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ONTOLOGY REPORT - ANNOTATIONS

Term:apoptotic nuclear changes
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Accession:GO:0030262 term browser browse the term
Definition:Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
Synonyms:narrow_synonym: apoptotic nuclear change


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apoptotic nuclear changes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor, type IC involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:58,157,465...58,247,909
Ensembl chr 2:58,157,465...58,247,907 		JBrowse link
G Blcap bladder cancer associated protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:157,398,282...157,408,281
Ensembl chr 2:157,398,282...157,413,194 		JBrowse link
G Cd24a CD24a antigen acts_upstream_of_or_within IDA (PMID:14707049) MGI PMID:14707049 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:96,798,251...96,807,359
Ensembl chr11:96,798,252...96,807,322 		JBrowse link
G Col6a1 collagen, type VI, alpha 1 acts_upstream_of_or_within IMP (PMID:14625552) MGI PMID:14625552 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002 		JBrowse link
G Dedd2 death effector domain-containing DNA binding protein 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:24,899,337...24,920,035
Ensembl chr 7:24,899,340...24,920,040 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in ISO RGD
MGI		 PMID:20841353 PMID:21874357 GO_REF:0000096 MGI:4417868 RGD:150540304 RGD:150540305 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Sharpin SHANK-associated RH domain interacting protein acts_upstream_of_or_within IMP (PMID:7792947) MGI PMID:7792947 NCBI chr15:76,231,240...76,235,310
Ensembl chr15:76,231,240...76,235,311 		JBrowse link
apoptotic chromosome condensation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:54,879,618...54,924,422
Ensembl chr14:54,879,618...54,924,388 		JBrowse link
G Dffb DNA fragmentation factor, beta subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:154,048,904...154,059,578
Ensembl chr 4:154,048,906...154,059,583 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signalling 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:121,769,116...121,785,454
Ensembl chr 7:121,769,116...121,785,430 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555 		JBrowse link
G Kdm4a lysine (K)-specific demethylase 4A involved_in ISO RGD
MGI		 PMID:24747049 GO_REF:0000096 MGI:4417868 RGD:9587433 NCBI chr 4:117,994,154...118,037,216
Ensembl chr 4:117,994,154...118,037,240 		JBrowse link
G Top2a topoisomerase (DNA) II alpha involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor, alpha subunit involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104 		JBrowse link
G Dffb DNA fragmentation factor, beta subunit involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:15572351) RGD
GO_Central
MGI		 PMID:11425895 PMID:15572351 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:628524 NCBI chr 4:154,048,904...154,059,578
Ensembl chr 4:154,048,906...154,059,583 		JBrowse link
G Dicer1 dicer 1, ribonuclease type III involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211 		JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 involved_in
acts_upstream_of_or_within		 ISO
IBA
IDA		 (PMID:12050166) MGI
GO_Central		 PMID:12050166 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr14:14,475,014...14,504,586
Ensembl chr14:14,475,200...14,505,240 		JBrowse link
G Dnase2a deoxyribonuclease II alpha involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:85,635,384...85,638,332
Ensembl chr 8:85,635,189...85,649,544 		JBrowse link
G Dnase2b deoxyribonuclease II beta involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:146,275,488...146,322,815
Ensembl chr 3:146,286,740...146,321,351 		JBrowse link
G Endog endonuclease G acts_upstream_of_or_within
involved_in		 IMP
IBA		 (PMID:14663139) MGI
GO_Central		 PMID:14663139 GO_REF:0000033 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081 		JBrowse link
G Exog exo/endonuclease G involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:119,274,026...119,294,584
Ensembl chr 9:119,274,009...119,294,583 		JBrowse link
G Foxl2 forkhead box L2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:98,837,495...98,840,601
Ensembl chr 9:98,837,341...98,840,596 		JBrowse link
G Vps54 VPS54 GARP complex subunit involved_in IMP (PMID:11403940) MGI PMID:11403940 NCBI chr11:21,189,032...21,271,133
Ensembl chr11:21,189,281...21,271,136 		JBrowse link
negative regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dffa DNA fragmentation factor, alpha subunit involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:15572351)
(PMID:10601318), (PMID:14663139)		 MGI PMID:10601318 PMID:14663139 PMID:15572351 GO_REF:0000119 MGI:4834177 NCBI chr 4:149,188,599...149,205,110
Ensembl chr 4:149,188,603...149,205,104 		JBrowse link
G Dffb DNA fragmentation factor, beta subunit involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:154,048,904...154,059,578
Ensembl chr 4:154,048,906...154,059,583 		JBrowse link
G Mir146 microRNA 146 involved_in ISO (PMID:28433754) ARUK-UCL PMID:28433754 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Nmnat1 nicotinamide nucleotide adenylyltransferase 1 involved_in ISO RGD
MGI		 PMID:27184051 GO_REF:0000096 MGI:4417868 RGD:13781945 NCBI chr 4:149,552,026...149,569,667
Ensembl chr 4:149,552,029...149,569,659 		JBrowse link
G Pam16 presequence translocase-asssociated motor 16 ISO RGD PMID:24069394 RGD:13462066 NCBI chr16:4,434,330...4,442,810
Ensembl chr16:4,434,328...4,442,852 		JBrowse link
nuclear fragmentation involved in apoptotic nuclear change term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555 		JBrowse link
positive regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Endog endonuclease G involved_in ISO RGD
MGI		 PMID:16407272 GO_REF:0000096 MGI:4417868 RGD:9685355 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO RGD
MGI		 PMID:25726415 GO_REF:0000096 MGI:4417868 RGD:155260369 NCBI chr 2:179,966,881...179,977,296
Ensembl chr 2:179,966,926...179,976,492 		JBrowse link
G Hsf1 heat shock factor 1 involved_in ISO RGD
MGI		 PMID:21192280 GO_REF:0000096 MGI:4417868 RGD:10403035 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 involved_in ISO RGD
MGI		 PMID:15125883 GO_REF:0000096 MGI:4417868 RGD:10402776 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923 		JBrowse link
G Il6 interleukin 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
regulation of apoptotic DNA fragmentation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 acts_upstream_of_or_within IGI (PMID:15703386) MGI PMID:15703386 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within IGI (PMID:15703386) MGI PMID:15703386 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890 		JBrowse link
G Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A involved_in IDA (MGI:1203887|PMID:9564035) BHF-UCL PMID:9564035 MGI:1203887 NCBI chr18:67,476,634...67,500,864
Ensembl chr18:67,476,674...67,500,855 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17545
      execution phase of apoptosis 85
        cellular component disassembly involved in execution phase of apoptosis 36
          apoptotic nuclear changes 35
            apoptotic DNA fragmentation + 22
            apoptotic chromosome condensation 6
            nuclear fragmentation involved in apoptotic nuclear change 1
Path 2
Term Annotations click to browse term
  biological_process 28573
    cellular process 17545
      cell death 2253
        programmed cell death 2253
          apoptotic process 2166
            execution phase of apoptosis 85
              cellular component disassembly involved in execution phase of apoptosis 36
                apoptotic nuclear changes 35
                  apoptotic DNA fragmentation + 22
                  apoptotic chromosome condensation 6
                  nuclear fragmentation involved in apoptotic nuclear change 1
paths to the root