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ONTOLOGY REPORT - ANNOTATIONS

Term:bone mineralization
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Accession:GO:0030282 term browser browse the term
Definition:The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
Synonyms:narrow_synonym: bone calcification

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show annotations for term's descendants           Sort by:
bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase acts_upstream_of_or_within ISO (PMID:14716014) MGI PMID:14716014 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Alpl alkaline phosphatase, biomineralization associated involved_in ISO (PMID:12082181)
(PMID:15920156)
(PMID:12082181), (PMID:15920156)
(MGI:2183534|PMID:10620060), (MGI:3033280|PMID:14982838), (MGI:5049900|PMID:20684022), (MGI:6827210|PMID:26457330), (MGI:6827471|PMID:11028439), (MGI:86401|PMID:9056646), (PMID:12082181)		 MGI
UniProt		 PMID:9056646 PMID:10620060 PMID:11028439 PMID:12082181 PMID:14982838 More... MGI:2183534 MGI:3033280 MGI:5049900 MGI:6827210 MGI:6827471 MGI:86401 NCBI chrNW_004955452:1,820,212...1,873,877
Ensembl chrNW_004955452:1,820,174...1,874,226 		JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator involved_in ISO (PMID:12817751) MGI PMID:12817751 NCBI chrNW_004955426:3,992,671...4,130,754
Ensembl chrNW_004955426:3,992,671...4,130,754 		JBrowse link
G Aspn asporin involved_in ISO (PMID:19589127) UniProt PMID:19589127 NCBI chrNW_004955515:5,322,074...5,345,715
Ensembl chrNW_004955515:5,321,943...5,345,894 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISO (MGI:3040115|PMID:15109498) UniProt PMID:15109498 MGI:3040115 NCBI chrNW_004955413:25,406,589...25,408,727
Ensembl chrNW_004955413:25,406,589...25,412,218 		JBrowse link
G Axin2 axin 2 acts_upstream_of_or_within ISO (PMID:19623616) MGI PMID:19623616 NCBI chrNW_004955478:4,952,551...4,982,223
Ensembl chrNW_004955478:4,952,488...4,982,225 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (PMID:19213727)
(PMID:15657444), (PMID:19213727)		 MGI PMID:15657444 PMID:19213727 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist involved_in ISO (PMID:19113921) BHF-UCL PMID:19113921 NCBI chrNW_004955434:17,738,281...17,740,823
Ensembl chrNW_004955434:17,734,495...17,740,823 		JBrowse link
G Clec3b C-type lectin domain family 3 member B involved_in ISO (PMID:7798325) UniProt PMID:7798325 NCBI chrNW_004955420:26,665,472...26,669,474 JBrowse link
G Col1a2 collagen type I alpha 2 chain acts_upstream_of_or_within ISO (PMID:22910579) MGI PMID:22910579 NCBI chrNW_004955432:11,127,961...11,164,145
Ensembl chrNW_004955432:11,128,112...11,163,302 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO (PMID:19248115) MGI PMID:19248115 NCBI chrNW_004955407:42,461,837...42,479,048
Ensembl chrNW_004955407:42,461,952...42,478,261 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 acts_upstream_of_or_within ISO (PMID:21308776) MGI PMID:21308776 NCBI chrNW_004955627:37,886...43,730
Ensembl chrNW_004955627:38,128...43,728 		JBrowse link
G Duox2 dual oxidase 2 acts_upstream_of_or_within ISO (PMID:17440044) MGI PMID:17440044 NCBI chrNW_004955409:8,270,657...8,288,201
Ensembl chrNW_004955409:8,271,164...8,287,096 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (PMID:11997520) MGI PMID:11997520 NCBI chrNW_004955424:210,867...279,267
Ensembl chrNW_004955424:226,038...280,593 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in
acts_upstream_of		 ISO (PMID:28652107)
(PMID:12082181)
(PMID:26763447)
(PMID:21930712)
(PMID:15920156)
(PMID:25368121)
(PMID:12817751)
(PMID:31666661)
(PMID:24770645)		 MGI PMID:12082181 PMID:12817751 PMID:15920156 PMID:21930712 PMID:24770645 More... NCBI chrNW_004955436:12,416,147...12,477,214
Ensembl chrNW_004955436:12,415,737...12,480,359 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO (PMID:17020410) MGI PMID:17020410 NCBI chrNW_004955555:2,355,005...2,369,599
Ensembl chrNW_004955555:2,355,005...2,369,599 		JBrowse link
G Fbxl15 F-box and leucine rich repeat protein 15 involved_in ISO PMID:21572392 UniProt PMID:21572392 RGD:8554771 NCBI chrNW_004955485:7,977,222...7,979,246
Ensembl chrNW_004955485:7,977,318...7,978,983 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO (PMID:12756187) MGI PMID:12756187 NCBI chrNW_004955551:2,321,190...2,427,000 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (MGI:4457789|PMID:20582225) BHF-UCL PMID:20582225 MGI:4457789 NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:16964445) MGI PMID:16964445 NCBI chrNW_004955452:6,840,274...6,863,460
Ensembl chrNW_004955452:6,841,802...6,863,542 		JBrowse link
G Fkrp fukutin related protein acts_upstream_of_or_within ISO (PMID:27109613), (PMID:29571322) MGI PMID:27109613 PMID:29571322 NCBI chrNW_004955574:779,672...789,621
Ensembl chrNW_004955574:786,758...788,348 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:15509771) MGI PMID:15509771 NCBI chrNW_004955469:10,297,179...10,319,180
Ensembl chrNW_004955469:10,297,179...10,319,180 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004955543:334,581...342,042
Ensembl chrNW_004955543:334,061...342,061 		JBrowse link
G Gla galactosidase alpha NOT|acts_upstream_of_or_within ISO (PMID:16697974) MGI PMID:16697974 NCBI chrNW_004955503:7,526,077...7,535,817
Ensembl chrNW_004955503:7,521,930...7,535,817 		JBrowse link
G Gpc3 glypican 3 acts_upstream_of_or_within ISO (PMID:15936336) MGI PMID:15936336 NCBI chrNW_004955473:969,627...1,431,706
Ensembl chrNW_004955473:969,800...1,431,483 		JBrowse link
G Gpnmb glycoprotein nmb ISO RGD PMID:11746512 RGD:632991 NCBI chrNW_004955410:25,554,279...25,583,368
Ensembl chrNW_004955410:25,553,973...25,582,500 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of ISO (PMID:17181398) MGI PMID:17181398 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Ibsp integrin binding sialoprotein acts_upstream_of_or_within ISO (PMID:25464126) MGI PMID:25464126 NCBI chrNW_004955474:2,074,659...2,086,289
Ensembl chrNW_004955474:2,074,659...2,086,289 		JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase acts_upstream_of_or_within ISO (PMID:23686339) MGI PMID:23686339 NCBI chrNW_004955486:6,280,838...6,289,584
Ensembl chrNW_004955486:6,280,125...6,289,584 		JBrowse link
G Ifitm5 interferon induced transmembrane protein 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:24519609)
(PMID:18442316)
(MGI:5607401|PMID:20838829)		 UniProt
MGI		 PMID:18442316 PMID:20838829 PMID:24519609 MGI:5607401 NCBI chrNW_004955476:11,745,585...11,747,006
Ensembl chrNW_004955476:11,745,585...11,747,006 		JBrowse link
G Klf10 KLF transcription factor 10 acts_upstream_of_or_within ISO (PMID:15657444) MGI PMID:15657444 NCBI chrNW_004955417:27,165,146...27,168,604
Ensembl chrNW_004955417:27,164,839...27,168,604 		JBrowse link
G Lgr4 leucine rich repeat containing G protein-coupled receptor 4 involved_in ISO (MGI:4360132|PMID:19605502) UniProt PMID:19605502 MGI:4360132 NCBI chrNW_004955476:6,611,102...6,629,294
Ensembl chrNW_004955476:6,610,103...6,629,264 		JBrowse link
G LOC102011841 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in ISO (PMID:17023519) BHF-UCL PMID:17023519 NCBI chrNW_004955458:5,472,404...5,477,001
Ensembl chrNW_004955458:5,472,404...5,477,001 		JBrowse link
G Lox lysyl oxidase acts_upstream_of_or_within ISO (PMID:19458888) MGI PMID:19458888 NCBI chrNW_004955521:178,290...193,926
Ensembl chrNW_004955521:185,792...193,926 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of ISO (PMID:11790802) MGI PMID:11790802 NCBI chrNW_004955422:19,714,161...19,730,344
Ensembl chrNW_004955422:19,714,627...19,729,855 		JBrowse link
G Mepe matrix extracellular phosphoglycoprotein acts_upstream_of ISO (PMID:12421822) MGI PMID:12421822 NCBI chrNW_004955474:2,048,883...2,064,515 JBrowse link
G Minpp1 multiple inositol-polyphosphate phosphatase 1 NOT|involved_in ISO (MGI:1888425|PMID:10938126) UniProt PMID:10938126 MGI:1888425 NCBI chrNW_004955425:5,329,968...5,359,634
Ensembl chrNW_004955425:5,330,957...5,359,551 		JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in ISO (MGI:3771509|PMID:17987127) UniProt PMID:17987127 MGI:3771509 NCBI chrNW_004955412:6,106,994...6,118,760
Ensembl chrNW_004955412:6,106,994...6,118,760 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 acts_upstream_of_or_within ISO (PMID:21406566) MGI PMID:21406566 NCBI chrNW_004955540:3,204,357...3,346,026
Ensembl chrNW_004955540:3,204,367...3,346,026 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004955458:1,541,765...1,552,323 JBrowse link
G Nfix nuclear factor I X involved_in ISO (PMID:17353270) MGI PMID:17353270 NCBI chrNW_004955415:32,055,926...32,121,611
Ensembl chrNW_004955415:32,055,375...32,117,833 		JBrowse link
G Phex phosphate regulating endopeptidase X-linked acts_upstream_of_or_within ISO (PMID:15843468) MGI PMID:15843468 NCBI chrNW_004955509:2,357,263...2,546,802
Ensembl chrNW_004955509:2,357,263...2,546,802 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 involved_in ISO (MGI:5049900|PMID:20684022), (MGI:6814708|PMID:17227223), (MGI:6827210|PMID:26457330) UniProt PMID:17227223 PMID:20684022 PMID:26457330 MGI:5049900 MGI:6814708 MGI:6827210 NCBI chrNW_004955451:12,232,465...12,240,864
Ensembl chrNW_004955451:12,234,692...12,242,721 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic acts_upstream_of_or_within ISO (PMID:21553379) MGI PMID:21553379 NCBI chrNW_004955441:9,462,530...9,471,446
Ensembl chrNW_004955441:9,462,530...9,471,446 		JBrowse link
G Prickle1 prickle planar cell polarity protein 1 involved_in ISO (PMID:23913870) MGI PMID:23913870 NCBI chrNW_004955500:1,897,899...1,990,791
Ensembl chrNW_004955500:1,897,912...1,990,875 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO PMID:18519738 MGI PMID:18519738 RGD:8554572 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Pth parathyroid hormone acts_upstream_of ISO (PMID:19968565) MGI PMID:19968565 NCBI chrNW_004955414:28,828,389...28,831,417
Ensembl chrNW_004955414:28,825,651...28,831,117 		JBrowse link
G Pth1r parathyroid hormone 1 receptor acts_upstream_of_or_within ISO (PMID:11606467), (PMID:9832460) MGI PMID:9832460 PMID:11606467 NCBI chrNW_004955420:25,274,269...25,291,984
Ensembl chrNW_004955420:25,273,431...25,296,471 		JBrowse link
G Pthlh parathyroid hormone like hormone acts_upstream_of
NOT|acts_upstream_of_or_within		 ISO (PMID:19968565)
(PMID:11606467)		 MGI PMID:11606467 PMID:19968565 NCBI chrNW_004955505:6,834,533...6,846,909
Ensembl chrNW_004955505:6,834,533...6,847,335 		JBrowse link
G Ptn pleiotrophin acts_upstream_of_or_within ISO (PMID:12413943) MGI PMID:12413943 NCBI chrNW_004955494:5,580,264...5,681,848
Ensembl chrNW_004955494:5,580,422...5,684,190 		JBrowse link
G Rogdi rogdi atypical leucine zipper acts_upstream_of_or_within ISO (PMID:38172607) MGI PMID:38172607 NCBI chrNW_004955442:12,694,197...12,700,181
Ensembl chrNW_004955442:12,694,197...12,700,181 		JBrowse link
G Ror2 receptor tyrosine kinase like orphan receptor 2 ISO RGD PMID:23337931 RGD:11537369 NCBI chrNW_004955515:313,612...554,751
Ensembl chrNW_004955515:313,604...553,774 		JBrowse link
G Rspo2 R-spondin 2 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chrNW_004955417:30,643,554...30,704,497
Ensembl chrNW_004955417:30,643,554...30,704,497 		JBrowse link
G Runx2 RUNX family transcription factor 2 acts_upstream_of ISO (PMID:21930712) MGI PMID:21930712 NCBI chrNW_004955437:10,598,145...10,885,858
Ensembl chrNW_004955437:10,598,145...10,800,560 		JBrowse link
G Sbds SBDS ribosome maturation factor involved_in ISO (PMID:17920346) UniProt PMID:17920346 NCBI chrNW_004955456:8,773,917...8,782,427 JBrowse link
G Sbno2 strawberry notch homolog 2 acts_upstream_of_or_within ISO (PMID:23980096) MGI PMID:23980096 NCBI chrNW_004955495:6,709,190...6,770,816
Ensembl chrNW_004955495:6,729,205...6,772,180 		JBrowse link
G Slc24a3 solute carrier family 24 member 3 acts_upstream_of_or_within ISO (MGI:6104227|PMID:28602864) ARUK-UCL PMID:28602864 MGI:6104227 NCBI chrNW_004955415:27,477,801...27,930,108
Ensembl chrNW_004955415:27,477,819...27,928,383 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 acts_upstream_of_or_within ISO (PMID:21788370)
(PMID:24585429)		 MGI PMID:21788370 PMID:24585429 NCBI chrNW_004955484:8,207,686...8,298,164
Ensembl chrNW_004955484:8,272,572...8,298,144 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of ISO (PMID:11371614) MGI PMID:11371614 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563 		JBrowse link
G Spp1 secreted phosphoprotein 1 involved_in ISO (PMID:12817751) MGI PMID:12817751 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chrNW_004955431:18,020,309...18,207,926
Ensembl chrNW_004955431:18,020,409...18,209,134 		JBrowse link
G Tmem38b transmembrane protein 38B acts_upstream_of_or_within ISO (PMID:27188440) MGI PMID:27188440 NCBI chrNW_004955419:20,811,931...20,844,420
Ensembl chrNW_004955419:20,812,702...20,878,599 		JBrowse link
G Wnt11 Wnt family member 11 acts_upstream_of_or_within ISO (PMID:19213727) MGI PMID:19213727 NCBI chrNW_004955414:15,674,478...15,694,758
Ensembl chrNW_004955414:15,674,940...15,694,883 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (PMID:23686339) MGI PMID:23686339 NCBI chrNW_004955537:82,724...134,609
Ensembl chrNW_004955537:81,920...134,609 		JBrowse link
bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano6 anoctamin 6 acts_upstream_of_or_within ISO (PMID:22936354) MGI PMID:22936354 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of ISO (PMID:21490954) MGI PMID:21490954 NCBI chrNW_004955469:7,786,030...7,923,739
Ensembl chrNW_004955469:7,786,154...7,923,500 		JBrowse link
G Ccdc154 coiled-coil domain containing 154 acts_upstream_of_or_within ISO (PMID:20121924) MGI PMID:20121924 NCBI chrNW_004955442:15,792,593...15,800,410
Ensembl chrNW_004955442:15,793,049...15,800,364 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:25260930)
(PMID:22359666)		 MGI PMID:22359666 PMID:25260930 NCBI chrNW_004955436:12,416,147...12,477,214
Ensembl chrNW_004955436:12,415,737...12,480,359 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO (PMID:26996322) MGI PMID:26996322 NCBI chrNW_004955448:10,808,940...10,819,655 JBrowse link
G Igf1 insulin like growth factor 1 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152 		JBrowse link
G Lep leptin ISO RGD PMID:21353474 RGD:5128507 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472 		JBrowse link
G Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 acts_upstream_of_or_within ISO (PMID:21272676) MGI PMID:21272676 NCBI chrNW_004955451:12,232,465...12,240,864
Ensembl chrNW_004955451:12,234,692...12,242,721 		JBrowse link
G Snx10 sorting nexin 10 acts_upstream_of_or_within ISO (PMID:25811986) MGI PMID:25811986 NCBI chrNW_004955410:28,137,426...28,178,814 JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahsg alpha 2-HS glycoprotein involved_in ISO (MGI:3687916|PMID:12556469) RGD
UniProt		 PMID:8702833 PMID:12556469 MGI:3687916 RGD:1626074 NCBI chrNW_004955420:21,071,111...21,078,397
Ensembl chrNW_004955420:21,069,681...21,078,298 		JBrowse link
G Bcor BCL6 corepressor involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chrNW_004955566:1,412,540...1,510,339
Ensembl chrNW_004955566:1,412,540...1,457,329 		JBrowse link
G Ecm1 extracellular matrix protein 1 involved_in ISO (PMID:11165938) UniProt PMID:11165938 NCBI chrNW_004955413:293,295...299,293
Ensembl chrNW_004955413:290,363...299,130 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396 PMID:25479107 PMID:30111653 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chrNW_004955436:12,416,147...12,477,214
Ensembl chrNW_004955436:12,415,737...12,480,359 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:18282132) UniProt PMID:18282132 NCBI chrNW_004955413:2,182,459...2,192,279
Ensembl chrNW_004955413:2,182,459...2,192,279 		JBrowse link
G Gata1 GATA binding protein 1 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004955543:334,581...342,042
Ensembl chrNW_004955543:334,061...342,061 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004955416:1,812,725...1,825,528
Ensembl chrNW_004955416:1,812,676...1,826,271 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within ISO (PMID:17181398) MGI PMID:17181398 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO (PMID:11790802) MGI PMID:11790802 NCBI chrNW_004955422:19,714,161...19,730,344
Ensembl chrNW_004955422:19,714,627...19,729,855 		JBrowse link
G Mepe matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:22766095)
(PMID:12421822), (PMID:15843468)		 MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chrNW_004955474:2,048,883...2,064,515 JBrowse link
G Nfe2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chrNW_004955458:1,541,765...1,552,323 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO (MGI:3713957|PMID:17537919) UniProt PMID:17537919 MGI:3713957 NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:11371614) MGI PMID:11371614 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563 		JBrowse link
G Srgn serglycin involved_in ISO (PMID:16870619) UniProt PMID:16870619 NCBI chrNW_004955437:21,954,837...21,966,552
Ensembl chrNW_004955437:21,951,732...21,965,581 		JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chrNW_004955559:1,539,036...1,581,800
Ensembl chrNW_004955559:1,546,365...1,581,712 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chrNW_004955416:1,812,725...1,825,528
Ensembl chrNW_004955416:1,812,676...1,826,271 		JBrowse link
G LOC102011120 filamin-interacting protein FAM101A acts_upstream_of_or_within ISO (PMID:24436304) MGI PMID:24436304 NCBI chrNW_004955482:5,034,075...5,044,162
Ensembl chrNW_004955482:5,033,914...5,042,790 		JBrowse link
G Pth parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chrNW_004955414:28,828,389...28,831,417
Ensembl chrNW_004955414:28,825,651...28,831,117 		JBrowse link
G Rflnb refilin B acts_upstream_of_or_within ISO (PMID:24436304) MGI PMID:24436304 NCBI chrNW_004955481:2,102,576...2,107,947
Ensembl chrNW_004955481:2,102,586...2,107,967 		JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694 		JBrowse link
G Acvr2a activin A receptor type 2A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955440:13,849,926...13,931,374
Ensembl chrNW_004955440:13,849,926...13,931,374 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955427:25,438,652...25,467,360
Ensembl chrNW_004955427:25,438,652...25,467,360 		JBrowse link
G Adgrv1 adhesion G protein-coupled receptor V1 involved_in ISO (MGI:6211994|PMID:22419726) UniProt PMID:22419726 MGI:6211994 NCBI chrNW_004955418:20,603,323...21,039,891 JBrowse link
G Adrb2 adrenoceptor beta 2 acts_upstream_of_or_within ISO (PMID:15724149) MGI PMID:15724149 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in ISO (MGI:6393219|PMID:24906289) UniProt PMID:24906289 MGI:6393219 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Ano6 anoctamin 6 involved_in ISO (PMID:25589784)
(MGI:5634871|PMID:25589784)		 UniProt PMID:25589784 MGI:5634871 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 involved_in ISO (MGI:5780494|PMID:26392310) UniProt PMID:26392310 MGI:5780494 NCBI chrNW_004955405:26,872,379...26,932,270
Ensembl chrNW_004955405:26,872,379...26,932,703 		JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004955469:9,194,656...9,203,292 JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:18436533), (PMID:20576608)
(MGI:5009350|PMID:20675382)		 BHF-UCL PMID:18436533 PMID:20576608 PMID:20675382 MGI:5009350 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in		 ISO (PMID:14749725)
(PMID:14749725), (PMID:18436533)		 RGD
MGI		 PMID:14749725 PMID:15352071 PMID:18436533 RGD:9068399 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955405:5,408,171...5,784,930
Ensembl chrNW_004955405:5,700,162...5,787,957 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:18436533) BHF-UCL PMID:18436533 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G Ccn1 cellular communication network factor 1 involved_in ISO (PMID:20675382) BHF-UCL PMID:20675382 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Cd276 CD276 molecule acts_upstream_of_or_within ISO (PMID:15317945) MGI PMID:15317945 NCBI chrNW_004955450:3,884,437...3,896,416 JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chrNW_004955415:4,434,486...4,462,505
Ensembl chrNW_004955415:4,434,453...4,461,751 		JBrowse link
G Fam20c FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chrNW_004955460:8,142,325...8,192,044
Ensembl chrNW_004955460:8,143,824...8,193,825 		JBrowse link
G Fbn2 fibrillin 2 involved_in ISO (MGI:4836762|PMID:20855508) BHF-UCL PMID:20855508 MGI:4836762 NCBI chrNW_004955415:1,307,553...1,535,435
Ensembl chrNW_004955415:1,309,077...1,537,052 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chrNW_004955514:1,030,244...1,038,590
Ensembl chrNW_004955514:1,025,600...1,038,590 		JBrowse link
G Fzd9 frizzled class receptor 9 involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004955456:14,245,994...14,247,551
Ensembl chrNW_004955456:14,246,324...14,247,550 		JBrowse link
G Gpm6b glycoprotein M6B involved_in ISO (PMID:21638316) UniProt PMID:21638316 NCBI chrNW_004955519:4,287,203...4,432,188
Ensembl chrNW_004955519:4,287,026...4,432,188 		JBrowse link
G Isg15 ISG15 ubiquitin like modifier involved_in ISO (MGI:4943600|PMID:21402791) UniProt PMID:21402791 MGI:4943600 NCBI chrNW_004955486:9,706,878...9,707,876
Ensembl chrNW_004955486:9,706,703...9,707,949 		JBrowse link
G Kl klotho involved_in ISO (PMID:12110410) UniProt PMID:12110410 NCBI chrNW_004955431:12,782,913...12,833,215
Ensembl chrNW_004955431:12,782,846...12,833,215 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:5285459|PMID:21652706) UniProt PMID:21652706 MGI:5285459 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chrNW_004955520:1,853,145...1,890,338
Ensembl chrNW_004955520:1,850,942...1,890,390 		JBrowse link
G Nell1 neural EGFL like 1 involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chrNW_004955476:1,445,234...2,236,954
Ensembl chrNW_004955476:1,445,353...2,233,146 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 involved_in ISO (MGI:4950000|PMID:21262216) BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004955469:1,954,470...1,961,344
Ensembl chrNW_004955469:1,953,370...1,961,390 		JBrowse link
G Osr2 odd-skipped related transciption factor 2 involved_in ISO (MGI:4950000|PMID:21262216) BHF-UCL PMID:21262216 MGI:4950000 NCBI chrNW_004955417:14,502,450...14,510,015
Ensembl chrNW_004955417:14,502,451...14,510,160 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194) UniProt PMID:19097194 MGI:3813934 NCBI chrNW_004955441:9,462,530...9,471,446
Ensembl chrNW_004955441:9,462,530...9,471,446 		JBrowse link
G Pla2g4a phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chrNW_004955406:25,257,361...25,392,079
Ensembl chrNW_004955406:25,257,355...25,394,206 		JBrowse link
G Pth parathyroid hormone involved_in ISO (PMID:17696759) RGD
UniProt		 PMID:15758479 PMID:17696759 PMID:22445539 RGD:7207452 RGD:7242906 NCBI chrNW_004955414:28,828,389...28,831,417
Ensembl chrNW_004955414:28,825,651...28,831,117 		JBrowse link
G Ptn pleiotrophin involved_in ISO (MGI:6294181|PMID:19442624) UniProt PMID:19442624 MGI:6294181 NCBI chrNW_004955494:5,580,264...5,681,848
Ensembl chrNW_004955494:5,580,422...5,684,190 		JBrowse link
G Slc20a2 solute carrier family 20 member 2 involved_in ISO (MGI:6342320|PMID:30721528) UniProt PMID:30721528 MGI:6342320 NCBI chrNW_004955536:392,341...496,616
Ensembl chrNW_004955536:392,525...495,265 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 involved_in ISO (PMID:25589784) UniProt PMID:25589784 NCBI chrNW_004955441:7,653,107...8,037,784
Ensembl chrNW_004955441:7,656,031...7,957,640 		JBrowse link
G Smad3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A involved_in ISO (MGI:6717031|PMID:33882302) UniProt PMID:33882302 MGI:6717031 NCBI chrNW_004955411:9,695,149...9,701,463
Ensembl chrNW_004955411:9,699,011...9,701,507 		JBrowse link
G Tfap2a transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chrNW_004955465:3,877,896...3,900,259
Ensembl chrNW_004955465:3,882,549...3,898,929 		JBrowse link
G Tmem119 transmembrane protein 119 involved_in ISO (PMID:20025746)
(MGI:4418582|PMID:20025746), (MGI:5700277|PMID:26207632)		 UniProt PMID:20025746 PMID:26207632 MGI:4418582 MGI:5700277 NCBI chrNW_004955455:9,856,443...9,863,100
Ensembl chrNW_004955455:9,856,443...9,863,100 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:15728361) MGI PMID:15728361 NCBI chrNW_004955500:7,782,782...7,800,281
Ensembl chrNW_004955500:7,782,782...7,788,309 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:17720811) BHF-UCL PMID:17720811 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5291888|PMID:21784188) UniProt PMID:21784188 MGI:5291888 NCBI chrNW_004955422:18,799,372...18,812,458
Ensembl chrNW_004955422:18,799,372...18,812,711 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chrNW_004955469:7,786,030...7,923,739
Ensembl chrNW_004955469:7,786,154...7,923,500 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:16433617) BHF-UCL PMID:16433617 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankh ANKH inorganic pyrophosphate transport regulator involved_in
acts_upstream_of_or_within		 ISO (MGI:6448251|PMID:32639996)
(PMID:10894769), (PMID:7276519)		 UniProt
MGI		 PMID:7276519 PMID:10894769 PMID:32639996 MGI:6448251 NCBI chrNW_004955426:3,992,671...4,130,754
Ensembl chrNW_004955426:3,992,671...4,130,754 		JBrowse link
G Bmp2k BMP2 inducible kinase acts_upstream_of_or_within ISO (PMID:11500515) MGI PMID:11500515 NCBI chrNW_004955433:3,207,512...3,327,688
Ensembl chrNW_004955433:3,207,512...3,327,688 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (PMID:20564243) UniProt PMID:20564243 NCBI chrNW_004955462:13,578,638...13,644,834
Ensembl chrNW_004955462:13,584,724...13,642,968 		JBrowse link
G Ecm1 extracellular matrix protein 1 acts_upstream_of_or_within ISO (PMID:20138147) MGI PMID:20138147 NCBI chrNW_004955413:293,295...299,293
Ensembl chrNW_004955413:290,363...299,130 		JBrowse link
G Fgf23 fibroblast growth factor 23 acts_upstream_of_or_within ISO (PMID:15579309) MGI PMID:15579309 NCBI chrNW_004955413:2,182,459...2,192,279
Ensembl chrNW_004955413:2,182,459...2,192,279 		JBrowse link
G Gja1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:21346198) MGI PMID:21346198 NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095 		JBrowse link
G LOC102011841 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in ISO (PMID:9415400) BHF-UCL PMID:9415400 NCBI chrNW_004955458:5,472,404...5,477,001
Ensembl chrNW_004955458:5,472,404...5,477,001 		JBrowse link
G Matn1 matrilin 1 acts_upstream_of_or_within ISO (PMID:16877353) MGI PMID:16877353 NCBI chrNW_004955452:9,317,726...9,325,803
Ensembl chrNW_004955452:9,317,716...9,325,812 		JBrowse link
G Nbr1 NBR1 autophagy cargo receptor involved_in ISO (MGI:4818844|PMID:20616007) BHF-UCL PMID:20616007 MGI:4818844 NCBI chrNW_004955451:16,871,091...16,896,090
Ensembl chrNW_004955451:16,871,586...16,895,179 		JBrowse link
G Notum notum, palmitoleoyl-protein carboxylesterase acts_upstream_of_or_within ISO (PMID:30622831) MGI PMID:30622831 NCBI chrNW_004955506:1,203,309...1,212,938
Ensembl chrNW_004955506:1,203,309...1,212,966 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 involved_in ISO (MGI:3839226|PMID:19204730) UniProt PMID:19204730 MGI:3839226 NCBI chrNW_004955435:5,880,266...5,882,823
Ensembl chrNW_004955435:5,880,288...5,881,436 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in ISO (PMID:30779713) UniProt PMID:30779713 NCBI chrNW_004955496:1,909,347...1,955,004
Ensembl chrNW_004955496:1,905,517...1,947,009 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chrNW_004955543:258,479...271,128
Ensembl chrNW_004955543:258,479...272,473 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:19597909) BHF-UCL PMID:19597909 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
G Txlng taxilin gamma involved_in ISO (MGI:3587454|PMID:15911876), (MGI:5306578|PMID:19016261) UniProt PMID:15911876 PMID:19016261 MGI:3587454 MGI:5306578 NCBI chrNW_004955519:1,484,782...1,536,278
Ensembl chrNW_004955519:1,484,782...1,536,659 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chrNW_004955537:82,724...134,609
Ensembl chrNW_004955537:81,920...134,609 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12482
    multicellular organismal process 6203
      ossification 411
        bone mineralization 131
          bone mineralization involved in bone maturation + 15
          negative regulation of bone mineralization + 18
          phosphatidylserine exposure on osteoblast involved in bone mineralization 0
          positive regulation of bone mineralization + 46
          regulation of bone mineralization + 77
Path 2
Term Annotations click to browse term
  biological_process 12482
    developmental process 5885
      anatomical structure development 5569
        tissue development 1981
          biomineral tissue development 173
            bone mineralization 131
              bone mineralization involved in bone maturation + 15
              negative regulation of bone mineralization + 18
              phosphatidylserine exposure on osteoblast involved in bone mineralization 0
              positive regulation of bone mineralization + 46
              regulation of bone mineralization + 77
paths to the root