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ONTOLOGY REPORT - ANNOTATIONS


Term:eosinophil differentiation
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Accession:GO:0030222 term browser browse the term
Definition:The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.
Synonyms:exact_synonym: eosinophil cell differentiation
 related_synonym: eosinophil cell development;   eosinophil development
 alt_id: GO:0035856



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eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata1 GATA binding protein 1 involved_in ISO (PMID:8507862) RGD PMID:8507862 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Il25 interleukin 25 acts_upstream_of_or_within ISO (MGI:2388222|PMID:12077275) RGD PMID:12077275 MGI:2388222 NCBI chr15:28,408,766...28,412,157
Ensembl chr15:28,408,842...28,411,893
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:11823534) RGD PMID:11823534 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO
GO_REF:0000107
(PMID:12393707)
Ensembl
RGD
PMID:12393707 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
eosinophil fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata1 GATA binding protein 1 involved_in ISO (PMID:12045236) RGD PMID:12045236 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gata2 GATA binding protein 2 involved_in ISO (PMID:12045236) RGD PMID:12045236 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
positive regulation of eosinophil differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il5 interleukin 5 IDA RGD PMID:10727846 PMID:10529595 RGD:2303509, RGD:2303750 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Trib1 tribbles pseudokinase 1 involved_in ISO (MGI:5488531|PMID:23515163) RGD PMID:23515163 MGI:5488531 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20295
    developmental process 7050
      cellular developmental process 4751
        cell development 3306
          eosinophil differentiation 7
            eosinophil fate commitment + 2
            negative regulation of eosinophil differentiation 0
            positive regulation of eosinophil differentiation 2
            regulation of eosinophil differentiation + 2
Path 2
Term Annotations click to browse term
  biological_process 20295
    cellular process 18772
      cellular developmental process 4751
        cell differentiation 4750
          cell development 3306
            hemopoiesis 1062
              myeloid cell differentiation 506
                myeloid leukocyte differentiation 281
                  granulocyte differentiation 52
                    eosinophil differentiation 7
                      eosinophil fate commitment + 2
                      negative regulation of eosinophil differentiation 0
                      positive regulation of eosinophil differentiation 2
                      regulation of eosinophil differentiation + 2
paths to the root