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ONTOLOGY REPORT - ANNOTATIONS


Term:monocyte differentiation
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Accession:GO:0030224 term browser browse the term
Definition:The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
Synonyms:exact_synonym: monocyte cell differentiation



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monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA
(PMID:21149635)
GO_REF:0000107
RGD
Ensembl
PMID:21149635 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Csf2 colony stimulating factor 2 acts_upstream_of_or_within ISO (MGI:3842881|PMID:19109256) RGD PMID:19109256 MGI:3842881 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Fasn fatty acid synthase involved_in ISO MGI:3765070 (MGI:5630041|PMID:25565205) RGD PMID:25565205 MGI:5630041 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO MGI:96553 (MGI:3842881|PMID:19109256) RGD PMID:19109256 MGI:3842881 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il31ra interleukin 31 receptor A involved_in ISO (PMID:11877449) RGD PMID:11877449 NCBI chr 2:44,118,748...44,189,943
Ensembl chr 2:44,122,624...44,183,767
JBrowse link
G Il3ra interleukin 3 receptor subunit alpha acts_upstream_of_or_within ISO MGI:96552 (MGI:3842881|PMID:19109256) RGD PMID:19109256 MGI:3842881 NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (MGI:3785353|PMID:18326819) RGD PMID:18326819 MGI:3785353 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:1861125 (MGI:3655015|PMID:16324150) RGD PMID:16324150 MGI:3655015 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299
JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:1857491 (MGI:3785353|PMID:18326819) RGD PMID:18326819 MGI:3785353 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
ISS
(PMID:1912569)
GO_REF:0000024
RGD
UniProt
PMID:1912569 GO_REF:0000024 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Pde1b phosphodiesterase 1B involved_in ISO (PMID:14687666) RGD PMID:14687666 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580
JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO (PMID:14687666) RGD PMID:14687666 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pir pirin involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:20010624)
RGD PMID:20010624 PMID:21873635 RGD:13792537 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:9568716) RGD PMID:9568716 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Sp3 Sp3 transcription factor acts_upstream_of_or_within ISO MGI:2182438 (MGI:2670314|PMID:12676787) RGD PMID:12676787 MGI:2670314 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Thoc5 THO complex 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:19015024)
UniProt
RGD
PMID:19015024 GO_REF:0000024 NCBI chr14:79,758,805...79,792,718
Ensembl chr14:79,758,917...79,792,718
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:21149635) RGD PMID:21149635 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
negative regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA
ISO
GO_REF:0000107
(PMID:14607961)
Ensembl
RGD
PMID:14607961 GO_REF:0000107 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:26542173) RGD PMID:26542173 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (MGI:3848292|PMID:19479052) RGD PMID:19479052 MGI:3848292 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Hoxa7 homeobox A7 involved_in ISO (PMID:14704364) RGD PMID:14704364 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2386884 (MGI:1266928|PMID:9620849)
Ensembl
RGD
PMID:9620849 GO_REF:0000107 MGI:1266928 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS
(PMID:9924025)
GO_REF:0000024
RGD
UniProt
PMID:9924025 GO_REF:0000024 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (MGI:5320487|PMID:22615127) RGD PMID:22615127 MGI:5320487 NCBI chr 3:168,497,294...168,567,799
Ensembl chr 3:168,499,583...168,568,782
JBrowse link
positive regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:12393560) RGD PMID:12393560 NCBI chr15:28,102,112...28,147,001
Ensembl chr15:28,102,112...28,147,001
JBrowse link
G Cd4 Cd4 molecule involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (MGI:893319|PMID:9215625) RGD PMID:9215625 MGI:893319 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 involved_in ISO (PMID:19569129) RGD PMID:19569129 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (MGI:5319610|PMID:17713547) RGD PMID:17713547 MGI:5319610 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:28389358) RGD PMID:28389358 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
JBrowse link
G Il34 interleukin 34 involved_in IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:23409120)
Ensembl
RGD
PMID:23409120 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr19:38,714,990...38,782,749
Ensembl chr19:38,714,991...38,764,000
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA murine WEHI-3B D+ cells with or without retinoic acid RGD PMID:7947389 RGD:2291846 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISO
ISS
(PMID:26542173)
GO_REF:0000024
RGD
UniProt
PMID:26542173 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748
JBrowse link
regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 involved_in ISO (PMID:15286807) RGD PMID:15286807 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    cellular process 18359
      cellular developmental process 4543
        cell differentiation 4448
          myeloid cell differentiation 443
            myeloid leukocyte differentiation 238
              monocyte differentiation 35
                negative regulation of monocyte differentiation 7
                positive regulation of monocyte differentiation 11
                regulation of monocyte differentiation + 19
Path 2
Term Annotations click to browse term
  biological_process 19497
    developmental process 6889
      anatomical structure development 6306
        multicellular organism development 5727
          system development 5373
            immune system development 1105
              hematopoietic or lymphoid organ development 1038
                hemopoiesis 986
                  myeloid cell differentiation 443
                    myeloid leukocyte differentiation 238
                      monocyte differentiation 35
                        negative regulation of monocyte differentiation 7
                        positive regulation of monocyte differentiation 11
                        regulation of monocyte differentiation + 19
paths to the root