ONTOLOGY REPORT - ANNOTATIONS |
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Term: | bone mineralization |
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Accession: | GO:0030282
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browse the term
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Definition: | The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. |
Synonyms: | narrow_synonym: | bone calcification |
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ALOX15 |
arachidonate 15-lipoxygenase |
acts_upstream_of_or_within |
ISO |
(PMID:14716014) |
MGI |
PMID:14716014 |
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NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669
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ALPL |
alkaline phosphatase, biomineralization associated |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:20,702,509...20,772,301
Ensembl chr 1:21,667,732...21,736,688
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ANKH |
ANKH inorganic pyrophosphate transport regulator |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 5:15,014,019...15,175,467
Ensembl chr 5:14,855,914...14,917,729
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ASGR2 |
asialoglycoprotein receptor 2 |
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ISO |
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RGD |
PMID:19841953 |
RGD:2316850 |
NCBI chr17:7,131,490...7,145,110
Ensembl chr17:7,119,432...7,133,520
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ASPN |
asporin |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 9:63,579,188...63,605,811
Ensembl chr 9:91,651,629...91,677,969
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ATF4 |
activating transcription factor 4 |
involved_in |
ISO |
(MGI:3040115|PMID:15109498) |
UniProt |
PMID:15109498 |
MGI:3040115 |
NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
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AXIN2 |
axin 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19623616) |
Ensembl MGI |
PMID:19623616 |
GO_REF:0000107 |
NCBI chr17:59,476,336...59,509,358
Ensembl chr17:64,688,416...64,720,086
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BMP2 |
bone morphogenetic protein 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19213727) (PMID:15657444), (PMID:19213727) |
Ensembl MGI |
PMID:15657444 PMID:19213727 |
GO_REF:0000107 |
NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
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CER1 |
cerberus 1, DAN family BMP antagonist |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 9:14,552,062...14,559,632
Ensembl chr 9:15,063,766...15,066,776
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CLEC3B |
C-type lectin domain family 3 member B |
involved_in |
IEA |
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Ensembl TreeGrafter |
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GO_REF:0000107 GO_REF:0000118 |
NCBI chr 3:44,927,098...44,936,847
Ensembl chr 3:46,038,115...46,047,927
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COL1A2 |
collagen type I alpha 2 chain |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:22910579) |
Ensembl MGI |
PMID:22910579 |
GO_REF:0000107 |
NCBI chr 7:86,344,657...86,381,282
Ensembl chr 7:99,935,185...99,971,803
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COL6A1 |
collagen type VI alpha 1 chain |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19248115) |
Ensembl MGI |
PMID:19248115 |
GO_REF:0000107 |
NCBI chr21:32,322,185...32,346,850
Ensembl chr21:45,584,096...45,607,240
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COMP |
cartilage oligomeric matrix protein |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:27151399) |
Ensembl MGI |
PMID:27151399 |
GO_REF:0000107 |
NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008
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CST5 |
cystatin D |
involved_in |
ISO |
(PMID:16680148) |
MGI |
PMID:16680148 |
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NCBI chr20:23,824,663...23,828,483
Ensembl chr20:24,178,197...24,182,016
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CYP27B1 |
cytochrome P450 family 27 subfamily B member 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
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DLK1 |
delta like non-canonical Notch ligand 1 |
acts_upstream_of_or_within |
ISO |
(PMID:21308776) |
MGI |
PMID:21308776 |
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NCBI chr14:81,348,380...81,356,607
Ensembl chr14:100,654,965...100,668,019
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DUOX2 |
dual oxidase 2 |
acts_upstream_of_or_within |
ISO |
(PMID:17440044) |
MGI |
PMID:17440044 |
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NCBI chr15:24,040,513...24,061,758
Ensembl chr15:42,395,135...42,414,281
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EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
acts_upstream_of_or_within |
ISO |
(PMID:11997520) |
MGI |
PMID:11997520 |
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NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
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ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
involved_in acts_upstream_of |
IEA ISO |
(PMID:21930712) |
Ensembl MGI |
PMID:21930712 |
GO_REF:0000107 |
NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
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ERCC2 |
ERCC excision repair 2, TFIIH core complex helicase subunit |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:17020410) |
Ensembl MGI |
PMID:17020410 |
GO_REF:0000107 |
NCBI chr19:42,298,927...42,319,816
Ensembl chr19:50,897,004...50,915,819
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FBXL15 |
F-box and leucine rich repeat protein 15 |
involved_in |
ISO |
PMID:21572392 |
UniProt |
PMID:21572392 |
RGD:8554771 |
NCBI chr10:99,022,732...99,026,623
Ensembl chr10:102,485,732...102,492,301
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FGFR2 |
fibroblast growth factor receptor 2 |
acts_upstream_of_or_within |
ISO |
(PMID:12756187) |
MGI |
PMID:12756187 |
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NCBI chr10:118,055,854...118,175,440
Ensembl chr10:121,469,735...121,588,815
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FGFR3 |
fibroblast growth factor receptor 3 |
involved_in |
ISO |
(MGI:4457789|PMID:20582225) |
BHF-UCL |
PMID:20582225 |
MGI:4457789 |
NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692
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FGR |
FGR proto-oncogene, Src family tyrosine kinase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:16964445) |
Ensembl MGI |
PMID:16964445 |
GO_REF:0000107 |
NCBI chr 1:26,872,781...26,895,751
Ensembl chr 1:27,918,758...27,941,678
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FKRP |
fukutin related protein |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:27109613), (PMID:29571322) |
Ensembl MGI |
PMID:27109613 PMID:29571322 |
GO_REF:0000107 |
NCBI chr19:43,738,339...43,748,250
Ensembl chr19:52,273,546...52,276,341
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FOSL2 |
FOS like 2, AP-1 transcription factor subunit |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15509771) |
Ensembl MGI |
PMID:15509771 |
GO_REF:0000107 |
NCBI chr2A:28,392,328...28,416,838
Ensembl chr2A:28,485,613...28,498,397
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GATA1 |
GATA binding protein 1 |
involved_in acts_upstream_of |
IEA ISO |
(PMID:15005853) |
Ensembl MGI |
PMID:15005853 |
GO_REF:0000107 |
NCBI chr X:41,088,724...41,092,190
Ensembl chr X:48,945,394...48,953,126
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GLA |
galactosidase alpha |
NOT|acts_upstream_of_or_within |
ISO |
(PMID:16697974) |
MGI |
PMID:16697974 |
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NCBI chr X:90,600,412...90,610,594
Ensembl chr X:100,732,311...100,742,280
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GPC3 |
glypican 3 |
acts_upstream_of_or_within |
ISO |
(PMID:15936336) |
MGI |
PMID:15936336 |
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NCBI chr X:122,677,072...123,131,511
Ensembl chr X:132,979,612...133,432,441
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GPNMB |
glycoprotein nmb |
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ISO |
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RGD |
PMID:11746512 |
RGD:632991 |
NCBI chr 7:23,931,220...23,959,687
Ensembl chr 7:23,539,928...23,568,624
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HIF1A |
hypoxia inducible factor 1 subunit alpha |
involved_in acts_upstream_of |
IEA ISO |
(PMID:17181398) |
Ensembl MGI |
PMID:17181398 |
GO_REF:0000107 |
NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
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IBSP |
integrin binding sialoprotein |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:25464126) |
Ensembl TreeGrafter MGI |
PMID:25464126 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr 4:80,061,960...80,105,560
Ensembl chr 4:90,817,072...90,830,021
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ICMT |
isoprenylcysteine carboxyl methyltransferase |
acts_upstream_of_or_within |
ISO |
(PMID:23686339) |
MGI |
PMID:23686339 |
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NCBI chr 1:4,987,384...5,002,213
Ensembl chr 1:6,246,570...6,258,746
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IFITM5 |
interferon induced transmembrane protein 5 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:18442316) |
Ensembl TreeGrafter MGI |
PMID:18442316 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr11:294,184...295,525
Ensembl chr11:338,216...339,557 Ensembl chr11:338,216...339,557
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KLF10 |
KLF transcription factor 10 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15657444) |
Ensembl MGI |
PMID:15657444 |
GO_REF:0000107 |
NCBI chr 8:99,302,943...99,310,099
Ensembl chr 8:101,462,915...101,469,982
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LGR4 |
leucine rich repeat containing G protein-coupled receptor 4 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr11:27,330,279...27,437,201
Ensembl chr11:27,229,963...27,291,571
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LOC100992172 |
SBDS ribosome maturation factor |
involved_in |
ISO |
(PMID:17920346) |
UniProt |
PMID:17920346 |
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NCBI chr 7:59,090,343...59,098,332
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LOX |
lysyl oxidase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19458888) |
Ensembl MGI |
PMID:19458888 |
GO_REF:0000107 |
NCBI chr 5:117,450,833...117,464,957
Ensembl chr 5:123,234,662...123,248,717
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LTBP3 |
latent transforming growth factor beta binding protein 3 |
involved_in acts_upstream_of |
IEA ISO |
(PMID:11790802) |
Ensembl MGI |
PMID:11790802 |
GO_REF:0000107 |
NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
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MEPE |
matrix extracellular phosphoglycoprotein |
acts_upstream_of |
ISO |
(PMID:12421822) |
MGI |
PMID:12421822 |
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NCBI chr 4:80,125,612...80,139,539
Ensembl chr 4:90,838,938...90,864,332
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MINPP1 |
multiple inositol-polyphosphate phosphatase 1 |
NOT|involved_in |
ISO |
(MGI:1888425|PMID:10938126) |
UniProt |
PMID:10938126 |
MGI:1888425 |
NCBI chr10:84,230,676...84,280,042
Ensembl chr10:87,737,649...87,787,130
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MMP13 |
matrix metallopeptidase 13 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679
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MTSS1 |
MTSS I-BAR domain containing 1 |
acts_upstream_of_or_within |
ISO |
(PMID:21406566) |
MGI |
PMID:21406566 |
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NCBI chr 8:121,235,545...121,413,037
Ensembl chr 8:123,987,577...124,032,339
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NFE2 |
nuclear factor, erythroid 2 |
acts_upstream_of |
ISO |
(PMID:15005853) |
MGI |
PMID:15005853 |
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NCBI chr12:34,442,913...34,452,016
Ensembl chr12:35,168,173...35,177,253
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NFIX |
nuclear factor I X |
involved_in |
ISO |
(PMID:17353270) |
MGI |
PMID:17353270 |
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NCBI chr19:12,557,020...12,660,316
Ensembl chr19:13,327,690...13,402,406
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PHEX |
phosphate regulating endopeptidase X-linked |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15843468) |
Ensembl MGI |
PMID:15843468 |
GO_REF:0000107 |
NCBI chr X:14,663,847...14,859,294
Ensembl chr X:22,017,681...22,232,501
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PHOSPHO1 |
phosphoethanolamine/phosphocholine phosphatase 1 |
involved_in |
ISO |
(MGI:5049900|PMID:20684022), (MGI:6814708|PMID:17227223), (MGI:6827210|PMID:26457330) |
UniProt |
PMID:17227223 PMID:20684022 PMID:26457330 |
MGI:5049900 MGI:6814708 MGI:6827210 |
NCBI chr17:8,373,032...8,381,410
Ensembl chr17:8,357,513...8,364,416
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PKDCC |
protein kinase domain containing, cytoplasmic |
acts_upstream_of_or_within |
ISO |
(PMID:21553379) |
MGI |
PMID:21553379 |
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NCBI chr2A:42,146,153...42,156,652
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PRICKLE1 |
prickle planar cell polarity protein 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr12:46,127,673...46,262,333
Ensembl chr12:47,100,393...47,126,102
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PTGS2 |
prostaglandin-endoperoxide synthase 2 |
acts_upstream_of_or_within |
ISO |
PMID:18519738 |
MGI |
PMID:18519738 |
RGD:8554572 |
NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519
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PTH |
parathyroid hormone |
involved_in acts_upstream_of |
IEA ISO |
(PMID:19968565) |
Ensembl MGI |
PMID:19968565 |
GO_REF:0000107 |
NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
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PTH1R |
parathyroid hormone 1 receptor |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:11606467), (PMID:9832460) |
Ensembl MGI |
PMID:9832460 PMID:11606467 |
GO_REF:0000107 |
NCBI chr 3:46,777,945...46,804,039
Ensembl chr 3:47,894,901...47,905,431
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PTHLH |
parathyroid hormone like hormone |
involved_in acts_upstream_of NOT|acts_upstream_of_or_within |
IEA ISO |
(PMID:19968565) (PMID:11606467) |
InterPro MGI |
PMID:11606467 PMID:19968565 |
GO_REF:0000002 |
NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
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PTN |
pleiotrophin |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:12413943) |
Ensembl MGI |
PMID:12413943 |
GO_REF:0000107 |
NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
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ROGDI |
rogdi atypical leucine zipper |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:38172607) |
MGI Ensembl |
PMID:38172607 |
GO_REF:0000107 |
NCBI chr16:3,721,063...3,727,056
Ensembl chr16:4,887,051...4,892,607
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ROR2 |
receptor tyrosine kinase like orphan receptor 2 |
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ISO |
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RGD |
PMID:23337931 |
RGD:11537369 |
NCBI chr 9:62,782,183...63,005,626
Ensembl chr 9:90,851,983...90,965,084
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RSPO2 |
R-spondin 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19213727) |
Ensembl MGI |
PMID:19213727 |
GO_REF:0000107 |
NCBI chr 8:104,535,751...104,721,463
Ensembl chr 8:106,685,116...106,870,494
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RUNX2 |
RUNX family transcription factor 2 |
involved_in acts_upstream_of |
IEA ISO |
(PMID:21930712) |
Ensembl MGI |
PMID:21930712 |
GO_REF:0000107 |
NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
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SBNO2 |
strawberry notch homolog 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:23980096) |
Ensembl MGI |
PMID:23980096 |
GO_REF:0000107 |
NCBI chr19:3,032...20,063
Ensembl chr19:1,086,968...1,136,272
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SLC24A3 |
solute carrier family 24 member 3 |
acts_upstream_of_or_within involved_in |
ISO IEA |
(MGI:6104227|PMID:28602864) |
ARUK-UCL Ensembl |
PMID:28602864 |
GO_REF:0000107 MGI:6104227 |
NCBI chr20:19,168,820...19,680,706
Ensembl chr20:19,137,938...19,646,475
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SMPD3 |
sphingomyelin phosphodiesterase 3 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:24585429) (PMID:21788370) |
Ensembl MGI |
PMID:21788370 PMID:24585429 |
GO_REF:0000107 |
NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871
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SOX9 |
SRY-box transcription factor 9 |
acts_upstream_of |
ISO |
(PMID:11371614) |
MGI |
PMID:11371614 |
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NCBI chr17:66,028,737...66,034,122
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SPP1 |
secreted phosphoprotein 1 |
involved_in |
ISO |
(PMID:12817751) |
MGI |
PMID:12817751 |
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NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935
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TCF7L2 |
transcription factor 7 like 2 |
acts_upstream_of_or_within |
ISO |
(PMID:19213727) |
MGI |
PMID:19213727 |
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NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281
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TMEM38B |
transmembrane protein 38B |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:27188440) |
Ensembl MGI |
PMID:27188440 |
GO_REF:0000107 |
NCBI chr 9:76,854,177...76,938,334
Ensembl chr 9:104,980,935...105,128,988
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WNT11 |
Wnt family member 11 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:19213727) |
Ensembl MGI |
PMID:19213727 |
GO_REF:0000107 |
NCBI chr11:71,239,781...71,263,915
Ensembl chr11:74,540,169...74,560,024
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ZMPSTE24 |
zinc metallopeptidase STE24 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:23686339) |
Ensembl MGI |
PMID:23686339 |
GO_REF:0000107 |
NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
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ANO6 |
anoctamin 6 |
acts_upstream_of_or_within |
ISO |
(PMID:22936354) |
MGI |
PMID:22936354 |
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NCBI chr12:43,295,928...43,512,073
Ensembl chr12:44,164,375...44,303,259
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ASXL2 |
ASXL transcriptional regulator 2 |
acts_upstream_of |
ISO |
(PMID:21490954) |
MGI |
PMID:21490954 |
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NCBI chr2A:25,730,155...25,880,089
Ensembl chr2A:25,832,527...25,973,659
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CCDC154 |
coiled-coil domain containing 154 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:20121924) |
Ensembl TreeGrafter MGI |
PMID:20121924 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr16:54,158...64,522
Ensembl chr16:1,488,750...1,498,293
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ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
involved_in |
ISO |
(PMID:22359666) (PMID:25260930) |
MGI |
PMID:22359666 PMID:25260930 |
|
NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
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|
G |
IFT80 |
intraflagellar transport 80 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:26996322) |
Ensembl MGI |
PMID:26996322 |
GO_REF:0000107 |
NCBI chr 3:157,279,076...157,421,478
Ensembl chr 3:165,329,056...165,454,905
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|
G |
IGF1 |
insulin like growth factor 1 |
involved_in |
ISO |
(PMID:16433617) |
BHF-UCL |
PMID:16433617 |
|
NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177
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G |
LEP |
leptin |
|
ISO |
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RGD |
PMID:21353474 |
RGD:5128507 |
NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519
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|
G |
PHOSPHO1 |
phosphoethanolamine/phosphocholine phosphatase 1 |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:21272676) |
MGI TreeGrafter |
PMID:21272676 |
GO_REF:0000118 |
NCBI chr17:8,373,032...8,381,410
Ensembl chr17:8,357,513...8,364,416
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|
G |
SNX10 |
sorting nexin 10 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:25811986) |
Ensembl MGI |
PMID:25811986 |
GO_REF:0000107 |
NCBI chr 7:26,935,357...27,017,461
Ensembl chr 7:26,537,189...26,620,720
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|
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G |
AHSG |
alpha 2-HS glycoprotein |
involved_in |
ISO IEA |
|
RGD Ensembl |
PMID:8702833 |
GO_REF:0000107 RGD:1626074 |
NCBI chr 3:183,644,223...183,652,620
Ensembl chr 3:192,110,770...192,119,915
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G |
BCOR |
BCL6 corepressor |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr X:32,497,931...32,624,307
Ensembl chr X:40,202,235...40,249,986
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G |
CCR1 |
C-C motif chemokine receptor 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755
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G |
ECM1 |
extracellular matrix protein 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 1:125,853,337...125,858,904
Ensembl chr 1:129,502,041...129,507,819
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|
G |
ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
involved_in |
ISO |
(MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) |
UniProt |
PMID:22510396 PMID:25479107 PMID:30111653 |
MGI:5607146 MGI:6220772 MGI:6294341 |
NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
|
|
G |
FGF23 |
fibroblast growth factor 23 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000
|
|
G |
GATA1 |
GATA binding protein 1 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15005853) |
Ensembl MGI |
PMID:15005853 |
GO_REF:0000107 |
NCBI chr X:41,088,724...41,092,190
Ensembl chr X:48,945,394...48,953,126
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|
G |
GREM1 |
gremlin 1, DAN family BMP antagonist |
involved_in |
ISO |
(PMID:15539560) |
BHF-UCL |
PMID:15539560 |
|
NCBI chr15:11,213,870...11,230,619
|
|
G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:17181398) |
Ensembl MGI |
PMID:17181398 |
GO_REF:0000107 |
NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
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|
G |
LOC100992309 |
C-C motif chemokine 3 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr17:20,704,738...20,706,641
Ensembl chr17:21,000,709...21,002,610
|
|
G |
LTBP3 |
latent transforming growth factor beta binding protein 3 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:11790802) |
Ensembl MGI |
PMID:11790802 |
GO_REF:0000107 |
NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
|
|
G |
MEPE |
matrix extracellular phosphoglycoprotein |
acts_upstream_of_or_within |
ISO |
(PMID:12421822), (PMID:15843468) (PMID:22766095) |
MGI |
PMID:12421822 PMID:15843468 PMID:22766095 |
|
NCBI chr 4:80,125,612...80,139,539
Ensembl chr 4:90,838,938...90,864,332
|
|
G |
NFE2 |
nuclear factor, erythroid 2 |
acts_upstream_of_or_within |
ISO |
(PMID:15005853) |
MGI |
PMID:15005853 |
|
NCBI chr12:34,442,913...34,452,016
Ensembl chr12:35,168,173...35,177,253
|
|
G |
PTK2B |
protein tyrosine kinase 2 beta |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
|
|
G |
SOX9 |
SRY-box transcription factor 9 |
acts_upstream_of_or_within |
ISO |
(PMID:11371614) |
MGI |
PMID:11371614 |
|
NCBI chr17:66,028,737...66,034,122
|
|
G |
SRGN |
serglycin |
involved_in |
IEA |
|
Ensembl TreeGrafter |
|
GO_REF:0000107 GO_REF:0000118 |
NCBI chr10:65,554,873...65,572,108
Ensembl chr10:68,089,392...68,106,250
|
|
G |
TRPM4 |
transient receptor potential cation channel subfamily M member 4 |
|
ISO |
|
RGD |
PMID:23081848 |
RGD:10003033 |
NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464
|
|
|
G |
GREM1 |
gremlin 1, DAN family BMP antagonist |
involved_in |
ISO |
(PMID:15539560) |
BHF-UCL |
PMID:15539560 |
|
NCBI chr15:11,213,870...11,230,619
|
|
G |
PTH |
parathyroid hormone |
involved_in |
ISO |
PMID:11604398 |
CAFA |
PMID:11604398 |
RGD:12793028 |
NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
|
|
G |
RFLNA |
refilin A |
acts_upstream_of_or_within involved_in |
ISO IEA |
(PMID:24436304) |
MGI TreeGrafter |
PMID:24436304 |
GO_REF:0000118 |
NCBI chr12:121,737,946...121,903,635
Ensembl chr12:126,164,592...126,191,071
|
|
G |
RFLNB |
refilin B |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:24436304) |
Ensembl TreeGrafter MGI |
PMID:24436304 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr17:359,016...367,464
Ensembl chr17:375,885...381,580
|
|
|
G |
ACVR1 |
activin A receptor type 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
|
|
G |
ACVR2A |
activin A receptor type 2A |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr2B:11,933,683...12,020,287
Ensembl chr2B:152,253,826...152,288,385
|
|
G |
ACVR2B |
activin A receptor type 2B |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063
|
|
G |
ADGRV1 |
adhesion G protein-coupled receptor V1 |
involved_in |
ISO |
(MGI:6211994|PMID:22419726) |
UniProt |
PMID:22419726 |
MGI:6211994 |
NCBI chr 5:24,208,844...24,811,284
Ensembl chr 5:24,341,808...24,945,477
|
|
G |
ADRB2 |
adrenoceptor beta 2 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15724149) |
Ensembl MGI |
PMID:15724149 |
GO_REF:0000107 |
NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
|
|
G |
ALOX5 |
arachidonate 5-lipoxygenase |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
|
|
G |
ANO6 |
anoctamin 6 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr12:43,295,928...43,512,073
Ensembl chr12:44,164,375...44,303,259
|
|
G |
ATP2B1 |
ATPase plasma membrane Ca2+ transporting 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr12:87,107,900...87,229,514
Ensembl chr12:90,427,560...90,495,320
|
|
G |
ATRAID |
all-trans retinoic acid induced differentiation factor |
involved_in |
ISO |
(PMID:21723284) |
UniProt |
PMID:21723284 |
|
NCBI chr2A:27,213,556...27,218,552
Ensembl chr2A:27,301,175...27,306,294
|
|
G |
BMP2 |
bone morphogenetic protein 2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
|
|
G |
BMP4 |
bone morphogenetic protein 4 |
involved_in acts_upstream_of_or_within |
ISO IEA |
(PMID:14749725) |
RGD Ensembl MGI |
PMID:14749725 PMID:15352071 |
GO_REF:0000107 RGD:9068399 |
NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
|
|
G |
BMP6 |
bone morphogenetic protein 6 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
|
|
G |
BMP7 |
bone morphogenetic protein 7 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
|
|
G |
BMPR1A |
bone morphogenetic protein receptor type 1A |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
|
|
G |
BMPR1B |
bone morphogenetic protein receptor type 1B |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 4:87,125,911...87,523,084
Ensembl chr 4:98,088,072...98,195,848
|
|
G |
BMPR2 |
bone morphogenetic protein receptor type 2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
|
|
G |
CCN1 |
cellular communication network factor 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147
|
|
G |
CD276 |
CD276 molecule |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15317945) |
Ensembl MGI |
PMID:15317945 |
GO_REF:0000107 |
NCBI chr15:52,594,719...52,625,047
|
|
G |
CSF1R |
colony stimulating factor 1 receptor |
|
ISO |
|
RGD |
PMID:18434589 |
RGD:151665814 |
NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415
|
|
G |
FAM20C |
FAM20C golgi associated secretory pathway kinase |
acts_upstream_of_or_within |
ISO |
(PMID:17369251), (PMID:22615579) |
MGI |
PMID:17369251 PMID:22615579 |
|
NCBI chr 7:311,468...394,623
|
|
G |
FBN2 |
fibrillin 2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 5:123,673,209...123,953,741
Ensembl chr 5:129,435,248...129,715,711
|
|
G |
FGFR3 |
fibroblast growth factor receptor 3 |
acts_upstream_of_or_within |
ISO |
(PMID:20053668) |
MGI |
PMID:20053668 |
|
NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692
|
|
G |
FZD9 |
frizzled class receptor 9 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
Ensembl chr 7:80,588,167...80,590,337
|
|
G |
GPM6B |
glycoprotein M6B |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr X:6,377,913...6,544,826
Ensembl chr X:13,666,192...13,711,964
|
|
G |
ISG15 |
ISG15 ubiquitin like modifier |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
Ensembl chr 1:927,418...928,491
|
|
G |
KL |
klotho |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr13:14,272,463...14,321,122
Ensembl chr13:32,702,336...32,751,458
|
|
G |
MEF2C |
myocyte enhancer factor 2C |
involved_in |
ISO |
(MGI:5285459|PMID:21652706) |
UniProt |
PMID:21652706 |
MGI:5285459 |
NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426
|
|
G |
MIA3 |
MIA SH3 domain ER export factor 3 |
acts_upstream_of_or_within |
ISO |
(PMID:21606205) |
MGI |
PMID:21606205 |
|
NCBI chr 1:198,291,200...198,339,502
Ensembl chr 1:203,304,237...203,354,919
|
|
G |
NELL1 |
neural EGFL like 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr11:20,697,153...21,600,601
Ensembl chr11:20,607,526...21,508,486
|
|
G |
OSR1 |
odd-skipped related transcription factor 1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr2A:19,333,101...19,340,267
Ensembl chr2A:19,451,067...19,458,229
|
|
G |
OSR2 |
odd-skipped related transciption factor 2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 8:95,590,753...95,598,491
Ensembl chr 8:97,768,980...97,776,669
|
|
G |
P2RX7 |
purinergic receptor P2X 7 |
acts_upstream_of_or_within |
ISO |
(PMID:12677010), (PMID:18519738) |
MGI |
PMID:12677010 PMID:18519738 |
|
NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
|
|
G |
PKDCC |
protein kinase domain containing, cytoplasmic |
involved_in |
ISO |
(MGI:3813934|PMID:19097194) |
UniProt |
PMID:19097194 |
MGI:3813934 |
NCBI chr2A:42,146,153...42,156,652
|
|
G |
PLA2G4A |
phospholipase A2 group IVA |
|
ISO |
|
RGD |
PMID:10807497 |
RGD:1642474 |
NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101
|
|
G |
PTH |
parathyroid hormone |
involved_in |
ISO IEA |
|
RGD Ensembl |
PMID:15758479 PMID:22445539 |
GO_REF:0000107 RGD:7207452 RGD:7242906 |
NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
|
|
G |
PTN |
pleiotrophin |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
|
|
G |
SLC20A2 |
solute carrier family 20 member 2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 8:41,663,200...41,786,314
Ensembl chr 8:39,109,265...39,162,456
|
|
G |
SLC8A1 |
solute carrier family 8 member A1 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038
|
|
G |
SMAD3 |
SMAD family member 3 |
|
ISO |
rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity |
RGD |
PMID:12096832 |
RGD:727387 |
NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
|
|
G |
TENT5A |
terminal nucleotidyltransferase 5A |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 6:79,636,412...79,643,444
Ensembl chr 6:82,901,079...82,908,072
|
|
G |
TFAP2A |
transcription factor AP-2 alpha |
involved_in |
ISO |
(PMID:19578371) |
UniProt |
PMID:19578371 |
|
NCBI chr 6:10,237,834...10,260,843
|
|
G |
TMEM119 |
transmembrane protein 119 |
involved_in |
IEA |
|
Ensembl TreeGrafter |
|
GO_REF:0000107 GO_REF:0000118 |
NCBI chr12:106,166,737...106,173,965
Ensembl chr12:109,563,684...109,564,535
|
|
G |
WNT10B |
Wnt family member 10B |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15728361) |
Ensembl MGI |
PMID:15728361 |
GO_REF:0000107 |
NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734
|
|
G |
WNT4 |
Wnt family member 4 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
|
|
|
G |
ACTN3 |
actinin alpha 3 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429
|
|
G |
ASXL2 |
ASXL transcriptional regulator 2 |
acts_upstream_of_or_within |
ISO |
(PMID:21490954) |
MGI |
PMID:21490954 |
|
NCBI chr2A:25,730,155...25,880,089
Ensembl chr2A:25,832,527...25,973,659
|
|
G |
BMP2 |
bone morphogenetic protein 2 |
involved_in |
IEA |
|
Ensembl |
|
GO_REF:0000107 |
NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
|
|
|
G |
ANKH |
ANKH inorganic pyrophosphate transport regulator |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:10894769), (PMID:7276519) |
Ensembl MGI |
PMID:7276519 PMID:10894769 |
GO_REF:0000107 |
NCBI chr 5:15,014,019...15,175,467
Ensembl chr 5:14,855,914...14,917,729
|
|
G |
BGLAP |
bone gamma-carboxyglutamate protein |
involved_in |
IEA |
|
InterPro |
|
GO_REF:0000002 |
NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
|
|
G |
BMP2K |
BMP2 inducible kinase |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:11500515) |
Ensembl MGI |
PMID:11500515 |
GO_REF:0000107 |
NCBI chr 4:45,278,419...45,420,212
Ensembl chr 4:51,125,098...51,215,526
|
|
G |
COMP |
cartilage oligomeric matrix protein |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:21350216) |
Ensembl MGI |
PMID:21350216 |
GO_REF:0000107 |
NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008
|
|
G |
CYP27B1 |
cytochrome P450 family 27 subfamily B member 1 |
involved_in |
IEA |
|
Ensembl |
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GO_REF:0000107 |
NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
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G |
DDR2 |
discoidin domain receptor tyrosine kinase 2 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:138,048,730...138,200,426
Ensembl chr 1:141,932,158...141,990,766
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G |
ECM1 |
extracellular matrix protein 1 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:20138147) |
Ensembl TreeGrafter MGI |
PMID:20138147 |
GO_REF:0000107 GO_REF:0000118 |
NCBI chr 1:125,853,337...125,858,904
Ensembl chr 1:129,502,041...129,507,819
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G |
ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
involved_in |
IEA |
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TreeGrafter |
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GO_REF:0000118 |
NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
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G |
FGF23 |
fibroblast growth factor 23 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:15579309) |
Ensembl MGI |
PMID:15579309 |
GO_REF:0000107 |
NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000
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G |
GJA1 |
gap junction protein alpha 1 |
acts_upstream_of_or_within |
ISO |
(PMID:21346198) |
MGI |
PMID:21346198 |
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NCBI chr 6:119,213,513...119,227,617
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G |
MATN1 |
matrilin 1 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:16877353) |
Ensembl MGI |
PMID:16877353 |
GO_REF:0000107 |
NCBI chr 1:29,984,376...29,996,430
Ensembl chr 1:31,011,638...31,021,695
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G |
MGP |
matrix Gla protein |
involved_in |
IEA |
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InterPro |
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GO_REF:0000002 |
NCBI chr12:14,887,806...14,891,796
Ensembl chr12:15,284,883...15,288,523
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G |
NBR1 |
NBR1 autophagy cargo receptor |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr17:14,119,638...14,197,827
Ensembl chr17:14,351,229...14,390,597
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G |
NOTUM |
notum, palmitoleoyl-protein carboxylesterase |
acts_upstream_of_or_within |
ISO |
(PMID:30622831) |
MGI |
PMID:30622831 |
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NCBI chr17:76,353,528...76,364,634
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G |
S1PR1 |
sphingosine-1-phosphate receptor 1 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987
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G |
SGMS2 |
sphingomyelin synthase 2 |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr 4:100,329,642...100,420,398
Ensembl chr 4:110,936,358...110,992,887
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G |
STATH |
statherin |
involved_in |
IEA |
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InterPro UniProt |
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GO_REF:0000002 GO_REF:0000104 |
NCBI chr 4:54,234,876...54,241,349
Ensembl chr 4:60,571,712...60,578,215
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G |
SUV39H1 |
SUV39H1 histone lysine methyltransferase |
acts_upstream_of_or_within |
ISO |
(PMID:23695662) |
MGI |
PMID:23695662 |
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NCBI chr X:40,993,911...41,007,362
Ensembl chr X:48,855,494...48,868,131
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G |
TWIST1 |
twist family bHLH transcription factor 1 |
involved_in |
ISO |
(PMID:19597909) |
BHF-UCL |
PMID:19597909 |
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NCBI chr 7:19,761,041...19,765,665
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G |
TXLNG |
taxilin gamma |
involved_in |
IEA |
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Ensembl |
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GO_REF:0000107 |
NCBI chr X:9,407,049...9,465,452
Ensembl chr X:16,776,076...16,831,926
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G |
ZMPSTE24 |
zinc metallopeptidase STE24 |
involved_in acts_upstream_of_or_within |
IEA ISO |
(PMID:23695662) |
Ensembl MGI |
PMID:23695662 |
GO_REF:0000107 |
NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
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Term paths to the root
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