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ONTOLOGY REPORT - ANNOTATIONS


Term:eosinophil differentiation
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Accession:GO:0030222 term browser browse the term
Definition:The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.
Synonyms:exact_synonym: eosinophil cell differentiation
 related_synonym: eosinophil cell development;   eosinophil development
 alt_id: GO:0035856



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eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA1 GATA binding protein 1 involved_in ISO (PMID:8507862) BHF-UCL PMID:8507862 NCBI chr  X:41,088,724...41,092,190
Ensembl chr  X:48,945,394...48,953,126
JBrowse link
G IL25 interleukin 25 acts_upstream_of_or_within ISO (MGI:2388222|PMID:12077275) MGI PMID:12077275 MGI:2388222 NCBI chr14:4,191,888...4,195,043
Ensembl chr14:22,286,347...22,289,498
JBrowse link
eosinophil fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GATA1 GATA binding protein 1 involved_in ISO (PMID:12045236) BHF-UCL PMID:12045236 NCBI chr  X:41,088,724...41,092,190
Ensembl chr  X:48,945,394...48,953,126
JBrowse link
G GATA2 GATA binding protein 2 involved_in ISO (PMID:12045236) BHF-UCL PMID:12045236 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035
JBrowse link
positive regulation of eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL5 interleukin 5 ISO RGD PMID:10529595 PMID:10727846 RGD:2303509 RGD:2303750 NCBI chr 5:127,955,377...127,961,726
Ensembl chr 5:134,119,608...134,121,675
JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) CACAO PMID:23515163 MGI:5488531 NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12661
    developmental process 5914
      cellular developmental process 3837
        cell development 2200
          eosinophil differentiation 5
            eosinophil fate commitment + 2
            negative regulation of eosinophil differentiation 0
            positive regulation of eosinophil differentiation 2
            regulation of eosinophil differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 12661
    developmental process 5914
      anatomical structure development 5517
        multicellular organism development 5046
          system development 4748
            immune system development 990
              hematopoietic or lymphoid organ development 928
                hemopoiesis 880
                  leukocyte differentiation 556
                    myeloid leukocyte differentiation 223
                      granulocyte differentiation 41
                        eosinophil differentiation 5
                          eosinophil fate commitment + 2
                          negative regulation of eosinophil differentiation 0
                          positive regulation of eosinophil differentiation 2
                          regulation of eosinophil differentiation + 2
paths to the root