase acts_upstream_of_or_within ISO (PMID:30622831) MGI PMID:30622831 NCBI chr16:73,826,835...73,835,453 JBrowse link
G MATN1 matrilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16877353) Ensembl
MGI		 PMID:16877353 GO_REF:0000107 NCBI chr20:102,115,918...102,126,227
Ensembl chr20:102,115,999...102,125,811 		JBrowse link
G MGP matrix Gla protein involved_in IEA InterPro GO_REF:0000002 NCBI chr11:14,776,668...14,780,796
Ensembl chr11:14,776,209...14,780,947 		JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in ISO (MGI:4818844|PMID:20616007) BHF-UCL PMID:20616007 MGI:4818844 NCBI chr16:63,108,946...63,150,010
Ensembl chr16:63,110,548...63,144,481 		JBrowse link
G NOTUM notum, palmitoleoyl-protein carboxylesterase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:73,826,096...73,833,701 JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:32,109,436...32,117,015
Ensembl chr20:32,110,819...32,111,967 		JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in ISO (PMID:30779713) UniProt PMID:30779713 NCBI chr 7:55,752,419...55,843,408
Ensembl chr 7:55,753,270...55,838,914 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chr  X:45,820,114...45,834,727
Ensembl chr  X:45,822,453...45,834,917 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:39,040,178...39,042,384
Ensembl chr21:39,040,547...39,041,146 		JBrowse link
G TXLNG taxilin gamma involved_in ISO (MGI:3587454|PMID:15911876), (MGI:5306578|PMID:19016261) UniProt PMID:15911876 PMID:19016261 MGI:3587454 MGI:5306578 NCBI chr  X:15,213,058...15,268,388
Ensembl chr  X:15,213,156...15,265,635 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23695662) Ensembl
MGI		 PMID:23695662 GO_REF:0000107 NCBI chr20:92,605,495...92,648,110
Ensembl chr20:92,605,309...92,648,114 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17080
    multicellular organismal process 7314
      ossification 446
        bone mineralization 145
          bone mineralization involved in bone maturation + 16
          negative regulation of bone mineralization + 21
          phosphatidylserine exposure on osteoblast involved in bone mineralization 0
          positive regulation of bone mineralization + 49
          regulation of bone mineralization + 88
Path 2
Term Annotations click to browse term
  biological_process 17080
    developmental process 6685
      anatomical structure development 6282
        tissue development 2214
          biomineral tissue development 190
            bone mineralization 145
              bone mineralization involved in bone maturation + 16
              negative regulation of bone mineralization + 21
              phosphatidylserine exposure on osteoblast involved in bone mineralization 0
              positive regulation of bone mineralization + 49
              regulation of bone mineralization + 88
paths to the root