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ONTOLOGY REPORT - ANNOTATIONS


Term:neutrophil differentiation
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Accession:GO:0030223 term browser browse the term
Definition:The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
Synonyms:exact_synonym: neutrophil cell differentiation;   neutrophil granulocyte differentiation;   neutrophil granulocytopoiesis



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neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAP1 BRCA1 associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008
JBrowse link
G CSF2 colony stimulating factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3842881|PMID:19109256) Ensembl
Ensembl
MGI
PMID:19109256 GO_REF:0000107 MGI:3842881 NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
JBrowse link
G DHRS7B dehydrogenase/reductase 7B involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:21,126,964...21,191,420
Ensembl chr17:21,123,364...21,193,265
JBrowse link
G FASN fatty acid synthase involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G IL17C interleukin 17C acts_upstream_of_or_within ISO (MGI:2388222|PMID:12077275) MGI PMID:12077275 MGI:2388222 NCBI chr16:88,638,572...88,640,468
Ensembl chr16:88,638,572...88,640,468
JBrowse link
G JAGN1 jagunal homolog 1 involved_in
NOT|involved_in
IMP
ISO
(PMID:25129144)
(MGI:5604054|PMID:25129145)
UniProt
UniProt
UniProt
PMID:25129144 PMID:25129145 MGI:5604054 NCBI chr 3:9,890,610...9,894,349
Ensembl chr 3:9,890,574...9,894,349
JBrowse link
G LBR lamin B receptor involved_in ISS
IEA
UniProt
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:225,401,502...225,428,821
Ensembl chr 1:225,401,502...225,428,925
JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IMP (PMID:17063141) UniProt
UniProt
PMID:17063141 NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
JBrowse link
negative regulation of neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
(PMID:21873635)
(MGI:1266928|PMID:9620849)
Ensembl
GO_Central
Ensembl
MGI
PMID:9620849 PMID:21873635 GO_REF:0000107 MGI:1266928 NCBI chr 2:233,060,342...233,207,903
Ensembl chr 2:233,059,967...233,207,903
JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 8:125,430,358...125,438,403
Ensembl chr 8:125,430,358...125,438,403
JBrowse link
positive regulation of neutrophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EVI2B ecotropic viral integration site 2B involved_in IBA
ISS
(PMID:21873635) GO_Central
UniProt
GO_Central
UniProt
PMID:21873635 GO_REF:0000024 NCBI chr17:31,303,770...31,314,054
Ensembl chr17:31,303,770...31,314,105
JBrowse link
G IKZF1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (MGI:2654310|PMID:12406904) MGI PMID:12406904 MGI:2654310 NCBI chr 7:50,303,455...50,405,101
Ensembl chr 7:50,304,068...50,405,101
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19656
    developmental process 7515
      cellular developmental process 4995
        cell differentiation 4972
          leukocyte differentiation 704
            myeloid leukocyte differentiation 270
              granulocyte differentiation 48
                neutrophil differentiation 12
                  negative regulation of neutrophil differentiation 2
                  positive regulation of neutrophil differentiation 2
                  regulation of neutrophil differentiation + 4
Path 2
Term Annotations click to browse term
  biological_process 19656
    developmental process 7515
      anatomical structure development 6875
        multicellular organism development 5795
          system development 5324
            immune system development 1245
              hematopoietic or lymphoid organ development 1174
                hemopoiesis 1125
                  leukocyte differentiation 704
                    myeloid leukocyte differentiation 270
                      granulocyte differentiation 48
                        neutrophil differentiation 12
                          negative regulation of neutrophil differentiation 2
                          positive regulation of neutrophil differentiation 2
                          regulation of neutrophil differentiation + 4
paths to the root