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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ossification
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Accession:GO:0030278 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
Synonyms:exact_synonym: regulation of bone biosynthesis;   regulation of bone formation



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regulation of ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G CCDC134 coiled-coil domain containing 134 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:22,692,503...22,724,871
Ensembl chr22:40,778,254...40,804,191
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 acts_upstream_of_or_within ISO (PMID:19767743) MGI PMID:19767743 NCBI chr11:46,236,384...46,280,145
Ensembl chr11:46,788,561...46,830,246
JBrowse link
G CSF1 colony stimulating factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12865350) Ensembl
MGI
PMID:12865350 GO_REF:0000107 NCBI chr 1:112,555,755...112,575,894
Ensembl chr 1:127,764,916...127,781,943
JBrowse link
G DHRS3 dehydrogenase/reductase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24005908) Ensembl
MGI
PMID:24005908 GO_REF:0000107 NCBI chr 1:11,319,109...11,370,463
Ensembl chr 1:12,533,696...12,584,381
JBrowse link
G EGR2 early growth response 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:8565822) Ensembl
MGI
PMID:8565822 GO_REF:0000107 NCBI chr10:59,320,073...59,326,869
Ensembl chr10:61,648,364...61,652,846
JBrowse link
G ESRRA estrogen related receptor alpha ISO RGD PMID:12193582 RGD:625668 NCBI chr11:59,662,565...59,673,789
Ensembl chr11:63,009,295...63,018,744
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692
JBrowse link
G GDF10 growth differentiation factor 10 ISO RGD PMID:12270110 RGD:632791 NCBI chr10:46,498,600...46,511,933 JBrowse link
G INTU inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25774014) Ensembl
MGI
PMID:25774014 GO_REF:0000107 NCBI chr 4:119,793,245...119,890,949
Ensembl chr 4:131,109,733...131,186,590
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20053668) Ensembl
MGI
PMID:20053668 GO_REF:0000107 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335
JBrowse link
G MAPK14 mitogen-activated protein kinase 14 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20053668) Ensembl
MGI
PMID:20053668 GO_REF:0000107 NCBI chr 6:35,586,847...35,683,041
Ensembl chr 6:36,788,233...36,871,114
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20053668) Ensembl
MGI
PMID:20053668 GO_REF:0000107 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G P3H1 prolyl 3-hydroxylase 1 acts_upstream_of_or_within ISO (PMID:20363744) MGI PMID:20363744 NCBI chr 1:42,046,128...42,065,718
Ensembl chr 1:43,423,900...43,443,336
JBrowse link
G PBX1 PBX homeobox 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11566859) Ensembl
MGI
PMID:11566859 GO_REF:0000107 NCBI chr 1:139,985,392...140,311,845
Ensembl chr 1:143,778,701...144,104,797
JBrowse link
G PRL prolactin ISO RGD PMID:17218965 RGD:1642577 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829
JBrowse link
G PTGER4 prostaglandin E receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10749873) Ensembl
MGI
PMID:10749873 GO_REF:0000107 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148
JBrowse link
G RSAD2 radical S-adenosyl methionine domain containing 2 ISO RGD PMID:10698968 RGD:631877 NCBI chr2A:6,873,821...6,906,087
Ensembl chr2A:7,021,937...7,042,961
JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10213384) Ensembl
MGI
PMID:10213384 GO_REF:0000107 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO RGD PMID:15677765 RGD:1580305 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:45,109,414...45,113,887
Ensembl chr2A:46,039,582...46,044,035
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:79,636,412...79,643,444
Ensembl chr 6:82,901,079...82,908,072
JBrowse link
negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein involved_in ISO
IEA
RGD
Ensembl
PMID:8702833 GO_REF:0000107 RGD:1626074 NCBI chr 3:183,644,223...183,652,620
Ensembl chr 3:192,110,770...192,119,915
JBrowse link
G BCOR BCL6 corepressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:32,497,931...32,624,307
Ensembl chr  X:40,202,235...40,249,986
JBrowse link
G CCR1 C-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:46,107,526...46,114,229
Ensembl chr 3:47,214,688...47,215,755
JBrowse link
G ECM1 extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:125,853,337...125,858,904
Ensembl chr 1:129,502,041...129,507,819
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:22510396), (PMID:25479107), (PMID:30111653) UniProt PMID:22510396 PMID:25479107 PMID:30111653 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G FGF23 fibroblast growth factor 23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000
JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15005853) Ensembl
MGI
PMID:15005853 GO_REF:0000107 NCBI chr  X:41,088,724...41,092,190
Ensembl chr  X:48,945,394...48,953,126
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr15:11,213,870...11,230,619 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17181398) Ensembl
MGI
PMID:17181398 GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G LOC100992309 C-C motif chemokine 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,704,738...20,706,641
Ensembl chr17:21,000,709...21,002,610
JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11790802) Ensembl
MGI
PMID:11790802 GO_REF:0000107 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:12421822), (PMID:15843468)
(PMID:22766095)
MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chr 4:80,125,612...80,139,539
Ensembl chr 4:90,838,938...90,864,332
JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chr12:34,442,913...34,452,016
Ensembl chr12:35,168,173...35,177,253
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (PMID:11371614) MGI PMID:11371614 NCBI chr17:66,028,737...66,034,122 JBrowse link
G SRGN serglycin involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr10:65,554,873...65,572,108
Ensembl chr10:68,089,392...68,106,250
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464
JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr15:11,213,870...11,230,619 JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
JBrowse link
G RFLNA refilin A acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24436304) MGI
TreeGrafter
PMID:24436304 GO_REF:0000118 NCBI chr12:121,737,946...121,903,635
Ensembl chr12:126,164,592...126,191,071
JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:24436304) Ensembl
TreeGrafter
MGI
PMID:24436304 GO_REF:0000107 GO_REF:0000118 NCBI chr17:359,016...367,464
Ensembl chr17:375,885...381,580
JBrowse link
negative regulation of ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B involved_in ISO (PMID:22155034) UniProt PMID:22155034 NCBI chr12:36,765,655...36,811,355
Ensembl chr12:37,541,867...37,566,660
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:16177600 RGD:1598747 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G BCL2 BCL2 apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:9008714) Ensembl
MGI
PMID:9008714 GO_REF:0000107 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100
JBrowse link
G BMP3 bone morphogenetic protein 3 involved_in ISO (PMID:15269709) UniProt PMID:15269709 NCBI chr 4:43,143,784...43,170,854
Ensembl chr 4:48,992,266...49,019,205
JBrowse link
G CALCA calcitonin related polypeptide alpha involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12488435) Ensembl
MGI
PMID:12488435 GO_REF:0000107 NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267
JBrowse link
G CALCR calcitonin receptor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:14970190) Ensembl
MGI
PMID:14970190 GO_REF:0000107 NCBI chr 7:85,382,167...85,532,562
Ensembl chr 7:98,975,906...99,047,162
JBrowse link
G CHSY1 chondroitin sulfate synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:79,901,340...79,976,067
Ensembl chr15:99,186,705...99,260,591
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 ISO RGD PMID:32231239 RGD:32716373 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:18505822) RGD
UniProt
PMID:18505822 PMID:21773994 RGD:6907379 NCBI chr10:48,950,704...48,953,815
Ensembl chr10:51,084,027...51,089,776
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 acts_upstream_of_or_within ISO (PMID:9662402) MGI PMID:9662402 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G GDF10 growth differentiation factor 10 involved_in ISO (PMID:22155034) UniProt PMID:22155034 NCBI chr10:46,498,600...46,511,933 JBrowse link
G GFRA4 GDNF family receptor alpha 4 acts_upstream_of_or_within ISO (PMID:16497798) MGI PMID:16497798 NCBI chr20:3,740,538...3,745,601 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G KREMEN1 kringle containing transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:10,128,326...10,202,548
Ensembl chr22:27,828,011...28,031,917
JBrowse link
G KREMEN2 kringle containing transmembrane protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,905,397...1,910,249
Ensembl chr16:3,078,086...3,082,325
JBrowse link
G LRP4 LDL receptor related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,808,090...46,868,649
Ensembl chr11:47,366,321...47,411,105
JBrowse link
G MDK midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426
JBrowse link
G MKX mohawk homeobox ISO RGD PMID:27370800 RGD:40924660 NCBI chr10:27,820,454...27,893,373
Ensembl chr10:28,181,483...28,254,311
JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
G P2RY2 purinergic receptor P2Y2 ISO RGD PMID:12210747 RGD:729594 NCBI chr11:68,294,366...68,319,118
Ensembl chr11:71,532,958...71,534,091
JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO RGD PMID:17537919 RGD:1642610 NCBI chr 8:26,580,855...26,729,378
Ensembl chr 8:23,869,825...23,932,474
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:21493891) BHF-UCL PMID:21493891 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683
JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in
acts_upstream_of_or_within
ISO (PMID:19254787)
(PMID:15677765)
UniProt
MGI
PMID:15677765 PMID:19254787 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SMAD2 SMAD family member 2 involved_in ISO (PMID:22155034) UniProt PMID:22155034 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530
JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO (PMID:22155034) UniProt PMID:22155034 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SMAD6 SMAD family member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,648,709...45,728,821
Ensembl chr15:63,923,379...64,001,154
JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:29503843) CACAO PMID:29503843 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:15820682) MGI PMID:15820682 NCBI chr 7:90,995,923...91,112,240
Ensembl chr 7:104,500,965...104,568,046
JBrowse link
G SOST sclerostin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23918385) Ensembl
MGI
PMID:23918385 GO_REF:0000107 NCBI chr17:13,639,088...13,644,152
Ensembl chr17:13,804,374...13,809,432
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (PMID:29503843)
(PMID:20056916)
CACAO
UniProt
PMID:20056916 PMID:29503843 NCBI chr17:66,028,737...66,034,122 JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15820682) Ensembl
MGI
PMID:15820682 GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973
JBrowse link
G TMEM53 transmembrane protein 53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:43,955,734...43,977,107
Ensembl chr 1:45,305,359...45,343,109
JBrowse link
G TPH1 tryptophan hydroxylase 1 ISO RGD PMID:20139991 RGD:5686362 NCBI chr11:18,070,576...18,099,539
Ensembl chr11:17,754,893...17,778,076
JBrowse link
G VDR vitamin D receptor ISO RGD PMID:32231239 RGD:32716373 NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192
JBrowse link
positive regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:44,994,175...45,133,490
Ensembl chr2B:162,234,823...162,297,805
JBrowse link
G ACVR2A activin A receptor type 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:11,933,683...12,020,287
Ensembl chr2B:152,253,826...152,288,385
JBrowse link
G ACVR2B activin A receptor type 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063
JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in ISO (PMID:22419726) UniProt PMID:22419726 NCBI chr 5:24,208,844...24,811,284
Ensembl chr 5:24,341,808...24,945,477
JBrowse link
G ADRB2 adrenoceptor beta 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15724149) Ensembl
MGI
PMID:15724149 GO_REF:0000107 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016
JBrowse link
G ANO6 anoctamin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:43,295,928...43,512,073
Ensembl chr12:44,164,375...44,303,259
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:87,107,900...87,229,514
Ensembl chr12:90,427,560...90,495,320
JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor involved_in ISO (PMID:21723284) UniProt PMID:21723284 NCBI chr2A:27,213,556...27,218,552
Ensembl chr2A:27,301,175...27,306,294
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:14749725) RGD
Ensembl
MGI
PMID:14749725 PMID:15352071 GO_REF:0000107 RGD:9068399 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G BMP7 bone morphogenetic protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:83,185,040...83,353,239
Ensembl chr10:86,837,469...86,912,912
JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:87,125,911...87,523,084
Ensembl chr 4:98,088,072...98,195,848
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G CCN1 cellular communication network factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147
JBrowse link
G CD276 CD276 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15317945) Ensembl
MGI
PMID:15317945 GO_REF:0000107 NCBI chr15:52,594,719...52,625,047 JBrowse link
G CSF1R colony stimulating factor 1 receptor ISO RGD PMID:18434589 RGD:151665814 NCBI chr 5:145,478,725...145,537,858
Ensembl chr 5:151,483,572...151,517,415
JBrowse link
G FAM20C FAM20C golgi associated secretory pathway kinase acts_upstream_of_or_within ISO (PMID:17369251), (PMID:22615579) MGI PMID:17369251 PMID:22615579 NCBI chr 7:311,468...394,623 JBrowse link
G FBN2 fibrillin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:123,673,209...123,953,741
Ensembl chr 5:129,435,248...129,715,711
JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:20053668) MGI PMID:20053668 NCBI chr 4:1,933,172...1,948,742
Ensembl chr 4:1,843,774...1,861,692
JBrowse link
G FZD9 frizzled class receptor 9 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:80,588,167...80,590,337 JBrowse link
G GPM6B glycoprotein M6B involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:6,377,913...6,544,826
Ensembl chr  X:13,666,192...13,711,964
JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 1:927,418...928,491 JBrowse link
G KL klotho involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:14,272,463...14,321,122
Ensembl chr13:32,702,336...32,751,458
JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (PMID:21652706) UniProt PMID:21652706 NCBI chr 5:26,480,489...26,650,813
Ensembl chr 5:26,681,700...26,786,426
JBrowse link
G MIA3 MIA SH3 domain ER export factor 3 acts_upstream_of_or_within ISO (PMID:21606205) MGI PMID:21606205 NCBI chr 1:198,291,200...198,339,502
Ensembl chr 1:203,304,237...203,354,919
JBrowse link
G NELL1 neural EGFL like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,697,153...21,600,601
Ensembl chr11:20,607,526...21,508,486
JBrowse link
G OSR1 odd-skipped related transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:19,333,101...19,340,267
Ensembl chr2A:19,451,067...19,458,229
JBrowse link
G OSR2 odd-skipped related transciption factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:95,590,753...95,598,491
Ensembl chr 8:97,768,980...97,776,669
JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:12677010), (PMID:18519738) MGI PMID:12677010 PMID:18519738 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in ISO (PMID:19097194) UniProt PMID:19097194 NCBI chr2A:42,146,153...42,156,652 JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO RGD PMID:10807497 RGD:1642474 NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101
JBrowse link
G PTH parathyroid hormone involved_in ISO
IEA
RGD
Ensembl
PMID:15758479 PMID:22445539 GO_REF:0000107 RGD:7207452 RGD:7242906 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
JBrowse link
G PTN pleiotrophin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link
G SLC20A2 solute carrier family 20 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:41,663,200...41,786,314
Ensembl chr 8:39,109,265...39,162,456
JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:40,169,339...40,586,546
Ensembl chr2A:40,939,900...41,363,038
JBrowse link
G SMAD3 SMAD family member 3 ISO rat gene expressed in mouse osteoblastic cell line MC3T3-E1; TGF-beta down-regulates this activity RGD PMID:12096832 RGD:727387 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G TENT5A terminal nucleotidyltransferase 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:79,636,412...79,643,444
Ensembl chr 6:82,901,079...82,908,072
JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr 6:10,237,834...10,260,843 JBrowse link
G TMEM119 transmembrane protein 119 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr12:106,166,737...106,173,965
Ensembl chr12:109,563,684...109,564,535
JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15728361) Ensembl
MGI
PMID:15728361 GO_REF:0000107 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734
JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801
JBrowse link
positive regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429
JBrowse link
G ASXL2 ASXL transcriptional regulator 2 acts_upstream_of_or_within ISO (PMID:21490954) MGI PMID:21490954 NCBI chr2A:25,730,155...25,880,089
Ensembl chr2A:25,832,527...25,973,659
JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
positive regulation of ossification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:30067871 RGD:329412472 NCBI chr 1:143,239,576...143,404,038
Ensembl chr 1:147,023,671...147,129,705
JBrowse link
G BMP2 bone morphogenetic protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:9213002)
(PMID:15820682), (PMID:21324897)
MGI
Ensembl
PMID:9213002 PMID:15820682 PMID:21324897 GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610
JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:8358941)
PMID:7911662
(PMID:14749725)
RGD
MGI
Ensembl
PMID:7911662 PMID:8358941 PMID:14749725 PMID:17112416 GO_REF:0000107 RGD:1643600 RGD:632977 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:89,631,622...89,823,438
Ensembl chr2B:207,780,741...207,961,072
JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:116,105,935...116,114,241
Ensembl chr 8:118,855,445...118,865,039
JBrowse link
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (PMID:15469977) MGI PMID:15469977 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973
JBrowse link
G NELL1 neural EGFL like 1 involved_in ISO
IEA
RGD
TreeGrafter
PMID:19493425 GO_REF:0000118 RGD:2314454 NCBI chr11:20,697,153...21,600,601
Ensembl chr11:20,607,526...21,508,486
JBrowse link
G NIPBL NIPBL cohesin loading factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19763162) Ensembl
MGI
PMID:19763162 GO_REF:0000107 NCBI chr 5:73,306,527...73,491,367
Ensembl chr 5:78,585,649...78,698,184
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:18257653 RGD:2304114 NCBI chr20:3,157,246...3,159,013 JBrowse link
G P2RX7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:16269410), (PMID:18519738) MGI PMID:16269410 PMID:18519738 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:14751573 PMID:17106877 RGD:10043372 RGD:10045950 NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148
JBrowse link
G PTH parathyroid hormone ISO RGD PMID:15758479 RGD:7207452 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
JBrowse link
G PTN pleiotrophin involved_in ISO PMID:9817766 UniProt PMID:9817766 RGD:14397563 NCBI chr 7:129,184,786...129,300,815
Ensembl chr 7:141,701,430...141,705,623
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in ISO (PMID:29644115) UniProt PMID:29644115 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762
JBrowse link
G RUNX2 RUNX family transcription factor 2 ISO RGD PMID:11784711 RGD:1601657 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
JBrowse link
G SCUBE2 signal peptide, CUB domain and EGF like domain containing 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:25639508) Ensembl
MGI
PMID:25639508 GO_REF:0000107 NCBI chr11:9,146,533...9,219,816
Ensembl chr11:8,888,668...8,959,677
JBrowse link
G SETD2 SET domain containing 2, histone lysine methyltransferase ISO RGD PMID:30746871 RGD:151665130 NCBI chr 3:46,916,615...47,064,046
Ensembl chr 3:48,018,517...48,163,999
JBrowse link
G SOX11 SRY-box transcription factor 11 involved_in ISO (PMID:20626275)
(PMID:15254231)
UniProt PMID:15254231 PMID:20626275 NCBI chr2A:5,699,738...5,711,210 JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:17204323 RGD:2304342 NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:17204323 RGD:2304342 NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018
JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:15647824 RGD:1601663 NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960
JBrowse link
G TOB2 transducer of ERBB2, 2 acts_upstream_of_or_within ISO (PMID:18358842) MGI PMID:18358842 NCBI chr22:22,329,783...22,344,795 JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19723499)
(PMID:15728361)
(PMID:17708715)
Ensembl
MGI
PMID:15728361 PMID:17708715 PMID:19723499 GO_REF:0000107 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734
JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:55,396,279...55,418,579
Ensembl chr 3:56,621,380...56,638,051
JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,938,414...109,133,819
Ensembl chr11:112,780,380...112,977,164
JBrowse link
regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKH ANKH inorganic pyrophosphate transport regulator involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:10894769), (PMID:7276519) Ensembl
MGI
PMID:7276519 PMID:10894769 GO_REF:0000107 NCBI chr 5:15,014,019...15,175,467
Ensembl chr 5:14,855,914...14,917,729
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:131,583,789...131,586,459
Ensembl chr 1:135,413,871...135,416,432
JBrowse link
G BMP2K BMP2 inducible kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:11500515) Ensembl
MGI
PMID:11500515 GO_REF:0000107 NCBI chr 4:45,278,419...45,420,212
Ensembl chr 4:51,125,098...51,215,526
JBrowse link
G COMP cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21350216) Ensembl
MGI
PMID:21350216 GO_REF:0000107 NCBI chr19:18,222,270...18,230,936
Ensembl chr19:19,229,562...19,238,008
JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822
JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:138,048,730...138,200,426
Ensembl chr 1:141,932,158...141,990,766
JBrowse link
G ECM1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20138147) Ensembl
TreeGrafter
MGI
PMID:20138147 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:125,853,337...125,858,904
Ensembl chr 1:129,502,041...129,507,819
JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:129,591,858...129,673,000
Ensembl chr 6:133,698,640...133,783,644
JBrowse link
G FGF23 fibroblast growth factor 23 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15579309) Ensembl
MGI
PMID:15579309 GO_REF:0000107 NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000
JBrowse link
G GJA1 gap junction protein alpha 1 acts_upstream_of_or_within ISO (PMID:21346198) MGI PMID:21346198 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G MATN1 matrilin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16877353) Ensembl
MGI
PMID:16877353 GO_REF:0000107 NCBI chr 1:29,984,376...29,996,430
Ensembl chr 1:31,011,638...31,021,695
JBrowse link
G MGP matrix Gla protein involved_in IEA InterPro GO_REF:0000002 NCBI chr12:14,887,806...14,891,796
Ensembl chr12:15,284,883...15,288,523
JBrowse link
G NBR1 NBR1 autophagy cargo receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,119,638...14,197,827
Ensembl chr17:14,351,229...14,390,597
JBrowse link
G NOTUM notum, palmitoleoyl-protein carboxylesterase acts_upstream_of_or_within ISO (PMID:30622831) MGI PMID:30622831 NCBI chr17:76,353,528...76,364,634 JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:103,893,199...103,898,381
Ensembl chr 1:102,608,839...102,609,987
JBrowse link
G SGMS2 sphingomyelin synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,329,642...100,420,398
Ensembl chr 4:110,936,358...110,992,887
JBrowse link
G STATH statherin involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr 4:54,234,876...54,241,349
Ensembl chr 4:60,571,712...60,578,215
JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:23695662) MGI PMID:23695662 NCBI chr  X:40,993,911...41,007,362
Ensembl chr  X:48,855,494...48,868,131
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 involved_in ISO (PMID:19597909) BHF-UCL PMID:19597909 NCBI chr 7:19,761,041...19,765,665 JBrowse link
G TXLNG taxilin gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:9,407,049...9,465,452
Ensembl chr  X:16,776,076...16,831,926
JBrowse link
G ZMPSTE24 zinc metallopeptidase STE24 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23695662) Ensembl
MGI
PMID:23695662 GO_REF:0000107 NCBI chr 1:39,545,264...39,589,721
Ensembl chr 1:40,869,076...40,912,747
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16624
    multicellular organismal process 7284
      ossification 448
        regulation of ossification 142
          negative regulation of ossification + 51
          positive regulation of ossification + 63
          regulation of bone mineralization + 83
Path 2
Term Annotations click to browse term
  biological_process 16624
    biological regulation 11618
      regulation of biological process 11245
        regulation of multicellular organismal process 3149
          regulation of ossification 142
            negative regulation of ossification + 51
            positive regulation of ossification + 63
            regulation of bone mineralization + 83
paths to the root