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ONTOLOGY REPORT - ANNOTATIONS
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Term:
eosinophil differentiation
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Accession:
GO:0030222
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Definition:
The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.
Synonyms:
exact_synonym:
eosinophil cell differentiation
related_synonym:
eosinophil cell development; eosinophil development
alt_id:
GO:0035856
show annotations for term's descendants Sort by:
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Rat (5)
Mouse (5)
Human (5)
Chinchilla (5)
Bonobo (5)
Dog (5)
Squirrel (5)
Pig (5)
All
Genes (5)
eosinophil differentiation
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Gata1
GATA binding protein 1
ISO
(PMID:8507862)
RGD
PMID:8507862
NCBI chr X:15,273,937...15,281,759
Ensembl chr X:15,378,789...15,382,066
G
Il25
interleukin 25
ISO
(MGI:2388222|PMID:12077275)
RGD
PMID:12077275
MGI:2388222
NCBI chr15:33,594,852...33,599,692
Ensembl chr15:33,596,301...33,599,685
eosinophil fate commitment
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Gata1
GATA binding protein 1
ISO
(PMID:12045236)
RGD
PMID:12045236
NCBI chr X:15,273,937...15,281,759
Ensembl chr X:15,378,789...15,382,066
G
Gata2
GATA binding protein 2
ISO
(PMID:12045236)
RGD
PMID:12045236
NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
positive regulation of eosinophil differentiation
Symbol
Object Name
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Il5
interleukin 5
IDA
RGD
PMID:10727846
,
PMID:10529595
RGD:2303509
,
RGD:2303750
NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
G
Trib1
tribbles pseudokinase 1
ISO
(MGI:5488531|PMID:23515163)
RGD
PMID:23515163
MGI:5488531
NCBI chr 7:99,954,492...99,961,026
Ensembl chr 7:99,954,492...99,961,026
Term paths to the root
one shortest
all shortest
one longest
all longest
one shortest and longest
all
Path 1
Term
Annotations
biological_process
20044
developmental process
6822
cellular developmental process
4463
cell development
2446
eosinophil differentiation
5
eosinophil fate commitment
+
2
negative regulation of eosinophil differentiation
0
positive regulation of eosinophil differentiation
2
regulation of eosinophil differentiation
+
2
Path 2
Term
Annotations
biological_process
20044
developmental process
6822
anatomical structure development
6288
multicellular organism development
5764
system development
5296
immune system development
1081
hematopoietic or lymphoid organ development
1016
hemopoiesis
964
leukocyte differentiation
601
myeloid leukocyte differentiation
234
granulocyte differentiation
44
eosinophil differentiation
5
eosinophil fate commitment
+
2
negative regulation of eosinophil differentiation
0
positive regulation of eosinophil differentiation
2
regulation of eosinophil differentiation
+
2