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ONTOLOGY REPORT - ANNOTATIONS

Term:myofibril assembly
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Accession:GO:0030239 term browser browse the term
Definition:Formation of myofibrils, the repeating units of striated muscle.

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show annotations for term's descendants           Sort by:
myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capn3 calpain 3 acts_upstream_of_or_within ISO (PMID:15138196) MGI PMID:15138196 NCBI chrNW_004955416:9,070,479...9,121,099
Ensembl chrNW_004955416:9,070,399...9,117,794 		JBrowse link
G Klhl41 kelch like family member 41 involved_in ISO (MGI:5486546|PMID:18178185) UniProt PMID:18178185 MGI:5486546 NCBI chrNW_004955449:5,023,362...5,041,006
Ensembl chrNW_004955449:5,023,362...5,061,705 		JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO (PMID:10712438) MGI PMID:10712438 NCBI chrNW_004955467:8,298,514...8,427,459
Ensembl chrNW_004955467:8,298,527...8,427,459 		JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 acts_upstream_of_or_within ISO (PMID:14960280) MGI PMID:14960280 NCBI chrNW_004955445:11,405,195...11,407,819
Ensembl chrNW_004955445:11,405,195...11,407,819 		JBrowse link
G Tmod1 tropomodulin 1 acts_upstream_of_or_within ISO (PMID:14657235) MGI PMID:14657235 NCBI chrNW_004955419:27,841,424...27,915,540
Ensembl chrNW_004955419:27,841,424...27,915,540 		JBrowse link
cardiac muscle thin filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nebl nebulette involved_in ISO (PMID:11822876), (PMID:18823973) UniProt PMID:11822876 PMID:18823973 NCBI chrNW_004955429:7,559,994...7,730,683
Ensembl chrNW_004955429:7,358,758...7,725,648 		JBrowse link
cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actc1 actin alpha cardiac muscle 1 acts_upstream_of_or_within ISO (PMID:9114002) MGI PMID:9114002 NCBI chrNW_004955416:2,139,541...2,144,678
Ensembl chrNW_004955416:2,137,101...2,145,416 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 involved_in ISO (MGI:2447926|PMID:12507422) BHF-UCL PMID:12507422 MGI:2447926 NCBI chrNW_004955476:155,913...176,122
Ensembl chrNW_004955476:154,917...176,616 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 acts_upstream_of_or_within ISO (PMID:23213483) MGI PMID:23213483 NCBI chrNW_004955402:22,822,060...23,277,993
Ensembl chrNW_004955402:22,821,710...23,279,222 		JBrowse link
G Myh10 myosin heavy chain 10 acts_upstream_of_or_within ISO (PMID:9356462) MGI PMID:9356462 NCBI chrNW_004955467:8,298,514...8,427,459
Ensembl chrNW_004955467:8,298,527...8,427,459 		JBrowse link
G Myl2 myosin light chain 2 acts_upstream_of_or_within ISO (PMID:9422794) MGI PMID:9422794 NCBI chrNW_004955482:7,708,436...7,713,877
Ensembl chrNW_004955482:7,705,912...7,713,870 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in ISO PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chrNW_004955448:254,280...287,451
Ensembl chrNW_004955448:255,119...287,712 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO (MGI:1931346|PMID:11239463) UniProt PMID:11239463 MGI:1931346 NCBI chrNW_004955447:16,570,652...16,613,410
Ensembl chrNW_004955447:16,569,909...16,612,373 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO (MGI:1931346|PMID:11239463) UniProt PMID:11239463 MGI:1931346 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO (PMID:15569937) MGI PMID:15569937 NCBI chrNW_004955437:9,100,546...9,109,305
Ensembl chrNW_004955437:9,098,968...9,107,057 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955451:14,413,657...14,414,735
Ensembl chrNW_004955451:14,413,657...14,414,735 		JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within		 ISO (PMID:11846417), (PMID:9817758)
(PMID:16702235)		 BHF-UCL
MGI		 PMID:9817758 PMID:11846417 PMID:16702235 NCBI chrNW_004955403:18,057,344...18,328,389 JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in ISO (MGI:3689643|PMID:16151019) BHF-UCL PMID:16151019 MGI:3689643 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538 		JBrowse link
negative regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO (PMID:12847114) BHF-UCL PMID:12847114 NCBI chrNW_004955561:326,008...335,911
Ensembl chrNW_004955561:325,944...335,914 		JBrowse link
G Mfn2 mitofusin 2 ISO RGD PMID:24777478 RGD:13204833 NCBI chrNW_004955486:1,937,873...1,962,577
Ensembl chrNW_004955486:1,937,802...1,962,772 		JBrowse link
positive regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp10 bone morphogenetic protein 10 involved_in ISO (PMID:17921333) BHF-UCL PMID:17921333 NCBI chrNW_004955424:16,124,526...16,130,723
Ensembl chrNW_004955424:16,124,464...16,134,012 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) BHF-UCL PMID:12847114 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:12724418 RGD:2312280 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in ISO PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chrNW_004955448:254,280...287,451
Ensembl chrNW_004955448:255,119...287,712 		JBrowse link
G Prkd1 protein kinase D1 ISO RGD PMID:16648482 RGD:243065275 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) BHF-UCL PMID:19091769 MGI:3830437 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555 		JBrowse link
regulation of sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap13 A-kinase anchoring protein 13 involved_in ISO (MGI:5308772|PMID:20139090) UniProt PMID:20139090 MGI:5308772 NCBI chrNW_004955416:19,006,206...19,327,523
Ensembl chrNW_004955416:19,009,485...19,247,626 		JBrowse link
G Ankrd23 ankyrin repeat domain 23 acts_upstream_of_or_within ISO (PMID:17392382) MGI PMID:17392382 NCBI chrNW_004955470:4,195,872...4,200,979
Ensembl chrNW_004955470:4,195,754...4,200,979 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO (PMID:17322895) MGI PMID:17322895 NCBI chrNW_004955526:2,739,099...2,759,640
Ensembl chrNW_004955526:2,728,377...2,759,707 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO (PMID:17875930) MGI PMID:17875930 NCBI chrNW_004955418:22,537,388...22,701,434
Ensembl chrNW_004955418:22,537,285...22,701,434 		JBrowse link
sarcomere organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actg1 actin gamma 1 acts_upstream_of_or_within ISO (PMID:15194427) MGI PMID:15194427 NCBI chrNW_004955506:1,546,678...1,549,611
Ensembl chrNW_004955506:1,546,678...1,552,105 		JBrowse link
G Actn2 actinin alpha 2 involved_in ISO (PMID:25433700) UniProt PMID:25433700 NCBI chrNW_004955492:3,483,704...3,554,831
Ensembl chrNW_004955492:3,483,511...3,555,190 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO PMID:17921333 BHF-UCL PMID:17921333 RGD:2302083 NCBI chrNW_004955424:16,124,526...16,130,723
Ensembl chrNW_004955424:16,124,464...16,134,012 		JBrowse link
G Capn3 calpain 3 acts_upstream_of_or_within ISO (PMID:15138196) MGI PMID:15138196 NCBI chrNW_004955416:9,070,479...9,121,099
Ensembl chrNW_004955416:9,070,399...9,117,794 		JBrowse link
G Casq1 calsequestrin 1 involved_in ISO (MGI:5306707|PMID:22049211) UniProt PMID:22049211 MGI:5306707 NCBI chrNW_004955468:11,967,678...11,978,836
Ensembl chrNW_004955468:11,967,678...11,978,836 		JBrowse link
G Casq2 calsequestrin 2 involved_in ISO (MGI:4453101|PMID:19920148) UniProt PMID:19920148 MGI:4453101 NCBI chrNW_004955435:18,941,975...18,996,027
Ensembl chrNW_004955435:18,941,936...18,996,200 		JBrowse link
G Cfl2 cofilin 2 acts_upstream_of_or_within ISO (PMID:22343409) MGI PMID:22343409 NCBI chrNW_004955409:26,247,050...26,250,082
Ensembl chrNW_004955409:26,246,369...26,250,082 		JBrowse link
G Fhod3 formin homology 2 domain containing 3 acts_upstream_of_or_within ISO PMID:19706596
(PMID:19706596)		 MGI PMID:19706596 RGD:8554207 NCBI chrNW_004955402:22,822,060...23,277,993
Ensembl chrNW_004955402:22,821,710...23,279,222 		JBrowse link
G Flnc filamin C involved_in ISO (PMID:34405687) UniProt PMID:34405687 NCBI chrNW_004955479:9,633,817...9,661,725
Ensembl chrNW_004955479:9,633,598...9,661,777 		JBrowse link
G Itgb1 integrin subunit beta 1 acts_upstream_of_or_within ISO (PMID:9004034) MGI PMID:9004034 NCBI chrNW_004955462:4,454,809...4,483,227
Ensembl chrNW_004955462:4,454,809...4,484,842 		JBrowse link
G Krt8 keratin 8 involved_in ISO PMID:15247274 UniProt PMID:15247274 RGD:1600063 NCBI chrNW_004955458:178,954...190,310 JBrowse link
G Ldb3 LIM domain binding 3 acts_upstream_of_or_within ISO (PMID:11696561) MGI PMID:11696561 NCBI chrNW_004955510:5,738,254...5,793,643
Ensembl chrNW_004955510:5,738,041...5,790,557 		JBrowse link
G Lmod2 leiomodin 2 involved_in ISO (PMID:18403713)
(MGI:5787841|PMID:27274810)		 UniProt PMID:18403713 PMID:27274810 MGI:5787841 RGD:11344939 NCBI chrNW_004955479:5,143,430...5,151,096
Ensembl chrNW_004955479:5,142,609...5,150,656 		JBrowse link
G Mybpc3 myosin binding protein C3 acts_upstream_of_or_within ISO (PMID:16224063), (PMID:17075052)
(PMID:16380103)		 MGI PMID:16224063 PMID:16380103 PMID:17075052 NCBI chrNW_004955422:888,529...902,074
Ensembl chrNW_004955422:888,589...901,725 		JBrowse link
G Mylk3 myosin light chain kinase 3 involved_in ISO PMID:18202317
(MGI:3841874|PMID:18202317)		 BHF-UCL PMID:18202317 MGI:3841874 RGD:8554765 NCBI chrNW_004955448:254,280...287,451
Ensembl chrNW_004955448:255,119...287,712 		JBrowse link
G Myom2 myomesin 2 involved_in ISO (PMID:33033063) FlyBase PMID:33033063 NCBI chrNW_004955403:57,718,120...57,783,338
Ensembl chrNW_004955403:57,717,151...57,772,254 		JBrowse link
G Myoz1 myozenin 1 involved_in ISO (MGI:3831256|PMID:18846255) BHF-UCL PMID:18846255 MGI:3831256 NCBI chrNW_004955437:18,191,514...18,199,122
Ensembl chrNW_004955437:18,191,242...18,199,188 		JBrowse link
G Myoz2 myozenin 2 involved_in ISO (MGI:3513659|PMID:15543153) BHF-UCL PMID:15543153 MGI:3513659 NCBI chrNW_004955428:21,052,352...21,088,468
Ensembl chrNW_004955428:21,052,137...21,101,795 		JBrowse link
G Mypn myopalladin involved_in ISO (PMID:11309420) BHF-UCL PMID:11309420 NCBI chrNW_004955425:20,461,654...20,545,626
Ensembl chrNW_004955425:20,471,047...20,544,105 		JBrowse link
G Neurl2 neuralized E3 ubiquitin protein ligase 2 acts_upstream_of_or_within ISO (PMID:14960280) MGI PMID:14960280 NCBI chrNW_004955445:11,405,195...11,407,819
Ensembl chrNW_004955445:11,405,195...11,407,819 		JBrowse link
G Plec plectin involved_in ISO (PMID:24487589) MGI PMID:24487589 NCBI chrNW_004955454:2,583,138...2,644,308
Ensembl chrNW_004955454:2,583,138...2,643,211 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha acts_upstream_of_or_within ISO (PMID:18316483) MGI PMID:18316483 NCBI chrNW_004955478:4,241,283...4,262,119
Ensembl chrNW_004955478:4,241,283...4,263,087 		JBrowse link
G Six4 SIX homeobox 4 involved_in ISO (MGI:5298278|PMID:21884692) UniProt PMID:21884692 MGI:5298278 NCBI chrNW_004955466:8,902,728...8,915,685
Ensembl chrNW_004955466:8,902,517...8,915,723 		JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO (PMID:15569937) MGI PMID:15569937 NCBI chrNW_004955437:9,100,546...9,109,305
Ensembl chrNW_004955437:9,098,968...9,107,057 		JBrowse link
G Synpo2l synaptopodin 2 like involved_in ISO (MGI:6102963|PMID:29206857) BHF-UCL PMID:29206857 MGI:6102963 NCBI chrNW_004955437:18,177,867...18,186,772
Ensembl chrNW_004955437:18,177,867...18,188,983 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955451:14,413,657...14,414,735
Ensembl chrNW_004955451:14,413,657...14,414,735 		JBrowse link
G Tnnt2 troponin T2, cardiac type acts_upstream_of_or_within ISO (PMID:10449439) MGI PMID:10449439 NCBI chrNW_004955406:37,491,462...37,507,360
Ensembl chrNW_004955406:37,487,154...37,507,639 		JBrowse link
G Tpm1 tropomyosin 1 involved_in ISO (PMID:11273725) BHF-UCL PMID:11273725 NCBI chrNW_004955450:12,197,241...12,223,372
Ensembl chrNW_004955450:12,194,755...12,224,011 		JBrowse link
G Ttn titin involved_in
acts_upstream_of_or_within		 ISO (PMID:11846417), (PMID:9804419), (PMID:9817758)
(PMID:17360664)
(PMID:16702235)		 RGD
BHF-UCL
MGI		 PMID:9804419 PMID:9817758 PMID:11034912 PMID:11846417 PMID:16702235 More... RGD:634444 NCBI chrNW_004955403:18,057,344...18,328,389 JBrowse link
G Wdr1 WD repeat domain 1 acts_upstream_of_or_within ISO (PMID:24840128) MGI PMID:24840128 NCBI chrNW_004955549:2,640,193...2,674,818
Ensembl chrNW_004955549:2,640,195...2,673,969 		JBrowse link
G Xirp1 xin actin binding repeat containing 1 acts_upstream_of_or_within ISO (PMID:17766470) MGI PMID:17766470 NCBI chrNW_004955427:24,778,157...24,787,691
Ensembl chrNW_004955427:24,781,194...24,786,728 		JBrowse link
sarcomerogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk3 myosin light chain kinase 3 involved_in ISO PMID:17885681 BHF-UCL PMID:17885681 RGD:8554371 NCBI chrNW_004955448:254,280...287,451
Ensembl chrNW_004955448:255,119...287,712 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955451:14,413,657...14,414,735
Ensembl chrNW_004955451:14,413,657...14,414,735 		JBrowse link
G Ttn titin involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955403:18,057,344...18,328,389 JBrowse link
skeletal muscle myosin thick filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcap titin-cap involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955451:14,413,657...14,414,735
Ensembl chrNW_004955451:14,413,657...14,414,735 		JBrowse link
G Tmod1 tropomodulin 1 NOT|acts_upstream_of_or_within ISO (PMID:14657235) MGI PMID:14657235 NCBI chrNW_004955419:27,841,424...27,915,540
Ensembl chrNW_004955419:27,841,424...27,915,540 		JBrowse link
G Ttn titin involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955403:18,057,344...18,328,389 JBrowse link
skeletal muscle thin filament assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin alpha 1, skeletal muscle involved_in ISO (PMID:11333380) UniProt PMID:11333380 NCBI chrNW_004955492:8,644,696...8,647,412
Ensembl chrNW_004955492:8,644,146...8,647,523 		JBrowse link
G Actc1 actin alpha cardiac muscle 1 acts_upstream_of_or_within ISO (PMID:9114002) MGI PMID:9114002 NCBI chrNW_004955416:2,139,541...2,144,678
Ensembl chrNW_004955416:2,137,101...2,145,416 		JBrowse link
G Lmod3 leiomodin 3 involved_in ISO (PMID:25250574) UniProt PMID:25250574 NCBI chrNW_004955421:18,728,993...18,744,326
Ensembl chrNW_004955421:18,728,692...18,743,974 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) BHF-UCL PMID:19091769 MGI:3830437 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955451:14,413,657...14,414,735
Ensembl chrNW_004955451:14,413,657...14,414,735 		JBrowse link
G Ttn titin involved_in ISO (PMID:9817758) BHF-UCL PMID:9817758 NCBI chrNW_004955403:18,057,344...18,328,389 JBrowse link
skeletal myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cflar CASP8 and FADD like apoptosis regulator involved_in ISO (MGI:5707584|PMID:21364645) BHF-UCL PMID:21364645 MGI:5707584 NCBI chrNW_004955403:415,092...442,214
Ensembl chrNW_004955403:412,632...434,741 		JBrowse link
G Plec plectin involved_in ISO (PMID:24487589) MGI PMID:24487589 NCBI chrNW_004955454:2,583,138...2,644,308
Ensembl chrNW_004955454:2,583,138...2,643,211 		JBrowse link
ventricular cardiac myofibril assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2a myocyte enhancer factor 2A involved_in ISO (MGI:2429350|PMID:12379849) UniProt PMID:12379849 MGI:2429350 NCBI chrNW_004955416:26,926,753...27,051,171
Ensembl chrNW_004955416:26,953,798...27,051,171 		JBrowse link
G Nkx2-5 NK2 homeobox 5 acts_upstream_of_or_within ISO (PMID:19546853) MGI PMID:19546853 NCBI chrNW_004955408:25,833,649...25,836,673
Ensembl chrNW_004955408:25,832,683...25,836,840 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:3830437|PMID:19091769) BHF-UCL PMID:19091769 MGI:3830437 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12346
    developmental process 5853
      anatomical structure formation involved in morphogenesis 1158
        cellular component assembly involved in morphogenesis 121
          myofibril assembly 56
            cardiac myofibril assembly + 16
            muscle thin filament assembly 0
            sarcomere organization + 41
            sarcomerogenesis 3
            skeletal myofibril assembly + 9
            striated muscle myosin thick filament assembly + 3
            striated muscle paramyosin thick filament assembly 0
Path 2
Term Annotations click to browse term
  biological_process 12346
    cellular process 11480
      cellular component organization or biogenesis 5364
        cellular component organization 5235
          organelle organization 2919
            cytoskeleton organization 1120
              actin cytoskeleton organization 546
                actomyosin structure organization 176
                  myofibril assembly 56
                    cardiac myofibril assembly + 16
                    muscle thin filament assembly 0
                    sarcomere organization + 41
                    sarcomerogenesis 3
                    skeletal myofibril assembly + 9
                    striated muscle myosin thick filament assembly + 3
                    striated muscle paramyosin thick filament assembly 0
paths to the root