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ONTOLOGY REPORT - ANNOTATIONS

Term:monocyte differentiation
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Accession:GO:0030224 term browser browse the term
Definition:The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
Synonyms:exact_synonym: monocyte cell differentiation


show annotations for term's descendants           Sort by:
monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA		 (PMID:21149635)
GO_REF:0000107		 RGD
Ensembl		 PMID:21149635 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of ISO MGI:1856333 (PMID:9215625) RGD PMID:9215625 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 acts_upstream_of_or_within ISO (PMID:19109256) RGD PMID:19109256 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Fasn fatty acid synthase involved_in IEA
ISO		 GO_REF:0000107
MGI:3765070 (PMID:25565205)		 Ensembl
RGD		 PMID:25565205 GO_REF:0000107 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of ISO MGI:3849457 (PMID:19479052) RGD PMID:19479052 NCBI chr 6:125,865,205...125,895,674
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO MGI:96553 (PMID:19109256) RGD PMID:19109256 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il31ra interleukin 31 receptor A involved_in ISO (PMID:11877449) RGD PMID:11877449 NCBI chr 2:45,851,073...45,922,300
Ensembl chr 2:44,122,624...44,183,767 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:18326819) RGD PMID:18326819 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:1861125 (PMID:16324150) RGD PMID:16324150 NCBI chr10:83,641,851...83,685,560
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO MGI:1857491 (PMID:18326819) RGD PMID:18326819 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO
ISS		 (PMID:1912569)
GO_REF:0000024		 RGD
UniProt		 PMID:1912569 GO_REF:0000024 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Pde1b phosphodiesterase 1B involved_in ISO (PMID:14687666) RGD PMID:14687666 NCBI chr 7:136,505,834...136,533,034
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO (PMID:14687666) RGD PMID:14687666 NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pir pirin acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:20010624)
GO_REF:0000033		 RGD
GO_Central		 PMID:20010624 GO_REF:0000033 NCBI chr  X:33,740,428...33,851,049
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:9568716) RGD PMID:9568716 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Sp3 Sp3 transcription factor acts_upstream_of_or_within ISO MGI:2182438 (PMID:12676787) RGD PMID:12676787 NCBI chr 3:78,219,421...78,272,318
Ensembl chr 3:57,812,075...57,860,342 		JBrowse link
G Thoc5 THO complex subunit 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19015024)		 UniProt
Ensembl
RGD		 PMID:19015024 GO_REF:0000024 GO_REF:0000107 NCBI chr14:83,982,302...84,016,193
Ensembl chr14:79,758,917...79,792,718 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO
IEA		 (PMID:21149635)
GO_REF:0000107		 RGD
Ensembl		 PMID:21149635 GO_REF:0000107 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
negative regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcs amyloid P component, serum involved_in IEA
ISO		 GO_REF:0000107
(PMID:14607961)		 Ensembl
RGD		 PMID:14607961 GO_REF:0000107 NCBI chr13:87,905,532...87,906,508
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:26542173) RGD PMID:26542173 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within ISO MGI:3849457 (PMID:19479052) RGD PMID:19479052 NCBI chr 6:125,865,205...125,895,674
Ensembl chr 6:120,135,436...120,166,089 		JBrowse link
G Hoxa7 homeobox A7 involved_in ISO
IEA		 (PMID:14704364)
GO_REF:0000107		 RGD
Ensembl		 PMID:14704364 GO_REF:0000107 NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:81,314,625...81,317,659 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386884 (PMID:9620849)		 Ensembl
RGD		 PMID:9620849 GO_REF:0000107 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Mir125b1 microRNA 125b-1 involved_in ISO (PMID:28389358) RGD PMID:28389358 NCBI chr 8:50,850,036...50,850,122
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 involved_in ISO (PMID:28389358) RGD PMID:28389358 NCBI chr11:29,732,572...29,732,659 JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO
ISS		 (PMID:9924025)
GO_REF:0000024		 RGD
UniProt		 PMID:9924025 GO_REF:0000024 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Zbtb46 zinc finger and BTB domain containing 46 acts_upstream_of_or_within ISO MGI:5320483 (PMID:22615127) RGD PMID:22615127 NCBI chr 3:188,874,826...188,949,005
Ensembl chr 3:168,499,583...168,568,782 		JBrowse link
positive regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acin1 apoptotic chromatin condensation inducer 1 involved_in ISO (PMID:12393560) RGD PMID:12393560 NCBI chr15:32,072,121...32,117,004
Ensembl chr15:28,102,112...28,147,001 		JBrowse link
G Cd4 Cd4 molecule involved_in ISO
IEA		 (PMID:24942581)
GO_REF:0000107		 RGD
Ensembl		 PMID:24942581 GO_REF:0000107 NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:157,668,878...157,695,191 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
IEA		 (PMID:24942581)
GO_REF:0000107		 RGD
Ensembl		 PMID:24942581 GO_REF:0000107 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (PMID:9215625) RGD PMID:9215625 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 involved_in ISO (PMID:19569129) RGD PMID:19569129 NCBI chr 5:165,245,019...165,293,994
Ensembl chr 5:159,961,928...160,010,939 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein involved_in ISO (PMID:17713547) RGD PMID:17713547 NCBI chr 7:72,692,364...72,706,983
Ensembl chr 7:70,807,581...70,822,078 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:28389358) RGD PMID:28389358 NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:134,337,698...134,346,934 		JBrowse link
G Il34 interleukin 34 involved_in ISO
IBA
IEA		 (PMID:23409120)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:23409120 GO_REF:0000033 GO_REF:0000107 NCBI chr19:55,624,368...55,690,576
Ensembl chr19:38,714,991...38,764,000 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA murine WEHI-3B D+ cells with or without retinoic acid RGD PMID:7947389 RGD:2291846 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISO
ISS		 (PMID:26542173)
GO_REF:0000024		 RGD
UniProt		 PMID:26542173 GO_REF:0000024 NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
regulation of monocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp1 forkhead box P1 involved_in ISO (PMID:15286807) RGD PMID:15286807 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    developmental process 7139
      cellular developmental process 4830
        cell differentiation 4829
          myeloid cell differentiation 516
            myeloid leukocyte differentiation 288
              monocyte differentiation 36
                negative regulation of monocyte differentiation 9
                positive regulation of monocyte differentiation 11
                regulation of monocyte differentiation + 21
Path 2
Term Annotations click to browse term
  biological_process 20546
    developmental process 7139
      cellular developmental process 4830
        cell differentiation 4829
          cell development 3350
            hemopoiesis 1083
              leukocyte differentiation 688
                myeloid leukocyte differentiation 288
                  monocyte differentiation 36
                    negative regulation of monocyte differentiation 9
                    positive regulation of monocyte differentiation 11
                    regulation of monocyte differentiation + 21
paths to the root