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ONTOLOGY REPORT - ANNOTATIONS

Term:bone mineralization
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Accession:GO:0030282 term browser browse the term
Definition:The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
Synonyms:narrow_synonym: bone calcification


show annotations for term's descendants           Sort by:
bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14716014) Ensembl
MGI		 PMID:14716014 GO_REF:0000107 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ALPL alkaline phosphatase, biomineralization associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,559,791...77,614,102
Ensembl chr 2:77,559,791...77,614,820 		JBrowse link
G ANKH ANKH inorganic pyrophosphate transport regulator involved_in ISO (PMID:12817751) MGI PMID:12817751 NCBI chr 4:88,149,250...88,263,926
Ensembl chr 4:88,149,257...88,272,464 		JBrowse link
G ASGR2 asialoglycoprotein receptor 2 ISO RGD PMID:19841953 RGD:2316850 NCBI chr 5:32,112,365...32,123,785
Ensembl chr 5:32,111,984...32,119,003 		JBrowse link
G ASPN asporin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:98,881,610...98,905,641
Ensembl chr 1:98,881,690...98,904,945 		JBrowse link
G ATF4 activating transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993 		JBrowse link
G AXIN2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19623616) Ensembl
MGI		 PMID:19623616 GO_REF:0000107 NCBI chr 9:14,559,476...14,588,950
Ensembl chr 9:14,559,388...14,588,530 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19213727)
(PMID:15657444), (PMID:19213727)		 Ensembl
MGI		 PMID:15657444 PMID:19213727 GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:43,319,786...43,332,161
Ensembl chr20:43,324,231...43,332,135 		JBrowse link
G COL1A2 collagen type I alpha 2 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22910579) Ensembl
MGI		 PMID:22910579 GO_REF:0000107 NCBI chr14:19,883,731...19,919,527
Ensembl chr14:19,883,868...19,919,527 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19248115) Ensembl
MGI		 PMID:19248115 GO_REF:0000107 NCBI chr31:39,301,718...39,319,895
Ensembl chr31:39,301,748...39,448,062 		JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27151399) Ensembl
MGI		 PMID:27151399 GO_REF:0000107 NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chr 8:68,961,975...68,970,106
Ensembl chr 8:68,961,744...68,972,761 		JBrowse link
G DUOX2 dual oxidase 2 acts_upstream_of_or_within ISO (PMID:17440044) MGI PMID:17440044 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:11997520) MGI PMID:11997520 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in
acts_upstream_of		 ISO (PMID:28652107)
(PMID:24770645)
(PMID:15920156)
(PMID:25368121)
(PMID:21930712)
(PMID:12817751)
(PMID:31666661)
(PMID:12082181)
(PMID:26763447)		 MGI PMID:12082181 PMID:12817751 PMID:15920156 PMID:21930712 PMID:24770645 More... NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718 		JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17020410) Ensembl
MGI		 PMID:17020410 GO_REF:0000107 NCBI chr 1:110,173,781...110,191,612
Ensembl chr 1:110,173,715...110,190,125 		JBrowse link
G FBXL15 F-box and leucine rich repeat protein 15 involved_in ISS UniProt GO_REF:0000024 NCBI chr28:14,927,740...14,929,867
Ensembl chr28:14,927,532...14,929,863 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:12756187) UniProt
MGI		 PMID:12756187 GO_REF:0000024 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 involved_in ISO (MGI:4457789|PMID:20582225) BHF-UCL PMID:20582225 MGI:4457789 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16964445) Ensembl
MGI		 PMID:16964445 GO_REF:0000107 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251 		JBrowse link
G FKRP fukutin related protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27109613), (PMID:29571322) Ensembl
MGI		 PMID:27109613 PMID:29571322 GO_REF:0000107 NCBI chr 1:109,166,527...109,177,393
Ensembl chr 1:109,168,644...109,178,319 		JBrowse link
G FOSL2 FOS like 2, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15509771) Ensembl
MGI		 PMID:15509771 GO_REF:0000107 NCBI chr17:22,340,469...22,364,994
Ensembl chr17:22,341,322...22,361,772 		JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15005853) Ensembl
MGI		 PMID:15005853 GO_REF:0000107 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303 		JBrowse link
G GLA galactosidase alpha NOT|acts_upstream_of_or_within ISO (PMID:16697974) MGI PMID:16697974 NCBI chr  X:75,311,536...75,320,391
Ensembl chr  X:75,311,536...75,320,249 		JBrowse link
G GPC3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15936336) Ensembl
MGI		 PMID:15936336 GO_REF:0000107 NCBI chr  X:104,313,426...104,751,215
Ensembl chr  X:104,313,591...104,751,756 		JBrowse link
G GPNMB glycoprotein nmb ISO RGD PMID:11746512 RGD:632991 NCBI chr14:36,919,184...36,947,023
Ensembl chr14:36,919,296...36,946,643 		JBrowse link
G GPR153 G protein-coupled receptor 153 acts_upstream_of_or_within ISO (PMID:23686339) MGI PMID:23686339 NCBI chr 5:60,119,793...60,128,531
Ensembl chr 5:60,123,054...60,149,027 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of		 IEA
ISO		 (PMID:17181398) Ensembl
MGI		 PMID:17181398 GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G IBSP integrin binding sialoprotein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25464126) Ensembl
MGI		 PMID:25464126 GO_REF:0000107 NCBI chr32:11,187,188...11,200,860
Ensembl chr32:11,187,160...11,200,846 		JBrowse link
G IFITM5 interferon induced transmembrane protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18442316) Ensembl
MGI		 PMID:18442316 GO_REF:0000107
G KLF10 KLF transcription factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15657444) Ensembl
MGI		 PMID:15657444 GO_REF:0000107 NCBI chr13:4,216,745...4,223,708
Ensembl chr13:4,218,084...4,223,691 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:47,952,019...47,995,530
Ensembl chr21:47,952,890...47,996,288 		JBrowse link
G LOX lysyl oxidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19458888) Ensembl
MGI		 PMID:19458888 GO_REF:0000107 NCBI chr11:12,023,645...12,040,015
Ensembl chr11:12,027,250...12,039,819 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433 		JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of ISO (PMID:12421822) MGI PMID:12421822 NCBI chr32:11,212,531...11,222,805
Ensembl chr32:11,212,531...11,222,805 		JBrowse link
G MINPP1 multiple inositol-polyphosphate phosphatase 1 NOT|involved_in ISO (MGI:1888425|PMID:10938126) UniProt PMID:10938126 MGI:1888425 NCBI chr26:37,585,096...37,629,221
Ensembl chr26:37,586,727...37,626,618 		JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,793,568...28,864,832
Ensembl chr 5:28,850,522...28,864,121 		JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 acts_upstream_of_or_within ISO (PMID:21406566) MGI PMID:21406566 NCBI chr13:22,633,001...22,794,960
Ensembl chr13:22,635,230...22,794,453 		JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of ISO (PMID:15005853) MGI PMID:15005853 NCBI chr27:1,003,551...1,010,514
Ensembl chr27:1,003,816...1,010,264 		JBrowse link
G NFIX nuclear factor I X involved_in ISO (PMID:17353270) MGI PMID:17353270 NCBI chr20:49,117,087...49,187,023
Ensembl chr20:49,117,943...49,214,788 		JBrowse link
G PHEX phosphate regulating endopeptidase X-linked involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843468) Ensembl
MGI		 PMID:15843468 GO_REF:0000107 NCBI chr  X:17,830,714...18,038,755
Ensembl chr  X:17,829,158...18,035,775 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 involved_in ISO (MGI:5049900|PMID:20684022), (MGI:6814708|PMID:17227223), (MGI:6827210|PMID:26457330) UniProt PMID:17227223 PMID:20684022 PMID:26457330 MGI:5049900 MGI:6814708 MGI:6827210 NCBI chr 9:25,385,313...25,392,278
Ensembl chr 9:25,385,396...25,392,242 		JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21553379) Ensembl
MGI		 PMID:21553379 GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:11,327,086...11,437,799
Ensembl chr27:11,426,647...11,437,303 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G PTH parathyroid hormone involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19968565) Ensembl
MGI		 PMID:19968565 GO_REF:0000107 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967 		JBrowse link
G PTH1R parathyroid hormone 1 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11606467), (PMID:9832460) Ensembl
MGI		 PMID:9832460 PMID:11606467 GO_REF:0000107 NCBI chr20:41,905,265...41,924,712
Ensembl chr20:41,905,273...41,925,794 		JBrowse link
G PTHLH parathyroid hormone like hormone involved_in
NOT|acts_upstream_of_or_within		 IEA
ISO		 (PMID:11606467)
(PMID:19968565)		 InterPro
MGI		 PMID:11606467 PMID:19968565 GO_REF:0000002 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078 		JBrowse link
G PTN pleiotrophin acts_upstream_of_or_within ISO (PMID:12413943) MGI PMID:12413943 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814 		JBrowse link
G ROGDI rogdi atypical leucine zipper acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:38172607) MGI
Ensembl		 PMID:38172607 GO_REF:0000107 NCBI chr 6:36,618,670...36,624,533
Ensembl chr 6:36,491,561...36,624,532 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:23337931 RGD:11537369 NCBI chr 1:95,209,122...95,280,956
Ensembl chr 1:95,088,745...95,280,151 		JBrowse link
G RSPO2 R-spondin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19213727) Ensembl
MGI		 PMID:19213727 GO_REF:0000107 NCBI chr13:8,610,227...8,755,727
Ensembl chr13:8,611,952...8,754,859 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:21930712) Ensembl
MGI		 PMID:21930712 GO_REF:0000107 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G SBDS SBDS ribosome maturation factor involved_in ISO (PMID:17920346) UniProt PMID:17920346 NCBI chr 6:1,256,087...1,263,482
Ensembl chr 6:1,256,546...1,263,467 		JBrowse link
G SBNO2 strawberry notch homolog 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23980096) Ensembl
MGI		 PMID:23980096 GO_REF:0000107 NCBI chr20:57,592,901...57,640,047
Ensembl chr20:57,267,724...57,640,750 		JBrowse link
G SLC24A3 solute carrier family 24 member 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6104227|PMID:28602864) ARUK-UCL
Ensembl		 PMID:28602864 GO_REF:0000107 MGI:6104227 NCBI chr24:3,593,562...4,014,366
Ensembl chr24:3,593,513...3,784,467 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24585429)
(PMID:21788370)		 Ensembl
MGI		 PMID:21788370 PMID:24585429 GO_REF:0000107 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G SPP1 secreted phosphoprotein 1 involved_in ISO (PMID:12817751) MGI PMID:12817751 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chr28:23,966,079...24,162,775
Ensembl chr28:23,966,073...24,163,737 		JBrowse link
G TMEM38B transmembrane protein 38B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27188440) Ensembl
MGI		 PMID:27188440 GO_REF:0000107 NCBI chr11:61,511,756...61,561,987
Ensembl chr11:61,511,750...61,560,556 		JBrowse link
G WNT11 Wnt family member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19213727) Ensembl
MGI		 PMID:19213727 GO_REF:0000107 NCBI chr21:22,442,496...22,463,040
Ensembl chr21:22,446,051...22,463,173 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23686339) Ensembl
MGI		 PMID:23686339 GO_REF:0000107 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160 		JBrowse link
bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANO6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:22936354) MGI PMID:22936354 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934 		JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of ISO (PMID:21490954) MGI PMID:21490954 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691 		JBrowse link
G CCDC154 coiled-coil domain containing 154 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20121924) Ensembl
MGI		 PMID:20121924 GO_REF:0000107 NCBI chr 6:39,356,234...39,364,053
Ensembl chr 6:39,357,273...39,364,740 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:25260930)
(PMID:22359666)		 MGI PMID:22359666 PMID:25260930 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718 		JBrowse link
G IFT80 intraflagellar transport 80 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:26996322) Ensembl
MGI		 PMID:26996322 GO_REF:0000107 NCBI chr34:26,332,456...26,455,428 JBrowse link
G IGF1 insulin like growth factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G LEP leptin ISO RGD PMID:21353474 RGD:5128507 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G PHOSPHO1 phosphoethanolamine/phosphocholine phosphatase 1 acts_upstream_of_or_within ISO (PMID:21272676) MGI PMID:21272676 NCBI chr 9:25,385,313...25,392,278
Ensembl chr 9:25,385,396...25,392,242 		JBrowse link
G SNX10 sorting nexin 10 acts_upstream_of_or_within ISO (PMID:25811986) MGI PMID:25811986 NCBI chr14:39,567,701...39,642,475
Ensembl chr14:39,567,471...39,640,872 		JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein involved_in ISO
IEA		 RGD
Ensembl		 PMID:8702833 GO_REF:0000107 RGD:1626074 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716 		JBrowse link
G BCOR BCL6 corepressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:34,621,314...34,735,502
Ensembl chr  X:34,621,886...34,645,766 		JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396 PMID:25479107 PMID:30111653 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718 		JBrowse link
G FGF23 fibroblast growth factor 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766 		JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15005853) Ensembl
MGI		 PMID:15005853 GO_REF:0000107 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17181398) Ensembl
MGI		 PMID:17181398 GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G LOC480600 chemokine (C-C motif) ligand 3 involved_in ISO (PMID:21403648) UniProt PMID:21403648 NCBI chr 9:37,708,561...37,710,209
Ensembl chr 9:37,676,966...37,710,209 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433 		JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:22766095)
(PMID:12421822), (PMID:15843468)		 MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chr32:11,212,531...11,222,805
Ensembl chr32:11,212,531...11,222,805 		JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chr27:1,003,551...1,010,514
Ensembl chr27:1,003,816...1,010,264 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G SRGN serglycin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:20,230,713...20,244,952
Ensembl chr 4:20,230,743...20,244,474 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967 		JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24436304) Ensembl
MGI		 PMID:24436304 GO_REF:0000107 NCBI chr 9:45,232,910...45,239,569
Ensembl chr 9:45,232,975...45,239,130 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:3,743,257...3,818,659
Ensembl chr36:3,744,163...3,818,652 		JBrowse link
G ACVR2A activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr19:49,642,429...49,726,720
Ensembl chr19:49,641,219...49,723,420 		JBrowse link
G ACVR2B activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chr23:8,211,555...8,225,596
Ensembl chr23:8,192,483...8,218,894 		JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chr 3:17,866,459...18,351,532
Ensembl chr 3:17,866,808...18,351,532 		JBrowse link
G ADRB2 adrenoceptor beta 2 acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chr 4:60,048,502...60,050,447
Ensembl chr 4:59,941,517...60,050,298 		JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in IEA Ensembl GO_REF:0000107
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:2,170,920...2,218,765
Ensembl chr28:2,170,920...2,219,609 		JBrowse link
G ANO6 anoctamin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:8,882,691...9,067,057
Ensembl chr27:8,884,062...9,066,934 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:30,547,009...30,674,094
Ensembl chr15:30,547,015...30,616,429 		JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:21,193,685...21,198,897
Ensembl chr17:21,193,909...21,198,718 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:14749725) RGD
Ensembl
MGI		 PMID:14749725 PMID:15352071 GO_REF:0000107 RGD:9068399 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,499,898...34,582,481
Ensembl chr 4:34,517,492...34,578,923 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:17,761,555...17,978,056
Ensembl chr32:17,870,904...18,016,444 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:11,342,292...11,540,199
Ensembl chr37:11,342,384...11,533,024 		JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:62,443,285...62,446,246
Ensembl chr 6:62,443,675...62,445,994 		JBrowse link
G CD276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chr30:36,975,085...36,990,012
Ensembl chr30:36,975,085...36,988,924 		JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr 6:16,448,603...16,497,064
Ensembl chr 6:16,448,588...16,497,752 		JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,311,238...17,551,536
Ensembl chr11:17,311,226...17,551,536 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 3:62,309,128...62,318,932
Ensembl chr 3:62,303,756...62,323,896 		JBrowse link
G FZD9 frizzled class receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,782,394...6,784,565
Ensembl chr 6:6,782,774...6,784,558 		JBrowse link
G GPM6B glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:10,214,889...10,375,151
Ensembl chr  X:10,214,933...10,374,837 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,230,879...56,237,354
Ensembl chr 5:56,236,318...56,404,695 		JBrowse link
G KL klotho involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:7,154,359...7,201,744
Ensembl chr25:7,156,620...7,199,558 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852 		JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr38:16,880,411...16,936,368
Ensembl chr38:16,879,740...16,935,844 		JBrowse link
G NELL1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chr21:42,654,925...43,468,806
Ensembl chr21:42,656,339...43,468,806 		JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,508,543...14,515,657
Ensembl chr17:14,509,333...14,589,228 		JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:1,019,167...1,031,622
Ensembl chr13:1,023,879...1,031,225 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12677010), (PMID:18519738) Ensembl
MGI		 PMID:12677010 PMID:18519738 GO_REF:0000107 NCBI chr26:7,928,863...7,983,956
Ensembl chr26:7,940,985...7,983,740 		JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr 7:19,804,412...19,955,215
Ensembl chr 7:19,832,664...19,966,936 		JBrowse link
G PTH parathyroid hormone involved_in ISO
IEA		 RGD
Ensembl		 PMID:15758479 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967 		JBrowse link
G PTN pleiotrophin involved_in ISO (MGI:6294181|PMID:19442624) UniProt PMID:19442624 MGI:6294181 NCBI chr16:11,283,078...11,382,820
Ensembl chr16:11,283,077...11,382,814 		JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in ISO (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chr16:23,165,347...23,268,115
Ensembl chr16:23,200,798...23,267,775 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,004,207...32,381,399
Ensembl chr17:32,005,245...32,307,700 		JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:42,270,029...42,277,905
Ensembl chr12:42,274,000...42,277,513 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270 		JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:18,275,719...18,282,905
Ensembl chr26:18,260,923...18,282,409 		JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15728361) Ensembl
MGI		 PMID:15728361 GO_REF:0000107 NCBI chr27:5,599,905...5,605,506
Ensembl chr27:5,601,089...5,605,501 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,112,045...77,129,702
Ensembl chr 2:77,101,300...77,127,111 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,787,353...50,801,036
Ensembl chr18:50,787,353...50,801,197 		JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr17:19,914,026...20,065,141
Ensembl chr17:19,895,568...20,044,691 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:15,199,667...15,211,509
Ensembl chr24:15,200,291...15,212,217 		JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKH ANKH inorganic pyrophosphate transport regulator involved_in
acts_upstream_of_or_within		 ISO (MGI:6448251|PMID:32639996)
(PMID:10894769), (PMID:7276519)		 UniProt
MGI		 PMID:7276519 PMID:10894769 PMID:32639996 MGI:6448251 NCBI chr 4:88,149,250...88,263,926
Ensembl chr 4:88,149,257...88,272,464 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791 		JBrowse link
G BMP2K BMP2 inducible kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11500515) Ensembl
MGI		 PMID:11500515 GO_REF:0000107 NCBI chr32:3,178,554...3,293,397
Ensembl chr32:3,178,460...3,288,926 		JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21350216) Ensembl
MGI		 PMID:21350216 GO_REF:0000107 NCBI chr20:44,306,813...44,314,575
Ensembl chr20:44,306,859...44,314,625 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,825,224...1,830,845
Ensembl chr10:1,826,046...1,829,911 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20138147) Ensembl
MGI		 PMID:20138147 GO_REF:0000107 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744 		JBrowse link
G FGF23 fibroblast growth factor 23 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15579309) Ensembl
MGI		 PMID:15579309 GO_REF:0000107 NCBI chr27:40,501,655...40,511,785
Ensembl chr27:40,501,731...40,509,766 		JBrowse link
G GJA1 gap junction protein alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21346198) Ensembl
MGI		 PMID:21346198 GO_REF:0000107 NCBI chr 1:60,941,772...60,944,694
Ensembl chr 1:60,929,097...60,942,936 		JBrowse link
G GLA galactosidase alpha involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:75,311,536...75,320,391
Ensembl chr  X:75,311,536...75,320,249 		JBrowse link
G MATN1 matrilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16877353) Ensembl
MGI		 PMID:16877353 GO_REF:0000107 NCBI chr 2:70,225,642...70,234,972 JBrowse link
G MGP matrix Gla protein involved_in IEA InterPro GO_REF:0000002 NCBI chr27:31,735,301...31,738,673
Ensembl chr27:31,734,660...31,738,673 		JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,926,885...19,959,552
Ensembl chr 9:19,915,973...19,958,789 		JBrowse link
G NOTUM notum, palmitoleoyl-protein carboxylesterase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:30622831) MGI
Ensembl		 PMID:30622831 GO_REF:0000107 NCBI chr 9:344,648...350,676
Ensembl chr 9:344,020...350,368 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in ISO (MGI:3839226|PMID:19204730) UniProt PMID:19204730 MGI:3839226 NCBI chr 6:48,897,320...48,902,206
Ensembl chr 6:48,897,449...48,900,037 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107
G SGMS2 sphingomyelin synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:28,277,195...28,407,761
Ensembl chr32:28,354,116...28,403,734 		JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chr  X:41,894,623...41,907,854
Ensembl chr  X:41,893,045...41,906,403 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in IEA Ensembl GO_REF:0000107
G TXLNG taxilin gamma involved_in ISO (MGI:3587454|PMID:15911876), (MGI:5306578|PMID:19016261) UniProt PMID:15911876 PMID:19016261 MGI:3587454 MGI:5306578 NCBI chr  X:12,924,612...12,980,926
Ensembl chr  X:12,924,672...12,978,346 		JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23695662) Ensembl
MGI		 PMID:23695662 GO_REF:0000107 NCBI chr15:2,669,546...2,708,480
Ensembl chr15:2,670,326...2,709,160 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17068
    multicellular organismal process 7864
      ossification 502
        bone mineralization 138
          bone mineralization involved in bone maturation + 14
          negative regulation of bone mineralization + 19
          phosphatidylserine exposure on osteoblast involved in bone mineralization 0
          positive regulation of bone mineralization + 47
          regulation of bone mineralization + 84
Path 2
Term Annotations click to browse term
  biological_process 17068
    developmental process 6529
      anatomical structure development 6154
        tissue development 2177
          biomineral tissue development 184
            bone mineralization 138
              bone mineralization involved in bone maturation + 14
              negative regulation of bone mineralization + 19
              phosphatidylserine exposure on osteoblast involved in bone mineralization 0
              positive regulation of bone mineralization + 47
              regulation of bone mineralization + 84
paths to the root